ISOC2 Gene
protein-coding GIFtS: 45
GCID: GC19M055964
|
|
isochorismatase domain containing 2
| |
Aliases
for ISOC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Isochorismatase Domain Containing 21 2 | | FLJ234691 | | Isochorismatase Domain-Containing Protein 2, Mitochondrial2 |
Export aliases for ISOC2 gene to outside databasesPrevious GC identifers: GC19M060657 GC19M052278 |
Summaries
for ISOC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ISOC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ISOC2 gene promoter:
RFX1 NCX/Ncx RREB-1 MyoD GATA-1 CREB deltaCREB COMP1 FOXJ2 Msx-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ISOC2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISOC2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.42ISOC2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M055964: view genomic region
(about GC identifiers)
Start:
|
55,964,345 bp from pter |
End:
|
55,973,710 bp from pter |
Size:
|
9,366 bases |
Orientation:
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minus strand |
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Proteins
for ISOC2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ISOC2_HUMAN, Q96AB3 (See
protein sequence)Recommended Name: Isochorismatase domain-containing protein 2, mitochondrial precursor Size: 205 amino acids; 22337 Da
Subunit: Interacts with CDKN2A
Subcellular location: Mitochondrion (By similarity). Cytoplasm. Nucleus. Note=Localizes to the nucleus in the presenceof CDKN2A
Secondary accessions: Q6ZN91 Q9H5G0Alternative splicing: 3 isoforms: Q96AB3-1 Q96AB3-2 Q96AB3-3 Explore the universe of human proteins at neXtProt for ISOC2: NX_Q96AB3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96AB3
ISOC2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001129673.1 NP_001129674.1 NP_078986.1
ENSEMBL proteins: ENSP00000406364 ENSP00000401726 ENSP00000085068 ENSP00000465814 ENSP00000467111
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ISOC2 for ontologies About GeneDecksing
ISOC2 Antibody Products:
Assay Products for ISOC2: |
Protein
Domains /
Families
for ISOC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ISOC2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96AB3ProtoNet protein and cluster: Q96AB3 1 Blocks protein family: IPB000868 Isochorismatase hydrolase family
UniProtKB/Swiss-Prot: ISOC2_HUMAN, Q96AB3Similarity: Belongs to the isochorismatase family |
Function
for ISOC2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ISOC2 (NM_001136202) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISOC2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ISOC2 for ontologies About GeneDecksing
|
Pathways & Interactions
for ISOC2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ISOC2
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/7 Interacting proteins for ISOC2 (Q96AB32, 3 ENSP000000850684) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
ISOC2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ISOC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ISOC2
Search CenterWatch for drugs/clinical trials and news about ISOC2
|
Transcripts
for ISOC2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ISOC2 gene (3 alternative transcripts): NM_001136201.1 NM_001136202.1 NM_024710.2 Unigene Cluster for ISOC2: Isochorismatase domain containing 2 Hs.467306 [show with all ESTs]Unigene Representative Sequence: AK0972808 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000438389(uc002qlc.3) ENST00000590921 ENST00000425675(uc002qlb.3)
ENST00000085068(uc002qla.3) ENST00000587226 ENST00000589080 ENST00000591718
ENST00000589108
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ISOC2 (NM_001136202) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISOC2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC2 |
Additional cDNA sequence: AK027122.1 AK097280.1 AK131324.1 BC017344.2 CR457377.1 10 DOTS entries: DT.213546 DT.97859036 DT.100792251 DT.121447478 DT.100792250 DT.92008197 DT.92430387 DT.100792253 DT.121447463 DT.121447471 24/194 AceView cDNA sequences (see all 194): CB128098 CB128629 NM_024710 BQ073810 AW074293 AK027122 BQ636784 BF342058 CB128076 AI638683 AI222424 BX395566 BU509142 CR597494 BE795405 BF973364 CB129680 BM675324 CB113226 BM458214 CR609552 BF724485 AK131324 CR608760
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ISOC2 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e |
|---|
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| SP1: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | - | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ISOC2
|
Expression
for ISOC2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ISOC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGACAGAGTG
About this image
See ISOC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ISOC2
SOURCE GeneReport for Unigene cluster: Hs.467306
SABiosciences Custom PCR Arrays for ISOC2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISOC2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ISOC2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISOC2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISOC2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC2 |
Orthologs
for ISOC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ISOC2 gene from 4/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
ISOC26 |
-- |
69(a) |
1 ↔ 1 |
GL343279.1(872608-877188) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.189362 |
Transcribed sequence with weak similarity to protein more |
76.63(n) |
|
CK363062.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG36636CG113336 |
-- |
34(a)33(a) |
possible orthologpossible ortholog |
2R(20549047-20549940) 3R(27289067-27289846) |
worm
(Caenorhabditis elegans) |
Secernentea |
F35G2.21 |
Protein F35G2.2 |
53.86(n)
55.26(a) |
|
178169 NM_069914.4 NP_502315.1 |
ENSEMBL Gene Tree for ISOC2 (if available)
TreeFam Gene Tree for ISOC2 (if available) |
Paralogs
for ISOC2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ISOC2 gene
- ISOC12
1 SIMAP similar gene for ISOC2 using alignment to 3 protein entries: ISOC2_HUMAN (see all proteins):ISOC1
ISOC2 for paralogs About GeneDecksing
|
Genomic Variants
for ISOC2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ISOC2 (55964345 - 55973710 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ISOC2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ISOC2 |
|
Disorders
/ Diseases
for ISOC2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ISOC2 for disorders About MalaCards
ISOC2 for disorders About GeneDecksing
OMIM gene information: 612928
OMIM disorders: --
Export disorders for ISOC2 gene to outside databases
|
Publications
for ISOC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ISOC2 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with ISOC2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a. (PubMed id 17658461)1, 2, 3 Huang X....Fu S. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
|
External Searches for ISOC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ISOC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ISOC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ISOC2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ISOC2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ISOC2 gene:
Search GeneIP for patents involving ISOC2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ISOC2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ISOC2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ISOC2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISOC2 | | | OriGene Protein Over-expression Lysate for ISOC2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ISOC2 | | OriGene 3'-UTR Clone for ISOC2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISOC2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ISOC2 | | OriGene Custom Protein Services for ISOC2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ISOC2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ISOC2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISOC2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISOC2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISOC2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISOC2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ISOC2 |
| |  |  |  |  | | | | |
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 |
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 | | | ISOC2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC2 |
|  |  |  | | | | Search ThermoFisher Antibodies for ISOC2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC2 |
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