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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IQUB Gene

protein-coding   GIFtS: 48
GCID: GC07M123092

IQ Motif And Ubiquitin Domain Containing

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
IQ Motif And Ubiquitin Domain Containing1 2
IQ And Ubiquitin-Like Domain-Containing Protein2

External Ids:    HGNC: 219951   Entrez Gene: 1548652   Ensembl: ENSG000001646757   UniProtKB: Q8NA543   

Export aliases for IQUB gene to outside databases

Previous GC identifers: GC07M122880 GC07M117455


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IQUB Gene: 
IQUB (IQ motif and ubiquitin domain containing) is a protein-coding gene. Diseases associated with IQUB include wiskott-aldrich syndrome.

UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54
Function: May play roles in cilia formation and/or maintenance (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IQUB gene promoter:
         SRF   HOXA3   SRF (504 AA)   FOXO3   HNF-3beta   FOXO3b   AREB6   POU2F1   POU2F1a   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): IQUB promoter sequence
   Search SABiosciences Chromatin IP Primers for IQUB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQUB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.32   Ensembl cytogenetic band:  7q31.32   HGNC cytogenetic band: 7q31.32

IQUB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IQUB gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M123092:  view genomic region     (about GC identifiers)

Start:
123,092,235 bp from pter      End:
123,175,131 bp from pter
Size:
82,897 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 122,480,849-122,563,331     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54 (See protein sequence)
Recommended Name: IQ and ubiquitin-like domain-containing protein  
Size: 791 amino acids; 92581 Da
1 PDB 3D structure from and Proteopedia for IQUB:
2DAF (3D)    
Secondary accessions: A4D0X0 Q49AL6 Q4G189 Q5BJD9 Q6NUH6 Q8N9Y2
Alternative splicing: 2 isoforms:  Q8NA54-1   Q8NA54-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IQUB: NX_Q8NA54

Explore proteomics data for IQUB at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NA54

  • IQUB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IQUB Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001269784.1  NP_849149.3  

    ENSEMBL proteins: 
     ENSP00000417769   ENSP00000324882   ENSP00000417285   ENSP00000417636   ENSP00000388498  

    Human Recombinant Protein Products for IQUB: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for IQUB
    OriGene Protein Over-expression Lysate for IQUB
    OriGene MassSpec for IQUB 
    OriGene Custom Protein Services for IQUB
    GenScript Custom Purified and Recombinant Proteins Services for IQUB
    Novus Biologicals IQUB Protein
    Novus Biologicals IQUB Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for IQUB 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--
    GO:0031514motile cilium IEA--

    IQUB for ontologies           About GeneDecksing



    IQUB Antibody Products: 
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    Abcam antibodies for IQUB
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    LSBio Antibodies in human, mouse, rat for IQUB 

    Assay Products for IQUB: 
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    Cloud-Clone Corp. ELISAs for IQUB 
    Cloud-Clone Corp. CLIAs for IQUB


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000626 Ubiquitin
     IPR019955 Ubiquitin_supergroup

    Graphical View of Domain Structure for InterPro Entry Q8NA54

    ProtoNet protein and cluster: Q8NA54

    1 Blocks protein domain: IPB000626 Ubiquitin domain

    UniProtKB/Swiss-Prot: IQUB_HUMAN, Q8NA54
    Similarity: Contains 1 IQ domain
    Similarity: Contains 1 ubiquitin-like domain


    IQUB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IQUB_HUMAN, Q8NA54
    Function: May play roles in cilia formation and/or maintenance (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    IQUB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IQUB:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for IQUB 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IQUB

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IQUB 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IQUB 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IQUB
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IQUB:
    hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IQUB
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IQUB

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IQUB
    Sirion Biotech Customized adenovirus for overexpression of IQUB

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for IQUB (see all 7)
    OriGene ORF clones in mouse, rat for IQUB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IQUB (NM_178827)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IQUB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQUB
    Sirion Biotech Customized lentivirus for stable overexpression of IQUB 
                         Customized lentivirus expression plasmids for stable overexpression of IQUB 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for IQUB
    Search LifeMap BioReagents cell lines for IQUB
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQUB


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IQUB

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for IQUB (Q8NA542, 3 ENSP000003248824) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDFIQ997502, 3, ENSP000002303214MINT-66730 I2D: score=4 STRING: ENSP00000230321
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0060271cilium morphogenesis IEA--

    IQUB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IQUB

    Search CenterWatch for drugs/clinical trials and news about IQUB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IQUB gene (2 alternative transcripts): 
    NM_001282855.1  NM_178827.4  

    Unigene Cluster for IQUB:

    IQ motif and ubiquitin domain containing
    Hs.159650  [show with all ESTs]
    Unigene Representative Sequence: AK127736
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000466202(uc011kny.2 uc003vkn.3) ENST00000324698(uc003vko.3 uc010lkt.3)
    ENST00000484508(uc003vkp.1) ENST00000469057 ENST00000483567(uc003vkq.2)
    ENST00000488987 ENST00000434450
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IQUB
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IQUB:
    hsa-miR-4282
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IQUB
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IQUB
    Clone
    Products:
         
    OriGene clones in human, mouse for IQUB (see all 7)
    OriGene ORF clones in mouse, rat for IQUB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IQUB (NM_178827)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IQUB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQUB
    Sirion Biotech Customized lentivirus for stable overexpression of IQUB 
                         Customized lentivirus expression plasmids for stable overexpression of IQUB 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for IQUB
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IQUB
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQUB
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQUB

    Additional mRNA sequence: 

    AK093153.1 AK127736.1 BC032838.2 BC036121.1 BC057256.1 BC068607.1 BC091520.1 BC128181.1 

    6 DOTS entries:

    DT.95150617  DT.100599  DT.101967132  DT.95360684  DT.121042821  DT.91727673 

    24/29 AceView cDNA sequences (see all 29):

    BC068607 AA918459 BE326812 BX110263 BC032838 BC036121 AK127736 AK093153 
    AW665017 AX747958 BQ435485 AX748096 BC026173 AK093393 W24994 AI027604 
    BF436242 AI198669 BC057256 NM_178827 BI559932 BG771582 AI377787 BG772966 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IQUB expression in normal human tissues (normalized intensities)      IQUB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCAGATGGA
    IQUB Expression
    About this image


    IQUB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Testis (Reproductive System)

    See IQUB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IQUB

    SOURCE GeneReport for Unigene cluster: Hs.159650
        SABiosciences Custom PCR Arrays for IQUB
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for IQUB
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IQUB
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQUB
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQUB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQUB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for IQUB gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Iqub1 , 5 IQ motif and ubiquitin domain containing1, 5 76.59(n)1
    69.99(a)1
      6 (11.28 cM)5
    2147041  NM_172535.31  NP_766123.21 
     244448655 
    chicken
    (Gallus gallus)
    Aves IQUB1 IQ motif and ubiquitin domain containing 67.07(n)
    58.42(a)
      417754  XM_415998.3  XP_415998.2 
    lizard
    (Anolis carolinensis)
    Reptilia IQUB6
    Uncharacterized protein
    42(a)
    1 ↔ 1
    5(67509051-67556027)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162262 Xenopus laevis transcribed sequences 77.55(n)    BJ085065.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.185262 Transcribed sequence 71.51(n)    BQ419554.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG138551 CG13855 43.86(n)
    32.75(a)
      42629  NM_142780.2  NP_651037.1 


    ENSEMBL Gene Tree for IQUB (if available)
    TreeFam Gene Tree for IQUB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1509 SNPs in IQUB are shown (see all 1509)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362914
    A colorectal cancer sample4--see VAR_0362912 R H mis40--------
    rs737202481,2
    C--123091788(+) CTGGCC/TGTTCC 1 -- ds50012Minor allele frequency- T:0.04WA 120
    rs21031831,2
    H--123091829(+) ATCTTC/TTTTAC 1 -- ds50014Minor allele frequency- T:0.00NS EA 420
    rs737202491,2
    C,F--123091958(+) CCACAC/GCTTAT 1 -- ds50012Minor allele frequency- G:0.10WA 120
    rs1483968741,2
    --123091993(+) CTCCTG/TGGCTT 1 -- ds50010--------
    rs1172544141,2
    C,F--123092120(+) AGGGCG/ATTGTT 1 -- ds50011Minor allele frequency- A:0.05NA 120
    rs1440110671,2
    --123092147(+) GTTTAC/TTCTTC 1 -- ds50010--------
    rs1858376171,2
    --123092158(+) TTATAA/GTTTCA 1 -- ds50010--------
    rs77894091,2
    C,F,H--123092302(+) GCAGAC/TGATAA 1 -- ut3120Minor allele frequency- T:0.21NS EA NA WA 2482
    rs1454017201,2
    C--123092312(+) ACTGC-/AAAG  
            
    AAAGA
    1 -- ut310--------

    HapMap Linkage Disequilibrium report for IQUB (123092235 - 123175131 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for IQUB:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2646544CNV Deletion19546169
    nsv524192CNV Gain19592680
    nsv889126CNV Gain21882294
    nsv889125CNV Gain21882294
    nsv831116CNV Gain+Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing IQUB
    DNA2.0 Custom Variant and Variant Library Synthesis for IQUB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for IQUB:    About MalaCards
    wiskott-aldrich syndrome    


    IQUB for disorders           About GeneDecksing

    Genetic Association Database (GAD): IQUB
    Human Genome Epidemiology (HuGE) Navigator: IQUB (2 documents)

    Export disorders for IQUB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IQUB gene integrated from 9 sources:
    (articles sorted by number of sources associating them with IQUB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Genetic associations of variants in genes encoding HI V-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (2010)
    4. Generalist genes analysis of DNA markers associated w ith mathematical ability and disability reveals shared influence across ages an d abilities. (PubMed id 20602751)1 Docherty S.J....Plomin R. (2010)
    5. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    8. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 154865 HGNC: 21995 AceView: FLJ35834 Ensembl:ENSG00000164675 euGenes: HUgn154865
    ECgene: IQUB H-InvDB: IQUB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IQUB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IQUB gene:
    Search GeneIP for patents involving IQUB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IQUB
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     Search for Antibodies & Assays

     Regulatory tfbs in IQUB promoter
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     Proteins for IQUB
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQUB
     inGenious Targeting Laboratory - Custom generated mouse model solutions for IQUB
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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