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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IRF2BP2 Gene

protein-coding   GIFtS: 50
GCID: GC01M234740

Interferon Regulatory Factor 2 Binding Protein 2

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Interferon Regulatory Factor 2 Binding Protein 21 2
IRF-2-Binding Protein 22 3
Interferon Regulatory Factor 2-Binding Protein 22
IRF-2BP23

External Ids:    HGNC: 217291   Entrez Gene: 3599482   Ensembl: ENSG000001682647   OMIM: 6153325   UniProtKB: Q7Z5L93   

Export aliases for IRF2BP2 gene to outside databases

Previous GC identifers: GC01U900151 GC01M231827 GC01M231049 GC01M232806 GC01M205232


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IRF2BP2 Gene:
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal
transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding
distinct isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for IRF2BP2 Gene: 
IRF2BP2 (interferon regulatory factor 2 binding protein 2) is a protein-coding gene. Diseases associated with IRF2BP2 include breast cancer. GO annotations related to this gene include metal ion binding. An important paralog of this gene is IRF2BPL.

UniProtKB/Swiss-Prot: I2BP2_HUMAN, Q7Z5L9
Function: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by
histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts
as a coactivator of VEGFA expression in cardiac and skeletal muscle




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IRF2BP2 gene promoter:
         HEN1   CREB   ISGF-3   Zic1   c-Myb   RelA   AP-4   NF-kappaB   NF-kappaB1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIRF2BP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for IRF2BP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRF2BP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.3   Ensembl cytogenetic band:  1q42.3   HGNC cytogenetic band: 1q42.3

IRF2BP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IRF2BP2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M234740:  view genomic region     (about GC identifiers)

Start:
234,740,015 bp from pter      End:
234,745,271 bp from pter
Size:
5,257 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: I2BP2_HUMAN, Q7Z5L9 (See protein sequence)
Recommended Name: Interferon regulatory factor 2-binding protein 2  
Size: 587 amino acids; 61025 Da
Subunit: Interacts with IRF2. Part of a corepressor complex containing IRF2 and IRF2BP1. Interacts with VGLL4
Subcellular location: Cytoplasm. Nucleus
Secondary accessions: B1AM35 B1AM36 Q6P083 Q7Z5L8 Q8N351 Q8WUH8
Alternative splicing: 3 isoforms:  Q7Z5L9-1   Q7Z5L9-2   Q7Z5L9-3   

Explore the universe of human proteins at neXtProt for IRF2BP2: NX_Q7Z5L9

Explore proteomics data for IRF2BP2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation at Ser-360 is required for nuclear targeting
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z5L9

  • IRF2BP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IRF2BP2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001070865.1  NP_892017.2  

    ENSEMBL proteins: 
     ENSP00000355569   ENSP00000355568  

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    Cloud-Clone Corp. Proteins for IRF2BP2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IEA--

    IRF2BP2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR022750 Interferon_reg_fac2-bd1_2_Znf

    Graphical View of Domain Structure for InterPro Entry Q7Z5L9

    ProtoNet protein and cluster: Q7Z5L9

    UniProtKB/Swiss-Prot: I2BP2_HUMAN, Q7Z5L9
    Domain: The C-terminal RING-type zinc finger domain is sufficient for interaction with IRF2
    Similarity: Belongs to the IRF2BP family
    Similarity: Contains 1 RING-type zinc finger


    IRF2BP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: I2BP2_HUMAN, Q7Z5L9
    Function: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by
    histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts
    as a coactivator of VEGFA expression in cardiac and skeletal muscle

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    IRF2BP2 for ontologies           About GeneDecksing


    Phenotypes:
         7 GenomeRNAi human phenotypes for IRF2BP2:
     Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella-containin 
     Decreased viability with pacli  Increased cell number in G2M,   Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for IRF2BP2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IRF2BP2 
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    8/99 QIAGEN miScript miRNA Assays for microRNAs that regulate IRF2BP2 (see all 99):
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    SwitchGear 3'UTR luciferase reporter plasmidIRF2BP2 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IRF2BP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/35 Interacting proteins for IRF2BP2 (Q7Z5L93 ENSP000003555684) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678703I2D: score=1 
    ENSG00000206406P678703I2D: score=1 
    ENSG00000224398P678703I2D: score=1 
    ENSG00000224774P678703I2D: score=1 
    ENSG00000228875P678703I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--

    IRF2BP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IRF2BP2 (I2BP2)

    Search CenterWatch for drugs/clinical trials and news about IRF2BP2 / I2BP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IRF2BP2 gene (2 alternative transcripts): 
    NM_001077397.1  NM_182972.2  

    Unigene Cluster for IRF2BP2:

    Interferon regulatory factor 2 binding protein 2
    Hs.350268  [show with all ESTs]
    Unigene Representative Sequence: NM_182972
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366610(uc009xfw.3 uc001hwf.3) ENST00000366609(uc001hwg.3)
    ENST00000491430
    miRNA
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    8/99 QIAGEN miScript miRNA Assays for microRNAs that regulate IRF2BP2 (see all 99):
    hsa-miR-411* hsa-miR-607 hsa-miR-520e hsa-miR-300 hsa-miR-106a hsa-miR-4272 hsa-miR-1245 hsa-miR-30d
    SwitchGear 3'UTR luciferase reporter plasmidIRF2BP2 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRF2BP2

    Additional mRNA sequence: 

    AK054864.1 AK056930.1 AK299768.1 AK300375.1 AK309579.1 AY278023.1 AY278024.1 BC020516.1 
    BC041989.1 BC053539.1 BC065759.1 

    20 DOTS entries:

    DT.95219517  DT.100826114  DT.454220  DT.95092639  DT.95182970  DT.100741176  DT.91763956  DT.95093418 
    DT.91763967  DT.100826110  DT.100826113  DT.121458712  DT.75173873  DT.95201928  DT.95201922  DT.95201947 
    DT.95299545  DT.97792464  DT.99989440  DT.100044512 

    24/380 AceView cDNA sequences (see all 380):

    CA439551 AW452700 AA811637 CD674626 AL519559 BE408853 AW273584 BI258477 
    BF222614 BU069045 BM836038 BU675168 AW029141 BG913070 BQ878908 AA764910 
    BM828644 CA848152 CB216563 CB147724 AA298477 AA296996 AW236608 AI890678 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for IRF2BP2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b
    SP1:        -     -               
    SP2:              -               
    SP3:                              


    ECgene alternative splicing isoforms for IRF2BP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IRF2BP2 expression in normal human tissues (normalized intensities)      IRF2BP2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAACTGAAG
    IRF2BP2 Expression
    About this image


    IRF2BP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/30 selected tissues (see all 30) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             rectum ; glandular cells   

    See IRF2BP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IRF2BP2

    SOURCE GeneReport for Unigene cluster: Hs.350268
        SABiosciences Custom PCR Arrays for IRF2BP2
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for IRF2BP2 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Irf2bp21 , 5 interferon regulatory factor 2 binding protein 21, 5 86.29(n)1
    88.93(a)1
      8 (74.57 cM)5
    2701101  NM_001164598.11  NP_001158070.11 
     1265882965 
    chicken
    (Gallus gallus)
    Aves IRF2BP21 interferon regulatory factor 2 binding protein 2 78.6(n)
    88.48(a)
      428585  XM_426142.3  XP_426142.3 
    lizard
    (Anolis carolinensis)
    Reptilia IRF2BP26
    Uncharacterized protein
    79(a)
    1 ↔ 1
    1(219997126-219998898)
    African clawed frog
    (Xenopus laevis)
    Amphibia irf2bp2-A2 interferon regulatory factor 2 binding protein 2 79.12(n)    BC044275.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj35c122 wufj35c12 75.08(n)   335866  BC046025.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111386
    --
    24(a)
    1 → many
    X(12463202-12477226)
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2606
    Protein TAG-260, isoform d
    24(a)
    1 → many
    V(13370104-13380189)


    ENSEMBL Gene Tree for IRF2BP2 (if available)
    TreeFam Gene Tree for IRF2BP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IRF2BP2 gene
    IRF2BPL2  IRF2BP12  

    IRF2BP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/198 SNPs in IRF2BP2 are shown (see all 198)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1463765851,2
    --234739525(+) TATCAA/GTAAAG 2 -- ds50010--------
    rs757719431,2
    C--234739566(+) TAAGCT/CTTCCA 2 -- ds50011Minor allele frequency- C:0.01NA 120
    rs2015010801,2
    C--234739595(-) GATTTA/TANNNN 2 -- ds50010--------
    rs602682081,2
    C--234739684(+) TGAGA-/TCTC  
            
    AGTCT
    2 -- ds50010--------
    rs668270901,2
    C--234739685(+) GAGAG-/TCTC  
            
    TCTTT
    2 -- ds50010--------
    rs1158268961,2
    C--234739812(+) TGTCCC/GCTATC 2 -- ds50010--------
    rs1166742781,2
    C--234739831(+) CTTTCC/TGCAGT 2 -- ds50010--------
    rs1861794661,2
    --234739995(+) AAATTA/TAAAAA 2 -- ds50010--------
    rs1903998911,2
    --234740116(+) ATAGCA/GTGATT 2 -- ut310--------
    rs88231,2
    C,F,A,H--234740141(-) AGATAC/TCAACA 2 -- ut3132Minor allele frequency- N:0.00NA EA NS WA CSA 2740

    HapMap Linkage Disequilibrium report for IRF2BP2 (234740015 - 234745271 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for IRF2BP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4921CNV Insertion18451855
    esv25047CNV Loss19812545
    nsv873316CNV Loss21882294
    nsv832914CNV Loss17160897
    nsv468395CNV Loss19166990
    nsv827387CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615332    OMIM disorders: --

    2 diseases for IRF2BP2:    About MalaCards
    breast cancer    


    IRF2BP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IRF2BP2

    Export disorders for IRF2BP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IRF2BP2 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with IRF2BP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel co-repressor molecules for interferon regulatory factor-2. (PubMed id 12799427)1, 2, 3 Childs K.S. and Goodbourn S. (2003)
    2. Genome-wide association of implantable cardioverter-de fibrillator activation with life-threatening arrhythmias. (PubMed id 22247754)1, 4 Murray S.S....Topol E.J. (2012)
    3. Interferon regulatory factor 2 binding protein 2 is a new NFAT1 partner and represses its transcriptional activity. (PubMed id 21576369)1, 2 Carneiro F.R....Viola J.P. (2011)
    4. Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2. (PubMed id 21887377)1, 2 Teng A.C.... Stewart A.F. (2011)
    5. IRF2BP2 is a skeletal and cardiac muscle-enriched isc hemia-inducible activator of VEGFA expression. (PubMed id 20702774)1, 2 Teng A.C....Stewart A.F. (2010)
    6. Biological, clinical and population relevance of 95 l oci for blood lipids. (PubMed id 20686565)1, 4 Teslovich T.M....Kathiresan S. (2010)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Whole-transcriptome sequencing identifies novel IRF2BP 2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma. (PubMed id 23185413)1 Nyquist K.B....Micci F. (2012)
    9. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared wit h bipolar disorder. (PubMed id 22688191)1 Bergen S.E....Sullivan P.F. (2012)
    10. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 359948 HGNC: 21729 AceView: IRF2BP2 Ensembl:ENSG00000168264 euGenes: HUgn359948
    ECgene: IRF2BP2 H-InvDB: IRF2BP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IRF2BP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IRF2BP2 gene:
    Search GeneIP for patents involving IRF2BP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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