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Aliases for IQCG Gene

Aliases for IQCG Gene

  • IQ Motif Containing G 2 3
  • Dynein Regulatory Complex Subunit 9 2 3
  • IQ Domain-Containing Protein G 3
  • CFAP122 3
  • DRC9 3

External Ids for IQCG Gene

Summaries for IQCG Gene

GeneCards Summary for IQCG Gene

IQCG (IQ Motif Containing G) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCG Gene

Genomics for IQCG Gene

Genomic Location for IQCG Gene

Start:
197,889,075 bp from pter
End:
197,960,142 bp from pter
Size:
71,068 bases
Orientation:
Minus strand

Genomic View for IQCG Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCG Gene

Regulatory Elements for IQCG Gene

Proteins for IQCG Gene

  • Protein details for IQCG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H095-IQCG_HUMAN
    Recommended name:
    IQ domain-containing protein G
    Protein Accession:
    Q9H095
    Secondary Accessions:
    • Q9BST2
    • Q9HAG8

    Protein attributes for IQCG Gene

    Size:
    443 amino acids
    Molecular mass:
    51918 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for IQCG Gene

    Alternative splice isoforms for IQCG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IQCG Gene

Proteomics data for IQCG Gene at MOPED

Post-translational modifications for IQCG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCG Gene

No data available for DME Specific Peptides for IQCG Gene

Domains for IQCG Gene

Protein Domains for IQCG Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

IQCG_HUMAN
Domain:
  • Contains 1 IQ domain.:
    • Q9H095
genes like me logo Genes that share domains with IQCG: view

No data available for Gene Families for IQCG Gene

Function for IQCG Gene

Gene Ontology (GO) - Molecular Function for IQCG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IQCG: view

miRNA for IQCG Gene

miRTarBase miRNAs that target IQCG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for IQCG Gene

Localization for IQCG Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IQCG Gene COMPARTMENTS Subcellular localization image for IQCG gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for IQCG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with IQCG: view

Pathways for IQCG Gene

SuperPathways for IQCG Gene

No Data Available

Interacting Proteins for IQCG Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000265239%0d%0a9606.ENSP00000272298%0d%0a
Selected Interacting proteins: Q9H095-IQCG_HUMAN ENSP00000265239 for IQCG Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for IQCG Gene

None

No data available for Pathways by source for IQCG Gene

Transcripts for IQCG Gene

Unigene Clusters for IQCG Gene

IQ motif containing G:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IQCG Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b ·
SP1: - - - - - - -
SP2: - - -
SP3: -
SP4: - -
SP5: - - - - - - - -
SP6: - - -
SP7: - -
SP8: - - - - - - -
SP9:
SP10:

ExUns: 15c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for IQCG Gene

GeneLoc Exon Structure for
IQCG
ECgene alternative splicing isoforms for
IQCG

Expression for IQCG Gene

mRNA expression in normal human tissues for IQCG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IQCG Gene

This gene is overexpressed in Testis (5.5) and Ovary (5.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for IQCG Gene

SOURCE GeneReport for Unigene cluster for IQCG Gene Hs.591675

genes like me logo Genes that share expressions with IQCG: view

Orthologs for IQCG Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IQCG 36
  • 99.02 (n)
  • 98.65 (a)
IQCG 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia IQCG 36
  • 83.22 (n)
  • 74.71 (a)
IQCG 37
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCG 36
  • 81.71 (n)
  • 72.44 (a)
IQCG 37
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Iqcg 36
  • 76.36 (n)
  • 67.67 (a)
Iqcg 16
Iqcg 37
  • 67 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IQCG 37
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IQCG 37
  • 52 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Iqcg 36
  • 75.46 (n)
  • 65.08 (a)
chicken
(Gallus gallus)
Aves IQCG 36
  • 55.08 (n)
  • 41.67 (a)
IQCG 37
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IQCG 37
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia iqcg 36
  • 57.75 (n)
  • 49.3 (a)
zebrafish
(Danio rerio)
Actinopterygii IQCG 37
  • 38 (a)
OneToOne
si:ch211-222m18.3 36
  • 52.58 (n)
  • 39.43 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 40 (a)
OneToOne
Species with no ortholog for IQCG:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCG Gene

ENSEMBL:
Gene Tree for IQCG (if available)
TreeFam:
Gene Tree for IQCG (if available)

Paralogs for IQCG Gene

No data available for Paralogs for IQCG Gene

Variants for IQCG Gene

Sequence variations from dbSNP and Humsavar for IQCG Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1129747 -- 197,956,541(+) ATTGC(A/C)CTTTA intron-variant
rs1157464 -- 197,939,485(+) CGCAG(A/G)AACGG intron-variant, upstream-variant-2KB
rs1987215 -- 197,902,853(-) ttttg(G/T)ggttc intron-variant
rs3749254 -- 197,912,956(+) CGAGA(C/G)GAGCA intron-variant
rs3749255 -- 197,944,156(-) ACGAC(A/G)ATGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for IQCG Gene

Variant ID Type Subtype PubMed ID
nsv829832 CNV Loss 17160897
esv2751989 CNV Gain 17911159
nsv878208 CNV Gain 21882294
nsv878211 CNV Gain 21882294
nsv527527 CNV Gain 19592680
nsv878212 CNV Gain 21882294
esv2660910 CNV Deletion 23128226
dgv5379n71 CNV Gain 21882294
esv1943012 CNV Deletion 18987734
esv2408312 CNV Deletion 18987734
esv2670685 CNV Deletion 23128226
nsv238027 CNV Loss 16902084
nsv483023 CNV Gain 15286789
esv2671250 CNV Deletion 23128226
nsv878215 CNV Loss 21882294
nsv878216 CNV Gain 21882294

Relevant External Links for IQCG Gene

HapMap Linkage Disequilibrium report
IQCG

Disorders for IQCG Gene

No disorders were found for IQCG Gene.

No data available for UniProtKB/Swiss-Prot for IQCG Gene

Publications for IQCG Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. (PMID: 23427265) Bower R. … Porter M.E. (Mol. Biol. Cell 2013) 2 3
  3. IQ motif-containing G (Iqcg) is required for mouse spermiogenesis. (PMID: 24362311) Harris T.P. … Schimenti J.C. (G3 (Bethesda) 2014) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for IQCG Gene

Sources for IQCG Gene

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