ITGB3BP Gene
protein-coding GIFtS: 53
GCID: GC01M063906
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|
integrin beta 3 binding protein (beta3-endonexin)
| |
Aliases
for ITGB3BP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Integrin Beta 3 Binding Protein (Beta3-Endonexin)1 2 | | Nuclear Receptor-Interacting Factor 32 3 | | NRIF31 2 3 5 | | CENP-R2 3 | | CENPR1 2 3 | | Beta 3 Endonexin2 | | HSU371391 2 | | Beta-3-Endonexin1 | | TAP201 2 | | Centromere Protein R2 | | Integrin Beta-3-Binding Protein2 3 | | Beta-3-Endonexin1 |
Export aliases for ITGB3BP gene to outside databasesPrevious GC identifers: GC01M063742 GC01M062829 GC01M063264 GC01M063276 GC01M063246 GC01M063618 GC01M063679 GC01M062014 |
Summaries
for ITGB3BP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ITGB3BP:
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclearreceptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor ofNF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediatedsignaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosomeassociated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-Ato the centromere. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Sep 2011)
UniProtKB/Swiss-Prot: CENPR_HUMAN, Q13352Function: Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not otherisoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in aligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D,progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as atranscriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with thetransactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via acaspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases.May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal)complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progressionand chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via itsinteraction with the CENPA-NAC complex
Gene Wiki entry for ITGB3BP
|
Genomic Views
for ITGB3BP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ITGB3BP gene promoter:
Bach2 Pax-2a POU6F1 (c2) FOXL1 POU2F1 POU2F1a POU2F1b FOXJ2 (long isoform) FOXJ2 POU2F1c
Other transcription factors
Search SABiosciences Chromatin IP Primers for ITGB3BP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITGB3BP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p31.3 Ensembl cytogenetic band: 1p31.3 HGNC cytogenetic band: 1p31.3ITGB3BP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M063906: view genomic region
(about GC identifiers)
Start:
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63,906,441 bp from pter |
End:
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64,059,392 bp from pter |
Size:
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152,952 bases |
Orientation:
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minus strand |
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Proteins
for ITGB3BP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CENPR_HUMAN, Q13352 (See
protein sequence)Recommended Name: Centromere protein R Size: 177 amino acids; 20194 Da
Subunit: Homodimer; mediated by the coiled coil domain. Isoform 3, but not other isoforms, interacts with thecytoplasmic tail of integrin ITGB3. The relevance of the interaction with ITGB3 is however uncertain, since isoform 3is mainly nuclear. Interacts with CCNA2 and MTA1. Interacts with NFKB1 NF-kappa-B subunit. Component of the CENPA-CADcomplex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts withthe CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU
Subcellular location: Isoform 1: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore
Subcellular location: Isoform 2: Nucleus
Subcellular location: Isoform 3: Nucleus. Cytoplasm. Note=Isoform 3 is predominantly nuclear and weakly cytoplasmic
Subcellular location: Isoform 4: Cytoplasm
Sequence caution: Sequence=AAH14385.1; Type=Erroneous initiation;
Secondary accessions: B2R7D8 Q13353 Q5RJ42 Q5RJ44 Q5RJ45 Q7KYX2 Q96CD5 Q9UKB6Alternative splicing: 5 isoforms: Q13352-1 Q13352-2 Q13352-3 Q13352-4 Q13352-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ITGB3BP: NX_Q13352
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13352
ITGB3BP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001193668.1 NP_055103.3
ENSEMBL proteins: ENSP00000432904 ENSP00000271002 ENSP00000360133 ENSP00000283568 Reactome Protein details: Q13352
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ITGB3BP for ontologies About GeneDecksing
ITGB3BP Antibody Products:
Assay Products for ITGB3BP: |
Protein
Domains /
Families
for ITGB3BP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ITGB3BP for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q13352ProtoNet protein and cluster: Q13352 UniProtKB/Swiss-Prot: CENPR_HUMAN, Q13352Domain: The DD1 domain (also called RepD1 domain) mediates the corepressor function and is essential in the triggeringof apoptosisDomain: Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, a motif known to be important for the association with nuclearreceptors. Such motif, which is required for an efficient association with nuclear receptors, is however not essentialDomain: Contains one Leu-Xaa-Xaa-Ile-Leu (LXXIL) motif, which is essential for the association with nuclear receptors |
Function
for ITGB3BP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CENPR_HUMAN, Q13352Function: Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not otherisoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in aligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D,progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as atranscriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with thetransactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via acaspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases.May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal)complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progressionand chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via itsinteraction with the CENPA-NAC complexInduction: By estrogen
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITGB3BP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ITGB3BP (NM_014288) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ITGB3BP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITGB3BP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITGB3BP |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ITGB3BP for ontologies About GeneDecksing
|
Pathways & Interactions
for ITGB3BP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | M Phase | | | 2 | RSF Complex Binds the Centromere. | | | 3 | Resolution of Sister Chromatid Cohesion | | | 4 | Cell death signalling via NRAGE, NRIF and NADE | | | 5 | Cell Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for ITGB3BP
1  GeneGo (Thomson Reuters) Pathway for ITGB3BP
5/20 
Reactome Pathways for ITGB3BP (see all 20)
ITGB3BP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ITGB3BP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/65 Interacting proteins for ITGB3BP (Q133522, 3 ENSP000002710024) via UniProtKB, MINT, STRING, and/or I2D (see all 65)About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table
ITGB3BP for ontologies About GeneDecksing
|
Drugs & Compounds
for ITGB3BP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ITGB3BP for compounds About GeneDecksing
 Browse Tocris compounds for ITGB3BP
1 HMDB Compound for ITGB3BP About this table
3 Novoseek chemical compound relationships for ITGB3BP gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| fibrinogen |
31.8 |
1 |
9182673 (1) |
| serine |
20.3 |
1 |
8939656 (1) |
| calcium |
0 |
1 |
17059412 (1) |
Search CenterWatch for drugs/clinical trials and news about ITGB3BP / CENPR
|
Transcripts
for ITGB3BP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ITGB3BP gene (2 alternative transcripts): NM_001206739.1 NM_014288.4 Unigene Cluster for ITGB3BP: Integrin beta 3 binding protein (beta3-endonexin) Hs.166539 [show with all ESTs]Unigene Representative Sequence: BG38761515 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000492655 ENST00000489099(uc001dbc.2 uc001dba.2) ENST00000271002
ENST00000371092(uc001dbb.2) ENST00000461681 ENST00000463803 ENST00000478538
ENST00000476508 ENST00000460394 ENST00000462285(uc009wak.1) ENST00000489863
ENST00000465781 ENST00000460251 ENST00000478138 ENST00000283568
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITGB3BP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITGB3BP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ITGB3BP (NM_014288) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ITGB3BP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITGB3BP |
Additional cDNA sequence: AF175306.1 AK309622.1 AK312944.1 BC009929.2 BC014385.1 NR_045147.1 U37139.1 20 DOTS entries: DT.86853560 DT.121339551 DT.100037033 DT.91770984 DT.91816133 DT.70100152 DT.91770973 DT.102835215 DT.102835216 DT.121339540 DT.92036895 DT.99999487 DT.100821955 DT.121339421 DT.40111806 DT.40291902 DT.91770986 DT.97820153 DT.100773434 DT.91838081 24/168 AceView cDNA sequences (see all 168): AW769900 AA873717 BM479093 BG403674 BX113691 AA902960 BG185975 CB306917 AA397971 CA430272 AA732664 BM975049 CR596268 BG215608 BX102090 BX394996 AA831178 BM790968 CB162919 BG184897 BQ955600 C21180 BQ223942 AA043805
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ITGB3BP (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ITGB3BP
|
Expression
for ITGB3BP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ITGB3BP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATAAAAGTG
About this image
See ITGB3BP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ITGB3BP
SOURCE GeneReport for Unigene cluster: Hs.166539
UniProtKB/Swiss-Prot: CENPR_HUMAN, Q13352Tissue specificity: Widely expressed. Expressed in spleen, thymus, prostate, ovary, small intestine and white bloodcells. Highly expressed in testis and colon. Isoform 4 is expressed in platelets, lymphocytes and granulocytes
SABiosciences Expression via Pathway-Focused PCR Array including ITGB3BP:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ITGB3BP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ITGB3BP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITGB3BP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITGB3BP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITGB3BP |
Orthologs
for ITGB3BP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ITGB3BP gene from 3/7 species (see all 7) About this table
ENSEMBL Gene Tree for ITGB3BP (if available)
TreeFam Gene Tree for ITGB3BP (if available) |
Paralogs
for ITGB3BP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ITGB3BP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ITGB3BP (63906441 - 64059392 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ITGB3BP: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITGB3BP |
|
Disorders
/ Diseases
for ITGB3BP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ITGB3BP for disorders About GeneDecksing
OMIM gene information: 605494
OMIM disorders: --
4  diseases for ITGB3BP: About MalaCardsbreast cancer thyroiditis prostatitis neuronitis
1 Novoseek disease relationship for ITGB3BP gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| breast cancer |
19.3 |
8 |
15082778 (5), 17308120 (2), 18521086 (1) |
Human Genome Epidemiology (HuGE) Navigator: ITGB3BP (1 document)
Export disorders for ITGB3BP gene to outside databases
|
Publications
for ITGB3BP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ITGB3BP gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with ITGB3BP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit. (PubMed id 7593198)1, 2, 3, 9 Shattil S.J.... Ginsberg M.H. (1995)
- NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors. (PubMed id 10490654)1, 2, 3 Li D.... Samuels H.H. (1999)
- Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation. (PubMed id 11713274)1, 2, 9 Li D.... Samuels H.H. (2001)
- Affinity modulation of platelet integrin alphaIIbbeta3 by beta3- endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail. (PubMed id 9182673)1, 2, 9 Kashiwagi H.... Shattil S.J. (1997)
- The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells. (PubMed id 15082778)1, 2, 9 Li D.... Samuels H.H. (2004)
- The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 2 Okada M....Fukagawa T. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2 Foltz D.R....Cleveland D.W. (2006)
- Metastasis-associated protein 1 interacts with NRIF3, an estrogen- inducible nuclear receptor coregulator. (PubMed id 15254226)1, 2 Talukder A.H.... Kumar R. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for ITGB3BP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ITGB3BP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ITGB3BP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ITGB3BP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ITGB3BP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ITGB3BP gene:
Search GeneIP for patents involving ITGB3BP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ITGB3BP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ITGB3BP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ITGB3BP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ITGB3BP | | | OriGene Protein Over-expression Lysate for ITGB3BP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ITGB3BP | | OriGene 3'-UTR Clone for ITGB3BP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ITGB3BP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ITGB3BP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ITGB3BP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ITGB3BP | | OriGene Custom Protein Services for ITGB3BP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ITGB3BP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ITGB3BP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ITGB3BP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ITGB3BP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ITGB3BP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ITGB3BP |
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| | | | Search Tocris compounds for ITGB3BP |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITGB3BP |
|  |  |  | | | | Search ThermoFisher Antibodies for ITGB3BP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITGB3BP |
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