Aliases for ISCA2 Gene
External Ids for ISCA2 Gene
Previous HGNC Symbols for ISCA2 Gene
Previous GeneCards Identifiers for ISCA2 Gene
The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
GeneCards Summary for ISCA2 Gene
ISCA2 (Iron-Sulfur Cluster Assembly 2) is a Protein Coding gene. Diseases associated with ISCA2 include Multiple Mitochondrial Dysfunctions Syndrome 4 and Multiple Mitochondrial Dysfunctions Syndrome. GO annotations related to this gene include structural molecule activity and iron-sulfur cluster binding.
UniProtKB/Swiss-Prot for ISCA2 Gene
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.