ISCU Gene
protein-coding GIFtS: 61
GCID: GC12P108956
|
|
iron-sulfur cluster scaffold homolog (E. coli)(Previous names: NifU-like N-terminal domain containing, IscU iron-sulfur...)
(Previous symbol: NIFUN)
| |
Aliases
for ISCU gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Iron-Sulfur Cluster Scaffold Homolog (E. Coli)1 2 | | HML2 5 | | NIFUN1 2 3 | | IscU1 | | ISU21 2 | | IscU Iron-Sulfur Cluster Scaffold Homolog (E. Coli)1 | | HnifU1 | | 2310020H20Rik2 | | NifU-Like N-Terminal Domain Containing1 2 | | NIFU2 | | NifU-Like N-Terminal Domain-Containing Protein2 3 | | Iron-Sulfur Cluster Assembly Enzyme ISCU, Mitochondrial2 | | NifU-Like Protein2 3 | | IscU Iron-Sulfur Cluster Scaffold Homolog2 |
Export aliases for ISCU gene to outside databasesPrevious GC identifers: GC12P107458 GC12P107459 GC12P106020 |
Summaries
for ISCU gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ISCU:
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins.They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors,chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S clusterscaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intoleranceand myoglobinuria. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1Function: Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron
Gene Wiki entry for ISCU
|
Genomic Views
for ISCU gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ISCU gene promoter:
Pax-5 AML1a NCX/Ncx XBP-1 CUTL1 E4BP4 Evi-1 C/EBPalpha FOXO4
Other transcription factors
Search SABiosciences Chromatin IP Primers for ISCU
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISCU |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.1 Ensembl cytogenetic band: 12q23.3 HGNC cytogenetic band: 12q24.1ISCU Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P108956: view genomic region
(about GC identifiers)
Start:
|
108,956,294 bp from pter |
End:
|
108,963,160 bp from pter |
Size:
|
6,867 bases |
Orientation:
|
plus strand |
|
Proteins
for ISCU gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1 (See
protein sequence)Recommended Name: Iron-sulfur cluster assembly enzyme ISCU, mitochondrial precursor Size: 167 amino acids; 17999 Da
Subunit: Binds NFS1. Interacts with HSCB
Subcellular location: Isoform 1: Mitochondrion
Subcellular location: Isoform 2: Cytoplasm. Nucleus
Secondary accessions: Q6P713 Q99617 Q9H1K2Alternative splicing: 2 isoforms: Q9H1K1-1 Q9H1K1-2 Explore the universe of human proteins at neXtProt for ISCU: NX_Q9H1K1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H1K1
ISCU Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_055116.1 NP_998760.1
ENSEMBL proteins: ENSP00000445598 ENSP00000411108 ENSP00000446606 ENSP00000310623 ENSP00000437854 ENSP00000376554 ENSP00000443272 ENSP00000344584 Reactome Protein details: Q9H1K1
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ISCU for ontologies About GeneDecksing
ISCU Antibody Products:
Assay Products for ISCU: |
Protein
Domains /
Families
for ISCU gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ISCU for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H1K1ProtoNet protein and cluster: Q9H1K1 2 Blocks protein families: IPB002871 Nitrogen-fixing NifU-like IPB011339 FeS cluster assembly scaffold IscU
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1Similarity: Belongs to the NifU family |
Function
for ISCU gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1Function: Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ISCU (NM_213595) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISCU | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISCU |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISCU |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ISCU for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ISCU:
|
Pathways & Interactions
for ISCU gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Mitochondrial Iron-Sulfur Cluster Biogenesis | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for ISCU
ISCU for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ISCU
STRING Interaction
Network Preview (showing 5 interactants - click image to see 21)
5/33 Interacting proteins for ISCU (Q9H1K12, 3 ENSP000003106234) via UniProtKB, MINT, STRING, and/or I2D (see all 33)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
ISCU for ontologies About GeneDecksing
|
Drugs & Compounds
for ISCU gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ISCU for compounds About GeneDecksing
 Browse Tocris compounds for ISCU
1 HMDB Compound for ISCU About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Iron | Armco iron (see all 19) | 7439-89-6 | -- |
4 Novoseek chemical compound relationships for ISCU gene About this table
Search CenterWatch for drugs/clinical trials and news about ISCU
|
Transcripts
for ISCU gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ISCU gene (2 alternative transcripts): NM_014301.3 NM_213595.2 Unigene Cluster for ISCU: Iron-sulfur cluster scaffold homolog (E. coli) Hs.615131 [show with all ESTs]Unigene Representative Sequence: AK05725114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000545932(uc010sxb.1 uc010sxd.2) ENST00000552072 ENST00000535729
ENST00000431221 ENST00000547005 ENST00000311893(uc010sxc.2) ENST00000539580(uc009zuy.3)
ENST00000392807(uc001tnc.4) ENST00000539593(uc010sxa.1) ENST00000535405
ENST00000544493 ENST00000540154 ENST00000538193 ENST00000338291
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ISCU (NM_213595) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ISCU | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISCU |
Additional cDNA sequence: AK000574.1 AK057251.1 AK293202.1 AK297862.1 AY009127.1 AY009128.1 BC003522.1 BC011906.2 BC061903.1 EU329002.1 U47101.1 13 DOTS entries: DT.101984346 DT.100822291 DT.417830 DT.100822286 DT.100822288 DT.95160742 DT.75143425 DT.91756816 DT.100822293 DT.95160763 DT.97847991 DT.100822285 DT.408935 24/368 AceView cDNA sequences (see all 368): AA453054 AW021471 CR622204 BQ002528 BM714956 CR612054 BM666465 CB160615 AA934707 CR607729 CR604295 BM691103 AI287714 AK022758 AL702163 AW021398 BM695297 CA432796 BI491043 AL702164 CR621989 CB161236 AI866825 BU732035
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ISCU (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | - | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | - | | | | | | - | | - | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | - | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ISCU
|
Expression
for ISCU gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ISCU expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAGCAAAAT
About this image
See ISCU Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ISCU
SOURCE GeneReport for Unigene cluster: Hs.615131
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1Tissue specificity: Detected in heart, liver, skeletal muscle, brain, pancreas, kidney, lung and placenta
SABiosciences Custom PCR Arrays for ISCU
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISCU
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ISCU | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISCU | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISCU | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISCU |
Orthologs
for ISCU gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ISCU gene from 11/44 species (see all 44) About this table
ENSEMBL Gene Tree for ISCU (if available)
TreeFam Gene Tree for ISCU (if available) |
Paralogs
for ISCU gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ISCU gene
ISCU for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ISCU
PGOHUM00000244328 PGOHUM00000260128
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Genomic Variants
for ISCU gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ISCU (108956294 - 108963160 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ISCU: --
Human Gene Mutation Database (HGMD): ISCU
Locus Specific Mutation Databases (LSDB): ISCU
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ISCU gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ISCU for disorders About GeneDecksing
OMIM gene information: 611911
OMIM disorders: 255125
UniProtKB/Swiss-Prot: ISCU_HUMAN, Q9H1K1
Defects in ISCU are the cause of myopathy with exercise intolerance Swedish type (MEIS) [MIM:255125]; alsoknown as myopathy with deficiency of succinate dehydrogenase and aconitase or myoglobinuria due to abnormal glycolysisor hereditary myopathy with lactic acidosis (HML). This autosomal recessive metabolic disease is characterized bylifelong severe exercise intolerance, in which minor exertion causes fatigue of active muscles, shortness of breath,and cardiac palpitations in association with lactic acidosis. The biochemical phenotype is characterized by adeficiency in mitochondrial iron-sulfur proteins and impaired muscle oxidative metabolism
14  diseases for ISCU: About MalaCardsmyopathy lactic acidosis myopathy with deficiency of iscu sideroblastic anemia
friedreich ataxia colon adenocarcinoma ataxia adenocarcinoma
anemia pneumonia hypoxia tuberculosis
malaria mycobacterium tuberculosis
4 diseases from the University of Copenhagen DISEASES database for ISCU:Friedreich ataxia Sideroblastic anemia Lactic acidosis Myopathy GeneTests: ISCU
Myopathy with Deficiency of ISCU
Human Genome Epidemiology (HuGE) Navigator: ISCU (1 document)
Export disorders for ISCU gene to outside databases
|
Publications
for ISCU gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ISCU gene, integrated from 9 sources (see all 60):
(articles sorted by number of sources associating them with ISCU) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A modular domain of NifU, a nitrogen fixation cluster protein, is highly conserved in evolution. (PubMed id 8875867)1, 2, 3, 9 Hwang D.M.... Liew C.-C. (1996)
- Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells. (PubMed id 11060020)1, 2, 3, 9 Tong W.-H. and Rouault T. (2000)
- Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. (PubMed id 18304497)1, 2, 9 Mochel F.... Haller R.G. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Clinical manifestation and a new ISCU mutation in iro n-sulphur cluster deficiency myopathy. (PubMed id 19567699)1, 9 Kollberg G....Holme E. (2009)
- Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. (PubMed id 16517407)1, 9 Tong W.H. and Rouault T.A. (2006)
- Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect. (PubMed id 18296749)1, 9 Olsson A....Holmberg M. (2008)
- Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly. (PubMed id 16527810)1, 9 Li K....Rouault T.A. (2006)
- Heterotrifunctional chemical cross-linking mass spectr ometry confirms physical interaction between human frataxin and ISU. (PubMed id 22897349)1 Watson H.M....Busenlehner L.S. (2012)
- Identification of a signaling axis HIF-1a/microRNA-210 /ISCU independent of SDH mutation that defines a subgroup of head and neck parag angliomas. (PubMed id 22977270)1 Merlo A....Chiara M.D. (2012)
|
External Searches for ISCU gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ISCU gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ISCU gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ISCU gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ISCU | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ISCU |
|
| | |
About This Section
| Patent Information for ISCU gene:
Search GeneIP for patents involving ISCU
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ISCU gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ISCU | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ISCU | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ISCU | | | OriGene Protein Over-expression Lysate for ISCU | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ISCU | | OriGene 3'-UTR Clone for ISCU | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ISCU | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ISCU | | OriGene Custom Protein Services for ISCU | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ISCU | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ISCU | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ISCU | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ISCU | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ISCU | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ISCU |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ISCU |
| |  |  |  |  | | | | | | Recombinant Protein for ISCU |
|
 |
 |
 |
 | | | ISCU Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ISCU |
|  |  |  | | | | Search ThermoFisher Antibodies for ISCU |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ISCU |
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