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Aliases for ITGB2-AS1 Gene

Subcategory (RNA class) for ITGB2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for ITGB2-AS1 Gene

  • ITGB2 Antisense RNA 1 2 3 5
  • ITGB2 Antisense RNA 1 (Non-Protein Coding) 2

External Ids for ITGB2-AS1 Gene

Previous GeneCards Identifiers for ITGB2-AS1 Gene

  • GC21P046343

Summaries for ITGB2-AS1 Gene

GeneCards Summary for ITGB2-AS1 Gene

ITGB2-AS1 (ITGB2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ITGB2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ITGB2-AS1 Gene

Genomics for ITGB2-AS1 Gene

GeneHancer (GH) Regulatory Elements for ITGB2-AS1 Gene

Promoters and enhancers for ITGB2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21I044916 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 14.2 +3.6 3579 16.8 HDGF PKNOX1 CLOCK SMAD1 NEUROD1 SIN3A FEZF1 ZBTB7B IRF4 ZNF207 ITGB2 POFUT2 UBE2G2 ENSG00000273027 TRPM2 ENSG00000184441 PTTG1IP ITGB2-AS1 ENSG00000215447 C21orf2
GH21I044938 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.9 +19.4 19445 3 MLX DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC ZNF610 LINC01547 FAM207A ENSG00000215447 PWP2 ENSG00000184441 LINC00205 ENSG00000273027 UBE2G2 ITGB2-AS1 TRAPPC10
GH21I043920 Enhancer 1.4 Ensembl ENCODE dbSUPER 11.6 -997.9 -997850 6.3 HDGF PKNOX1 FOXA2 SMAD1 ARNT ZNF143 FOS ZNF592 MEF2D SMARCA4 RRP1B PWP2 ENSG00000184441 LINC01424 ITGB2-AS1 TRAPPC10 AGPAT3 CSTB AATBC RNU6-859P
GH21I045108 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.7 +190.0 190046 4.4 HDGF PKNOX1 ATF1 IRF4 ARID2 ATF7 RUNX3 JUNB NCOA1 ZNF592 ITGB2-AS1 SSR4P1 LINC00205 LOC105372835 ADARB1 GC21M045667
GH21I044966 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 7.1 +47.8 47777 4.6 ATF1 BRCA1 ETS1 YY1 TCF12 GLIS2 GATA2 ATF7 RXRA ZHX2 ENSG00000273027 ITGB2 LINC01547 FAM207A ITGB2-AS1 POFUT2 ENSG00000276529
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ITGB2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ITGB2-AS1 Gene

Genomic Locations for ITGB2-AS1 Gene
chr21:44,921,035-44,929,680
(GRCh38/hg38)
Size:
8,646 bases
Orientation:
Plus strand
chr21:46,340,950-46,349,595
(GRCh37/hg19)

Genomic View for ITGB2-AS1 Gene

Genes around ITGB2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ITGB2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ITGB2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ITGB2-AS1 Gene

Proteins for ITGB2-AS1 Gene

Post-translational modifications for ITGB2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ITGB2-AS1 Gene

Domains & Families for ITGB2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ITGB2-AS1 Gene

Function for ITGB2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ITGB2-AS1 Gene

Localization for ITGB2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ITGB2-AS1 Gene

Pathways & Interactions for ITGB2-AS1 Gene

SuperPathways for ITGB2-AS1 Gene

No Data Available

Interacting Proteins for ITGB2-AS1 Gene

Gene Ontology (GO) - Biological Process for ITGB2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ITGB2-AS1 Gene

Drugs & Compounds for ITGB2-AS1 Gene

No Compound Related Data Available

Transcripts for ITGB2-AS1 Gene

mRNA/cDNA for ITGB2-AS1 Gene

(10) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ITGB2-AS1 Gene

ITGB2 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ITGB2-AS1 Gene

No ASD Table

Relevant External Links for ITGB2-AS1 Gene

GeneLoc Exon Structure for
ITGB2-AS1
ECgene alternative splicing isoforms for
ITGB2-AS1

Expression for ITGB2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ITGB2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ITGB2-AS1 Gene

This gene is overexpressed in Whole Blood (x23.8) and Spleen (x7.2).

SOURCE GeneReport for Unigene cluster for ITGB2-AS1 Gene:

Hs.661035
genes like me logo Genes that share expression patterns with ITGB2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ITGB2-AS1 Gene

Orthologs for ITGB2-AS1 Gene

Evolution for ITGB2-AS1 Gene

ENSEMBL:
Gene Tree for ITGB2-AS1 (if available)
TreeFam:
Gene Tree for ITGB2-AS1 (if available)

No data available for Orthologs for ITGB2-AS1 Gene

Paralogs for ITGB2-AS1 Gene

No data available for Paralogs for ITGB2-AS1 Gene

Variants for ITGB2-AS1 Gene

Sequence variations from dbSNP and Humsavar for ITGB2-AS1 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1042297437 uncertain-significance, Leukocyte adhesion deficiency 44,920,856(+) C/T upstream_transcript_variant
rs2070947 benign, Leukocyte adhesion deficiency 44,920,928(+) A/G upstream_transcript_variant
rs371741629 uncertain-significance, Leukocyte adhesion deficiency 44,920,827(+) T/G upstream_transcript_variant
rs754249152 uncertain-significance, Leukocyte adhesion deficiency 44,920,921(+) G/A upstream_transcript_variant
rs910664081 uncertain-significance, Leukocyte adhesion deficiency 44,920,825(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ITGB2-AS1 Gene

Variant ID Type Subtype PubMed ID
esv1127077 CNV insertion 17803354
esv2723696 CNV deletion 23290073
esv2723697 CNV deletion 23290073
esv3575398 CNV gain 25503493
esv3647138 CNV loss 21293372
nsv834110 CNV loss 17160897

Additional Variant Information for ITGB2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ITGB2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ITGB2-AS1 Gene

Disorders for ITGB2-AS1 Gene

Additional Disease Information for ITGB2-AS1

No disorders were found for ITGB2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ITGB2-AS1 Gene

Publications for ITGB2-AS1 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ITGB2-AS1 Gene

Sources for ITGB2-AS1 Gene

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