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Aliases for IRS3P Gene

Aliases for IRS3P Gene

  • Insulin Receptor Substrate 3, Pseudogene 2 3 5
  • Insulin Receptor Substrate 3-Like 2
  • IRS3L 3

External Ids for IRS3P Gene

Previous HGNC Symbols for IRS3P Gene

  • IRS3L

Previous GeneCards Identifiers for IRS3P Gene

  • GC07P099523
  • GC07P100163

Summaries for IRS3P Gene

GeneCards Summary for IRS3P Gene

IRS3P (Insulin Receptor Substrate 3, Pseudogene) is a Pseudogene. Among its related pathways are Adipogenesis.

Additional gene information for IRS3P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IRS3P Gene

Genomics for IRS3P Gene

GeneHancer (GH) Regulatory Elements for IRS3P Gene

Promoters and enhancers for IRS3P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I100566 Enhancer 1.4 Ensembl ENCODE dbSUPER 550.8 -0.7 -685 5.9 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 KLF13 IRS3P SAP25 TMEM225B GPC2 MBLAC1 ENSG00000274272 AGFG2
GH07I100538 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13 -25.5 -25518 12.6 CLOCK MLX DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC SSRP1 AGFG2 SAP25 PPP1R35 SRRT ZSCAN25 LRCH4 GIGYF1 AP4M1 MEPCE FBXO24
GH07I100427 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 11.1 -136.9 -136932 10.8 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PPP1R35 MEPCE PIR54054 ZCWPW1 ZSCAN25 TRIM4 SRRT GIGYF1 ZNF3 PILRA
GH07I100823 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.8 +257.0 256985 6.7 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 EPHB4 SLC12A9 ZNF3 TRIM4 GIGYF1 SRRT STAG3L5P ACHE PCOLCE ENSG00000242798
GH07I100438 Enhancer 1.6 FANTOM5 Ensembl ENCODE 11.6 -127.3 -127309 8 HDGF PKNOX1 MLX ARNT ARID4B DMAP1 YY1 SLC30A9 POLR2B ZNF766 PILRA C7orf61 TSC22D4 NYAP1 IRS3P SAP25 FBXO24 LRCH4 GPC2 PVRIG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IRS3P on UCSC Golden Path with GeneCards custom track

Genomic Locations for IRS3P Gene

Genomic Locations for IRS3P Gene
chr7:100,570,131-100,571,401
(GRCh38/hg38)
Size:
1,271 bases
Orientation:
Plus strand
chr7:100,162,878-100,167,751
(GRCh37/hg19)

Genomic View for IRS3P Gene

Genes around IRS3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IRS3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IRS3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IRS3P Gene

Proteins for IRS3P Gene

Post-translational modifications for IRS3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for IRS3P Gene

Domains & Families for IRS3P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IRS3P Gene

Function for IRS3P Gene

Phenotypes From GWAS Catalog for IRS3P Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IRS3P Gene

Localization for IRS3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for IRS3P Gene

Pathways & Interactions for IRS3P Gene

SuperPathways for IRS3P Gene

SuperPathway Contained pathways
1 Adipogenesis
genes like me logo Genes that share pathways with IRS3P: view

Pathways by source for IRS3P Gene

1 BioSystems pathway for IRS3P Gene

Interacting Proteins for IRS3P Gene

Gene Ontology (GO) - Biological Process for IRS3P Gene

None

No data available for SIGNOR curated interactions for IRS3P Gene

Drugs & Compounds for IRS3P Gene

No Compound Related Data Available

Transcripts for IRS3P Gene

mRNA/cDNA for IRS3P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IRS3P Gene

No ASD Table

Relevant External Links for IRS3P Gene

GeneLoc Exon Structure for
IRS3P
ECgene alternative splicing isoforms for
IRS3P

Expression for IRS3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IRS3P Gene

NURSA nuclear receptor signaling pathways regulating expression of IRS3P Gene:

IRS3P
genes like me logo Genes that share expression patterns with IRS3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IRS3P Gene

Orthologs for IRS3P Gene

Evolution for IRS3P Gene

ENSEMBL:
Gene Tree for IRS3P (if available)
TreeFam:
Gene Tree for IRS3P (if available)

No data available for Orthologs for IRS3P Gene

Paralogs for IRS3P Gene

No data available for Paralogs for IRS3P Gene

Variants for IRS3P Gene

Additional Variant Information for IRS3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IRS3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IRS3P Gene

Disorders for IRS3P Gene

No disorders were found for IRS3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IRS3P Gene

Publications for IRS3P Gene

  1. Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans. (PMID: 12488959) Björnholm M … Zierath JR (Diabetologia 2002) 2 3 58
  2. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. (PMID: 9799793) Glöckner G … Rosenthal A (Genome research 1998) 2 3 58
  3. Evolution of the vertebrate insulin receptor substrate (Irs) gene family. (PMID: 28645244) Al-Salam A … Irwin DM (BMC evolutionary biology 2017) 3 58
  4. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene. (PMID: 22635093) Melkersson K … Persson B (Neuro endocrinology letters 2012) 3 58
  5. Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity. (PMID: 20226764) Kabuta T … Takahashi S (Biochemical and biophysical research communications 2010) 3 58

Products for IRS3P Gene

Sources for IRS3P Gene

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