Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ITLN2 Gene

protein-coding   GIFtS: 47
GCID: GC01M160914

Intelectin 2

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Intelectin 21 2
Endothelial Lectin HL-22 3
HL22 5
HL-22
intelectin-22

External Ids:    HGNC: 205991   Entrez Gene: 1426832   Ensembl: ENSG000001587647   OMIM: 6098745   UniProtKB: Q8WWU73   

Export aliases for ITLN2 gene to outside databases

Previous GC identifers: GC01M157692 GC01M158131 GC01M157727 GC01M159181 GC01M132271


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ITLN2 Gene: 
ITLN2 (intelectin 2) is a protein-coding gene. Diseases associated with ITLN2 include endotheliitis. GO annotations related to this gene include receptor binding. An important paralog of this gene is ITLN1.

UniProtKB/Swiss-Prot: ITLN2_HUMAN, Q8WWU7
Function: May play a role in the defense system against pathogens (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ITLN2 gene promoter:
         AhR   USF1   Pax-5   LUN-1   C/EBPalpha   Arnt   YY1   Gfi-1   CHOP-10   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITLN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ITLN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITLN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q23   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q22-q23.5

ITLN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITLN2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M160914:  view genomic region     (about GC identifiers)

Start:
160,914,815 bp from pter      End:
160,924,589 bp from pter
Size:
9,775 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ITLN2_HUMAN, Q8WWU7 (See protein sequence)
Recommended Name: Intelectin-2 precursor  
Size: 325 amino acids; 36212 Da
Subcellular location: Secreted (Potential)
Secondary accessions: Q5VYI0

Explore the universe of human proteins at neXtProt for ITLN2: NX_Q8WWU7

Explore proteomics data for ITLN2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WWU7

  • ITLN2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ITLN2 Protein Expression
    REFSEQ proteins: NP_543154.1  
    ENSEMBL proteins: 
     ENSP00000357008  

    Human Recombinant Protein Products for ITLN2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ITLN2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ITLN2
    GenScript Custom Purified and Recombinant Proteins Services for ITLN2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ITLN2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    ITLN2 for ontologies           About GeneDecksing



    ITLN2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for ITLN2 (Intelectin-2)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ITLN2
    GenScript Custom Superior Antibodies Services for ITLN2
    Novus Biologicals ITLN2 Antibodies
    Abcam antibodies for ITLN2
    Cloud-Clone Corp. Antibodies for ITLN2 
    Search ThermoFisher Antibodies for ITLN2
    LSBio Antibodies in human, mouse, rat for ITLN2 

    Assay Products for ITLN2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ITLN2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ITLN2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ITLN2 
    Cloud-Clone Corp. CLIAs for ITLN2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FIBC: Fibrinogen C domain containing

    2 InterPro protein domains:
     IPR014716 Fibrinogen_a/b/g_C_1
     IPR002181 Fibrinogen_a/b/g_C_dom

    Graphical View of Domain Structure for InterPro Entry Q8WWU7

    ProtoNet protein and cluster: Q8WWU7

    UniProtKB/Swiss-Prot: ITLN2_HUMAN, Q8WWU7
    Similarity: Contains 1 fibrinogen C-terminal domain


    ITLN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ITLN2_HUMAN, Q8WWU7
    Function: May play a role in the defense system against pathogens (By similarity)

    Animal Models:

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ITLN2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ITLN2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ITLN2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ITLN2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ITLN2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ITLN2
    SwitchGear 3'UTR luciferase reporter plasmidITLN2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ITLN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITLN2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ITLN2
    Sirion Biotech Customized adenovirus for overexpression of ITLN2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ITLN2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITLN2 (NM_080878)
    Sino Biological Human cDNA Clone for ITLN2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITLN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITLN2
    Sirion Biotech Customized lentivirus for stable overexpression of ITLN2 
                         Customized lentivirus expression plasmids for stable overexpression of ITLN2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ITLN2
    Search LifeMap BioReagents cell lines for ITLN2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITLN2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ITLN2

    1 Interacting protein for ITLN2 (Q8WWU73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFRP005333I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ITLN2

    Search CenterWatch for drugs/clinical trials and news about ITLN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ITLN2 gene: 
    NM_080878.2  

    Unigene Cluster for ITLN2:

    Intelectin 2
    Hs.385631  [show with all ESTs]
    Unigene Representative Sequence: AY358905
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368029(uc001fxd.3 uc009wts.3 uc010pju.2) ENST00000494442
    ENST00000490489
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ITLN2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ITLN2
    SwitchGear 3'UTR luciferase reporter plasmidITLN2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ITLN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITLN2
    Clone
    Products:
         
    OriGene clones in human, mouse for ITLN2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITLN2 (NM_080878)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITLN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITLN2
    Sirion Biotech Customized lentivirus for stable overexpression of ITLN2 
                         Customized lentivirus expression plasmids for stable overexpression of ITLN2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ITLN2
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ITLN2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITLN2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITLN2

    Additional mRNA sequence: 

    AY065973.1 AY358905.1 BC117225.1 BC143339.1 BC143341.1 

    1 DOTS entry:

    DT.97838744 

    12 AceView cDNA sequences:

    BE045344 AY065973 BM993101 NM_080878 AY358905 BI821675 BM998678 BM993198 
    BF515308 BG482966 BX505934 BE327604 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ITLN2 expression in normal human tissues (normalized intensities)      ITLN2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGCATTGGA
    ITLN2 Expression
    About this image


    ITLN2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Intestine (Gastrointestinal Tract)    fully expand to see all 2 entries
             small intestine ; glandular cells   
     
     Colon (Gastrointestinal Tract)
             colon ; glandular cells   
     
     Lung (Respiratory System)
             lung ; macrophages   
     
     Gut Tube (Gastrointestinal Tract)
             Primitive gut tube-like cells ( A scalable, suspension protocol for derivation of...
     
     Inner Cell Mass (Early Embryonic Tissues)
             Line H9 (WA09)

    See ITLN2 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.385631

    UniProtKB/Swiss-Prot: ITLN2_HUMAN, Q8WWU7
    Tissue specificity: Expressed only in the small intestine

        SABiosciences Custom PCR Arrays for ITLN2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ITLN2
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ITLN2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITLN2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITLN2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITLN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ITLN2 gene from 4/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    oppossum
    (Monodelphis domestica)
    Mammalia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    79(a)
    75(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    2(164389016-164391058)
    2(164388807-164415382)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    66(a)
    1 → many
    GL343929.1(67124-79262)
    African clawed frog
    (Xenopus laevis)
    Amphibia XEEL2 embryonic epidermal lectin 74.54(n)    AB105372.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5649581 intelectin-1-like 62.68(n)
    61.96(a)
      564958  XM_688277.1  XP_693369.1 


    ENSEMBL Gene Tree for ITLN2 (if available)
    TreeFam Gene Tree for ITLN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ITLN2 gene
    ITLN12  
    1 SIMAP similar gene for ITLN2 using alignment to 3 protein entries:     ITLN2_HUMAN (see all proteins):
    ITLN1

    ITLN2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/361 SNPs in ITLN2 are shown (see all 361)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22434701,2
    C--160914332(+) GGAGTG/ACAATG 1 -- ds50019Minor allele frequency- A:0.02NA WA CSA EA 369
    rs1401940151,2
    --160914366(+) CTCTGC/TCTCCC 1 -- ds50010--------
    rs618021661,2
    C,F--160914529(+) GCCTCG/AGCCTC 1 -- ds50012Minor allele frequency- A:0.50NA 4
    rs730120911,2
    C,F--160914606(+) TTTTTT/AATATC 1 -- ds50013Minor allele frequency- A:0.09WA CSA 122
    rs1838398021,2
    C--160914885(+) TAGCCA/GGGGTT 1 -- ut310--------
    rs2002571251,2
    --160914905(+) GTTCTC/TGCCCT 1 -- ut310--------
    rs67019201,2
    C,F,H--160914917(+) ACACCG/ACAGAG 1 -- ut31 ese312Minor allele frequency- A:0.03NS EA NA WA EU 2625
    rs1869343621,2
    C--160914955(+) CAGCCA/GCCTCC 2 A V mis10--------
    rs1499289061,2
    C,F--160915019(+) AAAGGC/TGGAGA 2 T A mis12Minor allele frequency- T:0.00NA EU 5873
    rs1836528831,2
    C--160915037(+) ACACTA/GACGGG 2 Q * stg10--------

    HapMap Linkage Disequilibrium report for ITLN2 (160914815 - 160924589 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ITLN2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ITLN2
    DNA2.0 Custom Variant and Variant Library Synthesis for ITLN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609874    OMIM disorders: --

    2 diseases for ITLN2:    About MalaCards
    endotheliitis    


    ITLN2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ITLN2
    Human Genome Epidemiology (HuGE) Navigator: ITLN2 (4 documents)

    Export disorders for ITLN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ITLN2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ITLN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human homologs of the Xenopus oocyte cortical granule lectin XL35. (PubMed id 11181563)1, 2, 3 Lee J.K....Pierce M. (2001)
    2. Common variants in 40 genes assessed for diabetes inc idence and response to metformin and lifestyle intervention in the diabetes pre vention program. (PubMed id 20682687)1, 4 Jablonski K.A....Florez J.C. (2010)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Up-regulation of intelectin in sheep after infection with Teladorsagia circumcincta. (PubMed id 17983620)9 French A.T....Pemberton A.D. (2008)
    10. Developmental expression of XEEL, a novel molecule of the Xenopus oocyte cortical granule lectin family. (PubMed id 12802587)9 Nagata S....Fujita N. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 142683 HGNC: 20599 AceView: ITLN2 Ensembl:ENSG00000158764 euGenes: HUgn142683
    ECgene: ITLN2 H-InvDB: ITLN2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ITLN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ITLN2 gene:
    Search GeneIP for patents involving ITLN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for ITLN2 (Intelectin-2)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ITLN2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ITLN2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ITLN2  
     OriGene qSTAR qPCR primer pairs in human, mouse for ITLN2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ITLN2   OriGene Custom Protein Services for ITLN2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ITLN2
     QIAGEN SeqTarget long-range PCR primers for resequencing ITLN2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITLN2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITLN2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITLN2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITLN2
     GenScript Custom Purified and Recombinant Proteins Services for ITLN2 GenScript cDNA clones with any tag delivered in your preferred vector for ITLN2
     GenScript Custom Assay Services for ITLN2 GenScript Custom Superior Antibodies Services for ITLN2
     GenScript Custom overexpressing Cell Line Services for ITLN2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ITLN2 promoter
     Search Chromatin IP Primers for ITLN2
     RT2 qPCR Primer Assay in human, mouse / rat ITLN2
     Search GNC Networks for ITLN2
     SABiosciences Custom PCR Arrays for ITLN2
     Search Tocris compounds for ITLN2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ITLN2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ITLN2 antibodies
     Antibodies for ITLN2
     See all of Abcam's Antibodies, Kits and Proteins for ITLN2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ITLN2
     Antibodies for ITLN2
     ELISAs for ITLN2
     CLIAs for ITLN2
     Search LifeMap BioReagents cell lines for ITLN2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITLN2
     SwitchGear 3'UTR luciferase reporter plasmids for ITLN2
     SwitchGear Promoter luciferase reporter plasmids for ITLN2
     Search ThermoFisher Antibodies for ITLN2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITLN2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ITLN2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ITLN2
    Customized:
     lentivirus for stable overexpression of ITLN2
     lentivirus expression plasmids for stable overexpression of ITLN2
     adenovirus for overexpression of ITLN2
     LSBio Antibodies in human, mouse, rat for ITLN2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ITLN2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4