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ITFG1 Gene

protein-coding   GIFtS: 52
GCID: GC16M047188

Integrin Alpha FG-GAP Repeat Containing 1

  See ITFG1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Integrin Alpha FG-GAP Repeat Containing 11 2     2310047C21Rik2
TIP2 3 5     T-Cell Immunomodulatory Protein2
T Cell Immunomodulatory Protein1 2     Protein TIP3
Integrin-Alpha FG-GAP Repeat-Containing Protein 12 3     

External Ids:    HGNC: 306971   Entrez Gene: 815332   Ensembl: ENSG000001296367   OMIM: 6118035   UniProtKB: Q8TB963   

Export aliases for ITFG1 gene to outside databases

Previous GC identifers: GC16M045747 GC16M033078


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ITFG1 Gene:
ITFG1 (integrin alpha FG-GAP repeat containing 1) is a protein-coding gene. Diseases associated with ITFG1 include tethered spinal cord syndrome.

UniProtKB/Swiss-Prot: TIP_HUMAN, Q8TB96
Function: Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ITFG1 gene promoter:
         Sox5   AML1a   CUTL1   Gfi-1   GATA-1   CREB   NRF-2   deltaCREB   Zic1   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidITFG1 promoter sequence
   Search Chromatin IP Primers for ITFG1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ITFG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q12.1   Ensembl cytogenetic band:  16q12.1   HGNC cytogenetic band: 16q12.1

ITFG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ITFG1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M047188:  view genomic region     (about GC identifiers)

Start:
47,188,298 bp from pter      End:
47,498,060 bp from pter
Size:
309,763 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TIP_HUMAN, Q8TB96 (See protein sequence)
Recommended Name: T-cell immunomodulatory protein precursor  
Size: 612 amino acids; 68108 Da
Sequence caution: Sequence=AAG41782.1; Type=Frameshift; Positions=Several;
Secondary accessions: Q96SR4 Q9BRE2 Q9H2V9

Explore the universe of human proteins at neXtProt for ITFG1: NX_Q8TB96

Explore proteomics data for ITFG1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn36, Asn95, Asn139, Asn146, Asn151, Asn176, Asn188, Asn226, Asn243, Asn353,
                                 Asn371, Asn482
  • Modification sites at PhosphoSitePlus

  • See ITFG1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_110417.2  
    ENSEMBL proteins: 
     ENSP00000319918   ENSP00000441062   ENSP00000457665   ENSP00000459192   ENSP00000455630  

    ITFG1 Human Recombinant Protein Products:

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    Novus Biologicals ITFG1 Protein
    Novus Biologicals ITFG1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ITFG1

     
    Search eBioscience for Proteins for ITFG1 

     
    antibodies-online proteins for ITFG1 (3 products) 

     
    antibodies-online peptides for ITFG1

    ITFG1 Antibody Products:

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    Search for Antibodies for ITFG1 at Abcam
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    ThermoFisher Antibody for ITFG1
    antibodies-online antibodies for ITFG1 (19 products) 

    ITFG1 Assay Products:

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    Cloud-Clone Corp. ELISAs for ITFG1
    Cloud-Clone Corp. CLIAs for ITFG1
    Search eBioscience for ELISAs for ITFG1 
    antibodies-online kits for ITFG1 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR024881 Tip

    Graphical View of Domain Structure for InterPro Entry Q8TB96

    ProtoNet protein and cluster: Q8TB96

    UniProtKB/Swiss-Prot: TIP_HUMAN, Q8TB96
    Similarity: Belongs to the TIP family
    Similarity: Contains 1 FG-GAP repeat


    Find genes that share domains with ITFG1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TIP_HUMAN, Q8TB96
    Function: Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with ITFG1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ITFG1:
     Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ITFG1

    miRNA
    Products:
        
    miRTarBase miRNAs that target ITFG1:
    hsa-mir-23b-3p (MIRT046353), hsa-mir-26b-5p (MIRT028851)

    Block miRNA regulation of human, mouse, rat ITFG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ITFG1 (see all 24):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-300 hsa-miR-106a hsa-miR-302e hsa-miR-340 hsa-miR-520a-3p
    SwitchGear 3'UTR luciferase reporter plasmidITFG1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ITFG1
    Predesigned siRNA for gene silencing in human, mouse, rat ITFG1

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITFG1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITFG1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TIP_HUMAN, Q8TB96: Secreted (Potential). Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    plasma membrane3
    cytoskeleton1
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ITFG1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ITFG1
    Interactions:

        Search GeneGlobe Interaction Network for ITFG1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for ITFG1 (Q8TB962, 3 ENSP000003199184) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SERBP1Q8NC512, 3, ENSP000003600344MINT-8270209 I2D: score=2 STRING: ENSP00000360034
    CDC73Q6P1J92, 3MINT-8251131 I2D: score=2 
    FAM118BQ9BPY32, 3MINT-8255126 I2D: score=2 
    HMOX2P305192, 3MINT-8258321 I2D: score=2 
    MRPL44Q9H9J22, 3MINT-8263335 I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ITFG1 (TIP)

    2 Novoseek inferred chemical compound relationships for ITFG1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    4-hydroxyphenylpyruvate 73.5 1 7642122 (1)
    tyrosine 15.5 1 10490955 (1)



    Find genes that share compounds with ITFG1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ITFG1 gene: 
    NM_030790.3  

    Unigene Cluster for ITFG1:

    Integrin alpha FG-GAP repeat containing 1
    Hs.42217  [show with all ESTs]
    Unigene Representative Sequence: BC024162
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000568047 ENST00000320640(uc010vgg.2 uc002eet.3 uc010vgh.2)
    ENST00000537184 ENST00000542691 ENST00000567957 ENST00000544001 ENST00000565262
    ENST00000564825 ENST00000569551 ENST00000563350 ENST00000565940(uc010cbf.1)
    ENST00000563730
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ITFG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ITFG1 (see all 24):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-300 hsa-miR-106a hsa-miR-302e hsa-miR-340 hsa-miR-520a-3p
    SwitchGear 3'UTR luciferase reporter plasmidITFG1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ITFG1
    Predesigned siRNA for gene silencing in human, mouse, rat ITFG1
    Clone
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    OriGene clones in human, mouse for ITFG1 (see all 6)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ITFG1 (NM_030790)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ITFG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ITFG1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ITFG1
    OriGene qSTAR qPCR primer pairs in human, mouse for ITFG1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ITFG1
      QuantiTect SYBR Green Assays in human, mouse, rat ITFG1
      QuantiFast Probe-based Assays in human, mouse, rat ITFG1

    Additional mRNA sequence: 

    AF212247.1 AF503339.1 AK027596.1 AK094038.1 AK295228.1 AK299641.1 AK301908.1 AK309475.1 
    AL833705.1 BC006321.2 BC024162.1 

    18 DOTS entries:

    DT.317984  DT.317983  DT.208983  DT.95235144  DT.100031609  DT.100778013  DT.95235132  DT.100876702 
    DT.120729154  DT.120729265  DT.120729299  DT.95235131  DT.95235137  DT.95235140  DT.97772845  DT.40295534 
    DT.75107781  DT.91794433 

    Selected AceView cDNA sequences (see all 288):

    BM760222 NM_030790 AL517702 BM504892 CB132384 BQ718694 BC024162 BQ717110 
    CA418984 BM786665 BX509728 AW630557 BM976915 AA595681 BQ128306 AI659123 
    BX417587 Z44951 AA421149 AF503339 BQ286189 BF725919 AI335939 T06867 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ITFG1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                                            
    SP2:              -                                             
    SP3:                                                            


    ECgene alternative splicing isoforms for ITFG1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ITFG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGATGGAAA
    ITFG1 Expression
    About this image


    ITFG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 16) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    ITFG1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ITFG1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.42217

    UniProtKB/Swiss-Prot: TIP_HUMAN, Q8TB96
    Tissue specificity: Ubiquitously expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ITFG1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ITFG1 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Itfg11 , 5 integrin alpha FG-GAP repeat containing 11, 5 86.81(n)1
    89.66(a)1
      8 (41.61 cM)5
    719271  NM_028007.31  NP_082283.21 
     857175575 
    chicken
    (Gallus gallus)
    Aves ITFG11 integrin alpha FG-GAP repeat containing 1 76.49(n)
    80.24(a)
      415742  NM_001005840.1  NP_001005840.1 
    lizard
    (Anolis carolinensis)
    Reptilia ITFG16
    integrin alpha FG-GAP repeat containing 1
    74(a)
    1 ↔ 1
    LGc(3153509-3332800)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.328522 Xenopus laevis transcribed sequence with moderate similarity more 79.08(n)    CD326939.1 
    zebrafish
    (Danio rerio)
    Actinopterygii itfg11 integrin alpha FG-GAP repeat containing 1 62.99(n)
    68.79(a)
      100331534  XM_002662864.3  XP_002662910.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG77391 CG7739 49.08(n)
    41.14(a)
      39684  NM_140519.4  NP_648776.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2561 tag-256 46.86(n)
    32.26(a)
      176253  NM_066562.4  NP_498963.1 


    ENSEMBL Gene Tree for ITFG1 (if available)
    TreeFam Gene Tree for ITFG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ITFG1 (see all 4589)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1897765571,2
    --47188923(+) ACCACA/GTATTG 1 -- int10--------
    rs1150320491,2
    C,F--47189064(+) GCCAAG/CTTCAA 1 -- int11Minor allele frequency- C:0.07WA 118
    rs1823849131,2
    --47189071(+) TCAAAC/GAATGA 1 -- int10--------
    rs1863427641,2
    --47189241(+) AATTTC/GCATCA 1 -- int10--------
    rs1489180841,2
    --47189432(+) ACCCAA/GATTTT 1 -- ut310--------
    rs1910903571,2
    C--47189732(+) AAGATA/GTTATG 1 -- int10--------
    rs1140690581,2
    C--47189733(+) AGATGT/ATATGA 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1834964231,2
    --47189906(+) GAATAC/TTTAAG 1 -- int10--------
    rs1147086481,2
    C,F--47190017(+) GATTGC/TATTTT 1 -- int11Minor allele frequency- T:0.02WA 118
    rs120510571,2
    C,F--47190137(+) GAGGTG/AAGGAA 1 -- int17Minor allele frequency- A:0.43NA 132

    HapMap Linkage Disequilibrium report for ITFG1 (47188298 - 47438298 bp, first 250kb of ITFG1)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ITFG1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2671280CNV Deletion23128226
    nsv1796CNV Insertion18451855
    nsv906660CNV Loss21882294
    nsv510418CNV Loss20534489
    nsv528423CNV Loss19592680
    nsv520355CNV Gain19592680
    esv34317CNV Gain17911159
    nsv525170CNV Gain19592680
    nsv833217CNV Gain17160897
    dgv887e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ITFG1
    DNA2.0 Custom Variant and Variant Library Synthesis for ITFG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611803    OMIM disorders: --

    1 disease for ITFG1:    
    About MalaCards
    tethered spinal cord syndrome

    2 diseases from the University of Copenhagen DISEASES database for ITFG1:
    Tethered spinal cord syndrome     Spina bifida

    Find genes that share disorders with ITFG1           About GenesLikeMe

    1 Novoseek inferred disease relationship for ITFG1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia t-cell 53.6 1 16778109 (1)

    Genetic Association Database (GAD): ITFG1
    Human Genome Epidemiology (HuGE) Navigator: ITFG1 (1 document)

    Export disorders for ITFG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ITFG1 gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with ITFG1)
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    1. TIP, a T-cell factor identified using high-throughput screening increases survival in a graft-versus-host disease model. (PubMed id 12598909)1, 2, 3, 9 Fiscella M.... Migone T.-S. (Nat. Biotechnol. 2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (J. Proteome Res. 2012)
    6. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)
    10. Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway. (PubMed id 17384681)1 McConnell J.L.... Wadzinski B.E. (Oncogene 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81533 HGNC: 30697 AceView: CDA08 Ensembl:ENSG00000129636 euGenes: HUgn81533
    ECgene: ITFG1 H-InvDB: ITFG1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ITFG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ITFG1 gene:
    Search GeneIP for patents involving ITFG1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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