IRF9 Gene
protein-coding GIFtS: 60
GCID: GC14P024630
|
|
interferon regulatory factor 9(Previous names: interferon-stimulated transcription factor 3, gamma (48kD),...)
(Previous symbol: ISGF3G)
| |
Aliases
for IRF9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Interferon Regulatory Factor 91 2 | | IRF-92 3 | | ISGF3G1 2 3 5 | | IFN-Alpha-Responsive Transcription Factor Subunit2 3 | | Interferon-Stimulated Transcription Factor 3, Gamma (48kD)1 2 | | ISGF-3 Gamma2 3 | | Interferon-Stimulated Transcription Factor 3, Gamma 48kDa1 2 | | ISGF3 P48 Subunit2 3 | | Interferon-Stimulated Gene Factor 3 Gamma2 3 | | ISGF32 5 | | Transcriptional Regulator ISGF3 Subunit Gamma2 3 | | P481 |
Export aliases for IRF9 gene to outside databasesPrevious GC identifers: GC14P023702 GC14P023690 GC14P004745 |
Summaries
for IRF9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: IRF9_HUMAN, Q00978Function: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Followingtype I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosinephosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complextermed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE)to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state
Gene Wiki entry for IRF9
|
Genomic Views
for IRF9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IRF9 gene promoter:
AML1a STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for IRF9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRF9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q11.2 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q11.2IRF9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P024630: view genomic region
(about GC identifiers)
Start:
|
24,630,262 bp from pter |
End:
|
24,635,774 bp from pter |
Size:
|
5,513 bases |
Orientation:
|
plus strand |
|
Proteins
for IRF9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IRF9_HUMAN, Q00978 (See
protein sequence)Recommended Name: Interferon regulatory factor 9 Size: 393 amino acids; 43696 Da
Subunit: Interacts with STAT2 in the cytoplasm. Forms a complex with heterodimer STAT1/STAT2
Subcellular location: Cytoplasm. Nucleus. Note=Translocated into the nucleus upon activation by IFN-alpha/beta
Secondary accessions: D3DS61Explore the universe of human proteins at neXtProt for IRF9: NX_Q00978
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q00978
IRF9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006075.3
ENSEMBL proteins: ENSP00000380073 ENSP00000453534 ENSP00000453974 ENSP00000453540 ENSP00000454095 ENSP00000454078 ENSP00000313529 Reactome Protein details: Q00978
Human Recombinant Protein Products for IRF9:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
IRF9 for ontologies About GeneDecksing
IRF9 Antibody Products:
Assay Products for IRF9: |
Protein
Domains /
Families
for IRF9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IRF9 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q00978ProtoNet protein and cluster: Q00978 1 Blocks protein family: IPB001346 Interferon regulatory factor
UniProtKB/Swiss-Prot: IRF9_HUMAN, Q00978Similarity: Belongs to the IRF familySimilarity: Contains 1 IRF tryptophan pentad repeat DNA-binding domain |
Function
for IRF9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: IRF9_HUMAN, Q00978Function: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Followingtype I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosinephosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complextermed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE)to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral stateInduction: By IFN-alpha and IFNB1/IFN-beta Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000975 | regulatory region DNA binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- |
IRF9 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for IRF9:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Irf9):
IRF9 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Irf9tm1Ttg for IRF9
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IRF9 (NM_006084) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IRF9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRF9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRF9 |
|
Pathways & Interactions
for IRF9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune response_IFN gamma signaling pathway | | | 2 | Cytokine Signaling in Immune system | | | 3 | Expression of IFN-induced genes | | | 4 | Interferon gamma signaling | | | 5 | Measles | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for IRF9
2  GeneGo (Thomson Reuters) Pathways for IRF9
2  BioSystems Pathways for IRF9
5/7 
Reactome Pathways for IRF9 (see all 7)
5 
Kegg Pathways (Kegg details for IRF9):
IRF9 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IRF9
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/106 Interacting proteins for IRF9 (Q009781, 2, 3 ENSP000003800734) via UniProtKB, MINT, STRING, and/or I2D (see all 106)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ATN1 | P542592, 3, ENSP000003490764 | MINT-2873996 I2D:
score=1 STRING: ENSP00000349076 | | GFI1B | Q5VTD92, 3, ENSP000003447824 | MINT-2874034 I2D:
score=1 STRING: ENSP00000344782 | | IFNA1 | P015623, ENSP000002769274 | I2D:
score=1 STRING: ENSP00000276927 | | STAT2 | P526301, 3, ENSP000003157684 | EBI-626526,EBI-1546963 I2D:
score=6 STRING: ENSP00000315768 | | IFNAR2 | P485511, 3, ENSP000003439574 | EBI-626526,EBI-958408 I2D:
score=6 STRING: ENSP00000343957 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
IRF9 for ontologies About GeneDecksing
|
Drugs & Compounds
for IRF9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
IRF9 for compounds About GeneDecksing
 Browse Tocris compounds for IRF9
8 Novoseek chemical compound relationships for IRF9 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 2',5'-oligoadenylate |
70.5 |
3 |
9186002 (1), 8836915 (1), 10229853 (1) |
| ifn-alpha |
57.2 |
5 |
11106638 (4) |
| tyrosine |
53 |
17 |
1280824 (4), 9325014 (1), 12704120 (1), 19351818 (1) (see all 14) |
| genistein |
39.8 |
4 |
1280824 (1), 9325014 (1), 17559358 (1) |
| retinoic acid |
34.6 |
6 |
9186002 (3), 9669677 (1), 10435617 (1) |
| cycloheximide |
28.7 |
3 |
11882993 (1), 2118988 (1) |
| adenine |
7.14 |
5 |
1556141 (2), 2118988 (2) |
| oligonucleotide |
6.08 |
2 |
20038197 (1) |
Search CenterWatch for drugs/clinical trials and news about IRF9
|
Transcripts
for IRF9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IRF9 gene: NM_006084.4 Unigene Cluster for IRF9: Interferon regulatory factor 9 Hs.1706 [show with all ESTs]Unigene Representative Sequence: AK29546715 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396864(uc010alj.3) ENST00000557894 ENST00000561342 ENST00000561009
ENST00000560365 ENST00000561415 ENST00000559284 ENST00000560275 ENST00000561412
ENST00000560852 ENST00000324076 ENST00000559863 ENST00000559229 ENST00000560542
ENST00000560311
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IRF9 (NM_006084) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IRF9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRF9 |
Additional cDNA sequence: AK295467.1 AK308347.1 BC035716.2 M87503.1 U92994.1 15 DOTS entries: DT.312276 DT.87013010 DT.91987503 DT.120772566 DT.75161376 DT.100655274 DT.75106086 DT.87016063 DT.120772553 DT.100851623 DT.95236944 DT.99987526 DT.100655271 DT.100712018 DT.95236945 24/410 AceView cDNA sequences (see all 410): CA305900 BM983142 BX378006 BM667985 BM696953 CR609755 BM708088 BG058600 CA308170 BM693231 BM906740 BF516479 BU195806 AI872365 BX477441 CB126210 BM826910 CD171831 BM811285 BI823840 BM807974 BM825698 BC009821 AI828982
GeneLoc Exon Structure
|
Expression
for IRF9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IRF9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTCCAGCCA
About this image
See IRF9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IRF9
SOURCE GeneReport for Unigene cluster: Hs.1706
SABiosciences Expression via Pathway-Focused PCR Arrays including IRF9:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IRF9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IRF9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IRF9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRF9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRF9 |
Orthologs
for IRF9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IRF9 gene from 2/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
---- |
-- |
32(a)31(a) |
1 ↔ many1 ↔ many |
AAWZ02037623(1077-3986) AAWZ02036190(50-8933) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.123082 |
Danio rerio clone RK124A3H10 interferon-stimulated transcription factor 3, gamma 48kDa (ISGF3G) mRNA, complete cds less |
74.29(n) |
|
AY398365.1 |
ENSEMBL Gene Tree for IRF9 (if available)
TreeFam Gene Tree for IRF9 (if available) |
Paralogs
for IRF9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IRF9 gene
- IRF82 IRF22 IRF52 IRF32 IRF12 IRF72 IRF62 IRF42
7 SIMAP similar genes for IRF9 using alignment to 6 protein entries: IRF9_HUMAN (see all proteins):IRF8 IRF4 IRF1 IRF3 IRF2 IRF5
IRF7
IRF9 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for IRF9
PGOHUM00000247509
|
Genomic Variants
for IRF9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IRF9 (24630262 - 24635774 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for IRF9
1 Inversion: 37155 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IRF9 |
|
Disorders
/ Diseases
for IRF9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IRF9 for disorders About GeneDecksing
OMIM gene information: 147574
OMIM disorders: --
20/28  diseases for IRF9 (see all 28): About MalaCardsebola hemorrhagic fever malignant pleural mesothelioma lymphocytic choriomeningitis hemorrhagic fever
transitional cell carcinoma myeloid leukemia kaposi's sarcoma hepatitis b
mumps bronchiolitis squamous cell carcinoma cervical carcinoma
multiple sclerosis hepatitis c stomatitis cervicitis
measles hepatitis sarcoma carcinoma
1 disease from the University of Copenhagen DISEASES database for IRF9:Ebola hemorrhagic fever 9 Novoseek disease relationships for IRF9 gene About this table
Human Genome Epidemiology (HuGE) Navigator: IRF9 (9 documents)
Export disorders for IRF9 gene to outside databases
|
Publications
for IRF9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IRF9 gene, integrated from 9 sources (see all 177):
(articles sorted by number of sources associating them with IRF9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA- binding proteins. (PubMed id 1630447)1, 2, 3, 9 Veals S.A.... Levy D.E. (1992)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation. (PubMed id 11846981)1, 2 Reich N.C. (2002)
- Organization of the genes encoding the human proteasome activators PA28alpha and beta. (PubMed id 10199920)1, 3 McCusker D....Trowsdale J. (1999)
- Viral inhibition of interferon signal transduction. (PubMed id 10702714)1, 2 Cebulla C.M.... Sedmak D.D. (1999)
- Role of ISGF3 in modulating the anti-hepatitis B virus activity of interferon-alpha in vitro. (PubMed id 17559358)1, 9 Zhang Q....Cong X. (2008)
- Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors. (PubMed id 10860992)1, 9 Lau J.F....Horvath C.M. (2000)
- IFN-beta-mediated inhibition of IL-8 expression requires the ISGF3 components Stat1, Stat2, and IRF-9. (PubMed id 18370868)1, 9 Laver T....Benveniste E.N. (2008)
- [A novel molecular mechanism of interferon alpha-regu lated expression of retinoic acid-induced gene G] (PubMed id 20403236)1, 9 Lou Y.J....Tong J.H. (2010)
- Role of metazoan mediator proteins in interferon-responsive transcription. (PubMed id 12509459)1, 9 Lau J.F.... Horvath C.M. (2003)
|
External Searches for IRF9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IRF9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IRF9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IRF9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IRF9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IRF9 gene:
Search GeneIP for patents involving IRF9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IRF9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IRF9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IRF9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IRF9 | | | OriGene Protein Over-expression Lysate for IRF9 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IRF9 | | OriGene 3'-UTR Clone for IRF9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IRF9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for IRF9 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IRF9 | | OriGene Custom Protein Services for IRF9 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IRF9 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IRF9 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRF9 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IRF9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRF9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IRF9 |
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| | | | Search Tocris compounds for IRF9 |
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 | | | IRF9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRF9 |
|  |  |  |  | | | | ThermoFisher Antibodies for IRF9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRF9 |
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