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ITFG3 Gene

protein-coding   GIFtS: 49
GCID: GC16P000305

Integrin Alpha FG-GAP Repeat Containing 3

(Previous name: chromosome 16 open reading frame 9)
(Previous symbol: C16orf9)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Integrin Alpha FG-GAP Repeat Containing 31 2
C16orf91 2 3
Chromosome 16 Open Reading Frame 91
gs192
Protein ITFG32

External Ids:    HGNC: 141631   Entrez Gene: 839862   Ensembl: ENSG000001679307   UniProtKB: Q9H0X43   

Export aliases for ITFG3 gene to outside databases

Previous GC identifers: GC16P000228 GC16P000231 GC16P000238 GC16P000240 GC16P000285 GC16P000204 GC16P000286 GC16P000287 GC16P000288 GC16P000289 GC16P000290 GC16P000294


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ITFG3 Gene:
ITFG3 (integrin alpha FG-GAP repeat containing 3) is a protein-coding gene. Diseases associated with ITFG3 include prostate cancer, and prostatitis. An important paralog of this gene is KIAA1467.

Gene Wiki entry for ITFG3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010393.17  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ITFG3 gene promoter:
         AML1a   SREBP-1c   Lmo2   CUTL1   SREBP-1b   MEF-2A   SREBP-1a   COMP1   aMEF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITFG3 promoter sequence
   Search Chromatin IP Primers for ITFG3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ITFG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ITFG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITFG3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P000305:  view genomic region     (about GC identifiers)

Start:
284,545 bp from pter      End:
319,942 bp from pter
Size:
35,398 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ITFG3_HUMAN, Q9H0X4 (See protein sequence)
Recommended Name: Protein ITFG3  
Size: 552 amino acids; 59660 Da
Sequence caution: Sequence=AAK61220.1; Type=Erroneous gene model prediction;
Secondary accessions: D3DU45 Q7L416 Q96FR1 Q96MC7 Q96S30
Alternative splicing: 2 isoforms:  Q9H0X4-1   Q9H0X4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ITFG3: NX_Q9H0X4

Explore proteomics data for ITFG3 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn116, Asn120, Asn314, Asn389, Asn473
  • Modification sites at PhosphoSitePlus

  • See ITFG3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001271426.1  NP_114428.1  

    ENSEMBL proteins: 
     ENSP00000382814   ENSP00000301679   ENSP00000388726   ENSP00000392612   ENSP00000402119  
     ENSP00000395334   ENSP00000399150   ENSP00000407669   ENSP00000398433   ENSP00000301678  
     ENSP00000409309   ENSP00000405659   ENSP00000412581   ENSP00000407875   ENSP00000397477  
     ENSP00000411394  

    ITFG3 Human Recombinant Protein Products:

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    Novus Biologicals ITFG3 Protein
    Novus Biologicals ITFG3 Lysates
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    Cloud-Clone Corp. Proteins for ITFG3

    ITFG3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    ThermoFisher Antibodies for ITFG3
    LSBio Antibodies in human, mouse, rat for ITFG3

    ITFG3 Assay Products:

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    Cloud-Clone Corp. ELISAs for ITFG3
    Cloud-Clone Corp. CLIAs for ITFG3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR011047 Quinonprotein_ADH-like_supfam

    Graphical View of Domain Structure for InterPro Entry Q9H0X4

    ProtoNet protein and cluster: Q9H0X4

    UniProtKB/Swiss-Prot: ITFG3_HUMAN, Q9H0X4
    Similarity: Belongs to the ITFG3 family


    ITFG3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    ITFG3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ITFG3:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ITFG3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ITFG3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ITFG3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ITFG3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ITFG3:
    hsa-mir-24-3p (MIRT030576), hsa-mir-320a (MIRT044831), hsa-mir-320b (MIRT036242)

    Block miRNA regulation of human, mouse, rat ITFG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ITFG3 (see all 17):
    hsa-miR-148b hsa-miR-301a hsa-miR-124 hsa-miR-199b-5p hsa-miR-506 hsa-miR-130b hsa-miR-148a hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmidITFG3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ITFG3
    Predesigned siRNA for gene silencing in human, mouse, rat ITFG3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ITFG3

    Clone
    Products:
         
    OriGene clones in human, mouse for ITFG3 (see all 7)
    OriGene ORF clones in mouse, rat for ITFG3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITFG3 (NM_032039)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITFG3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITFG3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ITFG3
    Browse ESI BIO Cell Lines and PureStem Progenitors for ITFG3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITFG3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ITFG3_HUMAN, Q9H0X4: Membrane; Single-pass type II membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009986cell surface IDA19349973
    GO:0016021integral component of membrane IEA--
    GO:0070062extracellular vesicular exosome IDA--

    ITFG3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ITFG3
    Interactions:

        Search GeneGlobe Interaction Network for ITFG3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for ITFG3 (Q9H0X43 ENSP000003016784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MMEP084733I2D: score=2 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    ITFG3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ITFG3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ITFG3 gene (2 alternative transcripts): 
    NM_001284497.1  NM_032039.3  

    Unigene Cluster for ITFG3:

    Integrin alpha FG-GAP repeat containing 3
    Hs.513225  [show with all ESTs]
    Unigene Representative Sequence: NM_032039
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000399932(uc002cgf.3) ENST00000301679(uc010bqr.2 uc002cgg.2)
    ENST00000419173 ENST00000426695 ENST00000438220 ENST00000447499 ENST00000453430
    ENST00000449945 ENST00000420046 ENST00000301678(uc002cgh.3) ENST00000420500
    ENST00000417499 ENST00000496874 ENST00000421000 ENST00000468354 ENST00000424016
    ENST00000442458(uc010uud.1) ENST00000450082
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ITFG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ITFG3 (see all 17):
    hsa-miR-148b hsa-miR-301a hsa-miR-124 hsa-miR-199b-5p hsa-miR-506 hsa-miR-130b hsa-miR-148a hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmidITFG3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ITFG3
    Predesigned siRNA for gene silencing in human, mouse, rat ITFG3
    Clone
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    OriGene clones in human, mouse for ITFG3 (see all 7)
    OriGene ORF clones in mouse, rat for ITFG3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITFG3 (NM_032039)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITFG3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITFG3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ITFG3
    OriGene qSTAR qPCR primer pairs in human, mouse for ITFG3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ITFG3
      QuantiTect SYBR Green Assays in human, mouse, rat ITFG3
      QuantiFast Probe-based Assays in human, mouse, rat ITFG3

    Additional mRNA sequence: 

    AK057165.1 AK310766.1 AL136542.1 BC009214.2 BC010521.1 BC013047.1 BC032112.2 

    16 DOTS entries:

    DT.115841  DT.100800352  DT.100800351  DT.445954  DT.95228685  DT.120711782  DT.40195130  DT.95228615 
    DT.100029083  DT.100800346  DT.120711829  DT.92463509  DT.95228613  DT.100650579  DT.101978513  DT.91659641 

    Selected AceView cDNA sequences (see all 329):

    BG831800 BM977599 CD676377 BU190879 AA319239 BM556126 BM473030 AI669123 
    BM783406 AI285054 BQ709032 BQ224878 BX362805 CB988951 BF527932 AW440715 
    AI372554 BU845993 BC013047 AA337220 AA987852 BM453908 AW732415 BM925289 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ITFG3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ITFG3 Expression
    About this image


    ITFG3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter
     
     Adipose (Muscoskeletal System)
     
     Esophagus (Gastrointestinal Tract)
     
     Gall Bladder (Hepatobiliary System)
     
     Placenta (Extraembryonic Tissues)
    ITFG3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ITFG3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513225
        Custom PCR Arrays for ITFG3
    Primer
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    OriGene qPCR primer pairs and template standards for ITFG3
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    QuantiFast Probe-based Assays in human, mouse, rat ITFG3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITFG3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ITFG3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Itfg31 , 5 integrin alpha FG-GAP repeat containing 31, 5 77.62(n)1
    73.68(a)1
      17 (13.07 cM)5
    1065811  NM_001206335.11  NP_001193264.11 
     262118225 
    chicken
    (Gallus gallus)
    Aves ITFG31 integrin alpha FG-GAP repeat containing 3 57.72(n)
    46.14(a)
      416653  XM_414950.4  XP_414950.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    35(a)
    1 → many
    GL343507.1(529461-543019)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia itfg31 integrin alpha FG-GAP repeat containing 3 52.42(n)
    42.08(a)
      100158638  NM_001128045.1  NP_001121517.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7964391 protein ITFG3-like 46.56(n)
    33.4(a)
      796439  XM_001336732.4  XP_001336768.2 


    ENSEMBL Gene Tree for ITFG3 (if available)
    TreeFam Gene Tree for ITFG3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ITFG3 gene
    KIAA14672  ENSG000002698812  

    ITFG3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ITFG3 (see all 1035)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs727658081,2
    C--282882(+) AGGCCG/AGGAGT 1 -- us2k15Minor allele frequency- A:0.32NA WA EA 362
    rs727658091,2
    C--282890(+) AGTGGT/CCTATT 1 -- us2k15Minor allele frequency- C:0.37NA WA EA 362
    rs1151155721,2
    F--282902(+) TGACAC/TTCCAC 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs785855111,2
    C--283127(+) CCCAGC/GCTGGA 1 -- us2k10--------
    rs124470371,2
    H--283207(+) ctcccA/Gagtag 1 -- us2k10--------
    rs606916791,2
    C--283227(+) TAGGCA/GCCCGT 1 -- us2k12Minor allele frequency- G:0.33NA CSA 3
    rs12039721,2
    C,H--283232(-) tggtgG/Acgggc 1 -- us2k15Minor allele frequency- A:0.07MN NA CSA 191
    rs1491655221,2
    --283244(+) GCCTGG/TCTAAT 1 -- us2k10--------
    rs1926596551,2
    --283273(+) GAGACG/TGGGTT 1 -- us2k10--------
    rs1454091981,2
    C--283304(+) GTCTAA/GATTTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ITFG3 (284545 - 319942 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ITFG3 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2667528CNV Deletion23128226
    esv2660459CNV Deletion23128226
    esv2422427CNV Duplication17116639
    esv1473294CNV Insertion17803354
    nsv904674CNV Loss21882294
    dgv2465n71CNV Loss21882294
    dgv2458n71CNV Loss21882294
    dgv32n68CNV Loss17160897
    dgv2467n71CNV Loss21882294
    nsv518291CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ITFG3
    DNA2.0 Custom Variant and Variant Library Synthesis for ITFG3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for ITFG3:    
    About MalaCards
    prostate cancer    prostatitis


    ITFG3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ITFG3
    Human Genome Epidemiology (HuGE) Navigator: ITFG3 (2 documents)

    Export disorders for ITFG3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ITFG3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with ITFG3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (PubMed id 19862010)1, 4 Ganesh S.K....Lin J.P. (Nat. Genet. 2009)
    3. Mass-spectrometric identification and relative quantification of N- linked cell surface glycoproteins. (PubMed id 19349973)1, 2 Wollscheid B.... Watts J.D. (Nat. Biotechnol. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    7. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (Hum. Mol. Genet. 2001)
    8. Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. (PubMed id 23696099)1 Ding K....Kullo I.J. (G3 (Bethesda) 2013)
    9. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. (PubMed id 23446634)1 Chen Z....Reiner A.P. (Hum. Mol. Genet. 2013)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83986 HGNC: 14163 AceView: DKFZP761D0211 Ensembl:ENSG00000167930 euGenes: HUgn83986
    ECgene: ITFG3 H-InvDB: ITFG3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ITFG3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ITFG3 gene:
    Search GeneIP for patents involving ITFG3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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