Aliases for ISG20 Gene
External Ids for ISG20 Gene
GeneCards Summary for ISG20 Gene
ISG20 (Interferon Stimulated Exonuclease Gene 20kDa) is a Protein Coding gene. Diseases associated with ISG20 include mast cell disease and malignant glioma. Among its related pathways are Interferon Signaling and Interferon Signaling. GO annotations related to this gene include exonuclease activity and single-stranded DNA 3-5 exodeoxyribonuclease activity. An important paralog of this gene is ISG20L2.
UniProtKB/Swiss-Prot for ISG20 Gene
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.