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Aliases for IQCF6 Gene

Aliases for IQCF6 Gene

  • IQ Motif Containing F6 2 3 5

External Ids for IQCF6 Gene

Summaries for IQCF6 Gene

GeneCards Summary for IQCF6 Gene

IQCF6 (IQ Motif Containing F6) is a Protein Coding gene. An important paralog of this gene is IQCF5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF6 Gene

Genomics for IQCF6 Gene

Regulatory Elements for IQCF6 Gene

Enhancers for IQCF6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F052243 1.5 FANTOM5 ENCODE 13.9 -466.1 -466113 4.9 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 FOS SP3 PBRM1 PPM1M LOC101929054 GLYCTK IQCF2 IQCF5 PHF7 IQCF6 IQCF1 WDR82
GH03F051678 1.4 FANTOM5 Ensembl ENCODE 12.7 +98.8 98810 4.1 HDGF ELF3 TBP PKNOX1 SIN3A ARID4B RAD21 GATA2 EGR1 ELK1 IQCF6 DCAF1 RNU6ATAC29P GPR62 IQCF1 IQCF5 IQCF2 RNA5SP132 PIR41340
GH03F052074 0.6 FANTOM5 28.7 -294.8 -294818 0.2 CTCF NCOR1 ZMYM3 REST NR2F2 IQCF2 PHF7 IQCF5 IQCF1 IQCF6 LINC00696 POC1A
GH03F051684 1.5 FANTOM5 Ensembl ENCODE 10.2 +93.5 93543 3.6 ELF3 ARID4B RAD21 ZNF48 EGR1 SCRT2 ZNF143 EGR2 ZNF654 MIER2 TEX264 DCAF1 RNU6ATAC29P IQCF6 RPL29 RNA5SP132 PIR41340
GH03F051800 0.6 ENCODE 11.6 -20.4 -20366 0.1 CTCF ZNF654 ZNF143 SMC3 TRIM22 RAD21 IQCF6 IQCF5 GC03P051793 IQCF4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IQCF6 on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCF6 Gene

Chromosome:
3
Start:
51,778,561 bp from pter
End:
51,779,773 bp from pter
Size:
1,213 bases
Orientation:
Minus strand

Genomic View for IQCF6 Gene

Genes around IQCF6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCF6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCF6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF6 Gene

Proteins for IQCF6 Gene

  • Protein details for IQCF6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MYZ5-IQCF6_HUMAN
    Recommended name:
    IQ domain-containing protein F6
    Protein Accession:
    A8MYZ5

    Protein attributes for IQCF6 Gene

    Size:
    107 amino acids
    Molecular mass:
    13059 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF6 Gene

Post-translational modifications for IQCF6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCF6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCF6 Gene

Domains & Families for IQCF6 Gene

Protein Domains for IQCF6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCF6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MYZ5

UniProtKB/Swiss-Prot:

IQCF6_HUMAN :
  • Contains 1 IQ domain.
Domain:
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCF6: view

No data available for Gene Families for IQCF6 Gene

Function for IQCF6 Gene

Gene Ontology (GO) - Molecular Function for IQCF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0005516 calmodulin binding IBA --
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with IQCF6: view

Phenotypes for IQCF6 Gene

GenomeRNAi human phenotypes for IQCF6:
genes like me logo Genes that share phenotypes with IQCF6: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF6 Gene

Localization for IQCF6 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IQCF6 gene
Compartment Confidence
mitochondrion 2
cytosol 2
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for IQCF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005737 cytoplasm ISS --
genes like me logo Genes that share ontologies with IQCF6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for IQCF6 Gene

Pathways & Interactions for IQCF6 Gene

SuperPathways for IQCF6 Gene

No Data Available

Interacting Proteins for IQCF6 Gene

Gene Ontology (GO) - Biological Process for IQCF6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter ISS --
GO:0060999 positive regulation of dendritic spine development ISS --
genes like me logo Genes that share ontologies with IQCF6: view

No data available for Pathways by source and SIGNOR curated interactions for IQCF6 Gene

Transcripts for IQCF6 Gene

mRNA/cDNA for IQCF6 Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCF6 Gene

IQ motif containing F6:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF6 Gene

No ASD Table

Relevant External Links for IQCF6 Gene

GeneLoc Exon Structure for
IQCF6
ECgene alternative splicing isoforms for
IQCF6

Expression for IQCF6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IQCF6 Gene

mRNA differential expression in normal tissues according to GTEx for IQCF6 Gene

This gene is overexpressed in Testis (x51.7).

NURSA nuclear receptor signaling pathways regulating expression of IQCF6 Gene:

IQCF6

SOURCE GeneReport for Unigene cluster for IQCF6 Gene:

Hs.444316
genes like me logo Genes that share expression patterns with IQCF6: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IQCF6 Gene

Orthologs for IQCF6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IQCF6 34 35
  • 98.75 (n)
dog
(Canis familiaris)
Mammalia IQCF6 34 35
  • 95.28 (n)
cow
(Bos Taurus)
Mammalia IQCF6 34 35
  • 95.02 (n)
mouse
(Mus musculus)
Mammalia Iqcf6 34 16 35
  • 86.92 (n)
rat
(Rattus norvegicus)
Mammalia Iqcf6 34
  • 83.49 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 46 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 21 (a)
OneToMany
Species where no ortholog for IQCF6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF6 Gene

ENSEMBL:
Gene Tree for IQCF6 (if available)
TreeFam:
Gene Tree for IQCF6 (if available)

Paralogs for IQCF6 Gene

Paralogs for IQCF6 Gene

(4) SIMAP similar genes for IQCF6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with IQCF6: view

Variants for IQCF6 Gene

Sequence variations from dbSNP and Humsavar for IQCF6 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs11130296 -- 51,778,936(+) ACGTC(C/T)GGCGC intron-variant, reference, missense
rs112635708 -- 51,779,098(+) GGTGC(-/CCCT)CCCTG intron-variant
rs114340942 -- 51,778,189(+) CTGCC(A/G)GCCCT intron-variant, downstream-variant-500B
rs115176811 -- 51,780,789(+) AATGT(A/T)TAACT intron-variant, upstream-variant-2KB
rs116339206 -- 51,779,610(+) AGGGC(A/G)CCTGT intron-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for IQCF6 Gene

Variant ID Type Subtype PubMed ID
nsv508921 CNV insertion 20534489
nsv520211 CNV gain 19592680

Variation tolerance for IQCF6 Gene

Gene Damage Index Score: 8.02; 84.23% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCF6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IQCF6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF6 Gene

Disorders for IQCF6 Gene

Relevant External Links for IQCF6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IQCF6

No disorders were found for IQCF6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF6 Gene

Publications for IQCF6 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 64

Products for IQCF6 Gene

Sources for IQCF6 Gene

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