IQCG Gene
protein-coding GIFtS : 45
GCID: GC03 M197615
IQ motif containing G
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Aliasesfor IQCG gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases IQ Motif Containing G 1 2 DKFZp434B2271 IQ Domain-Containing Protein G2
Export aliases for IQCG gene to outside databases Previous GC identifers: GC03M199105 GC03M194918
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Summariesfor IQCG gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor IQCG gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NC_018914.1 NT_029928.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the IQCG gene promoter: AREB6 AhR MEF-2A aMEF-2 Arnt Other transcription factors Search SABiosciences Chromatin IP Primers for IQCG Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat IQCG
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3q29 Ensembl cytogenetic band: 3q29 HGNC cytogenetic band: 3q29 IQCG Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03M197615: view genomic region
(about GC identifiers )
Start:
197,615,946 bp from pter
End:
197,687,013 bp from pter
Size:
71,068 bases
Orientation:
minus strand
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Proteinsfor IQCG gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: IQCG_HUMAN, Q9H095 (See
protein sequence )Recommended Name: IQ domain-containing protein G Size : 443 amino acids; 51918 Da
Secondary accessions : Q9BST2 Q9HAG8Alternative splicing : 2 isoforms : Q9H095-1 Q9H095-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IQCG: NX_Q9H095 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9H095 IQCG Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001127907.1 NP_115639.1 ENSEMBL proteins: ENSP00000265239 ENSP00000407736 ENSP00000389897 ENSP00000406411 ENSP00000393743 Human Recombinant Protein Products: IQCG Antibody Products: Assay Products for IQCG:
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Protein
Domains / Familiesfor IQCG gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
IQCG for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q9H095 ProtoNet protein and cluster: Q9H095
UniProtKB/Swiss-Prot: IQCG_HUMAN, Q9H095 Similarity : Contains 1 IQ domain
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Functionfor IQCG gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): IQCG (NM_032263 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCG Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat IQCG
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCG
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Pathways & Interactionsfor IQCG gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IQCG 2 Interacting proteins for IQCG (Q9H095 2 , 3 ) via UniProtKB, MINT, STRING, and/or I2D About this table
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Drugs & Compoundsfor IQCG gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for IQCG Search CenterWatch for drugs/clinical trials and news about IQCG
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Transcriptsfor IQCG gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
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Primers from
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SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for IQCG gene (2 alternative transcripts): NM_001134435.2 NM_032263.3 Unigene Cluster for IQCG:
IQ motif containing G Hs.591675 [show with all ESTs ] Unigene Representative Sequence: AK095094 13 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000265239 (uc003fyp.3 ) ENST00000455191 (uc003fyo.3 ) ENST00000490748 (uc003fyn.3 )ENST00000478903 ENST00000485787 ENST00000469822 ENST00000473225 ENST00000453254 (uc003fyq.4 )ENST00000416896 ENST00000480302 ENST00000463651 ENST00000452735 ENST00000493624 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): IQCG (NM_032263 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCG Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat IQCG
Additional cDNA sequence: AK021729.1 AK027224.1 AK095094.1 AK096574.1 AL136889.1 BC004816.1 BC016156.1 BC068973.1 BC136253.1 CR533515.1
12 DOTS entries : DT.309217 DT.87017877
DT.97802270 DT.91750441 DT.95196576 DT.101979640 DT.95370440 DT.91750440 DT.100811240 DT.100741891 DT.95370439 DT.120919030 24/123 AceView cDNA sequences (see all 123 ):
AV708221 AL136889 NM_032263 AI859303 BG211682 AL041282 AI190567 BX439227 CR611369 BQ267461 AI564338 AI564330 AU117778 W74751 AW450885 CR533515 BM718323 AA043561 BC068973 AW880394 BE256850 BM908080 AK021729 AI914033 GeneLoc Exon Structure 5/10 Alternative Splicing Database (ASD) splice patterns (SP) for IQCG (see all 10 ) About this scheme ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · SP1 :           -   -   -   -       -   -               -               SP2 :                       -   -               -               SP3 :                                       -               SP4 :                       -   -                             SP5 :   -   -       -   -   -   -       -   -                            
ExUns: 15c SP1 :   SP2 :   SP3 :   SP4 :   SP5 :  
ECgene alternative splicing isoforms for IQCG
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Expression for IQCG gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IQCG expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAAACCAATA
About this image IQCG expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See IQCG Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IQCG SOURCE GeneReport for Unigene cluster: Hs.591675 SABiosciences Custom PCR Arrays for IQCG Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for IQCGBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat IQCG QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat IQCG QIAGEN QuantiFast Probe-based Assays in human , mouse , rat IQCG In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCG
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Orthologsfor IQCG gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for IQCG gene from 3/18 species (see all 18 ) About this table
ENSEMBL Gene Tree for IQCG (if available)TreeFam Gene Tree for IQCG (if available)
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Paralogsfor IQCG gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IQCG gene IQCD 2
IQCG for paralogs About GeneDecksing
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Genomic Variantsfor IQCG gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 3 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for IQCG (197615946 - 197687013 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for IQCG 3 CNVs : 6232 0044 8440 2 Indels : 46385 46384
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing IQCG
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Disorders
/ Diseasesfor IQCG gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
IQCG for disorders About MalaCards
IQCG for disorders About GeneDecksing
OMIM gene information: 612477
OMIM disorders : --Export disorders for IQCG gene to outside databases
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Publicationsfor IQCG gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for IQCG gene integrated from 9 sources : (articles sorted by number of sources associating them with IQCG) Utopia : connect your pdf to the dynamic world of online information
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166) 1 , 2 , 3 Wiemann S.... Poustka A. (2001) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206) 1 Vinayagam A....Wanker E.E. (2011) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 1 Stelzl U.... Wanker E.E. (2005) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for IQCG gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing IQCG gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing IQCG gene
(According to HUGE )
About This Section --
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Specialized Databases showing IQCG gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for IQCG Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for IQCG gene: Search GeneIP for patents involving IQCG GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IQCG gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for IQCG OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for IQCG OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for IQCG Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for IQCG OriGene 3'-UTR Clone for IQCG OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for IQCG Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for IQCG OriGene Custom Protein Services for IQCG OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IQCG QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing IQCG QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat IQCG QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat IQCG QIAGEN QuantiFast Probe-based Assays in human , mouse , rat IQCG QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat IQCG
Search Tocris compounds for IQCG
IQCG Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCG
ThermoFisher Antibodies for IQCG
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat IQCG
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Orthologs for IQCG
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Summaries for IQCG
Transcripts for IQCG
Variants for IQCG
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