Aliases for ITGA9 Gene
External Ids for ITGA9 Gene
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
GeneCards Summary for ITGA9 Gene
ITGA9 (Integrin, Alpha 9) is a Protein Coding gene. Diseases associated with ITGA9 include congenital muscular dystrophy with hyperlaxity. Among its related pathways are PI3K-Akt signaling pathway and Regulation of actin cytoskeleton. An important paralog of this gene is ITGA8.
UniProtKB/Swiss-Prot for ITGA9 Gene
Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin.