External Ids for IQGAP2 Gene
Previous GeneCards Identifiers for IQGAP2 Gene
This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
GeneCards Summary for IQGAP2 Gene
IQGAP2 (IQ Motif Containing GTPase Activating Protein 2) is a Protein Coding gene. Among its related pathways are Regulation of actin cytoskeleton and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include actin binding. An important paralog of this gene is IQGAP3.
UniProtKB/Swiss-Prot for IQGAP2 Gene
Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin