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Aliases for IQCH Gene

Aliases for IQCH Gene

  • IQ Motif Containing H 2 3
  • Testis Development Protein NYD-SP5 3 4
  • NYDSP5 3 6
  • IQ Domain-Containing Protein H 3

External Ids for IQCH Gene

Previous GeneCards Identifiers for IQCH Gene

  • GC15P065335
  • GC15P067547
  • GC15P044381

Summaries for IQCH Gene

GeneCards Summary for IQCH Gene

IQCH (IQ Motif Containing H) is a Protein Coding gene.

UniProtKB/Swiss-Prot for IQCH Gene

  • May play a regulatory role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCH Gene

Genomics for IQCH Gene

Regulatory Elements for IQCH Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IQCH Gene

67,254,800 bp from pter
67,502,260 bp from pter
247,461 bases
Plus strand

Genomic View for IQCH Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCH Gene

Proteins for IQCH Gene

  • Protein details for IQCH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein H
    Protein Accession:
    Secondary Accessions:
    • A8K8W3
    • C9JPR6
    • D6RJ88
    • Q4G0S6
    • Q8NEH9
    • Q9BWX2
    • Q9H9Y1
    • Q9UF88

    Protein attributes for IQCH Gene

    1027 amino acids
    Molecular mass:
    117349 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IQCH Gene


neXtProt entry for IQCH Gene

Proteomics data for IQCH Gene at MOPED

Post-translational modifications for IQCH Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for IQCH Gene

Domains for IQCH Gene

Protein Domains for IQCH Gene


Suggested Antigen Peptide Sequences for IQCH Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCH: view

No data available for Gene Families for IQCH Gene

Function for IQCH Gene

Molecular function for IQCH Gene

UniProtKB/Swiss-Prot Function:
May play a regulatory role in spermatogenesis.

Gene Ontology (GO) - Molecular Function for IQCH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IQCH: view

Phenotypes for IQCH Gene

GenomeRNAi human phenotypes for IQCH:
genes like me logo Genes that share phenotypes with IQCH: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCH Gene

Localization for IQCH Gene

Subcellular locations from

Jensen Localization Image for IQCH Gene COMPARTMENTS Subcellular localization image for IQCH gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCH Gene

Pathways for IQCH Gene

SuperPathways for IQCH Gene

No Data Available

Interacting Proteins for IQCH Gene

Selected Interacting proteins: Q86VS3-IQCH_HUMAN for IQCH Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for IQCH Gene


No data available for Pathways by source for IQCH Gene

Transcripts for IQCH Gene

Unigene Clusters for IQCH Gene

IQ motif containing H:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCH

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCH Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ·
SP1: - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - - -
SP5: -

ExUns: 22c ^ 23
SP5: -

Relevant External Links for IQCH Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCH Gene

mRNA expression in normal human tissues for IQCH Gene

mRNA differential expression in normal tissues according to GTEx for IQCH Gene

This gene is overexpressed in Testis (10.6).

Protein differential expression in normal tissues for IQCH Gene

This gene is overexpressed in Plasma (63.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for IQCH Gene

SOURCE GeneReport for Unigene cluster for IQCH Gene Hs.657894

mRNA Expression by UniProt/SwissProt for IQCH Gene

Tissue specificity: Expressed in fetal and adult testis, in germ cells but not somatic cells.
genes like me logo Genes that share expressions with IQCH: view

Expression partners for IQCH Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for IQCH Gene

Orthologs for IQCH Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCH Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IQCH 35
  • 85.9 (n)
  • 79.22 (a)
  • 76 (a)
(Canis familiaris)
Mammalia IQCH 35
  • 88.09 (n)
  • 81.79 (a)
  • 81 (a)
(Mus musculus)
Mammalia Iqch 35
  • 80.75 (n)
  • 74.7 (a)
Iqch 16
Iqch 36
  • 70 (a)
(Pan troglodytes)
Mammalia IQCH 35
  • 99.48 (n)
  • 99.03 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Iqch 35
  • 79.4 (n)
  • 71.56 (a)
(Monodelphis domestica)
Mammalia IQCH 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia IQCH 36
  • 42 (a)
(Gallus gallus)
Aves LOC415554 35
  • 66.56 (n)
  • 57.33 (a)
  • 54 (a)
(Anolis carolinensis)
Reptilia IQCH 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia iqch 35
  • 58.2 (n)
  • 52.17 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.13986 35
(Danio rerio)
Actinopterygii iqch 35
  • 54.18 (n)
  • 44.93 (a)
iqch 36
  • 39 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13356 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 47 (a)
Species with no ortholog for IQCH:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCH Gene

Gene Tree for IQCH (if available)
Gene Tree for IQCH (if available)

Paralogs for IQCH Gene

No data available for Paralogs for IQCH Gene

Variants for IQCH Gene

Sequence variations from dbSNP and Humsavar for IQCH Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs869304 -- 67,357,640(+) GTTGC(A/G)TCATT intron-variant
rs869305 -- 67,357,757(+) AGGTT(C/G)TACTG intron-variant
rs870528 -- 67,313,906(+) TAAAG(C/T)AATAG intron-variant
rs920913 -- 67,320,293(-) ACAGA(C/G)CAGTG intron-variant
rs956129 -- 67,336,837(-) TATTG(C/T)TCATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCH Gene

Variant ID Type Subtype PubMed ID
nsv827371 CNV Loss 20364138
esv2666605 CNV Deletion 23128226
nsv827372 CNV Loss 20364138
esv271637 CNV Insertion 20981092
esv268324 CNV Insertion 20981092
esv2663197 CNV Deletion 23128226
esv2660716 CNV Deletion 23128226

Relevant External Links for IQCH Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCH Gene

Disorders for IQCH Gene

Relevant External Links for IQCH

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for IQCH Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for IQCH Gene

Publications for IQCH Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Identification of a novel testis-specific gene and its potential roles in testis development/spermatogenesis. (PMID: 15897968) Yin L.L. … Sha J.H. (Asian J. Androl. 2005) 3 4
  5. Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians. (PMID: 18491143) Kimura T. … Inoko H. (Hum. Genet. 2008) 3 48

Products for IQCH Gene

Sources for IQCH Gene

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