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ITGB1BP2 Gene

protein-coding   GIFtS: 50
GCID: GC0XP070521

Integrin Beta 1 Binding Protein (Melusin) 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Integrin Beta 1 Binding Protein (Melusin) 21 2
CHORDC32
ITGB1BP2
MELUSIN2
Integrin Beta-1-Binding Protein 22
Melusin3

External Ids:    HGNC: 61541   Entrez Gene: 265482   Ensembl: ENSG000001471667   OMIM: 3003325   UniProtKB: Q9UKP33   

Export aliases for ITGB1BP2 gene to outside databases

Previous GC identifers: GC0XP066695 GC0XP067998 GC0XP068754 GC0XP069388 GC0XP070304 GC0XP070438 GC0XP064337


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ITGB1BP2 Gene:
ITGB1BP2 (integrin beta 1 binding protein (melusin) 2) is a protein-coding gene. GO annotations related to this gene include integrin binding and calcium ion binding. An important paralog of this gene is CHORDC1.

UniProtKB/Swiss-Prot: ITBP2_HUMAN, Q9UKP3
Function: May play a role during maturation and/or organization of muscles cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ITGB1BP2 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   NF-kappaB   CREB   E2F   E2F-1   deltaCREB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITGB1BP2 promoter sequence
   Search Chromatin IP Primers for ITGB1BP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ITGB1BP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq12-q13.1   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq12.1-q13

ITGB1BP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITGB1BP2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP070521:  view genomic region     (about GC identifiers)

Start:
70,521,584 bp from pter      End:
70,525,221 bp from pter
Size:
3,638 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ITBP2_HUMAN, Q9UKP3 (See protein sequence)
Recommended Name: Integrin beta-1-binding protein 2  
Size: 347 amino acids; 38382 Da
Subunit: Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs
only in absence of calcium
Secondary accessions: Q549J7

Explore the universe of human proteins at neXtProt for ITGB1BP2: NX_Q9UKP3

Explore proteomics data for ITGB1BP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ITGB1BP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036410.1  
    ENSEMBL proteins: 
     ENSP00000362935   ENSP00000440289  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR007051 CHORD
     IPR008978 HSP20-like_chaperone
     IPR007052 CS_dom

    Graphical View of Domain Structure for InterPro Entry Q9UKP3

    ProtoNet protein and cluster: Q9UKP3

    1 Blocks protein domain: IPB007052 CS domain

    UniProtKB/Swiss-Prot: ITBP2_HUMAN, Q9UKP3
    Domain: The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The
    presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and
    the tail domain but prevents the binding of the full-length protein
    Similarity: Contains 2 CHORD domains
    Similarity: Contains 1 CS domain


    Find genes that share domains with ITGB1BP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ITBP2_HUMAN, Q9UKP3
    Function: May play a role during maturation and/or organization of muscles cells

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005178integrin binding IEA--
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0017124SH3 domain binding IEA--
         
    Find genes that share ontologies with ITGB1BP2           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Itgb1bp2):
     cardiovascular system  homeostasis/metabolism  mortality/aging 

    Find genes that share phenotypes with ITGB1BP2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ITGB1BP2
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    hsa-miR-375 hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmidITGB1BP2 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    extracellular1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030018Z disc IEA--

    Find genes that share ontologies with ITGB1BP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ITGB1BP2
    Interactions:

        Search GeneGlobe Interaction Network for ITGB1BP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for ITGB1BP2 (Q9UKP33 ENSP000003629354) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ECDO959053, ENSP000004015664I2D: score=1 STRING: ENSP00000401566
    SUGT1Q9Y2Z03, ENSP000003672084I2D: score=1 STRING: ENSP00000367208
    HSP90AA1P079003, ENSP000003351534I2D: score=3 STRING: ENSP00000335153
    RARAP102763I2D: score=3 
    RARGP136313I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS10506186
    GO:0007517muscle organ development TAS10506186

    Find genes that share ontologies with ITGB1BP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ITGB1BP2 (ITBP2)

    1 HMDB Compound for ITGB1BP2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 Novoseek inferred chemical compound relationship for ITGB1BP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 0 2 10506186 (1), 12965203 (1)



    Find genes that share compounds with ITGB1BP2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ITGB1BP2 gene: 
    NM_012278.1  

    Unigene Cluster for ITGB1BP2:

    Integrin beta 1 binding protein (melusin) 2
    Hs.109999  [show with all ESTs]
    Unigene Representative Sequence: BM808220
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373829(uc004dzr.1) ENST00000483897 ENST00000465388 ENST00000475413
    ENST00000538820(uc004dzs.1)
    miRNA
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    hsa-miR-375 hsa-miR-4273
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      QuantiTect SYBR Green Assays in human, mouse, rat ITGB1BP2
      QuantiFast Probe-based Assays in human, mouse, rat ITGB1BP2

    Additional mRNA sequence: 

    AF110225.1 AF140690.1 BC108901.2 

    5 DOTS entries:

    DT.111073  DT.111074  DT.121299531  DT.40267729  DT.95126884 

    Selected AceView cDNA sequences (see all 30):

    NM_012278 AI052173 BX282304 AI568769 AA336372 AF140690 BP372847 AF110225 
    AA313760 W92190 AW293640 AW270091 AI198447 AA134809 AA971480 AA134808 
    AA216041 AI291780 BI915214 AA249107 F25233 W94887 F35717 AA249829 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ITGB1BP2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b
    SP1:                                            -           -                       -     -               
    SP2:                                            -           -                       -     -               
    SP3:                                                                                                      
    SP4:                                                                                                      


    ECgene alternative splicing isoforms for ITGB1BP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ITGB1BP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTTTTTTT
    ITGB1BP2 Expression
    About this image


    ITGB1BP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 7 entries
             Interzone Cells Stylopod Synovial Joint
             Zeugopod
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod Long Bone
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Interzone Cells Stylopod Synovial Joint
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
    ITGB1BP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ITGB1BP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.109999

    UniProtKB/Swiss-Prot: ITBP2_HUMAN, Q9UKP3
    Tissue specificity: Expressed in skeletal and cardiac muscles but not in other tissues

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ITGB1BP2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Itgb1bp21 , 5 integrin beta 1 binding protein 21, 5 91.04(n)1
    93.64(a)1
      X (44.17 cM)5
    265491  NM_013712.21  NP_038740.11 
     1014490885 
    chicken
    (Gallus gallus)
    Aves ITGB1BP21 integrin beta 1 binding protein (melusin) 2 61.98(n)
    59.15(a)
      422208  XM_420200.4  XP_420200.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    48(a)
    47(a)
    many → 1
    many → 1
    AAWZ02039611(2733-4888)
    GL343599.1(76207-104721)
    zebrafish
    (Danio rerio)
    Actinopterygii ITGB1BP26
    integrin beta 1 binding protein (melusin) 2
    43(a)
    1 ↔ 1
    7(24894860-24913075) ENSDARG00000030176
    fruit fly
    (Drosophila melanogaster)
    Insecta CHORD3 zinc ion binding 41(a)   95E8   --
    worm
    (Caenorhabditis elegans)
    Secernentea chp-13   -- 33(a)   I(5103811-5104915)   --


    ENSEMBL Gene Tree for ITGB1BP2 (if available)
    TreeFam Gene Tree for ITGB1BP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ITGB1BP2 gene
    CHORDC12  
    1 SIMAP similar gene for ITGB1BP2 using alignment to 2 protein entries:     ITBP2_HUMAN (see all proteins):
    CHORDC1

    Find genes that share paralogs with ITGB1BP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ITGB1BP2 (see all 83)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1505751411,2
    C--70521634(+) TTTCAA/GTAATC 1 -- ut510--------
    rs1999683961,2
    C--70521644(+) CATTCA/GACCAA 1 -- ut510--------
    rs1382043461,2
    C--70521693(+) GGCAGC/TACTTT 2 H Y mis10--------
    rs1865578421,2
    --70521886(+) ACATTA/GTATGG 1 -- int10--------
    rs1914101781,2
    --70521904(+) CCATAA/CATAGA 1 -- int10--------
    rs1428828121,2
    C--70522084(+) AGAGAG/TAATAC 1 -- int10--------
    rs2019232661,2
    --70522123(+) TGTTAC/TCAGGG 1 -- int10--------
    rs1837431761,2
    C--70522217(+) CCCCAA/GTAGAA 1 -- int10--------
    rs1493889461,2
    C,F--70522322(+) AGGCCC/TTGCTA 2 P L mis11Minor allele frequency- T:0.00NA 4416
    rs1160579381,2
    C--70522417(+) GAGGAG/TGAGGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for ITGB1BP2 (70521584 - 70525221 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ITGB1BP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv33082CNV Loss17666407
    esv1584074OTHER Inversion17803354

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ITGB1BP2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300332    OMIM disorders: --


    Find genes that share disorders with ITGB1BP2           About GenesLikeMe

    2 Novoseek inferred disease relationships for ITGB1BP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cardiac hypertrophy 54.4 2 12965203 (1), 17468044 (1)
    hypertrophy 47 3 20017903 (1), 18474241 (1), 17468044 (1)

    Genetic Association Database (GAD): ITGB1BP2
    Human Genome Epidemiology (HuGE) Navigator: ITGB1BP2 (1 document)

    Export disorders for ITGB1BP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ITGB1BP2 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with ITGB1BP2)
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    1. Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. (PubMed id 10506186)1, 2, 3, 9 Brancaccio M.... Silengo L. (J. Biol. Chem. 1999)
    2. Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients. (PubMed id 20017903)1, 4, 9 Palumbo V....Crovella S. (BMC Med. Genet. 2009)
    3. Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy. (PubMed id 23124043)1 Ruppert V....Pankuweit S. (Gene 2013)
    4. Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1. (PubMed id 23184943)1 Hong T.J....Hahn J.S. (J. Biol. Chem. 2013)
    5. Altered melusin pathways involved in cardiac remodeling following acute myocardial infarction. (PubMed id 21546274)1 Gu R....Xu B. (Cardiovasc. Pathol. 2012)
    6. Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. (PubMed id 15604093)1 Albers M....Koegl M. (amp 2005)
    7. Sensing heart stress. (PubMed id 12514714)1 Barki-Harrington L. and Rockman H.A. (Nat. Med. 2003)
    8. The selective regulation of alpha Vbeta 1 integrin expression is based on the hierarchical formation of alpha V-containing heterodimers. (PubMed id 11997396)1 Koistinen P. and Heino J. (J. Biol. Chem. 2002)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells. (PubMed id 9388239)1 Yan Z....Friedman E. (J. Biol. Chem. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26548 HGNC: 6154 AceView: ITGB1BP2 Ensembl:ENSG00000147166 euGenes: HUgn26548
    ECgene: ITGB1BP2 H-InvDB: ITGB1BP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ITGB1BP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ITGB1BP2 gene:
    Search GeneIP for patents involving ITGB1BP2

    GeneCards and IP:
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