IST1 Gene
protein-coding GIFtS: 49
GCID: GC16P071930
|
|
increased sodium tolerance 1 homolog (yeast)(Previous name: KIAA0174 ) (Previous symbol: KIAA0174)
| |
Aliases for IST1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Increased Sodium Tolerance 1 Homolog (Yeast)1 2 | | Overexpressed In Lung Cancer 12 | | KIAA01741 3 | | HIST11 | | Putative MAPK-Activating Protein PM282 3 | | CRS15 | | OLC12 | | SCS5 | | IST1 Homolog2 | | TWACS35 |
Export aliases for IST1 gene to outside databases |
Summaries for IST1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for IST1: This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexesrequired for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membraneabscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcriptvariants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Aug 2012) UniProtKB/Swiss-Prot: IST1_HUMAN, P53990Function: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscissionduring cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved inrecruiting VPS4A and/or VPS4B to the midbody of dividing cells Gene Wiki entry for IST1 (KIAA0174)
|
Genomic Views for IST1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for IST1 Other transcription factors
Search SABiosciences Chromatin IP Primers for IST1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IST1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.2 Ensembl cytogenetic band: 16q22.2 HGNC cytogenetic band: 16q22.2IST1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P071930: view genomic region
(about GC identifiers)
Start:
|
71,919,136 bp from pter |
End:
|
71,962,913 bp from pter |
Size:
|
43,778 bases |
Orientation:
|
plus strand |
|
Proteins for IST1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: IST1_HUMAN, P53990 (See
protein sequence)Recommended Name: IST1 homolog Size: 364 amino acids; 39751 Da
Subunit: Interacts with CHMP1A, CHMP1B, VPS4A and VTA1. Interacts with SPAST, STAMBP, USP8 and MITD1. May interact withVPS37B. May associate with the ESCRT-I complex
Subcellular location: Cytoplasmic vesicle. Note=Localizes to the midbody of dividing cells
Sequence caution: Sequence=BAA11491.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
2 PDB 3D structures from and Proteopedia for IST1:3FRR (3D)
  3FRS (3D)
 
Secondary accessions: Q3SYM4 Q9BQ81 Q9BWN2Alternative splicing: 4 isoforms: P53990-1 P53990-2 P53990-4 P53990-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IST1: NX_P53990
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P53990 IST1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001257904.1 NP_001257905.1 NP_001257906.1 NP_001257907.1 NP_001257908.1 NP_055576.2 ENSEMBL proteins: ENSP00000455409 ENSP00000457844 ENSP00000455860 ENSP00000455590 ENSP00000368076 ENSP00000457646 ENSP00000398505 ENSP00000330408 ENSP00000463711 ENSP00000455805 ENSP00000454541 ENSP00000368075 ENSP00000455757 ENSP00000410081 ENSP00000414942 ENSP00000463833 ENSP00000438399 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
IST1 for ontologies About GeneDecksing
IST1 Antibody Products: Assay Products for IST1: |
Protein
Domains / Families for IST1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IST1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P53990ProtoNet protein and cluster: P53990 1 Blocks protein family: IPB005061 Eukaryotic protein of unknown function DUF292
UniProtKB/Swiss-Prot: IST1_HUMAN, P53990Similarity: Belongs to the IST1 family |
Function for IST1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: IST1_HUMAN, P53990Function: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscissionduring cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved inrecruiting VPS4A and/or VPS4B to the midbody of dividing cells
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for IST1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IST1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IST1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IST1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
IST1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for IST1:
|
Pathways & Interactions for IST1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IST1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/33 Interacting proteins for IST1 (P539901, 2, 3 ENSP000003304084) via UniProtKB, MINT, STRING, and/or I2D (see all 33)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
IST1 for ontologies About GeneDecksing
|
Drugs & Compounds for IST1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for IST1 Search CenterWatch for drugs/clinical trials and news about IST1 
|
Transcripts for IST1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for IST1 gene (6 alternative transcripts): NM_001270975.1 NM_001270976.1 NM_001270977.1 NM_001270978.1 NM_001270979.1 NM_014761.3 Unigene Cluster for IST1: Increased sodium tolerance 1 homolog (yeast) Hs.232194 [show with all ESTs]Unigene Representative Sequence: NM_00127097618/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000540296 ENST00000544564 ENST00000541571 ENST00000538104 ENST00000378799(uc002fbj.1 uc010cgh.1 uc002fbm.1 uc002fbl.1) ENST00000537613 ENST00000424485 ENST00000566536 ENST00000538565(uc010vmk.1) ENST00000329908(uc002fbk.1) ENST00000538850 ENST00000541918 ENST00000534994 ENST00000378798(uc010vml.1) ENST00000539186 ENST00000439924 ENST00000545518 ENST00000456820
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for IST1 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IST1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IST1  |
Additional cDNA sequence: AB097052.1 AK057902.1 AK291388.1 AK293022.1 AK293040.1 AK295066.1 AK297088.1 AK297336.1 AK301918.1 AL355695.1 BC000116.1 BC000430.2 BC004359.1 BC038350.1 BC103745.1 D79996.1 24/55 DOTS entries (see all 55): DT.453442 DT.95271280 DT.100698519 DT.91846874 DT.100870610 DT.100758626 DT.100032330 DT.95271282 DT.121497621 DT.120688087 DT.95271275 DT.100870621 DT.120688096 DT.95294600 DT.120688206 DT.100870601 DT.100038885 DT.120688165 DT.91778252 DT.120688117 DT.120688212 DT.120688160 DT.100038887 DT.99997907 24/743 AceView cDNA sequences (see all 743): BM838889 AI754832 AI131322 BQ070997 BM918745 AL539540 BX333381 CK430481 CB989642 BI091271 AI079829 BU161700 BQ070938 AW173075 T36148 BM788524 BM834063 BG740294 BM848464 T33794 AI581173 BQ224170 BM827786 Z44478 GeneLoc Exon Structure
5/23 Alternative Splicing Database (ASD) splice patterns (SP) for IST1 (see all 23) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | |
| SP1: | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   |
| ExUns: | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | · | 17d | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for IST1
|
Expression for IST1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IST1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAGCTGTAGT
About this image See IST1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IST1
SOURCE GeneReport for Unigene cluster: Hs.232194 SABiosciences Custom PCR Arrays for IST1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IST1 Browse OriGene validated miRNA SYBR primer pairs
| |  | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat IST1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IST1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IST1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IST1 |
Orthologs for IST1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for IST1 gene from 9/25 species (see all 25) About this table
ENSEMBL Gene Tree for IST1 (if available) TreeFam Gene Tree for IST1 (if available)  |
Paralogs for IST1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for IST1 gene
- ENSG000002617502
IST1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for IST1 PGOHUM00000234683
|
Genomic Variants for IST1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for IST1 (71919136 - 71962913 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for IST1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IST1 |
|
Disorders
/ Diseases for IST1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IST1 for disorders About GeneDecksing
OMIM gene information: 601622 OMIM disorders: 101400 123100 7 diseases for IST1: About MalaCardssaethre-chotzen syndrome with eyelid anomalies saethre-chotzen syndrome lung cancer craniosynostosis conduct disorder adhd ataxia Export disorders for IST1 gene to outside databases
|
Publications for IST1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IST1 gene, integrated from 9 sources (see all 33): (articles sorted by number of sources associating them with IST1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Essential role of hIST1 in cytokinesis. (PubMed id 19129480)1, 2, 3 Agromayor M.... Martin-Serrano J. (2009)
- Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2, 3 Nagase T.... Nomura N. (1996)
- Biochemical analyses of human IST1 and its function in cytokinesis. (PubMed id 19129479)1, 2 Bajorek M....Sundquist W.I. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Differential requirements of mammalian ESCRTs in multi vesicular body formation, virus budding and cell division. (PubMed id 22340600)1 Morita E. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for IST1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing IST1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IST1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing IST1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for IST1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IST1 gene: Search GeneIP for patents involving IST1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for IST1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for IST1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IST1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IST1 | | OriGene Protein Over-expression Lysate for IST1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for IST1 | | OriGene 3'-UTR Clone for IST1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IST1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for IST1 | | OriGene Custom Protein Services for IST1 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IST1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IST1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IST1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IST1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IST1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IST1 |
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 |  |  |  | |
| | | Search Tocris compounds for IST1 |
| |  |  |  |  | | | | |
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 |
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 | | IST1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IST1 |
|  |  |  | | | ThermoFisher Antibody for IST1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IST1 |
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