Aliases for IRX1 Gene
External Ids for IRX1 Gene
Previous GeneCards Identifiers for IRX1 Gene
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011]
GeneCards Summary for IRX1 Gene
IRX1 (Iroquois Homeobox 1) is a Protein Coding gene. Diseases associated with IRX1 include Pulmonary Immaturity and Griscelli Syndrome, Type 3. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is IRX3.