External Ids for IQGAP2 Gene
Previous GeneCards Identifiers for IQGAP2 Gene
This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
GeneCards Summary for IQGAP2 Gene
IQGAP2 (IQ Motif Containing GTPase Activating Protein 2) is a Protein Coding gene. Among its related pathways are Signaling by Rho GTPases and Actin Nucleation by ARP-WASP Complex. GO annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is IQGAP3.
UniProtKB/Swiss-Prot for IQGAP2 Gene
Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.