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IQUB Gene

protein-coding   GIFtS: 49
GCID: GC07M123092

IQ Motif And Ubiquitin Domain Containing

Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
IQ Motif And Ubiquitin Domain Containing1 2
IQ And Ubiquitin-Like Domain-Containing Protein2

External Ids:    HGNC: 219951   Entrez Gene: 1548652   Ensembl: ENSG000001646757   UniProtKB: Q8NA543   

Export aliases for IQUB gene to outside databases

Previous GC identifers: GC07M122880 GC07M117455


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IQUB Gene:
IQUB (IQ motif and ubiquitin domain containing) is a protein-coding gene. Diseases associated with IQUB include wiskott-aldrich syndrome, and breast and colorectal cancer.

UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54
Function: May play roles in cilia formation and/or maintenance (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IQUB gene promoter:
         SRF   HOXA3   SRF (504 AA)   FOXO3   HNF-3beta   FOXO3b   AREB6   POU2F1   POU2F1a   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): IQUB promoter sequence
   Search Chromatin IP Primers for IQUB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IQUB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.32   Ensembl cytogenetic band:  7q31.32   HGNC cytogenetic band: 7q31.32

IQUB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IQUB gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M123092:  view genomic region     (about GC identifiers)

Start:
123,092,235 bp from pter      End:
123,175,131 bp from pter
Size:
82,897 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 122,480,849-122,563,331     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54 (See protein sequence)
Recommended Name: IQ and ubiquitin-like domain-containing protein  
Size: 791 amino acids; 92581 Da
1 PDB 3D structure from and Proteopedia for IQUB:
2DAF (3D)    
Secondary accessions: A4D0X0 Q49AL6 Q4G189 Q5BJD9 Q6NUH6 Q8N9Y2
Alternative splicing: 2 isoforms:  Q8NA54-1   Q8NA54-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IQUB: NX_Q8NA54

Explore proteomics data for IQUB at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IQUB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001269784.1  NP_849149.3  

    ENSEMBL proteins: 
     ENSP00000417769   ENSP00000324882   ENSP00000417285   ENSP00000417636   ENSP00000388498  

    IQUB Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for IQUB
    OriGene Protein Over-expression Lysate for IQUB
    OriGene MassSpec for IQUB
    OriGene Custom Protein Services for IQUB
    GenScript Custom Purified and Recombinant Proteins Services for IQUB
    Novus Biologicals IQUB Protein
    Novus Biologicals IQUB Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for IQUB

    IQUB Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for IQUB
    Novus Biologicals IQUB Antibodies
    Abcam antibodies for IQUB
    Cloud-Clone Corp. Antibodies for IQUB
    ThermoFisher Antibodies for IQUB
    LSBio Antibodies in human, mouse, rat for IQUB

    IQUB Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for IQUB
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for IQUB
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for IQUB
    Cloud-Clone Corp. CLIAs for IQUB


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000626 Ubiquitin_dom

    Graphical View of Domain Structure for InterPro Entry Q8NA54

    ProtoNet protein and cluster: Q8NA54

    1 Blocks protein domain: IPB000626 Ubiquitin domain

    UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54
    Similarity: Contains 1 IQ domain
    Similarity: Contains 1 ubiquitin-like domain


    IQUB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IQUB_HUMAN, Q8NA54
    Function: May play roles in cilia formation and/or maintenance (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    IQUB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IQUB:
     Decreased p24 protein expressi 

         1 MGI phenotypic allele for Iqub (no phenotypes)

    IQUB for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IQUB
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IQUB

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IQUB
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IQUB

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat IQUB using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate IQUB:
    hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IQUB
    Predesigned siRNA for gene silencing in human, mouse, rat IQUB

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IQUB

    Clone
    Products:
         
    OriGene clones in human, mouse for IQUB (see all 7)
    OriGene ORF clones in mouse, rat for IQUB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IQUB (NM_178827)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IQUB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQUB

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for IQUB
    Browse ESI BIO Cell Lines and PureStem Progenitors for IQUB 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQUB


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    golgi apparatus1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--
    GO:0031514motile cilium IEA--

    IQUB for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IQUB
    Interactions:

        Search GeneGlobe Interaction Network for IQUB

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for IQUB (Q8NA542, 3 ENSP000003248824) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDFIQ997502, 3, ENSP000002303214MINT-66730 I2D: score=4 STRING: ENSP00000230321
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0060271cilium morphogenesis IEA--

    IQUB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IQUB



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IQUB gene (2 alternative transcripts): 
    NM_001282855.1  NM_178827.4  

    Unigene Cluster for IQUB:

    IQ motif and ubiquitin domain containing
    Hs.159650  [show with all ESTs]
    Unigene Representative Sequence: AK127736
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000466202(uc011kny.2 uc003vkn.3) ENST00000324698(uc003vko.3 uc010lkt.3)
    ENST00000484508(uc003vkp.1) ENST00000469057 ENST00000483567(uc003vkq.2)
    ENST00000488987 ENST00000434450

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IQUB using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate IQUB:
    hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IQUB
    Predesigned siRNA for gene silencing in human, mouse, rat IQUB
    Clone
    Products:
         
    OriGene clones in human, mouse for IQUB (see all 7)
    OriGene ORF clones in mouse, rat for IQUB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IQUB (NM_178827)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IQUB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQUB
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for IQUB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IQUB
      QuantiTect SYBR Green Assays in human, mouse, rat IQUB
      QuantiFast Probe-based Assays in human, mouse, rat IQUB

    Additional mRNA sequence: 

    AK093153.1 AK127736.1 BC032838.2 BC036121.1 BC057256.1 BC068607.1 BC091520.1 BC128181.1 

    6 DOTS entries:

    DT.95150617  DT.100599  DT.101967132  DT.95360684  DT.121042821  DT.91727673 

    Selected AceView cDNA sequences (see all 29):

    AA918459 BC068607 BE326812 BX110263 BC036121 BC032838 AK127736 AX747958 
    BI559932 BG771582 W24994 BC057256 AK093153 AI198669 BG772966 BF436242 
    BC026173 AW665017 AI027604 AI377787 BQ435485 AK093393 NM_178827 AX748096 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IQUB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCAGATGGA
    IQUB Expression
    About this image

    IQUB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IQUB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.159650
        Custom PCR Arrays for IQUB
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for IQUB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IQUB
    QuantiTect SYBR Green Assays in human, mouse, rat IQUB
    QuantiFast Probe-based Assays in human, mouse, rat IQUB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQUB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for IQUB gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Iqub1 , 5 IQ motif and ubiquitin domain containing1, 5 76.59(n)1
    69.99(a)1
      6 (11.28 cM)5
    2147041  NM_172535.31  NP_766123.21 
     244448655 
    chicken
    (Gallus gallus)
    Aves IQUB1 IQ motif and ubiquitin domain containing 67.01(n)
    58.22(a)
      417754  XM_004937526.1  XP_004937583.1 
    lizard
    (Anolis carolinensis)
    Reptilia IQUB6
    IQ motif and ubiquitin domain containing
    42(a)
    1 ↔ 1
    5(67509051-67556027)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162262 Xenopus laevis transcribed sequences 77.55(n)    BJ085065.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.185262 Transcribed sequence 71.51(n)    BQ419554.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG138551 CG13855 44.23(n)
    33.08(a)
      42629  NM_142780.3  NP_651037.1 


    ENSEMBL Gene Tree for IQUB (if available)
    TreeFam Gene Tree for IQUB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IQUB (see all 1509)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362914
    A colorectal cancer sample4--see VAR_0362912 R H mis40--------
    rs737202481,2
    C--123091788(+) CTGGCC/TGTTCC 1 -- ds50012Minor allele frequency- T:0.04WA 120
    rs21031831,2
    H--123091829(+) ATCTTC/TTTTAC 1 -- ds50014Minor allele frequency- T:0.00NS EA 420
    rs737202491,2
    C,F--123091958(+) CCACAC/GCTTAT 1 -- ds50012Minor allele frequency- G:0.10WA 120
    rs1483968741,2
    --123091993(+) CTCCTG/TGGCTT 1 -- ds50010--------
    rs1172544141,2
    C,F--123092120(+) AGGGCG/ATTGTT 1 -- ds50011Minor allele frequency- A:0.05NA 120
    rs1440110671,2
    --123092147(+) GTTTAC/TTCTTC 1 -- ds50010--------
    rs1858376171,2
    --123092158(+) TTATAA/GTTTCA 1 -- ds50010--------
    rs77894091,2
    C,F,H--123092302(+) GCAGAC/TGATAA 1 -- ut3120Minor allele frequency- T:0.21NS EA NA WA 2482
    rs1454017201,2
    C--123092312(+) ACTGC-/AAAG  
            
    AAAGA
    1 -- ut310--------

    HapMap Linkage Disequilibrium report for IQUB (123092235 - 123175131 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for IQUB:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2646544CNV Deletion19546169
    nsv524192CNV Gain19592680
    nsv889126CNV Gain21882294
    nsv889125CNV Gain21882294
    nsv831116CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IQUB
    DNA2.0 Custom Variant and Variant Library Synthesis for IQUB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for IQUB:    About MalaCards
    wiskott-aldrich syndrome    breast and colorectal cancer    hiv-1    colorectal cancer
    malaria


    IQUB for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Genetic Association Database (GAD): IQUB
    Human Genome Epidemiology (HuGE) Navigator: IQUB (2 documents)

    Export disorders for IQUB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IQUB gene integrated from 10 sources:
    (articles sorted by number of sources associating them with IQUB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (J. Infect. Dis. 2010)
    4. Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities. (PubMed id 20602751)1 Docherty S.J....Plomin R. (BMC Genet. 2010)
    5. Identification of host proteins required for HIV infection through a functional genomic screen. (PubMed id 18187620)1 Brass A.L....Elledge S.J. (Science 2008)
    6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    9. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (Science 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 154865 HGNC: 21995 AceView: FLJ35834 Ensembl:ENSG00000164675 euGenes: HUgn154865
    ECgene: IQUB H-InvDB: IQUB

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IQUB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IQUB gene:
    Search GeneIP for patents involving IQUB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for IQUB  
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     Block miRNA regulation of human, mouse, rat IQUB using miScript Target Protectors SeqTarget long-range PCR primers for resequencing IQUB
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IQUB Predesigned siRNA for gene silencing in human, mouse, rat IQUB
     QuantiFast Probe-based Assays in human, mouse, rat IQUB QuantiTect SYBR Green Assays in human, mouse, rat IQUB
     Custom PCR Arrays for IQUB Search Chromatin IP Primers for IQUB
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     Search Tocris compounds for IQUB
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     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for IQUB
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     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IQUB
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