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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ISOC2 Gene

protein-coding   GIFtS: 46
GCID: GC19M055964

Isochorismatase Domain Containing 2

  Search for ISOC2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Isochorismatase Domain Containing 21 2
Isochorismatase Domain-Containing Protein 2, Mitochondrial2

External Ids:    HGNC: 262781   Entrez Gene: 797632   Ensembl: ENSG000000632417   OMIM: 6129285   UniProtKB: Q96AB33   

Export aliases for ISOC2 gene to outside databases

Previous GC identifers: GC19M060657 GC19M052278


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ISOC2 Gene: 
ISOC2 (isochorismatase domain containing 2) is a protein-coding gene. GO annotations related to this gene include protein binding and catalytic activity. An important paralog of this gene is ISOC1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ISOC2 gene promoter:
         RFX1   NCX/Ncx   RREB-1   MyoD   GATA-1   CREB   deltaCREB   COMP1   FOXJ2   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidISOC2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ISOC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISOC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

ISOC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ISOC2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M055964:  view genomic region     (about GC identifiers)

Start:
55,964,345 bp from pter      End:
55,973,710 bp from pter
Size:
9,366 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ISOC2_HUMAN, Q96AB3 (See protein sequence)
Recommended Name: Isochorismatase domain-containing protein 2, mitochondrial precursor  
Size: 205 amino acids; 22337 Da
Subunit: Interacts with CDKN2A
Subcellular location: Mitochondrion (By similarity). Cytoplasm. Nucleus. Note=Localizes to the nucleus in the
presence of CDKN2A
Secondary accessions: Q6ZN91 Q9H5G0
Alternative splicing: 3 isoforms:  Q96AB3-1   Q96AB3-2   Q96AB3-3   

Explore the universe of human proteins at neXtProt for ISOC2: NX_Q96AB3

Explore proteomics data for ISOC2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96AB3

  • ISOC2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ISOC2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001129673.1  NP_001129674.1  NP_078986.1  

    ENSEMBL proteins: 
     ENSP00000406364   ENSP00000401726   ENSP00000085068   ENSP00000465814   ENSP00000467111  

    Human Recombinant Protein Products for ISOC2: 
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    Novus Biologicals ISOC2 Proteins
    Novus Biologicals ISOC2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ISOC2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA17658461
    GO:0005737cytoplasm IDA17658461
    GO:0005739mitochondrion IEA--

    ISOC2 for ontologies           About GeneDecksing



    ISOC2 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for ISOC2 
    Cloud-Clone Corp. CLIAs for ISOC2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000868 Isochorismatase-like

    Graphical View of Domain Structure for InterPro Entry Q96AB3

    ProtoNet protein and cluster: Q96AB3

    1 Blocks protein domain: IPB000868 Isochorismatase hydrolase family

    UniProtKB/Swiss-Prot: ISOC2_HUMAN, Q96AB3
    Similarity: Belongs to the isochorismatase family


    ISOC2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity IEA--
    GO:0005515protein binding IPI17658461
         
    ISOC2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ISOC2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ISOC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ISOC2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ISOC2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ISOC2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ISOC2:
    hsa-miR-579 hsa-miR-1538 hsa-miR-3180-3p hsa-miR-33b hsa-miR-450b-3p hsa-miR-33a hsa-miR-1180
    SwitchGear 3'UTR luciferase reporter plasmidISOC2 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Clone
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    OriGene clones in human, mouse for ISOC2 (see all 15)
    OriGene ORF clones in mouse, rat for ISOC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ISOC2 (NM_001136202)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ISOC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC2
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                         Customized lentivirus expression plasmids for stable overexpression of ISOC2 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ISOC2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/7 Interacting proteins for ISOC2 (Q96AB32, 3 ENSP000000850684) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDK2Q151192, 3, ENSP000000077084MINT-64225 I2D: score=4 STRING: ENSP00000007708
    NAA38O957773, ENSP000002492994I2D: score=4 STRING: ENSP00000249299
    LSM5Q9Y4Y93, ENSP000004107584I2D: score=1 STRING: ENSP00000410758
    FHP079543I2D: score=4 
    PSMA7O148183I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----
    GO:0031648protein destabilization IMP17658461

    ISOC2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ISOC2

    Search CenterWatch for drugs/clinical trials and news about ISOC2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ISOC2 gene (3 alternative transcripts): 
    NM_001136201.1  NM_001136202.1  NM_024710.2  

    Unigene Cluster for ISOC2:

    Isochorismatase domain containing 2
    Hs.467306  [show with all ESTs]
    Unigene Representative Sequence: AK097280
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000438389(uc002qlc.3) ENST00000590921 ENST00000425675(uc002qlb.3)
    ENST00000085068(uc002qla.3) ENST00000587226 ENST00000589080 ENST00000591718
    ENST00000589108
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ISOC2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ISOC2:
    hsa-miR-579 hsa-miR-1538 hsa-miR-3180-3p hsa-miR-33b hsa-miR-450b-3p hsa-miR-33a hsa-miR-1180
    SwitchGear 3'UTR luciferase reporter plasmidISOC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ISOC2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISOC2
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    OriGene clones in human, mouse for ISOC2 (see all 15)
    OriGene ORF clones in mouse, rat for ISOC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ISOC2 (NM_001136202)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ISOC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC2
    Sirion Biotech Customized lentivirus for stable overexpression of ISOC2 
                         Customized lentivirus expression plasmids for stable overexpression of ISOC2 
    Primer
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    OriGene qPCR primer pairs and template standards for ISOC2
    OriGene qSTAR qPCR primer pairs in human, mouse for ISOC2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISOC2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISOC2

    Additional mRNA sequence: 

    AK027122.1 AK097280.1 AK131324.1 BC017344.2 CR457377.1 

    10 DOTS entries:

    DT.213546  DT.97859036  DT.100792251  DT.121447478  DT.100792250  DT.92008197  DT.92430387  DT.100792253 
    DT.121447463  DT.121447471 

    24/194 AceView cDNA sequences (see all 194):

    BM675324 BU509142 NM_024710 BQ073810 CR597494 CB128629 AI638683 CB128098 
    CR608760 CB129680 AK027122 BQ636784 CB128076 CB113226 BF724485 BX395566 
    AI222424 CB120746 BF342058 BE795405 BF973364 AK131324 AW074293 BM458214 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ISOC2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c · 8d · 8e
    SP1:                    -                       -                                   -     -                           
    SP2:                    -                       -     -                             -     -                           
    SP3:                                            -     -                                                               
    SP4:                    -                       -     -                                                               
    SP5:                    -           -           -     -                             -     -                           


    ECgene alternative splicing isoforms for ISOC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ISOC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGACAGAGTG
    ISOC2 Expression
    About this image


    See ISOC2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ISOC2

    SOURCE GeneReport for Unigene cluster: Hs.467306
        SABiosciences Custom PCR Arrays for ISOC2
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ISOC2 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Isoc2a1 , 5 isochorismatase domain containing 2a1, 5 83.58(n)1
    84.24(a)1
      7 (2.82 cM)5
    6649941  NM_001101598.11  NP_001095068.11 
     48770535 
    lizard
    (Anolis carolinensis)
    Reptilia ISOC26
    Uncharacterized protein
    69(a)
    1 ↔ 1
    GL343279.1(868033-877989)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.189362 Transcribed sequence with weak similarity to protein more 76.63(n)    CK363062.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG36636
    CG113336
    --
    34(a)
    33(a)
    many ↔ many
    many ↔ many
    2R(20549047-20549940)
    3R(27289067-27289846)
    worm
    (Caenorhabditis elegans)
    Secernentea F35G2.21 Protein F35G2.2 53.86(n)
    55.26(a)
      178169  NM_069914.4  NP_502315.1 


    ENSEMBL Gene Tree for ISOC2 (if available)
    TreeFam Gene Tree for ISOC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ISOC2 gene
    ISOC12  
    1 SIMAP similar gene for ISOC2 using alignment to 3 protein entries:     ISOC2_HUMAN (see all proteins):
    ISOC1

    ISOC2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/303 SNPs in ISOC2 are shown (see all 303)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs342161961,2
    C--52278005(+) GCAGAG/-TTCCA 3 -- ds50011Minor allele frequency- -:0.00CSA 2
    rs784606961,2
    C--55963897(+) TACAAT/GGCTTT 3 -- ds50014Minor allele frequency- G:0.09CSA WA NA EA 359
    rs1469118901,2
    --55964091(+) GGGGGG/TCGGCC 3 -- ds50010--------
    rs1513251821,2
    C--55964150(+) GCGCGA/CCGGCT 3 -- ds50010--------
    rs1411019651,2
    C--55964261(+) CACCT-/CCCCCC 3 -- ds50010--------
    rs3740378031,2
    C--55964261(+) GCACC-/CCCCCCC 3 -- ds50010--------
    rs579968881,2
    C,F--55964325(+) GGGATC/TCCCCC 3 -- ds50013Minor allele frequency- T:0.15WA NA EA 358
    rs31702641,2
    C--55964464(-) GAGCCA/G/TAGATG 6 -- ut315CSA WA NA EA 360
    rs1142270241,2
    C,F--55964554(+) CCCCCC/AACAAG 3 -- ut313Minor allele frequency- A:0.03WA NA EA 358
    rs23030891,2
    C,F,H--55964720(-) GACAGC/TGGACT 6 S syn1 ese322Minor allele frequency- T:0.08EA NS NA CSA WA EU 8858

    HapMap Linkage Disequilibrium report for ISOC2 (55964345 - 55973710 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for ISOC2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2718968CNV Deletion23290073
    esv2718969CNV Deletion23290073
    nsv912478CNV Loss21882294
    nsv912473CNV Loss21882294
    nsv912457CNV Loss21882294
    dgv4023n71CNV Loss21882294
    nsv912463CNV Loss21882294
    dgv4022n71CNV Loss21882294
    dgv4021n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ISOC2
    DNA2.0 Custom Variant and Variant Library Synthesis for ISOC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ISOC2 for disorders           About MalaCards
    OMIM gene information: 612928    OMIM disorders: --


    ISOC2 for disorders           About GeneDecksing


    Export disorders for ISOC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ISOC2 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with ISOC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a. (PubMed id 17658461)1, 2, 3 Huang X....Fu S. (2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    9. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79763 HGNC: 26278 AceView: FLJ23469 Ensembl:ENSG00000063241 euGenes: HUgn79763
    ECgene: ISOC2 H-InvDB: ISOC2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ISOC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ISOC2 gene:
    Search GeneIP for patents involving ISOC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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