Aliases for ISCA1 Gene
Aliases for ISCA1 Gene
External Ids for ISCA1 Gene
- HGNC: 28660
- Entrez Gene: 81689
- Ensembl: ENSG00000135070
- OMIM: 611006
- UniProtKB: Q9BUE6
Previous HGNC Symbols for ISCA1 Gene
- HBLD2
Previous GeneCards Identifiers for ISCA1 Gene
- GC09M088070
- GC09M088879
- GC09M058702
Summaries for ISCA1 Gene
-
ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]).[supplied by OMIM, Mar 2008]
GeneCards Summary for ISCA1 Gene
ISCA1 (Iron-Sulfur Cluster Assembly 1) is a Protein Coding gene. GO annotations related to this gene include structural molecule activity and iron-sulfur cluster binding.
UniProtKB/Swiss-Prot for ISCA1 Gene
-
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ISCA1 Gene
Genomics for ISCA1 Gene
Regulatory Elements for ISCA1 Gene
Enhancers for ISCA1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09G086287 | 1.1 | Ensembl ENCODE | 0.7 | -4.1 | -4120 | 0.4 | ATF1 ARID4B ZNF2 THRB RAD21 ZNF143 CREM THAP11 ZNF654 CEBPB | C9orf153 ISCA1 GC09M086340 |
| GH09G086280 | 1.1 | ENCODE | 0.7 | +0.7 | 743 | 2.8 | HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 | C9orf153 GAS1RR RN7SKP264 GAS1 ZCCHC6 ISCA1 |
| GH09G086284 | 0.7 | ENCODE | 0.7 | -2.1 | -2103 | 1.3 | SMARCE1 LEF1 PKNOX1 TBL1XR1 MTA2 TAL1 REST DPF2 ZNF592 FOXM1 | ZCCHC6 C9orf153 ISCA1 GC09M086340 |
| GH09G086286 | 0.6 | ENCODE | 0.7 | -3.6 | -3562 | 0.1 | TAL1 DPF2 ZNF592 TCF12 ARID1B GATA2 MYNN TRIM24 TRIM28 | ISCA1 GC09M086340 |
| GH09G086337 | 1.1 | Ensembl ENCODE | 0.2 | -56.0 | -55971 | 4.0 | PKNOX1 TBL1XR1 NFIB INSM2 BMI1 ZBTB40 ZNF143 RELB IKZF2 CREM | ZCCHC6 C9orf153 GC09M086340 ISCA1 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ISCA1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ISCA1 Gene
- Chromosome:
- 9
- Start:
- 86,264,546 bp from pter
- End:
- 86,283,102 bp from pter
- Size:
- 18,557 bases
- Orientation:
- Minus strand
Genomic View for ISCA1 Gene
Genes around ISCA1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q21.33 by Ensembl
- 9q21.33 by Entrez Gene
- 9q21.33 by HGNC
ISCA1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ISCA1 Gene
Proteins for ISCA1 Gene
-
Protein details for ISCA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BUE6-ISCA1_HUMAN
- Recommended name:
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- Protein Accession:
- Q9BUE6
- B3KP34
- B4DJI5
- Q8ND75
- Q9BZR2
Protein attributes for ISCA1 Gene
- Size:
- 129 amino acids
- Molecular mass:
- 14179 Da
- Quaternary structure:
-
- Interacts with CRY2, but not with CRY1 (in vitro).
- SequenceCaution:
-
- Sequence=AAG59854.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD39021.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ISCA1 Gene
Post-translational modifications for ISCA1 Gene
Other Protein References for ISCA1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ISCA1
- Invitrogen Antibodies for ISCA1
- antibodies-online Antibodies for ISCA1: See all 19
- Search GeneTex for Antibodies for ISCA1
Protein Products
-
OriGene Purified Proteins for ISCA1
- Search Origene for MassSpec and Protein Over-expression Lysates for ISCA1
- Origene Custom Protein Services for ISCA1
- antibodies-online Proteins for ISCA1: See all 9
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ISCA1
-
Abcam proteins for ISCA1
No data available for DME Specific Peptides for ISCA1 Gene
Domains & Families for ISCA1 Gene
Protein Domains for ISCA1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ISCA1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9BUE6- Family:
-
- Belongs to the HesB/IscA family.
No data available for Gene Families for ISCA1 Gene
Function for ISCA1 Gene
Molecular function for ISCA1 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005198 | structural molecule activity | IEA | -- |
| GO:0008198 | ferrous iron binding | IBA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0051536 | iron-sulfur cluster binding | IEA | -- |
| GO:0051537 | 2 iron, 2 sulfur cluster binding | IBA | -- |
Phenotypes for ISCA1 Gene
- MGI mutant phenotypes for ISCA1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ISCA1:
Animal Models for ISCA1 Gene
- MGI Knock Outs for ISCA1:
-
- Isca1 tm1b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ISCA1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ISCA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ISCA1 gene
- Search ViGene Biosciences for ISCA1
CRISPR Products
-
OriGene CRISPR knockouts for ISCA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ISCA1
- GenScript: Design CRISPR guide RNA sequences for ISCA1
miRNA for ISCA1 Gene
- miRTarBase miRNAs that target ISCA1
-
- hsa-mir-181c-5p (MIRT047223)
- hsa-mir-4451 (MIRT487940)
- hsa-mir-3132 (MIRT487941)
- hsa-mir-197-5p (MIRT487942)
- hsa-mir-6835-5p (MIRT487943)
- hsa-mir-3175 (MIRT487944)
- hsa-mir-8085 (MIRT487945)
- hsa-mir-6731-5p (MIRT487946)
- hsa-mir-2114-5p (MIRT487947)
- hsa-mir-5007-5p (MIRT487948)
- hsa-mir-624-3p (MIRT487949)
- hsa-mir-3152-5p (MIRT563443)
- hsa-mir-4774-3p (MIRT563444)
- hsa-mir-6894-3p (MIRT563445)
- hsa-mir-6514-3p (MIRT563446)
- hsa-mir-661 (MIRT563447)
- hsa-mir-3116 (MIRT563448)
- hsa-mir-6499-3p (MIRT563449)
- hsa-mir-1254 (MIRT563450)
- hsa-mir-583 (MIRT563451)
- hsa-mir-1276 (MIRT563452)
- hsa-mir-4311 (MIRT563453)
miRNA Products
- Search ViGene Biosciences for ISCA1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ISCA1
- Browse OriGene Inhibitory RNA Products For ISCA1
-
ViGene Biosciences ready-to-package AAV shRNAs for ISCA1 gene
Clone Products
-
OriGene ORF clones in human for ISCA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ISCA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ISCA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ISCA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for ISCA1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ISCA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ISCA1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ISCA1 Gene
Localization for ISCA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ISCA1 Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005759 | mitochondrial matrix | TAS,IBA | -- |
Pathways & Interactions for ISCA1 Gene
No Data Available
Interacting Proteins for ISCA1 Gene
Selected Interacting proteins:
Q9BUE6-ISCA1_HUMAN
ENSP00000365159
for ISCA1 Gene via
MINT
STRING
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016226 | iron-sulfur cluster assembly | IBA | -- |
| GO:0044281 | small molecule metabolic process | TAS | -- |
| GO:0097428 | protein maturation by iron-sulfur cluster transfer | IBA,IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ISCA1 Gene
Transcripts for ISCA1 Gene
mRNA/cDNA for ISCA1 Gene
- (1) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (307) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ISCA1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ISCA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ISCA1
- GenScript: Design CRISPR guide RNA sequences for ISCA1
miRNA Products
- Search ViGene Biosciences for ISCA1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ISCA1
- Browse OriGene Inhibitory RNA Products For ISCA1
-
ViGene Biosciences ready-to-package AAV shRNAs for ISCA1 gene
Clone Products
-
OriGene ORF clones in human for ISCA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ISCA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ISCA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ISCA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: |
Expression for ISCA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
This gene is overexpressed in Ovary (11.0) and Adrenal (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ISCA1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ISCA1 Gene:
ISCA1SOURCE GeneReport for Unigene cluster for ISCA1 Gene:
Hs.449291mRNA Expression by UniProt/SwissProt for ISCA1 Gene:
Q9BUE6-ISCA1_HUMAN
Tissue specificity:
Detected in cerebellum, kidney and heart.
Evidence on tissue expression from TISSUES for ISCA1 Gene
- Nervous system(5)
- Kidney(2.3)
Primer Products
-
OriGene qPCR primer pairs and template standards for ISCA1
-
OriGene qPCR primer pairs for ISCA1
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ISCA1 Gene
Orthologs for ISCA1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ISCA1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | AK157302 35 |
|
OneToMany | |
| Isca1 34 16 35 |
|
||||
| cow (Bos Taurus) |
Mammalia | ISCA1 34 35 |
|
||
| -- 35 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | ISCA1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ISCA1 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Isca1 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ISCA1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ISCA1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ISCA1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | isca1 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.9646 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | isca1 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002730 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | l(1)G0136 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | CELE_Y39B6A.3 34 |
|
||
| Y39B6A.3 35 |
|
OneToOne | |||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F18150g 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ISA1 35 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT2G16710 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0105800 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5203 35 |
|
OneToOne |
- Species where no ortholog for ISCA1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ISCA1 Gene
(1) SIMAP similar genes for ISCA1 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for ISCA1 Gene
No data available for Paralogs for ISCA1 Gene
Variants for ISCA1 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000029020 | -- | 86,278,649(+) | TGGGT(C/G)ACAGA | intron-variant | |
| rs1000409192 | -- | 86,275,532(+) | GAAGG(A/G)CATGA | intron-variant | |
| rs1000504617 | -- | 86,270,174(+) | GAGAA(A/C)ATTTT | intron-variant | |
| rs1000615380 | -- | 86,267,315(+) | ATTAA(A/G)TCACC | intron-variant | |
| rs1000620636 | -- | 86,270,512(+) | AGTTC(A/T)ACCAT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1041191 | CNV | gain | 25217958 |
| nsv972770 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
54.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.21;
39.94% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ISCA1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ISCA1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ISCA1 Gene
Disorders for ISCA1 Gene
Relevant External Links for ISCA1
No disorders were found for ISCA1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ISCA1 Gene
Publications for ISCA1 Gene
- hIscA: a protein implicated in the biogenesis of iron-sulfur clusters. (PMID: 15262227) Cozar-Castellano I. … Avila J. (Biochim. Biophys. Acta 2004) 2 3 4 22 64
- The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation. (PMID: 22323289) Sheftel A.D. … Lill R. (Mol. Biol. Cell 2012) 2 3 4 64
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 46 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
Products for ISCA1 Gene
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- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Custom Antibody Services
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- Custom Assay Services
- OriGene Purified Proteins for ISCA1
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- OriGene qPCR primer pairs and template standards for ISCA1
- OriGene qPCR primer pairs for ISCA1
- OriGene CRISPR knockouts for ISCA1
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for ISCA1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ISCA1
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- GenScript: Design CRISPR guide RNA sequences for ISCA1
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- CloneReady with Over 120,000 Genes
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- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
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- Sino Biological Human cDNA Clone for ISCA1
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- Novus Biologicals Antibodies for ISCA1
- Novus Biologicals proteins and lysates for ISCA1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam proteins for ISCA1
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for ISCA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for ISCA1: See all 19
- Search antibodies-online for kits
- antibodies-online Proteins for ISCA1: See all 9
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for ISCA1
- Search GeneTex for Proteins for ISCA1
- ViGene Biosciences adenoviral particle packaged cDNA for ISCA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ISCA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ISCA1 gene
- Search ViGene Biosciences for ISCA1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ISCA1
- VectorBuilder custom plasmid, inducible vectors for ISCA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ISCA1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ISCA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
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