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Aliases for IQCJ Gene

Aliases for IQCJ Gene

  • IQ Motif Containing J 2 3 5

External Ids for IQCJ Gene

Previous GeneCards Identifiers for IQCJ Gene

  • GC03U900617
  • GC03P160269
  • GC03P158680
  • GC03P156182

Summaries for IQCJ Gene

GeneCards Summary for IQCJ Gene

IQCJ (IQ Motif Containing J) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCJ Gene

Genomics for IQCJ Gene

Regulatory Elements for IQCJ Gene

Enhancers for IQCJ Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F158991 0.2 ENCODE 11.7 +28.4 28429 0.2 ZFP69B KLF1 ZNF692 GLIS1 KLF7 IQCJ IQCJ-SCHIP1
GH03F158917 0.4 ENCODE 11.4 -44.8 -44827 1.0 CTCF ZNF654 PKNOX1 SMC3 ZIC2 RAD21 IQCJ GFM1 RSRC1 GC03M158916
GH03F159465 0.3 FANTOM5 2.2 +502.7 502739 0.1 SCHIP1 IQCJ RPS2P19 LOC100420738
GH03F158961 0.6 ENCODE 0.8 -1.1 -1091 1.0 HDAC1 ATF1 CBX3 TBL1XR1 ARNT CHAMP1 GATA2 FOS MIER1 ZBTB2 IQCJ GC03M158916
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around IQCJ on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCJ Gene

Chromosome:
3
Start:
158,962,928 bp from pter
End:
159,266,307 bp from pter
Size:
303,380 bases
Orientation:
Plus strand

Genomic View for IQCJ Gene

Genes around IQCJ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCJ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCJ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCJ Gene

Proteins for IQCJ Gene

  • Protein details for IQCJ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q1A5X6-IQCJ_HUMAN
    Recommended name:
    IQ domain-containing protein J
    Protein Accession:
    Q1A5X6
    Secondary Accessions:
    • B7ZMM2
    • B9EH97
    • Q1A5X5

    Protein attributes for IQCJ Gene

    Size:
    159 amino acids
    Molecular mass:
    18226 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IQCJ Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IQCJ Gene

Post-translational modifications for IQCJ Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCJ Gene

No data available for DME Specific Peptides for IQCJ Gene

Domains & Families for IQCJ Gene

Protein Domains for IQCJ Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCJ Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q1A5X6

UniProtKB/Swiss-Prot:

IQCJ_HUMAN :
  • Contains 1 IQ domain.
Domain:
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCJ: view

No data available for Gene Families for IQCJ Gene

Function for IQCJ Gene

Phenotypes for IQCJ Gene

genes like me logo Genes that share phenotypes with IQCJ: view

Animal Model Products

miRNA for IQCJ Gene

miRTarBase miRNAs that target IQCJ

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IQCJ Gene

Localization for IQCJ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IQCJ Gene

Pathways & Interactions for IQCJ Gene

SuperPathways for IQCJ Gene

No Data Available

Interacting Proteins for IQCJ Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000402153%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000402153 for IQCJ Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for IQCJ Gene

None

No data available for Pathways by source and SIGNOR curated interactions for IQCJ Gene

Transcripts for IQCJ Gene

mRNA/cDNA for IQCJ Gene

(3) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCJ Gene

IQ motif containing J:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCJ Gene

No ASD Table

Relevant External Links for IQCJ Gene

GeneLoc Exon Structure for
IQCJ
ECgene alternative splicing isoforms for
IQCJ

Expression for IQCJ Gene

mRNA expression in normal human tissues for IQCJ Gene

mRNA differential expression in normal tissues according to GTEx for IQCJ Gene

This gene is overexpressed in Testis (x10.8), Pituitary (x4.8), and Brain - Amygdala (x4.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCJ Gene



Protein tissue co-expression partners for IQCJ Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of IQCJ Gene:

IQCJ

SOURCE GeneReport for Unigene cluster for IQCJ Gene:

Hs.570685
genes like me logo Genes that share expression patterns with IQCJ: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for IQCJ Gene

Orthologs for IQCJ Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCJ Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IQCJ 34 35
  • 99.58 (n)
mouse
(Mus musculus)
Mammalia Iqcj 34 16 35
  • 88.55 (n)
cow
(Bos Taurus)
Mammalia IQCJ 35
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCJ 35
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IQCJ 35
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IQCJ 35
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves IQCJ 35
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IQCJ 35
  • 66 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii IQCJ 35
  • 45 (a)
OneToOne
Species where no ortholog for IQCJ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCJ Gene

ENSEMBL:
Gene Tree for IQCJ (if available)
TreeFam:
Gene Tree for IQCJ (if available)

Paralogs for IQCJ Gene

(1) SIMAP similar genes for IQCJ Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with IQCJ: view

No data available for Paralogs for IQCJ Gene

Variants for IQCJ Gene

Sequence variations from dbSNP and Humsavar for IQCJ Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1020470 -- 159,252,925(-) ATAAT(A/G)TGCAG intron-variant
rs1039399 -- 159,140,815(+) CCAAA(A/C)TAGGC intron-variant
rs10433351 -- 159,095,844(+) cttta(G/T)agcag intron-variant
rs10433457 -- 159,114,064(+) AAATT(A/G)GCCAG intron-variant
rs10446284 -- 159,095,904(+) caaat(G/T)gtatt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCJ Gene

Variant ID Type Subtype PubMed ID
esv23950 CNV loss 19812545
esv24169 CNV loss 19812545
esv2421756 CNV deletion 20811451
esv2516721 CNV insertion 19546169
esv2656480 CNV deletion 23128226
esv2726104 CNV deletion 23290073
esv2762352 CNV gain 21179565
esv3562788 CNV deletion 23714750
esv3598351 CNV loss 21293372
esv3598352 CNV loss 21293372
esv3598354 CNV loss 21293372
esv3598355 CNV gain 21293372
esv3598356 CNV loss 21293372
esv3598357 CNV loss 21293372
esv3598360 CNV loss 21293372
esv3893792 CNV loss 25118596
esv5527 OTHER inversion 19470904
nsv1004124 CNV gain 25217958
nsv1010336 CNV loss 25217958
nsv1010828 CNV gain 25217958
nsv437890 CNV loss 16468122
nsv470971 CNV gain 18288195
nsv592125 CNV loss 21841781
nsv998949 CNV gain 25217958

Variation tolerance for IQCJ Gene

Residual Variation Intolerance Score: 67.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.01; 0.23% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCJ Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IQCJ

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCJ Gene

Disorders for IQCJ Gene

Relevant External Links for IQCJ

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IQCJ

No disorders were found for IQCJ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCJ Gene

Publications for IQCJ Gene

  1. IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein. (PMID: 17045569) Kwasnicka-Crawford D.A. … Scherer S.W. (Biochem. Biophys. Res. Commun. 2006) 2 3 4 64
  2. Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments. (PMID: 18550753) Martin P.M. … Goutebroze L. (J. Neurosci. 2008) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for IQCJ Gene

Sources for IQCJ Gene

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