Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ITFG3 Gene

Aliases for ITFG3 Gene

  • Integrin Alpha FG-GAP Repeat Containing 3 2 3
  • C16orf9 3 4
  • Chromosome 16 Open Reading Frame 9 2
  • Protein ITFG3 3
  • Gs19 3

External Ids for ITFG3 Gene

Previous Symbols for ITFG3 Gene

  • C16orf9

Summaries for ITFG3 Gene

GeneCards Summary for ITFG3 Gene

ITFG3 (Integrin Alpha FG-GAP Repeat Containing 3) is a Protein Coding gene. An important paralog of this gene is KIAA1467.

Gene Wiki entry for ITFG3 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ITFG3 Gene

Genomics for ITFG3 Gene

Genomic Location for ITFG3 Gene

Start:
234,546 bp from pter
End:
269,943 bp from pter
Size:
35,398 bases
Orientation:
Plus strand

Genomic View for ITFG3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ITFG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ITFG3 Gene

Regulatory Elements for ITFG3 Gene

Proteins for ITFG3 Gene

  • Protein details for ITFG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0X4-ITFG3_HUMAN
    Recommended name:
    Protein ITFG3
    Protein Accession:
    Q9H0X4
    Secondary Accessions:
    • D3DU45
    • Q7L416
    • Q96FR1
    • Q96MC7
    • Q96S30

    Protein attributes for ITFG3 Gene

    Size:
    552 amino acids
    Molecular mass:
    59660 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK61220.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ITFG3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ITFG3 Gene

Proteomics data for ITFG3 Gene at MOPED

Post-translational modifications for ITFG3 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn116, Asn120, Asn314, Asn389, and Asn473

No data available for DME Specific Peptides for ITFG3 Gene

Domains for ITFG3 Gene

Protein Domains for ITFG3 Gene

UniProtKB/Swiss-Prot:

ITFG3_HUMAN
Family:
  • Belongs to the ITFG3 family.:
    • Q9H0X4
genes like me logo Genes that share domains with ITFG3: view

No data available for Gene Families for ITFG3 Gene

Function for ITFG3 Gene

Gene Ontology (GO) - Molecular Function for ITFG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with ITFG3: view

Phenotypes for ITFG3 Gene

GenomeRNAi human phenotypes for ITFG3:
genes like me logo Genes that share phenotypes with ITFG3: view

miRNA for ITFG3 Gene

miRTarBase miRNAs that target ITFG3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ITFG3 Gene

Localization for ITFG3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ITFG3 Gene

Membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ITFG3 Gene COMPARTMENTS Subcellular localization image for ITFG3 gene
Compartment Confidence
plasma membrane 3
cytosol 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ITFG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009986 cell surface IDA 19349973
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 20458337
genes like me logo Genes that share ontologies with ITFG3: view

Pathways for ITFG3 Gene

SuperPathways for ITFG3 Gene

No Data Available

Interacting Proteins for ITFG3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000301678%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q9H0X4-ITFG3_HUMAN ENSP00000301678 for ITFG3 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for ITFG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ITFG3: view

No data available for Pathways by source for ITFG3 Gene

Transcripts for ITFG3 Gene

Unigene Clusters for ITFG3 Gene

Integrin alpha FG-GAP repeat containing 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ITFG3 Gene

No ASD Table

Relevant External Links for ITFG3 Gene

GeneLoc Exon Structure for
ITFG3
ECgene alternative splicing isoforms for
ITFG3

Expression for ITFG3 Gene

mRNA expression in normal human tissues for ITFG3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ITFG3 Gene

SOURCE GeneReport for Unigene cluster for ITFG3 Gene Hs.513225

genes like me logo Genes that share expressions with ITFG3: view

Orthologs for ITFG3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ITFG3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 97 (a)
OneToMany
ITFG3 36
  • 97.95 (n)
  • 97.46 (a)
cow
(Bos Taurus)
Mammalia ITFG3 36
  • 75.32 (n)
  • 68.6 (a)
ITFG3 37
  • 68 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 71 (a)
OneToMany
ITFG3 36
  • 77.37 (n)
  • 71.69 (a)
mouse
(Mus musculus)
Mammalia Itfg3 36
  • 77.62 (n)
  • 73.68 (a)
Itfg3 16
Itfg3 37
  • 73 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 48 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 45 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Itfg3 36
  • 77.11 (n)
  • 72.46 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 44 (a)
ManyToMany
-- 37
  • 51 (a)
ManyToMany
-- 37
  • 45 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
ITFG3 36
  • 57.72 (n)
  • 46.14 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 35 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia itfg3 36
  • 52.42 (n)
  • 42.08 (a)
zebrafish
(Danio rerio)
Actinopterygii ITFG3 37
  • 30 (a)
OneToMany
LOC796439 36
  • 46.56 (n)
  • 33.4 (a)
Species with no ortholog for ITFG3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ITFG3 Gene

ENSEMBL:
Gene Tree for ITFG3 (if available)
TreeFam:
Gene Tree for ITFG3 (if available)

Paralogs for ITFG3 Gene

Paralogs for ITFG3 Gene

genes like me logo Genes that share paralogs with ITFG3: view

Variants for ITFG3 Gene

Sequence variations from dbSNP and Humsavar for ITFG3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs8816 -- 265,840(+) GCTCT(A/G)TCCCT utr-variant-3-prime, intron-variant
rs13001 -- 266,054(-) TCCTT(A/G)GTGGG utr-variant-3-prime, intron-variant
rs739996 -- 266,447(-) CTACC(A/G)TCATC intron-variant, downstream-variant-500B
rs739997 -- 266,861(-) ACCCC(A/G)GTGAA intron-variant
rs739998 -- 266,891(-) CTCCC(A/G)TGCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ITFG3 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
nsv518291 CNV Loss 19592680
dgv2458n71 CNV Loss 21882294
nsv904652 CNV Loss 21882294
esv1473294 CNV Insertion 17803354
esv2660459 CNV Deletion 23128226
dgv32n68 CNV Loss 17160897
esv2667528 CNV Deletion 23128226
dgv2465n71 CNV Loss 21882294
dgv2466n71 CNV Loss 21882294
nsv904674 CNV Loss 21882294
nsv827477 CNV Gain 20364138
dgv2467n71 CNV Loss 21882294

Relevant External Links for ITFG3 Gene

HapMap Linkage Disequilibrium report
ITFG3

Disorders for ITFG3 Gene

Relevant External Links for ITFG3

Genetic Association Database (GAD)
ITFG3
Human Genome Epidemiology (HuGE) Navigator
ITFG3
genes like me logo Genes that share disorders with ITFG3: view

No data available for UniProtKB/Swiss-Prot for ITFG3 Gene

Publications for ITFG3 Gene

  1. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for ITFG3 Gene

Sources for ITFG3 Gene

Back to Top

Content