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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IRAK1BP1 Gene

protein-coding   GIFtS: 44
GCID: GC06P079577

Interleukin-1 Receptor-Associated Kinase 1 Binding Protein...

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 11 2
AIP702
SIMPL2
ActA Binding Protein 32
Interleukin-1 Receptor-Associated Kinase 1-Binding Protein 12

External Ids:    HGNC: 173681   Entrez Gene: 1347282   Ensembl: ENSG000001462437   OMIM: 6153755   UniProtKB: Q5VVH53   

Export aliases for IRAK1BP1 gene to outside databases

Previous GC identifers: GC06P079527 GC06P079572 GC06P079633 GC06P076770


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IRAK1BP1 Gene: 
IRAK1BP1 (interleukin-1 receptor-associated kinase 1 binding protein 1) is a protein-coding gene. Diseases associated with IRAK1BP1 include quadriplegia.

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5
Function: Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is
required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007299.13  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IRAK1BP1 gene promoter:
         HEN1   GATA-3   FOXJ2 (long isoform)   Chx10   FOXO1a   FOXJ2   E4BP4   GATA-1   GATA-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIRAK1BP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for IRAK1BP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IRAK1BP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14-q15   Ensembl cytogenetic band:  6q14.1   HGNC cytogenetic band: 6q14-q15

IRAK1BP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IRAK1BP1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P079577:  view genomic region     (about GC identifiers)

Start:
79,577,189 bp from pter      End:
79,656,157 bp from pter
Size:
78,969 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5 (See protein sequence)
Recommended Name: Interleukin-1 receptor-associated kinase 1-binding protein 1  
Size: 260 amino acids; 29106 Da
Subunit: Interacts with IRAK1 and RELA. Interacts with HSPA8 and HSPA1 (By similarity)
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)

Explore the universe of human proteins at neXtProt for IRAK1BP1: NX_Q5VVH5

Explore proteomics data for IRAK1BP1 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation at Ser-56 and/or Ser-62 is required for full activity. Phosphorylated on at least one of Ser-235,
    Thr-237, Ser-242 and Thr-247 upon TNF-alpha activation, which favors nuclear translocation (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VVH5

  • IRAK1BP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IRAK1BP1 Protein Expression
    REFSEQ proteins: NP_001010844.1  
    ENSEMBL proteins: 
     ENSP00000358956   ENSP00000475570   ENSP00000475503   ENSP00000475395  

    Human Recombinant Protein Products for IRAK1BP1: 
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    Novus Biologicals IRAK1BP1 Protein
    Novus Biologicals IRAK1BP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for IRAK1BP1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    IRAK1BP1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007497 DUF541

    Graphical View of Domain Structure for InterPro Entry Q5VVH5

    ProtoNet protein and cluster: Q5VVH5

    UniProtKB/Swiss-Prot: IKBP1_HUMAN, Q5VVH5
    Domain: The intrinsically disordered region interacts with HSPA1 and HSPA8 (By similarity)
    Similarity: Belongs to the IRAK1BP1 family


    IRAK1BP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IKBP1_HUMAN, Q5VVH5
    Function: Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is
    required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    IRAK1BP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IRAK1BP1:
     Large cells 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Irak1bp1):
     no phenotypic analysis 

    IRAK1BP1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for IRAK1BP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IRAK1BP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IRAK1BP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IRAK1BP1 

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate IRAK1BP1:
    hsa-miR-3163 hsa-miR-548c-3p hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidIRAK1BP1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of IRAK1BP1

    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of IRAK1BP1 

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    Search LifeMap BioReagents cell lines for IRAK1BP1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRAK1BP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IRAK1BP1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for IRAK1BP1 (Q5VVH53 ENSP000003589564) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IRAK1P516173, ENSP000003589974I2D: score=5 STRING: ENSP00000358997
    RELAQ042063, ENSP000003842734I2D: score=2 STRING: ENSP00000384273
    NFKB1P198383I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007249I-kappaB kinase/NF-kappaB cascade ISS--

    IRAK1BP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IRAK1BP1 (IKBP1)

    Search CenterWatch for drugs/clinical trials and news about IRAK1BP1 / IKBP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IRAK1BP1 gene: 
    NM_001010844.2  

    Unigene Cluster for IRAK1BP1:

    Interleukin-1 receptor-associated kinase 1 binding protein 1
    Hs.656212  [show with all ESTs]
    Unigene Representative Sequence: AK096861
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369940(uc003pim.3 uc010kbg.1 uc003pin.2) ENST00000606868
    ENST00000607739 ENST00000606929
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate IRAK1BP1:
    hsa-miR-3163 hsa-miR-548c-3p hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidIRAK1BP1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IRAK1BP1
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IRAK1BP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IRAK1BP1

    Additional mRNA sequence: 

    AK096861.1 AK098678.1 AK309003.1 BC112253.1 BC112255.1 

    11 DOTS entries:

    DT.97811400  DT.103522  DT.99927665  DT.95322922  DT.95227509  DT.95348514  DT.121387442  DT.100675523 
    DT.75177627  DT.95170404  DT.97858748 

    24/61 AceView cDNA sequences (see all 61):

    AA679673 AA480250 BF513853 BM127007 AI379905 AL521825 AK098678 BM830836 
    AW450696 BX103697 AI761886 BQ435042 AI917638 BX387112 AA405600 BX352843 
    AK096861 AW183916 AA678816 C20908 H81463 BE897882 AI653019 BX403291 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for IRAK1BP1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9
    SP1:                          -                             -     -         
    SP2:                    -     -                                             
    SP3:                    -     -           -     -     -                     
    SP4:                    -                                                   
    SP5:                                                                        


    ECgene alternative splicing isoforms for IRAK1BP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IRAK1BP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATCCCACAT
    IRAK1BP1 Expression
    About this image


    See IRAK1BP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IRAK1BP1

    SOURCE GeneReport for Unigene cluster: Hs.656212
        SABiosciences Custom PCR Arrays for IRAK1BP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IRAK1BP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IRAK1BP1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Irak1bp11 , 5 interleukin-1 receptor-associated kinase 1 binding more1, 5 83.91(n)1
    82.63(a)1
      9 (45.16 cM)5
    650991  NM_022986.41  NP_075362.31 
     828298065 
    chicken
    (Gallus gallus)
    Aves IRAK1BP11 interleukin-1 receptor-associated kinase 1 binding more 65.86(n)
    58.23(a)
      421857  XM_419874.2  XP_419874.2 
    lizard
    (Anolis carolinensis)
    Reptilia IRAK1BP16
    Uncharacterized protein
    54(a)
    1 ↔ 1
    1(199770000-199777616)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.68932 Xenopus laevis transcribed sequence with weak similarity more 74.71(n)    BX851419.1 
    zebrafish
    (Danio rerio)
    Actinopterygii irak1bp11 interleukin-1 receptor-associated kinase 1 binding more 49.04(n)
    41.74(a)
      553809  NM_001020771.1  NP_001018607.1 


    ENSEMBL Gene Tree for IRAK1BP1 (if available)
    TreeFam Gene Tree for IRAK1BP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/689 SNPs in IRAK1BP1 are shown (see all 689)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1900281211,2
    --79575241(+) GATTAA/GGGCCA 1 -- us2k10--------
    rs109435951,2
    C,F,A,H--79575291(+) TTCTTC/GCAATT 1 -- us2k17Minor allele frequency- G:0.23NS NA WA EA 590
    rs109435961,2
    C,A,H--79575292(+) TCTTCC/TAATTA 1 -- us2k15Minor allele frequency- T:0.36NA WA EA 362
    rs1816654461,2
    --79575538(+) CATGTA/GGTCCC 1 -- us2k10--------
    rs1867902011,2
    C--79575571(+) GAGAAC/TGGCGT 1 -- us2k10--------
    rs1916392431,2
    C--79575600(+) TTGCAA/GTGAGC 1 -- us2k10--------
    rs1839679411,2
    --79575602(+) GCAGTA/GAGCCC 1 -- us2k10--------
    rs356353971,2
    C--79575658(+) AAAAA-/A/AA  
            
    TATAT
    1 -- us2k11NA 2
    rs114440871,2
    C--79575667(+) AAAAA-/TAAATA 1 -- us2k1 tfbs3 trp30--------
    rs77608831,2
    C--79575669(+) AAAAAT/AATATA 1 -- us2k1 tfbs3 trp31Minor allele frequency- A:0.00NA 2

    HapMap Linkage Disequilibrium report for IRAK1BP1 (79577189 - 79656157 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for IRAK1BP1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing IRAK1BP1
    DNA2.0 Custom Variant and Variant Library Synthesis for IRAK1BP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615375    OMIM disorders: --

    2 diseases for IRAK1BP1:    About MalaCards
    quadriplegia    


    IRAK1BP1 for disorders           About GeneDecksing


    Export disorders for IRAK1BP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IRAK1BP1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with IRAK1BP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SIMPL is a tumor necrosis factor-specific regulator of nuclear factor-kappaB activity. (PubMed id 11096118)1, 2, 3 Vig E....Harrington M.A. (2001)
    2. Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription. (PubMed id 17079333)1 Luo Y....Harrington M.A. (2007)
    3. Tumor necrosis factor alpha induction of NF-kappaB requires the novel coactivator SIMPL. (PubMed id 15485901)1 Kwon H.J....Harrington M.A. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 134728 HGNC: 17368 AceView: IRAK1BP1 Ensembl:ENSG00000146243 euGenes: HUgn134728
    ECgene: IRAK1BP1 H-InvDB: IRAK1BP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IRAK1BP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IRAK1BP1 gene:
    Search GeneIP for patents involving IRAK1BP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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