IRGM Gene
protein-coding GIFtS: 49
GCID: GC05P150208
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immunity-related GTPase family, M(Previous names: immunity-related GTPase family, M1 )
(Previous symbol: IRGM1)
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Aliases
for IRGM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Immunity-Related GTPase Family, M1 2 | | Interferon-Inducible Protein 12 3 | | IFI11 2 3 5 | | LPS-Stimulated RAW 264.7 Macrophage Protein 47 Homolog2 3 | | LRG471 2 3 5 | | Immunity-Related GTPase Family M Protein2 | | IRGM11 2 3 | | LRG-47-Like Protein2 | | LRG-471 2 3 | | EC 3.6.5.-3 | | Immunity-Related GTPase Family, M11 2 | | Immunity-Related GTPase Family M Protein 13 |
Export aliases for IRGM gene to outside databasesPrevious GC identifer: GC05P145371 |
Summaries
for IRGM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IRGM:
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innateimmune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affectthe normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.(providedby RefSeq, Oct 2010)
UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4Function: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions ininnate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production andprevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity)
Gene Wiki entry for IRGM
|
Genomic Views
for IRGM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_029289.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IRGM gene promoter:
STAT1 SREBP-1c STAT1beta NF-kappaB STAT1alpha SREBP-1b SREBP-1a POU2F1 POU2F1a NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for IRGM
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRGM |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q33.1 Ensembl cytogenetic band: 5q33.1 HGNC cytogenetic band: 5q33.1IRGM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P150208: view genomic region
(about GC identifiers)
Start:
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150,226,085 bp from pter |
End:
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150,280,298 bp from pter |
Size:
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54,214 bases |
Orientation:
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plus strand |
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Proteins
for IRGM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4 (See
protein sequence)Recommended Name: Immunity-related GTPase family M protein Size: 181 amino acids; 20142 Da
Subcellular location: Golgi apparatus membrane (By similarity). Cell membrane (By similarity). Cytoplasmic vesicle,phagosome membrane (By similarity). Cytoplasmic vesicle, autophagosome membrane (By similarity). Cell projection,phagocytic cup (By similarity). Note=Behaves like an integral membrane protein (By similarity). Recruited to theplasma membrane around forming phagocytic cups, it remains associated with maturing autophagosomes (By similarity).Preferentially associated with cis- and medial-Golgi (By similarity)
Miscellaneous: Depletion of IRGM by siRNA favors mycobacteria survival in macrophages
Miscellaneous: There is a huge difference in terms of sequence and regulation of expression compared to the mouseortholog and hence, the function might be slightly different (PubMed:16277747)
Sequence caution: Sequence=AAI28169.1; Type=Erroneous initiation; Sequence=EAW61704.1; Type=Erroneous initiation;
Secondary accessions: B3VEX0Explore the universe of human proteins at neXtProt for IRGM: NX_A1A4Y4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A1A4Y4
IRGM Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001139277.1
ENSEMBL proteins: ENSP00000428220 ENSP00000429819
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
IRGM for ontologies About GeneDecksing
IRGM Antibody Products:
Assay Products for IRGM: |
Protein
Domains /
Families
for IRGM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IRGM for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A1A4Y4ProtoNet protein and cluster: A1A4Y4 UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4Similarity: Belongs to the interferon-inducible GTPase family |
Function
for IRGM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4Function: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions ininnate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production andprevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity)Induction: Not up-regulated by IFNG/IFN-gammaEnzyme Number (IUBMB): EC 3.6.5.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRGM |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005525 | GTP binding |
IEA | -- | | GO:0016817 | hydrolase activity, acting on acid anhydrides |
IEA | -- |
IRGM for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Irgm1tm1Gat for IRGM
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Irgm1):
IRGM for phenotypes About GeneDecksing
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Pathways & Interactions
for IRGM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Leishmaniasis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for IRGM):
IRGM for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IRGM
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
IRGM for ontologies About GeneDecksing
|
Drugs & Compounds
for IRGM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IRGM
Search CenterWatch for drugs/clinical trials and news about IRGM
|
Transcripts
for IRGM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IRGM gene: NM_001145805.1 Unigene Clusters for IRGM: Immunity-related GTPase family, M Hs.519680 , Hs.652148 [show with all ESTs]Unigene Representative Sequences: BC038539, EU7426192 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000522154(uc010jhk.3) ENST00000520549
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IRGM (NM_001145805) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IRGM | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRGM |
Additional cDNA sequence: BC128167.1 BC128168.1 EU742619.1 1 DOTS entry: DT.95179447 2 AceView cDNA sequences: BC038539 BI764111
GeneLoc Exon Structure
|
Expression
for IRGM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IRGM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACCTCAGCA
About this image
Genevestigator expression for IRGM
SOURCE GeneReport for Unigene clusters: Hs.519680 Hs.652148
UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4Tissue specificity: Widely expressed (at protein level). Expressed in several tissues including colon, small bowel andperipheral blood leukocytes
SABiosciences Expression via Pathway-Focused PCR Arrays including IRGM:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IRGM
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IRGM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IRGM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRGM | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRGM |
Orthologs
for IRGM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IRGM gene from 3/7 species (see all 7) About this table
ENSEMBL Gene Tree for IRGM (if available)
TreeFam Gene Tree for IRGM (if available) |
Paralogs
for IRGM gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IRGM gene
- IRGC2
IRGM for paralogs About GeneDecksing
|
Genomic Variants
for IRGM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IRGM (150226085 - 150280298 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for IRGM
3 CNVs: 36358 3580 36357
Human Gene Mutation Database (HGMD): IRGM
Locus Specific Mutation Databases (LSDB): IRGM
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IRGM |
|
Disorders
/ Diseases
for IRGM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IRGM for disorders About GeneDecksing
OMIM gene information: 608212
OMIM disorders: 607948
UniProtKB/Swiss-Prot: IRGM_HUMAN, A1A4Y4
Defects in IRGM are the cause of susceptibility to inflammatory bowel disease type 19 (IBD19) [MIM:612278]. Achronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohndisease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from themouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural anddiscontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, inulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas andgranulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints
11  diseases for IRGM: About MalaCardsmycobacterium tuberculosis, protection against tuberculosis, protection against crohn's disease tuberculosis
mycobacterium tuberculosis ankylosing spondylitis inflammatory bowel disease ulcerative colitis
spondylitis celiac disease toxoplasmosis
3 diseases from the University of Copenhagen DISEASES database for IRGM:Crohn's disease Ulcerative colitis Tuberculosis Human Genome Epidemiology (HuGE) Navigator: IRGM (25 documents)
Export disorders for IRGM gene to outside databases
|
Publications
for IRGM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IRGM gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with IRGM) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. (PubMed id 19174780)1, 2 Weersma R.K....Vermeire S. (2009)
- Death and resurrection of the human IRGM gene. (PubMed id 19266026)1, 2 Bekpen C.... Eichler E.E. (2009)
- Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. (PubMed id 17554261)1, 2 Parkes M....Mathew C.G. (2007)
- Human IRGM induces autophagy to eliminate intracellular mycobacteria. (PubMed id 16888103)1, 2 Singh S.B....Deretic V. (2006)
- The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. (PubMed id 16277747)1, 2 Bekpen C....Howard J.C. (2005)
- Immune control of tuberculosis by IFN-gamma-inducible LRG-47. (PubMed id 14576437)1, 3 MacMicking J.D....McKinney J.D. (2003)
- Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family. (PubMed id 7561525)1, 3 Sorace J.M....Drysdale B.E. (1995)
- Autophagy gene variant IRGM -261T contributes to prot ection from tuberculosis caused by Mycobacterium tuberculosis but not by M. afr icanum strains. (PubMed id 19750224)1, 9 Intemann C.D....Meyer C.G. (2009)
- Mutations in IRGM are associated with more frequent ne ed for surgery in patients with ileocolonic Crohn's disease. (PubMed id 22228152)1 Sehgal R....Koltun W.A. (2012)
- IRGM gene polymorphisms and risk of gastric cancer. (PubMed id 22713085)1 Burada F....Saftoiu A. (2012)
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External Searches for IRGM gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IRGM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IRGM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IRGM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IRGM | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IRGM gene:
Search GeneIP for patents involving IRGM
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IRGM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for IRGM | | OriGene shRNA RFP for IRGM | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IRGM | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IRGM | | | OriGene Protein Over-expression Lysate for IRGM | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IRGM | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRGM | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IRGM | | OriGene Custom Protein Services for IRGM | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IRGM | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IRGM | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRGM | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IRGM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRGM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IRGM |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRGM |
|  |  |  | | | | ThermoFisher Antibodies for IRGM |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRGM |
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