ISYNA1 Gene
protein-coding GIFtS: 57
GCID: GC19M018545
|
|
inositol-3-phosphate synthase 1
| |
Aliases
for ISYNA1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Inositol-3-Phosphate Synthase 11 2 | | MIP Synthase2 3 | | IPS1 2 5 | | EC 5.5.1.43 8 | | INOS1 2 | | Ino11 | | Myo-Inositol 1-Phosphate Synthase A12 3 | | IPS-12 | | INO12 3 | | HINO11 | | IPS 12 3 | | HIPS1 | | MI-1-P Synthase2 3 | | Myo-Inositol 1-Phosphate Synthase3 |
Export aliases for ISYNA1 gene to outside databasesPrevious GC identifers: GC19M019039 GC19M018937 GC19M018390 GC19M018406 GC19M018108 |
Summaries
for ISYNA1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ISYNA1:
This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in themyo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,and a pseudogene of this gene is located on the short arm of chromosome 4. (provided by RefSeq, Nov 2011)
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2Function: Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containingcompounds
|
Genomic Views
for ISYNA1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ISYNA1 gene promoter:
AP-2gamma FOXO1a AP-2beta c-Myb Zic3 NF-kappaB1 AP-2alpha FOXO1 AP-2alphaA Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for ISYNA1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISYNA1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.11 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.11ISYNA1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M018545: view genomic region
(about GC identifiers)
Start:
|
18,545,198 bp from pter |
End:
|
18,549,111 bp from pter |
Size:
|
3,914 bases |
Orientation:
|
minus strand |
|
Proteins
for ISYNA1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2 (See
protein sequence)Recommended Name: Inositol-3-phosphate synthase 1 Size: 558 amino acids; 61068 Da
Cofactor: NAD
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=AAP97151.1; Type=Frameshift; Positions=82, 85, 496;
Secondary accessions: B3KRT1 G5E9U0 Q6NXT5 Q7Z525 Q9BT65 Q9H2Y2 Q9NSU0 Q9NVW7Alternative splicing: 3 isoforms: Q9NPH2-1 Q9NPH2-2 Q9NPH2-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ISYNA1: NX_Q9NPH2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPH2
4/17 DME Specific Peptides for ISYNA1 (Q9NPH2) (see all 17)
ISYNA1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001164409.1 NP_001240318.1 NP_057452.1
ENSEMBL proteins: ENSP00000463628 ENSP00000337746 ENSP00000415458 ENSP00000464528 ENSP00000464209 ENSP00000463271 ENSP00000464438 ENSP00000461931 ENSP00000462001 ENSP00000463500 ENSP00000464430 ENSP00000315147 ENSP00000444679 Reactome Protein details: Q9NPH2
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
ISYNA1 for ontologies About GeneDecksing
ISYNA1 Antibody Products:
Assay Products for ISYNA1: |
Protein
Domains /
Families
for ISYNA1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ISYNA1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NPH2ProtoNet protein and cluster: Q9NPH2 1 Blocks protein family: IPB002587 Myo-inositol-1-phosphate synthase
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2Similarity: Belongs to the myo-inositol 1-phosphate synthase family |
Function
for ISYNA1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2Function: Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containingcompoundsCatalytic activity: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphateEnzyme regulation: Inhibited by mood-stabilizing drugs such as valproate (VPA) and lithiumBiophysicochemical properties: Kinetic parameters: KM=0.57 mM for 6-phosphate; KM=8 uM for NAD; pH dependence: OptimumpH is 8.0;Induction: By glucose and lovastain. Up-regulation is prevented by mevalonic acid, farnesol, and geranylgeraniol.Up-regulated by E2F1Enzyme Number (IUBMB): EC 5.5.1.41 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ISYNA1 (NM_016368) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISYNA1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISYNA1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISYNA1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0004512 | inositol-3-phosphate synthase activity |
IEA | -- |
ISYNA1 for ontologies About GeneDecksing
|
Pathways & Interactions
for ISYNA1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Inositol phosphate metabolism | | | 3 | Synthesis of IP3 and IP4 in the cytosol | | | 4 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for ISYNA1
2 
Kegg Pathways (Kegg details for ISYNA1):
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2Pathway: Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2
ISYNA1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ISYNA1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/71 Interacting proteins for ISYNA1 (Q9NPH22, 3 ENSP000003151474) via UniProtKB, MINT, STRING, and/or I2D (see all 71)
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006021 | inositol biosynthetic process |
IEA | -- | | GO:0008654 | phospholipid biosynthetic process |
IEA | -- |
ISYNA1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ISYNA1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ISYNA1
6 HMDB Compounds for ISYNA1 About this table
5 DrugBank Compounds for ISYNA1 About this table
Search CenterWatch for drugs/clinical trials and news about ISYNA1 / INO1
|
Transcripts
for ISYNA1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ISYNA1 gene (4 alternative transcripts): NM_001170938.1 NM_001253389.1 NM_016368.4 NM_001170939.1 Unigene Cluster for ISYNA1: Inositol-3-phosphate synthase 1 Hs.405873 [show with all ESTs]Unigene Representative Sequence: NM_01636818/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000582811 ENST00000338128(uc002njd.2 uc010xqh.2) ENST00000457269
ENST00000582287 ENST00000581672 ENST00000578963 ENST00000577916(uc002njb.2)
ENST00000582770 ENST00000577820 ENST00000585068 ENST00000583816 ENST00000583309
ENST00000582876 ENST00000579463 ENST00000580254 ENST00000578352 ENST00000580725
ENST00000581800
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ISYNA1 (NM_016368) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISYNA1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISYNA1 |
Additional cDNA sequence: AF086921.1 AF207640.1 AF220530.1 AK001325.1 AK021526.1 AK092179.1 AK093461.1 AK296022.1 AL137749.1 BC004320.1 BC018952.2 BC066902.1 NR_045573.1 NR_045574.1 24/25 DOTS entries (see all 25): DT.85104226 DT.95278735 DT.91962553 DT.100881957 DT.91758900 DT.95278499 DT.95143351 DT.100881953 DT.95278725 DT.100881959 DT.121437702 DT.100038846 DT.121437722 DT.95244852 DT.100753340 DT.121437670 DT.437496 DT.95229283 DT.97862521 DT.100881961 DT.121437675 DT.121437680 DT.121437698 DT.95294902 24/324 AceView cDNA sequences (see all 324): BF725260 AW299239 BP343122 CD243250 BU175947 BU844429 BU729143 BE645558 AI672316 BQ576061 BF116039 CD722506 BM797041 CD671206 AK021526 AI223232 BC018952 BQ002216 CK904441 AK092433 CD671205 AI814293 AI625790 BP343824
GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for ISYNA1 (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 11c | ^ | 12a | · | 12b | · | 12c |
|---|
|
| SP1: | - | | | | | | | | |
| SP2: | - | | | | | | | | |
| SP3: | - | | | | | | | | |
| SP4: | - | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for ISYNA1
|
Expression
for ISYNA1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ISYNA1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCCTGGAAC
About this image
See ISYNA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ISYNA1
SOURCE GeneReport for Unigene cluster: Hs.405873
UniProtKB/Swiss-Prot: INO1_HUMAN, Q9NPH2Tissue specificity: Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in bloodleukocyte, thymus, skeletal muscle and colon
SABiosciences Custom PCR Arrays for ISYNA1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISYNA1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ISYNA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISYNA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISYNA1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISYNA1 |
Orthologs
for ISYNA1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ISYNA1 gene from 7/30 species (see all 30) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Isyna11 , 5 |
myo-inositol 1-phosphate synthase A11, 5 |
82.37(n)1
88.67(a)1 |
|
8 (34.15 cM)5
717801 NM_023627.11 NP_076116.11
705944815 |
lizard
(Anolis carolinensis) |
Reptilia |
ISYNA16 |
-- |
76(a) |
1 ↔ 1 |
GL344399.1(21466-36495) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC526532 |
similar to myo-inositol 1-phosphate synthase A1 |
73.14(n) |
|
BC044073.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Inos1 , 3 |
inositol-3-phosphate synthase3
CG11143-PA1 |
61(a)3
66.73(n)1
63.04(a)1 |
|
43C43
356711 NM_058057.51 NP_477405.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
inos-11 |
Protein INOS-1 |
57.83(n)
54.42(a) |
|
174792 NM_064098.4 NP_496499.2 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
MIPS21 |
inositol-3-phosphate synthase isozyme 2 |
59.93(n)
61.2(a) |
|
816757 NM_127790.3 NP_179812.1 |
rice
(Oryza sativa) |
Liliopsida |
AK069323.12 |
-- |
74.77(n) |
|
AK069323.1 |
ENSEMBL Gene Tree for ISYNA1 (if available)
TreeFam Gene Tree for ISYNA1 (if available) |
Paralogs
for ISYNA1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ISYNA1 gene
ISYNA1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ISYNA1
PGOHUM00000245867
|
Genomic Variants
for ISYNA1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ISYNA1 (18545198 - 18549111 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ISYNA1: --
Human Gene Mutation Database (HGMD): ISYNA1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ISYNA1 |
|
Disorders
/ Diseases
for ISYNA1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ISYNA1 for disorders About GeneDecksing
OMIM gene information: 611670
OMIM disorders: --
13  diseases for ISYNA1: About MalaCardsradioulnar synostosis fungal meningitis synostosis whipple disease
cerebral palsy meningitis fainting osteonecrosis
bipolar disorder candidiasis cerebritis osteoarthritis
malaria
1 disease from the University of Copenhagen DISEASES database for ISYNA1:Fungal meningitis Export disorders for ISYNA1 gene to outside databases
|
Publications
for ISYNA1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ISYNA1 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with ISYNA1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast. (PubMed id 15024000)1, 2, 3 Ju S.... Greenberg M.L. (2004)
- cDNA cloning and gene expression analysis of human myo-inositol 1-phosphate synthase. (PubMed id 12941308)1, 2, 3 Guan G....Shechter I. (2003)
- E2F1 regulation of the human myo-inositol 1-phosphate synthase (ISYNA1) gene promoter. (PubMed id 15464731)1, 2 Seelan R.S.... Parthasarathy R.N. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- L-myo-inositol-1-phosphate synthase expressed in devel oping organ: isolation and characterisation of the enzyme from human fetal liver . (PubMed id 22707096)1 Chhetri D.R....Adhikari J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
|
External Searches for ISYNA1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ISYNA1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ISYNA1 gene
(According to HUGE)
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Specialized Databases showing ISYNA1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ISYNA1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for ISYNA1 gene:
Search GeneIP for patents involving ISYNA1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ISYNA1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ISYNA1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ISYNA1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISYNA1 | | | OriGene Protein Over-expression Lysate for ISYNA1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ISYNA1 | | OriGene 3'-UTR Clone for ISYNA1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISYNA1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ISYNA1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ISYNA1 | | OriGene Custom Protein Services for ISYNA1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ISYNA1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ISYNA1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISYNA1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISYNA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISYNA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISYNA1 |
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| | | | Search Tocris compounds for ISYNA1 |
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 | | | ISYNA1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISYNA1 |
|  |  |  | | | | Search ThermoFisher Antibodies for ISYNA1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISYNA1 |
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