External Ids for ITGA10 Gene
Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
GeneCards Summary for ITGA10 Gene
ITGA10 (Integrin, Alpha 10) is a Protein Coding gene. Diseases associated with ITGA10 include arrhythmogenic right ventricular cardiomyopathy. Among its related pathways are PI3K-Akt signaling pathway and Regulation of actin cytoskeleton. GO annotations related to this gene include collagen binding. An important paralog of this gene is ITGA8.
UniProtKB/Swiss-Prot for ITGA10 Gene
Integrin alpha-10/beta-1 is a receptor for collagen