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Aliases for IRS3P Gene

Aliases for IRS3P Gene

  • Insulin Receptor Substrate 3, Pseudogene 2 3
  • Insulin Receptor Substrate 3-Like 2
  • IRS3L 3

External Ids for IRS3P Gene

Previous HGNC Symbols for IRS3P Gene

  • IRS3L

Previous GeneCards Identifiers for IRS3P Gene

  • GC07P099523
  • GC07P100163

Summaries for IRS3P Gene

GeneCards Summary for IRS3P Gene

IRS3P (Insulin Receptor Substrate 3, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IRS3P Gene

Genomics for IRS3P Gene

Genomic Location for IRS3P Gene

100,570,131 bp from pter
100,571,401 bp from pter
1,271 bases
Plus strand

Genomic View for IRS3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for IRS3P Gene

No data available for Regulatory Elements for IRS3P Gene

Proteins for IRS3P Gene

Post-translational modifications for IRS3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for IRS3P Gene

Domains & Families for IRS3P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IRS3P Gene

Function for IRS3P Gene

genes like me logo Genes that share phenotypes with IRS3P: view

Animal Models for IRS3P Gene

MGI Knock Outs for IRS3P:

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , miRNA , Transcription Factor Targets and HOMER Transcription for IRS3P Gene

Localization for IRS3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IRS3P Gene

Pathways & Interactions for IRS3P Gene

SuperPathways for IRS3P Gene

No Data Available

Interacting Proteins for IRS3P Gene

Gene Ontology (GO) - Biological Process for IRS3P Gene


No data available for Pathways by source and SIGNOR curated interactions for IRS3P Gene

Drugs & Compounds for IRS3P Gene

No Compound Related Data Available

Transcripts for IRS3P Gene

mRNA/cDNA for IRS3P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IRS3P Gene

No ASD Table

Relevant External Links for IRS3P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IRS3P Gene

mRNA expression in normal human tissues for IRS3P Gene

genes like me logo Genes that share expression patterns with IRS3P: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IRS3P Gene

Orthologs for IRS3P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for IRS3P Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Irs3 16
Species with no ortholog for IRS3P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IRS3P Gene

Gene Tree for IRS3P (if available)
Gene Tree for IRS3P (if available)

Paralogs for IRS3P Gene

No data available for Paralogs for IRS3P Gene

Variants for IRS3P Gene

Relevant External Links for IRS3P Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IRS3P Gene

Disorders for IRS3P Gene

genes like me logo Genes that share disorders with IRS3P: view

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IRS3P Gene

Publications for IRS3P Gene

  1. Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans. (PMID: 12488959) BjAPrnholm M. … Zierath J.R. (Diabetologia 2002) 2 67
  2. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. (PMID: 9799793) Gloeckner G. … Rosenthal A. (Genome Res. 1998) 2 67
  3. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene. (PMID: 22635093) Melkersson K. … Persson B. (Neuro Endocrinol. Lett. 2012) 67
  4. Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity. (PMID: 20226764) Kabuta T. … Takahashi S. (Biochem. Biophys. Res. Commun. 2010) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for IRS3P Gene

Sources for IRS3P Gene

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