Aliases for ITLN1 Gene
External Ids for ITLN1 Gene
Previous GeneCards Identifiers for ITLN1 Gene
GeneCards Summary for ITLN1 Gene
ITLN1 (Intelectin 1) is a Protein Coding gene. Diseases associated with ITLN1 include Obesity and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Immune System and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is ITLN2.
UniProtKB/Swiss-Prot for ITLN1 Gene
Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.