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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ISPD Gene

protein-coding   GIFtS: 41
GCID: GC07M016098

Isoprenoid Synthase Domain Containing

Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Isoprenoid Synthase Domain Containing1 2     MDDGA72
Notch1-Induced Protein1 2     Nip2
2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase-Like Protein2 3     Isoprenoid Synthase Domain-Containing Protein2
4-Diphosphocytidyl-2C-Methyl-D-Erythritol Synthase Homolog (Arabidopsis)1     EC 2.7.7.-3
4-Diphosphocytidyl-2C-Methyl-D-Erythritol Synthase Homolog2     

External Ids:    HGNC: 372761   Entrez Gene: 7299202   Ensembl: ENSG000002149607   OMIM: 6146315   UniProtKB: A4D1263   

Export aliases for ISPD gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ISPD Gene:
This gene encodes a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein. Mutations in this gene
are the cause of Walker-Warburg syndrome. Alternate splicing results in multiple transcript variants. (provided
by RefSeq, May 2012)

GeneCards Summary for ISPD Gene: 
ISPD (isoprenoid synthase domain containing) is a protein-coding gene. Diseases associated with ISPD include ispd-related muscle diseases, and walker-warburg syndrome. GO annotations related to this gene include nucleotidyltransferase activity.

UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126
Function: Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in
synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ISPD
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ISPD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISPD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.2   Ensembl cytogenetic band:  7p21.2   HGNC cytogenetic band: 7p21.2

ISPD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ISPD gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M016098:  view genomic region     (about GC identifiers)

Start:
16,127,152 bp from pter      End:
16,460,947 bp from pter
Size:
333,796 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 16,180,240-16,514,081     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126 (See protein sequence)
Recommended Name: Isoprenoid synthase domain-containing protein  
Size: 451 amino acids; 49873 Da
Sequence caution: Sequence=EAL24288.1; Type=Erroneous gene model prediction;
Secondary accessions: A8MU35 H9KVB2
Alternative splicing: 2 isoforms:  A4D126-1   A4D126-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ISPD: NX_A4D126

Explore proteomics data for ISPD at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A4D126

  • ISPD Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ISPD Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001094887.1  NP_001094896.1  

    ENSEMBL proteins: 
     ENSP00000385478   ENSP00000382249  

    Human Recombinant Protein Products for ISPD: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001228 ISPD_synthase
     IPR018294 ISPD_synthase_CS

    Graphical View of Domain Structure for InterPro Entry A4D126

    ProtoNet protein and cluster: A4D126

    UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126
    Similarity: Belongs to the IspD family


    ISPD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ISPD_HUMAN, A4D126
    Function: Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in
    synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation

         Enzyme Number (IUBMB): EC 2.7.7.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0016779nucleotidyltransferase activity IEA--
         
    ISPD for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ispd):
     cellular  mortality/aging  nervous system  other  respiratory system 

    ISPD for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ISPD 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ISPD

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ISPD 
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    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate ISPD (see all 13):
    hsa-miR-142-5p hsa-miR-548w hsa-miR-548j hsa-miR-607 hsa-miR-559 hsa-miR-3135 hsa-miR-548i hsa-miR-548h
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126
    Pathway: Protein modification; protein glycosylation

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ISPD

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008299isoprenoid biosynthetic process IEA--
    GO:0035269protein O-linked mannosylation IMP--

    ISPD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ISPD

    Search CenterWatch for drugs/clinical trials and news about ISPD

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ISPD gene (2 alternative transcripts): 
    NM_001101417.3  NM_001101426.3  

    Unigene Cluster for ISPD:

    Isoprenoid synthase domain containing
    Hs.636502  [show with all ESTs]
    Unigene Representative Sequence: NM_001101426
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000407010(uc010ktx.2) ENST00000399310(uc010kty.2) ENST00000479493

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate ISPD (see all 13):
    hsa-miR-142-5p hsa-miR-548w hsa-miR-548j hsa-miR-607 hsa-miR-559 hsa-miR-3135 hsa-miR-548i hsa-miR-548h
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Clone
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ISPD
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    Additional mRNA sequence: AK124805.1 

    5 DOTS entries:

    DT.100689799  DT.91690171  DT.100739914  DT.101955795  DT.86857343 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ISPD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAACACAA
    ISPD Expression
    About this image


    See ISPD Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.636502

    UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126
    Tissue specificity: Ubiquitously expressed, with high expression in brain

        SABiosciences Custom PCR Arrays for ISPD
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISPD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ISPD gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ispd1 , 5 isoprenoid synthase domain containing1, 5 78.45(n)1
    74.72(a)1
      12 (16.84 cM)5
    758471  NM_178629.51  NP_848744.21 
     363815195 
    chicken
    (Gallus gallus)
    Aves ISPD6
    isoprenoid synthase domain containing
    54(a)
    1 ↔ 1
    2(28433400-28521941)
    lizard
    (Anolis carolinensis)
    Reptilia ISPD6
    isoprenoid synthase domain containing
    50(a)
    1 ↔ 1
    6(27315576-27384275)
    zebrafish
    (Danio rerio)
    Actinopterygii ispd1 isoprenoid synthase domain containing 55.9(n)
    50(a)
      798716  NM_001077802.1  NP_001071270.1 


    ENSEMBL Gene Tree for ISPD (if available)
    TreeFam Gene Tree for ISPD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ISPD gene

    ISPD for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ISPD
    PGOHUM00000239597


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/7749 SNPs in ISPD are shown (see all 7749)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0681034
    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7)4--see VAR_0681032 A D mis40--------
    VAR_0681014
    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7)4--see VAR_0681012 A P mis40--------
    VAR_0681024
    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7)4--see VAR_0681022 R H mis40--------
    rs1387186021,2
    C--16014195(+) GCATG-/TACA  
            
    TACAT
    2 -- ut310--------
    rs355953881,2
    C--16048937(+) TTTCT-/T/TT  
            
    TTTTT
    2 -- int11NA 2
    rs16624911,2
    C--16088103(+) tccatC/Ttcttc 2 -- int11Minor allele frequency- T:0.50NA 2
    rs789884941,2
    C--16088924(-) TTGTCA/CACATT 2 -- int11Minor allele frequency- C:0.00NA 2
    rs132379991,2
    C,F,H--16100538(+) AGGCAA/TTGGGA 2 -- ds500121Minor allele frequency- N:0.00NS EA NA WA 2498
    rs171692591,2
    C,F--16100552(+) AAAGAT/CTATTT 2 -- ds50013Minor allele frequency- C:0.01NA 140
    rs1869483231,2
    --16100754(+) ATACAC/TGTAAT 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for ISPD (16127152 - 16377152 bp, first 250kb of ISPD)

    Structural Variations
         Database of Genomic Variants (DGV) 10/44 variations for ISPD (see all 44):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734055CNV Deletion23290073
    esv2734054CNV Deletion23290073
    esv5024CNV Deletion18987735
    nsv821416CNV Deletion20802225
    esv2658278CNV Deletion23128226
    esv2659119CNV Deletion23128226
    esv2734052CNV Deletion23290073
    esv2734053CNV Deletion23290073
    esv2661402CNV Deletion23128226
    dgv1185e199CNV Deletion23128226


    Human Gene Mutation Database (HGMD): ISPD

    Locus Specific Mutation Databases (LSDB): ISPD
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ISPD
    DNA2.0 Custom Variant and Variant Library Synthesis for ISPD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614631    OMIM disorders: --

    UniProtKB/Swiss-Prot: ISPD_HUMAN, A4D126
  • Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7) [MIM:614643]:
    An autosomal recessive disorder characterized by congenital muscular dystrophy associated with cobblestone
    lissencephaly and other brain anomalies, eye malformations, profound mental retardation, and death usually in the
    first years of life. Included diseases are the more severe Walker-Warburg syndrome and the slightly less severe
    muscle-eye-brain disease. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 12 diseases for ISPD:    About MalaCards
    ispd-related muscle diseases    walker-warburg syndrome    muscular dystrophy-dystroglycanopathy    muscle eye brain disease
    congenital muscular dystrophy    lissencephaly    brain disease    muscular dystrophy
    peritonitis    pneumonia    mental retardation    tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for ISPD:
    Peritonitis     Walker-Warburg syndrome

    ISPD for disorders           About GeneDecksing

    Genetic Association Database (GAD): ISPD
    Human Genome Epidemiology (HuGE) Navigator: ISPD (4 documents)

    Export disorders for ISPD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ISPD gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with ISPD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of alpha-dystroglycan. (PubMed id 22522421)1, 2 Roscioli T.... van Bokhoven H. (2012)
    2. ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome. (PubMed id 22522420)1, 2 Willer T.... Campbell K.P. (2012)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    5. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    6. The sequence of the human genome. (PubMed id 11181995)1, 3 Venter J.C.... Zhu X. (2001)
    7. Impact of four loci on serum tamsulosin hydrochloride concentration. (PubMed id 23151678)1 Takata R....Nakamura Y. (2013)
    8. ISPD gene mutations are a common cause of congenital a nd limb-girdle muscular dystrophies. (PubMed id 23288328)1 Cirak S....Muntoni F. (2013)
    9. Limb-girdle muscular dystrophy with a-dystroglycan def iciency and mutations in the ISPD gene. (PubMed id 23390185)1 Tasca G....Ricci E. (2013)
    10. Identification of mutations in TMEM5 and ISPD as a cau se of severe cobblestone lissencephaly. (PubMed id 23217329)1 Vuillaumier-Barrot S....Seta N. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 729920 HGNC: 37276 Ensembl:ENSG00000214960 euGenes: HUgn729920 ECgene: ISPD
    H-InvDB: ISPD

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ISPD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ISPD gene:
    Search GeneIP for patents involving ISPD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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     Proteins for ISPD
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     Search ThermoFisher Antibodies for ISPD
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ISPD
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ISPD
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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