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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ISOC1 Gene

protein-coding   GIFtS: 47
GCID: GC05P128430

Isochorismatase Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Isochorismatase Domain Containing 11 2
Isochorismatase Domain-Containing Protein 12

External Ids:    HGNC: 242541   Entrez Gene: 510152   Ensembl: ENSG000000665837   UniProtKB: Q96CN73   

Export aliases for ISOC1 gene to outside databases

Previous GC identifers: GC05P128459 GC05P123621


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ISOC1 Gene: 
ISOC1 (isochorismatase domain containing 1) is a protein-coding gene. Diseases associated with ISOC1 include uterine fibroid, and leiomyoma. GO annotations related to this gene include molecular_function and catalytic activity. An important paralog of this gene is ISOC2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ISOC1 gene promoter:
         Tal-1   AML1a   Brachyury   POU3F2   FOXL1   E47   PPAR-gamma1   POU2F1   Chx10   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidISOC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ISOC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISOC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q22.1-q33.3   Ensembl cytogenetic band:  5q23.3   HGNC cytogenetic band: 5q22.1-q33.3

ISOC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ISOC1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P128430:  view genomic region     (about GC identifiers)

Start:
128,430,442 bp from pter      End:
128,449,721 bp from pter
Size:
19,280 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ISOC1_HUMAN, Q96CN7 (See protein sequence)
Recommended Name: Isochorismatase domain-containing protein 1  
Size: 298 amino acids; 32237 Da
Sequence caution: Sequence=AAH08367.1; Type=Erroneous initiation; Sequence=AAH14105.2; Type=Erroneous initiation;
Secondary accessions: Q7Z770

Explore the universe of human proteins at neXtProt for ISOC1: NX_Q96CN7

Explore proteomics data for ISOC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96CN7

  • ISOC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ISOC1 Protein Expression
    REFSEQ proteins: NP_057132.2  
    ENSEMBL proteins: 
     ENSP00000421273   ENSP00000173527  

    Human Recombinant Protein Products for ISOC1: 
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    OriGene Protein Over-expression Lysate for ISOC1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ISOC1
    GenScript Custom Purified and Recombinant Proteins Services for ISOC1
    Novus Biologicals ISOC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ISOC1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome ISS14561759

    ISOC1 for ontologies           About GeneDecksing



    ISOC1 Antibody Products: 
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    Search ThermoFisher Antibodies for ISOC1
    LSBio Antibodies in human, mouse, rat for ISOC1 

    Assay Products for ISOC1: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for ISOC1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ISOC1 
    Cloud-Clone Corp. CLIAs for ISOC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000868 Isochorismatase-like

    Graphical View of Domain Structure for InterPro Entry Q96CN7

    ProtoNet protein and cluster: Q96CN7

    1 Blocks protein domain: IPB000868 Isochorismatase hydrolase family

    UniProtKB/Swiss-Prot: ISOC1_HUMAN, Q96CN7
    Similarity: Belongs to the isochorismatase family


    ISOC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003824catalytic activity IEA--
         
    ISOC1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ISOC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ISOC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ISOC1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ISOC1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ISOC1
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate ISOC1 (see all 12):
    hsa-miR-601 hsa-miR-15a hsa-miR-3065-3p hsa-miR-497 hsa-miR-513b hsa-miR-424 hsa-miR-3658 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidISOC1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ISOC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISOC1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ISOC1
    Sirion Biotech Customized adenovirus for overexpression of ISOC1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ISOC1 (see all 8)
    OriGene ORF clones in mouse, rat for ISOC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ISOC1 (NM_016048)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ISOC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC1
    Sirion Biotech Customized lentivirus for stable overexpression of ISOC1 
                         Customized lentivirus expression plasmids for stable overexpression of ISOC1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ISOC1
    Search LifeMap BioReagents cell lines for ISOC1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ISOC1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ISOC1 (Q96CN73 ENSP000001735274) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP1LC3CQ9BXW43I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    LSM5ENSP000004107584STRING: ENSP00000410758
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0008152metabolic process ----

    ISOC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ISOC1

    Search CenterWatch for drugs/clinical trials and news about ISOC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ISOC1 gene: 
    NM_016048.2  

    Unigene Cluster for ISOC1:

    Isochorismatase domain containing 1
    Hs.483296  [show with all ESTs]
    Unigene Representative Sequence: BC008367
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514194 ENST00000173527(uc003kva.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ISOC1
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate ISOC1 (see all 12):
    hsa-miR-601 hsa-miR-15a hsa-miR-3065-3p hsa-miR-497 hsa-miR-513b hsa-miR-424 hsa-miR-3658 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidISOC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ISOC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISOC1
    Clone
    Products:
         
    OriGene clones in human, mouse for ISOC1 (see all 8)
    OriGene ORF clones in mouse, rat for ISOC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ISOC1 (NM_016048)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ISOC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISOC1
    Sirion Biotech Customized lentivirus for stable overexpression of ISOC1 
                         Customized lentivirus expression plasmids for stable overexpression of ISOC1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ISOC1
    OriGene qSTAR qPCR primer pairs in human, mouse for ISOC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ISOC1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISOC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISOC1

    Additional mRNA sequence: 

    AK025787.1 BC008367.1 BC014105.2 

    7 DOTS entries:

    DT.216113  DT.120835017  DT.120835027  DT.91753017  DT.95103648  DT.100696922  DT.100781396 

    24/199 AceView cDNA sequences (see all 199):

    AI290685 AI261948 BC014105 AI279090 BP371761 BQ638646 CR623281 BF590261 
    BG613927 CB119742 AI571478 AA370947 AA953701 AA206816 AW965086 AI274397 
    AI433290 BF313710 AA918859 BX115260 AI346747 AI023604 BG493211 AI433828 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ISOC1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:                                          
    SP2:        -                                 


    ECgene alternative splicing isoforms for ISOC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ISOC1 expression in normal human tissues (normalized intensities)      ISOC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTGTTCTA
    ISOC1 Expression
    About this image


    ISOC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)
             Umbilical cord blood-derived hematopoietic stem cells
     
     Blood (Hematopoietic System)
             Umbilical cord blood-derived hematopoietic stem cells
     
     Limb (Muscoskeletal System)

    See ISOC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ISOC1

    SOURCE GeneReport for Unigene cluster: Hs.483296
        SABiosciences Custom PCR Arrays for ISOC1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ISOC1
    OriGene qSTAR qPCR primer pairs in human, mouse for ISOC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ISOC1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISOC1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISOC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISOC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ISOC1 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Isoc11 , 5 isochorismatase domain containing 11, 5 86.76(n)1
    94.95(a)1
      18 (33.71 cM)5
    663071  NM_025478.31  NP_079754.21 
     586594825 
    chicken
    (Gallus gallus)
    Aves ISOC11 isochorismatase domain containing 1 82.28(n)
    93.31(a)
      415601  XM_413969.3  XP_413969.2 
    lizard
    (Anolis carolinensis)
    Reptilia ISOC16
    Uncharacterized protein
    81(a)
    1 ↔ 1
    2(30450647-30463770)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.299622 Xenopus laevis transcribed sequence with weak similarity more 78.52(n)    BJ623511.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BQ074365.12   -- 79.19(n)    BQ074365.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG36631 CG3663 52.92(n)
    45.2(a)
      37944  NM_138108.2  NP_611952.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F35G2.26
    Protein F35G2.2
    46(a)
    1 → many
    IV(12208188-12209049)


    ENSEMBL Gene Tree for ISOC1 (if available)
    TreeFam Gene Tree for ISOC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ISOC1 gene
    ISOC22  
    1 SIMAP similar gene for ISOC1 using alignment to 2 protein entries:     ISOC1_HUMAN (see all proteins):
    ISOC2

    ISOC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/392 SNPs in ISOC1 are shown (see all 392)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs584988611,2
    C,F--128428481(+) TTTCTA/GGTAAC 1 -- us2k19Minor allele frequency- G:0.19WA NA CSA EA 368
    rs1832447431,2
    --128428550(+) GTGCAG/TTCACC 1 -- us2k10--------
    rs732324891,2
    C,F--128428555(+) TTCACG/CTCCCT 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs37567431,2
    C,H--128428689(+) AAACTA/GGGTTG 1 -- us2k15Minor allele frequency- G:0.01EA NS 1540
    rs2007459101,2
    --128428721(+) ACAAT-/GGATATA 1 -- us2k10--------
    rs37567441,2
    C,F--128428722(+) ACAATA/GTATAT 1 -- us2k13Minor allele frequency- G:0.18WA NA EA 358
    rs37567451,2
    C,F--128428723(+) CAATAT/GATATG 1 -- us2k13Minor allele frequency- G:0.18WA NA EA 358
    rs1918414841,2
    --128428818(+) GGCCAC/TGGCAG 1 -- us2k10--------
    rs37567461,2
    C,F,A,H--128428851(+) CCTCGC/TTGAGG 1 -- us2k117Minor allele frequency- T:0.18NS EA NA WA 2340
    rs1839737871,2
    --128428891(+) TCCAAC/TCTACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ISOC1 (128430442 - 128449721 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ISOC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv882847CNV Loss21882294
    nsv882849CNV Loss21882294
    nsv882848CNV Loss21882294
    nsv882842CNV Loss21882294
    nsv830485CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ISOC1
    DNA2.0 Custom Variant and Variant Library Synthesis for ISOC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ISOC1:    About MalaCards
    uterine fibroid    leiomyoma

    1 disease from the University of Copenhagen DISEASES database for ISOC1:
    Uterine fibroid

    ISOC1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ISOC1

    Export disorders for ISOC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ISOC1 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with ISOC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Microarray study of gene expression in uterine leiomyoma. (PubMed id 18566572)1, 3 Litovkin K.V....Zaporozhan V.N. (2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 3 Lai C.H....Lin W. (2000)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    8. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    9. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (2007)
    10. Proteomic analysis of rat liver peroxisome: presence of peroxisome- specific isozyme of Lon protease. (PubMed id 14561759)1 Kikuchi M....Taniguchi H. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51015 HGNC: 24254 AceView: CGI-111 Ensembl:ENSG00000066583 euGenes: HUgn51015
    ECgene: ISOC1 H-InvDB: ISOC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ISOC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ISOC1 gene:
    Search GeneIP for patents involving ISOC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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