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ITGA1 Gene

protein-coding GIFtS: 56

GC05P052119

integrin, alpha 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CD49a ^¹, ²
VLA-1 ^³
VLA1 ^¹, ², ⁵

Descriptions
CD49 antigen-like family member A ^³
CD49a antigen ^³
Laminin and collagen receptor ^², ³
integrin, alpha 1 ^²
very late activation protein 1 ^²

External Ids
HGNC: 6134¹
Entrez Gene: 3672²
UniProtKB: P56199³
Ensembl: ENSG00000213949⁷

Search outside databases for aliases for ITGA1 gene

Previous GC identifers: GC05P052249 GC05U900017 GC05P052099

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ITGA1:

This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the

beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric

receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The

alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to

be involved in collagen binding. [provided by RefSeq]

UniProtKB/Swiss-Prot: ITA1_HUMAN, P56199

Function: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the

proline-hydroxylated sequence G-F-P-G-E-R in collagen

Gene Wiki entry for ITGA1 (CD49a)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ITGA1 gene

Entrez Gene cytogenetic band: 5q11.2 Ensembl cytogenetic band: 5q11.2 HGNC cytogenetic band: 5q11.1

ITGA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P052119: (about GC identifiers)

Start:	52,119,893 bp from pter
End:	52,285,242 bp from pter
Size:	165,350 bases
Orientation:	plus strand

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ITA1_HUMAN, P56199 (See protein sequence)

Recommended Name: Integrin alpha-1 precursor

Size: 1179 amino acids; 130848 Da

Subunit: Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1. Interacts with

RAB21

Subcellular location: Membrane; Single-pass type I membrane protein

PDB structures from and Proteopedia :

1PT6 (3D)

1QC5 (3D)

1QCY (3D)

Secondary accessions: B2RNU0

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_852478.1

ENSEMBL proteins:

ENSP00000282588

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant ITGA1 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Integrin alpha 1, Integrin alpha 1 + beta 1)
	Human Recombinant Proteins from Abnova (ITGA1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008305	integrin complex	TAS	8428973
GO:0009897	external side of plasma membrane	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for ITGA1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of ITGA1
	Sigma-Aldrich Antibodies for ITGA1
	R&D Systems Antibodies for ITGA1 (Integrin alpha 1/CD49a)
	Antibodies from Abcam (Integrin alpha 1, Integrin alpha 1 + beta 1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ITGA1)
	Novus Biologicals Antibodies for ITGA1

Assays for ITGA1:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of ITGA1
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P56199

ProtoNet protein and cluster: P56199

4 Blocks protein families:

IPB000413 Integrins alpha chain

IPB002035 Von Willebrand factor type A domain signature

IPB013513 Integrin alpha chain

IPB013517 FG-GAP

UniProtKB/Swiss-Prot: ITA1_HUMAN, P56199

Domain: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo

protease cleavage

Similarity: Belongs to the integrin alpha chain family

Similarity: Contains 7 FG-GAP repeats

Similarity: Contains 1 VWFA domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ITGA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ITGA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181501

Applied Biosystems Silencer® siRNAs for ITGA1

Sigma-Aldrich siRNA and siRNA Panels for ITGA1

Sigma-Aldrich shRNA Panels and shRNA for ITGA1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_181501
Myc/DDK tagged cDNA clone in CMV expression vector: NM_181501
untagged cDNA clones in CMV expression vector (see all 2): NM_181501

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_181501

UniProtKB/Swiss-Prot: ITA1_HUMAN, P56199

Function: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the

proline-hydroxylated sequence G-F-P-G-E-R in collagen

Genatlas biochemistry entry for ITGA1:

integrin,alpha 1,cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or

to other cells,through hetero dimerization and connecting to the cytoskeleton and various

signaling molecules within cells,dimerizing with ITGB1 in collagen,laminin receptors

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Itga1):

homeostasis/metabolism

immune system

renal/urinary system

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0005509	calcium ion binding	IEA	--
GO:0005518	collagen binding	TAS	8428973

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/6 Sigma-Aldrich "Your Favorite Gene" Pathways for ITGA1 (Your Favorite Gene powered by Ingenuity) (see all 6 )

Reelin Signaling in Neurons
Caveolar-mediated Endocytosis
NF-&kappa
Integrin Signaling
Agrin Interactions at Neuromuscular Junction

GeneDecks ITGA1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for ITGA1

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	IEA	--
GO:0007160	cell-matrix adhesion	NAS	--
GO:0007229	integrin-mediated signaling pathway	IEA	--
GO:0030593	neutrophil chemotaxis	IEA	--
GO:0045123	cellular extravasation	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ITGA1
7 Novoseek chemical compound relationships for ITGA1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
matrigel	39.41	1	18775695 (1)
wortmannin	9.98	1	16289050 (1)
oxygen	0.00	1	16807282 (1)
lysine	0.00	1	11336656 (1)
progesterone	0.00	2	9009235 (1)
magnesium	0.00	2	2380249 (1), 10457223 (1)
tyrosine	0.00	2	11336656 (1), 16472776 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ITGA1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ITGA1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181501

Sigma-Aldrich siRNA and siRNA Panels for ITGA1

Sigma-Aldrich shRNA Panels and shRNA for ITGA1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_181501

REFSEQ mRNAs for ITGA1 gene:

NM_181501.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_181501

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_181501
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_181501
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_181501

24/542 AceView cDNA sequences (see all 542 ):

AI074570 BM788674 BQ058833 AI383957 R50724 AI378348 AL709969 BG619261

BX400814 AI972404 AA327614 CR604356 BP340360 AI580785 CR613377 AA151209

CR617340 AW172842 BE384077 BM453706 BQ056155 AI333101 CR603721 CR590680

highest scoring ESTs for ITGA1:

AL079983 AA043378 AA151209 AA960848 AI580785 AI769211 AI911294 BI836076 H97558 BP422985

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000282588

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ITGA1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ITGA1

¹ / ² / ³

8 probe-sets matching ITGA1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
120_at²^{, 3}	U95-A	1	1.00	1.00	0.99	1.06	X68742	0.40	0.50	0.45	1
37484_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.83	X68742	0.40	0.50	0.45	1
45200_at*²^{, 3}	U95-B	1	0.94	1.00	0.98	0.95	AL079983	0.80	0.70	0.75	1
44710_at*²^{, 3}	U95-B	1	0.69	1.00	0.93	1.19	AA203623	0.40	0.50	0.45	1
226731_at*²^{, 3}	U133-B	1	1.00	1.00	--	--	AA156873	0.20	0.25	0.23	2
214660_at*²^{, 3}	U133-A	1	1.00	1.00	--	--	X68742	0.40	0.50	0.45	1
226731_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
214660_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ITGA1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --
Expression variation in blood from EXPOLDB for ITGA1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ITGA1 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ITGA1¹	--	integrin, alpha 1	91.48(n) 92.14(a)	489210 XM_546328.2 XP_546328.2
chimpanzee (Pan troglodytes)	ITGA1¹	--	integrin, alpha 1	99.72(n) 99.58(a)	461880 XM_517769.2 XP_517769.2
cow (Bos taurus)	ITGA1¹	--	integrin, alpha 1	90.17(n) 91.38(a)	535951 XM_616068.3 XP_616068.3
rat (Rattus norvegicus)	Itga1¹	--	integrin alpha 1	85.09(n) 87.86(a)	25118 NM_030994.1 NP_112256.1
mouse (Mus musculus)	Itga1^{1, 5}	13 (65.00 cM)⁵	integrin alpha 1^{1, 5}	84.72(n)¹ 87.95(a)¹	109700¹ NM_001033228.2¹ NP_001028400.1¹ AI593010⁵ AK029105⁵ (see all 16)

About this table Species with no ortholog for ITGA1

ENSEMBL Gene Tree for ITGA1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ITGA1 gene

ITGA11² ITGA2² ITGA10²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1008 NCBI SNPs in ITGA1 are shown (see all 1008 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 470)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1047481^1,2	A,C,F,H,O	52285233(+)	`AACAGA/GAAGAT`	1	--	ut3¹		9	MN EU EA WA	1020
	rs988574^1,2	C,F,H,O	52276567(+)	`GGGAGA/GACTTC`	1	E/G	mis¹		9	MN EA NA EU WA	2236
--	rs6895049^1,2	A,C,F,H	52284630(+)	`CTCCCT/GGCCCA`	1	--	ut3¹		4	EU EA WA	412
	rs6890588^1,2	A,C,F,H	52284661(+)	`AATTGA/GGCTAA`	1	--	ut3¹		4	EU EA WA	412
	rs2279587^1,2	C,F,H,O	52250338(-)	`TTTAAC/TTACGG`	1	V/I	mis¹		15	NA EU EA WA	1398
	rs3088365^1,2	A,C,F,H	52284983(-)	`AACTCT/CTTCTT`	1	--	ut3¹		9	MN EU EA WA	1022
	rs1047483^1,2	A,C,F,H	52285369(+)	`GCTGCA/TTGTGT`	1	--	ng3¹		5	MN EU EA WA	596
	rs3088364^1,2	A,C,F	52284785(-)	`AAAAGG/AGTTTT`	1	--	ut3¹		1	MN	184
	rs3088363^1,2	A,C,F	52284812(-)	`AAACTG/ACTTTA`	1	--	ut3¹		1	MN	184
	rs4145748^1,2	C,F,H	52237479(+)	`CCAGAC/TGCTCA`	1	T/M	mis¹		11	EU EA WA NA	976

About this table

HapMap Linkage Disequilibrium images for ITGA1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 192968

10/12 Novoseek disease relationships for ITGA1 gene (see all 12 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
preeclampsia	19.71	1	9403732 (1)
tumors	19.64	9	17982677 (1), 1711920 (1), 8864174 (1), 18579572 (1) (see all 6)
necrosis	15.97	1	1869591 (1)
metastasis	15.42	4	8105045 (3), 15679046 (1)
psoriasis	9.04	4	18269595 (3), 17603494 (1)
hepatocellular carcinoma	8.83	2	9824613 (2)
colitis	0.12	2	2341567 (2)
melanoma	0.00	7	8105045 (4), 9464621 (1)
cancer	0.00	1	17982677 (1)
influenza	0.00	3	17372009 (2)

About this table

Genetic Association Database: ITGA1
Human Genome Epidemiology Navigator: ITGA1 (7 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/189 PubMed articles for ITGA1 gene (see all 189 ):

Expression of native and truncated forms of the human integrin alpha 1 subunit. (PubMed id 8428973)^{2, 3, 4} Briesewitz R.... Marcantonio E.E. (1993)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{3, 4} Liu T.... Smith R.D. (2005)
Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1. (PubMed id 14660600)^{3, 4} Nymalm Y....Salminen T.A. (2004)
Platelet GPIaC807T polymorphism is associated with negative outcome of sudden hearing loss. (PubMed id 15109703)^{3, 6} Rudack C....Junker R. (2004)
The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)^{3, 4} Schmutz J.... Rubin E.M. (2004)
Antiphospholid antibodies regulate the expression of trophoblast cell adhesion molecules. (PubMed id 11937138)^{2, 3} Di Simone N....Caruso A. (2002)
Platelet hyperreactivity after coronary artery bypass grafting: the possible relevance to glycoprotein polymorphisms. A preliminary report. (PubMed id 11454259)^{3, 6} Golanski J....Watala C. (2001)
[Study of C807T polymorphism of the platelet collagen receptor alpha2 gene coding sequence in Suzhou Han population] (PubMed id 11877061)^{3, 6} Shi J....Ruan C. (2001)
Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM. (PubMed id 10455165)^{3, 4} Rich R.L.... Hook M. (1999)
Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion. (PubMed id 17982677)^{1, 3} Van Slambrouck S....Steelant W.F. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 3672	HGNC: 6134	AceView: PELO	Ensembl:ENSG00000213949	euGenes: HUgn3672
ECgene: ITGA1	H-InvDB: ITGA1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ITGA1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ITGA1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ITGA1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ITGA1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ITGA1		Antibodies for ITGA1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ITGA1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ITGA1)
	Antibodies (ITGA1)
	Chimera RNAi (ITGA1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (Integrin alpha 1, Integrin alpha 1 + beta 1)

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Search Tocris compounds for ITGA1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ITGA1

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ITGA1 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for ITGA1

Summaries
for ITGA1

Genomic Location
for ITGA1

Proteins
for ITGA1

Protein Domains/
Families
for ITGA1

Gene Function
for ITGA1

Pathways & Interactions
for ITGA1

Drugs & Compounds
for ITGA1

Transcripts
for ITGA1

Expression
for ITGA1

Orthologs
for ITGA1

Paralogs
for ITGA1

SNPs/Variants
for ITGA1

Disorders & Mutations
for ITGA1

Medical News
for ITGA1

Publications
for ITGA1

Search for ITGA1

Genome Databases showing ITGA1

Other Databases showing ITGA1

Specialized Databases showing ITGA1

Licensable Technologies
for ITGA1

Services
for ITGA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ITGA1 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor ITGA1

Summariesfor ITGA1

Genomic Locationfor ITGA1

Proteinsfor ITGA1

Protein Domains/Familiesfor ITGA1

Gene Functionfor ITGA1

Pathways & Interactionsfor ITGA1

Drugs & Compoundsfor ITGA1

Transcriptsfor ITGA1

Expression for ITGA1

Orthologsfor ITGA1

Paralogsfor ITGA1

SNPs/Variantsfor ITGA1

Disorders & Mutationsfor ITGA1

Medical Newsfor ITGA1

Publicationsfor ITGA1

Search for ITGA1

Genome Databases showing ITGA1

Other Databases showing ITGA1

Specialized Databases showing ITGA1

Licensable Technologiesfor ITGA1

Servicesfor ITGA1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ITGA1

Summaries
for ITGA1

Genomic Location
for ITGA1

Proteins
for ITGA1

Protein Domains/
Families
for ITGA1

Gene Function
for ITGA1

Pathways & Interactions
for ITGA1

Drugs & Compounds
for ITGA1

Transcripts
for ITGA1

Expression
for ITGA1

Orthologs
for ITGA1

Paralogs
for ITGA1

SNPs/Variants
for ITGA1

Disorders & Mutations
for ITGA1

Medical News
for ITGA1

Publications
for ITGA1

Licensable Technologies
for ITGA1

Services
for ITGA1