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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IST1 Gene

protein-coding   GIFtS: 49
GCID: GC16P071930

increased sodium tolerance 1 homolog (yeast)

(Previous name: KIAA0174 )
(Previous symbol: KIAA0174)
 Explore 7 diseases affiliated with
IST1 via our new
 Human Malady Compendium 
Biological research products
for IST1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Increased Sodium Tolerance 1 Homolog (Yeast)1 2     Overexpressed In Lung Cancer 12
KIAA01741 3     HIST11
Putative MAPK-Activating Protein PM282 3     CRS15
OLC12     SCS5
IST1 Homolog2     TWACS35

External Ids:    HGNC: 289771   Entrez Gene: 97982   Ensembl: ENSG000001821497   OMIM: 6016225   UniProtKB: P539903   

Export aliases for IST1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IST1:
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes
required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane
abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript
variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: IST1_HUMAN, P53990
Function: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission
during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in
recruiting VPS4A and/or VPS4B to the midbody of dividing cells

Gene Wiki entry for IST1 (KIAA0174)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for IST1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIST1 promoter sequence
   Search SABiosciences Chromatin IP Primers for IST1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IST1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.2   Ensembl cytogenetic band:  16q22.2   HGNC cytogenetic band: 16q22.2

IST1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IST1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P071930:  view genomic region     (about GC identifiers)

Start:
71,919,136 bp from pter      End:
71,962,913 bp from pter
Size:
43,778 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IST1_HUMAN, P53990 (See protein sequence)
Recommended Name: IST1 homolog  
Size: 364 amino acids; 39751 Da
Subunit: Interacts with CHMP1A, CHMP1B, VPS4A and VTA1. Interacts with SPAST, STAMBP, USP8 and MITD1. May interact with
VPS37B. May associate with the ESCRT-I complex
Subcellular location: Cytoplasmic vesicle. Note=Localizes to the midbody of dividing cells
Sequence caution: Sequence=BAA11491.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
2 PDB 3D structures from and Proteopedia for IST1:
3FRR (3D)        3FRS (3D)    
Secondary accessions: Q3SYM4 Q9BQ81 Q9BWN2
Alternative splicing: 4 isoforms:  P53990-1   P53990-2   P53990-4   P53990-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IST1: NX_P53990

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P53990

  • IST1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (6 alternative transcripts): 
    NP_001257904.1  NP_001257905.1  NP_001257906.1  NP_001257907.1  NP_001257908.1  NP_055576.2  

    ENSEMBL proteins: 
     ENSP00000455409   ENSP00000457844   ENSP00000455860   ENSP00000455590   ENSP00000368076  
     ENSP00000457646   ENSP00000398505   ENSP00000330408   ENSP00000463711   ENSP00000455805  
     ENSP00000454541   ENSP00000368075   ENSP00000455757   ENSP00000410081   ENSP00000414942  
     ENSP00000463833   ENSP00000438399  

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    Uscn Proteins for IST1

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment IDA10942595
    GO:0005813centrosome IDA19129479
    GO:0005829cytosol IDA19129480
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--
    GO:0030496midbody IDA19129479


    IST1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IST1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR005061 DUF292_euk

    Graphical View of Domain Structure for InterPro Entry P53990

    ProtoNet protein and cluster: P53990

    1 Blocks protein family: IPB005061 Eukaryotic protein of unknown function DUF292

    UniProtKB/Swiss-Prot: IST1_HUMAN, P53990
    Similarity: Belongs to the IST1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: IST1_HUMAN, P53990
    Function: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission
    during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in
    recruiting VPS4A and/or VPS4B to the midbody of dividing cells

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidIST1 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
    GO:0019904protein domain specific binding IPI19129479
    GO:0032403protein complex binding IDA19129479


    IST1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for IST1:
     Wnt reporter downregulated 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IST1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/33 Interacting proteins for IST1 (P539901, 2, 3 ENSP000003304084) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542531, 2, 3, ENSP000002447694EBI-945994,EBI-930964 MINT-2867558 MINT-2855184 I2D: score=3 STRING: ENSP00000244769
    CAPN7Q9Y6W32, 3, ENSP000002536934MINT-7990176 MINT-7990213 MINT-7990252 MINT-7990193 MINT-7990233 I2D: score=1 STRING: ENSP00000253693
    CALM1P621583I2D: score=4 
    CALM2P621583I2D: score=4 
    CALM3P621583I2D: score=4 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle ----
    GO:0008104protein localization IMP--
    GO:0009838abscission IMP19525971
    GO:0019076viral release from host cell IDA19129479
    GO:0033205cell cycle cytokinesis IMP19129479


    IST1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IST1
    Search CenterWatch for drugs/clinical trials and news about IST1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IST1 gene (6 alternative transcripts): 
    NM_001270975.1  NM_001270976.1  NM_001270977.1  NM_001270978.1  NM_001270979.1  NM_014761.3  

    Unigene Cluster for IST1:

    Increased sodium tolerance 1 homolog (yeast)
    Hs.232194  [show with all ESTs]
    Unigene Representative Sequence: NM_001270976
    18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000540296 ENST00000544564 ENST00000541571 ENST00000538104 ENST00000378799(uc002fbj.1 uc010cgh.1 uc002fbm.1 uc002fbl.1)
    ENST00000537613 ENST00000424485 ENST00000566536 ENST00000538565(uc010vmk.1)
    ENST00000329908(uc002fbk.1) ENST00000538850 ENST00000541918 ENST00000534994
    ENST00000378798(uc010vml.1) ENST00000539186 ENST00000439924 ENST00000545518
    ENST00000456820

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    Inhib. RNA
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    Additional cDNA sequence: 

    AB097052.1 AK057902.1 AK291388.1 AK293022.1 AK293040.1 AK295066.1 AK297088.1 AK297336.1 
    AK301918.1 AL355695.1 BC000116.1 BC000430.2 BC004359.1 BC038350.1 BC103745.1 D79996.1 

    24/55 DOTS entries (see all 55):

    DT.453442  DT.95271280  DT.100698519  DT.91846874  DT.100870610  DT.100758626  DT.100032330  DT.95271282 
    DT.121497621  DT.120688087  DT.95271275  DT.100870621  DT.120688096  DT.95294600  DT.120688206  DT.100870601 
    DT.100038885  DT.120688165  DT.91778252  DT.120688117  DT.120688212  DT.120688160  DT.100038887  DT.99997907 

    24/743 AceView cDNA sequences (see all 743):

    BM838889 AI754832 AI131322 BQ070997 BM918745 AL539540 BX333381 CK430481 
    CB989642 BI091271 AI079829 BU161700 BQ070938 AW173075 T36148 BM788524 
    BM834063 BG740294 BM848464 T33794 AI581173 BQ224170 BM827786 Z44478 

    GeneLoc Exon Structure

    5/23 Alternative Splicing Database (ASD) splice patterns (SP) for IST1 (see all 23)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c · 10d ^ 11a · 11b · 11c · 11d ^ 12a ·
    SP1:              -     -     -     -     -     -                 -                             -     -                       -                                 
    SP2:                                      -     -                 -                             -     -                       -                                 
    SP3:                                      -     -                 -                             -     -                       -                                 
    SP4:                                      -     -                 -                             -     -                       -                                 
    SP5:                                      -     -                 -                             -     -                       -                                 

    ExUns: 12b ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c · 17d
    SP1:                                -     -                                 
    SP2:                                -     -                                 
    SP3:                                -     -                                 
    SP4:                    -     -     -     -                                 
    SP5:                                                                        


    ECgene alternative splicing isoforms for IST1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IST1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGCTGTAGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See IST1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IST1

    SOURCE GeneReport for Unigene cluster: Hs.232194
        SABiosciences Custom PCR Arrays for IST1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IST1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IST1 gene from 9/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ist11 , 5 RIKEN cDNA 2400003C14 gene5
    increased sodium tolerance 1 homolog (yeast)1
    89.63(n)1
    96.82(a)1
      8 (57.18 cM)5
    719551  NM_028018.21  NP_082294.11 
     1096713225 
    chicken
    (Gallus gallus)
    Aves KIAA01741 KIAA0174 81.52(n)
    91.58(a)
      415877  XM_414234.3  XP_414234.1 
    lizard
    (Anolis carolinensis)
    Reptilia IST16
    --
    69(a)
    1 → many
    GL343483.1(329183-335550)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.254312 Xenopus laevis transcribed sequence with strong similarity more 74.79(n)    48050902 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.11222 Danio rerio mRNA similar to KIAA0174 gene product (cDNA more 77.1(n)    BC045422.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG101031 CG10103 57.6(n)
    58.46(a)
      38750  NM_139801.2  NP_648058.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K10C8.31 Protein K10C8.3 57.95(n)
    55.96(a)
      179737  NM_073769.3  NP_506170.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G197106
    AT4G294406
    (see all 12)
    regulator of Vps4 activity protein
    (see all 12)
    8(a)
    7(a)
    (see all 12)
    many ↔ many
    many ↔ many
    (see all 12)
    2(8506130-8510081)
    4(14473757-14477935)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 10)
    DUF292 domain containing protein, expressed
    (see all 10)
    8(a)
    7(a)
    (see all 10)
    many ↔ many
    many ↔ many
    (see all 10)
    2(3212390-3216643)
    1(29305403-29311573)


    ENSEMBL Gene Tree for IST1 (if available)
    TreeFam Gene Tree for IST1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IST1 gene
    ENSG000002617502  

    IST1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for IST1
    PGOHUM00000234683


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/707 NCBI SNPs in IST1 are shown (see all 707    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1431024821,2
    --71926326(+) CACCAA/CGCCCG 1 -- us2k10--------
    rs1816425541,2
    --71926337(+) GCTAAA/TTTTTT 1 -- us2k10--------
    rs1871124321,2
    --71926422(+) CGCCTC/TGGCCT 1 -- us2k10--------
    rs1138896381,2
    C,--71926976(+) CACCCG/AGGCTG 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs118637711,2
    C,F,H,--71927008(+) gctcaC/Gtgcaa 1 -- us2k1 tfbs33Minor allele frequency- G:0.44NA WA CSA 9
    rs1163029571,2
    F,--71927021(+) TCTATC/GTCCTG 1 -- us2k11Minor allele frequency- G:0.07WA 118
    rs98069051,2
    C,H,--71927152(+) GTCTTG/CATCTC 1 -- us2k15Minor allele frequency- C:0.00NA CSA 11
    rs359891341,2
    C,F,--71927411(+) AGGCTG/AGAGTG 6 -- us2k12Minor allele frequency- A:0.50NA 4
    rs1895314911,2
    --71927448(+) ACCTCC/TGCCTC 6 -- us2k10--------
    rs1815939091,2
    --71927524(+) ACATCC/TGGCTA 6 -- us2k10--------

    HapMap Linkage Disequilibrium report for IST1 (71919136 - 71962913 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for IST1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IST1
    DNA2.0 Custom Variant and Variant Library Synthesis for IST1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IST1 for disorders           About GeneDecksing

    OMIM gene information: 601622   
    OMIM disorders: 101400  123100  
    7 diseases for IST1:    About MalaCards
    saethre-chotzen syndrome with eyelid anomalies    saethre-chotzen syndrome    lung cancer    craniosynostosis
    conduct disorder    adhd    ataxia


    Export disorders for IST1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IST1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with IST1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Essential role of hIST1 in cytokinesis. (PubMed id 19129480)1, 2, 3 Agromayor M.... Martin-Serrano J. (2009)
    2. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2, 3 Nagase T.... Nomura N. (1996)
    3. Biochemical analyses of human IST1 and its function in cytokinesis. (PubMed id 19129479)1, 2 Bajorek M....Sundquist W.I. (2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Differential requirements of mammalian ESCRTs in multi vesicular body formation, virus budding and cell division. (PubMed id 22340600)1 Morita E. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9798 HGNC: 28977 AceView: KIAA0174 Ensembl:ENSG00000182149 euGenes: HUgn9798
    ECgene: IST1 H-InvDB: IST1

    (According to HUGE)
    About This Section
    HUGE: KIAA0174

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IST1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IST1 gene:
    Search GeneIP for patents involving IST1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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