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Aliases for IRS3P Gene

Aliases for IRS3P Gene

  • Insulin Receptor Substrate 3, Pseudogene 2 3 5
  • Insulin Receptor Substrate 3-Like 2
  • IRS3L 3

External Ids for IRS3P Gene

Previous HGNC Symbols for IRS3P Gene

  • IRS3L

Previous GeneCards Identifiers for IRS3P Gene

  • GC07P099523
  • GC07P100163

Summaries for IRS3P Gene

GeneCards Summary for IRS3P Gene

IRS3P (Insulin Receptor Substrate 3, Pseudogene) is a Pseudogene. Among its related pathways are Adipogenesis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IRS3P Gene

Genomics for IRS3P Gene

Regulatory Elements for IRS3P Gene

Enhancers for IRS3P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F100538 1.8 FANTOM5 Ensembl ENCODE 12.9 -25.5 -25518 12.6 CREB3L1 MLX DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 SSRP1 SAP25 PILRA IRS3P FBXO24 LRCH4 NYAP1 TSC22D4 C7orf61 PCOLCE PCOLCE-AS1
GH07F100438 1.7 FANTOM5 Ensembl ENCODE 11.6 -127.3 -127309 8.0 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B DMAP1 YY1 SLC30A9 FOS PILRA ZNF789 C7orf61 TSC22D4 NYAP1 ENSG00000242798 IRS3P SAP25 FBXO24 LRCH4
GH07F100835 1.7 FANTOM5 Ensembl ENCODE 10.7 +266.7 266705 2.5 PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 CBX5 EPHB4 MIR6875 RN7SL750P RN7SL416P GIGYF1 STAG3L5P NYAP1 ENSG00000242798 MBLAC1 SAP25
GH07F100427 1.2 ENCODE 11.1 -136.9 -136932 10.8 CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 ZSCAN25 PILRA ZNF655 PCOLCE STAG3L5P GIGYF1 AP4M1 PPP1R35 EPHB4 MBLAC1
GH07F100831 1.2 ENCODE 10.7 +261.7 261713 1.6 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC EPHB4 AGFG2 NYAP1 MBLAC1 FBXO24 LRCH4 SAP25 IRS3P ACHE TRIM4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IRS3P on UCSC Golden Path with GeneCards custom track

Promoters for IRS3P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001050172 -131 801 PKNOX1 ARNT MLX ZFP64 ARID4B FEZF1 DMAP1 ZNF2 ZNF766 CBX5

Genomic Location for IRS3P Gene

Chromosome:
7
Start:
100,570,131 bp from pter
End:
100,571,401 bp from pter
Size:
1,271 bases
Orientation:
Plus strand

Genomic View for IRS3P Gene

Genes around IRS3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IRS3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IRS3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IRS3P Gene

Proteins for IRS3P Gene

Post-translational modifications for IRS3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for IRS3P Gene

Domains & Families for IRS3P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IRS3P Gene

Function for IRS3P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IRS3P Gene

Localization for IRS3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IRS3P Gene

Pathways & Interactions for IRS3P Gene

SuperPathways for IRS3P Gene

SuperPathway Contained pathways
1 Adipogenesis
genes like me logo Genes that share pathways with IRS3P: view

Pathways by source for IRS3P Gene

1 BioSystems pathway for IRS3P Gene

Interacting Proteins for IRS3P Gene

Gene Ontology (GO) - Biological Process for IRS3P Gene

None

No data available for SIGNOR curated interactions for IRS3P Gene

Transcripts for IRS3P Gene

mRNA/cDNA for IRS3P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IRS3P Gene

No ASD Table

Relevant External Links for IRS3P Gene

GeneLoc Exon Structure for
IRS3P
ECgene alternative splicing isoforms for
IRS3P

Expression for IRS3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IRS3P Gene

NURSA nuclear receptor signaling pathways regulating expression of IRS3P Gene:

IRS3P
genes like me logo Genes that share expression patterns with IRS3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IRS3P Gene

Orthologs for IRS3P Gene

Evolution for IRS3P Gene

ENSEMBL:
Gene Tree for IRS3P (if available)
TreeFam:
Gene Tree for IRS3P (if available)

No data available for Orthologs for IRS3P Gene

Paralogs for IRS3P Gene

No data available for Paralogs for IRS3P Gene

Variants for IRS3P Gene

Relevant External Links for IRS3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IRS3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IRS3P Gene

Disorders for IRS3P Gene

No disorders were found for IRS3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IRS3P Gene

Publications for IRS3P Gene

  1. Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans. (PMID: 12488959) BjAPrnholm M. … Zierath J.R. (Diabetologia 2002) 2 3 64
  2. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. (PMID: 9799793) Gloeckner G. … Rosenthal A. (Genome Res. 1998) 2 3 64
  3. Evidence for a negative association between schizophrenia and a polymorphism in the insulin receptor substrate-3 (IRS-3) gene. (PMID: 22635093) Melkersson K. … Persson B. (Neuro Endocrinol. Lett. 2012) 3 64
  4. Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity. (PMID: 20226764) Kabuta T. … Takahashi S. (Biochem. Biophys. Res. Commun. 2010) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for IRS3P Gene

Sources for IRS3P Gene

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