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Aliases for IQCF5 Gene

Aliases for IQCF5 Gene

  • IQ Motif Containing F5 2 3 5

External Ids for IQCF5 Gene

Previous GeneCards Identifiers for IQCF5 Gene

  • GC03M051883
  • GC03M051884

Summaries for IQCF5 Gene

GeneCards Summary for IQCF5 Gene

IQCF5 (IQ Motif Containing F5) is a Protein Coding gene. An important paralog of this gene is IQCF1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF5 Gene

Genomics for IQCF5 Gene

Regulatory Elements for IQCF5 Gene

Enhancers for IQCF5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F052074 0.3 FANTOM5 31.2 -199.0 -199007 0.2 CTCF NCOR1 ZMYM3 REST NR2F2 IQCF2 PHF7 IQCF5 IQCF1 IQCF6 LINC00696 POC1A
GH03F052243 1 FANTOM5 ENCODE 14.5 -370.3 -370302 4.9 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 FOS SP3 PBRM1 PPM1M LOC101929054 GLYCTK IQCF2 IQCF5 PHF7 IQCF6 IQCF1 WDR82
GH03F051902 0.2 ENCODE 11.7 -27.0 -26976 0.2 ZNF639 KLF1 SP3 JUN ZNF223 INSM2 KLF17 TSHZ1 ZNF264 FOS RRP9 IQCF5 IQCF5-AS1 RN7SL504P IQCF3 IQCF4 GPR62 PCBP4 RAD54L2 RPL29
GH03F051798 0.5 Ensembl 10.7 +76.9 76884 0.2 RAD51 USF1 NFYB NFYC USF2 IQCF5 GC03P051793 IQCF4
GH03F051800 0.8 ENCODE 10.7 +75.4 75446 0.1 CTCF ZNF654 ZNF143 SMC3 TRIM22 RAD21 IQCF6 IQCF5 GC03P051793 IQCF4
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around IQCF5 on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCF5 Gene

51,873,721 bp from pter
51,875,584 bp from pter
1,864 bases
Minus strand

Genomic View for IQCF5 Gene

Genes around IQCF5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCF5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCF5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF5 Gene

Proteins for IQCF5 Gene

  • Protein details for IQCF5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein F5
    Protein Accession:

    Protein attributes for IQCF5 Gene

    148 amino acids
    Molecular mass:
    18048 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF5 Gene

Post-translational modifications for IQCF5 Gene

No Post-translational modifications

Other Protein References for IQCF5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCF5 Gene

Domains & Families for IQCF5 Gene

Protein Domains for IQCF5 Gene


Suggested Antigen Peptide Sequences for IQCF5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 IQ domains.
  • Contains 2 IQ domains.
genes like me logo Genes that share domains with IQCF5: view

No data available for Gene Families for IQCF5 Gene

Function for IQCF5 Gene

Gene Ontology (GO) - Molecular Function for IQCF5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005516 calmodulin binding IBA --
genes like me logo Genes that share ontologies with IQCF5: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF5 Gene

Localization for IQCF5 Gene

Subcellular locations from

Jensen Localization Image for IQCF5 Gene COMPARTMENTS Subcellular localization image for IQCF5 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCF5 Gene

Pathways & Interactions for IQCF5 Gene

SuperPathways for IQCF5 Gene

No Data Available

Interacting Proteins for IQCF5 Gene

Gene Ontology (GO) - Biological Process for IQCF5 Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCF5 Gene

Transcripts for IQCF5 Gene

mRNA/cDNA for IQCF5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCF5 Gene

IQ motif containing F5:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF5 Gene

No ASD Table

Relevant External Links for IQCF5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCF5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IQCF5 Gene

mRNA differential expression in normal tissues according to GTEx for IQCF5 Gene

This gene is overexpressed in Testis (x52.9).

NURSA nuclear receptor signaling pathways regulating expression of IQCF5 Gene:


SOURCE GeneReport for Unigene cluster for IQCF5 Gene:

genes like me logo Genes that share expression patterns with IQCF5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IQCF5 Gene

Orthologs for IQCF5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia IQCF5 34 35
  • 99.1 (n)
(Canis familiaris)
Mammalia IQCF5 34 35
  • 79.14 (n)
(Rattus norvegicus)
Mammalia Iqcf5 34
  • 77.93 (n)
(Bos Taurus)
Mammalia IQCF5 34 35
  • 77.7 (n)
(Mus musculus)
Mammalia Iqcf5 34 16 35
  • 77.48 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 39 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 28 (a)
Species where no ortholog for IQCF5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF5 Gene

Gene Tree for IQCF5 (if available)
Gene Tree for IQCF5 (if available)

Paralogs for IQCF5 Gene

Paralogs for IQCF5 Gene

(4) SIMAP similar genes for IQCF5 Gene using alignment to 1 proteins: Pseudogenes for IQCF5 Gene

genes like me logo Genes that share paralogs with IQCF5: view

Variants for IQCF5 Gene

Sequence variations from dbSNP and Humsavar for IQCF5 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1010251 -- 51,874,741(+) CCTGC(A/T)TTCCC intron-variant, nc-transcript-variant
rs111285759 -- 51,874,098(+) GCGTC(A/G)CACCA nc-transcript-variant, reference, stop-gained
rs112886560 -- 51,877,245(+) CACCA(C/T)ACCCA upstream-variant-2KB
rs11399277 -- 51,874,735(+) TTGGT(-/C)CCTGC intron-variant, nc-transcript-variant
rs115729521 -- 51,874,082(+) CTGCA(C/T)GCAGC nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for IQCF5 Gene

Variant ID Type Subtype PubMed ID
nsv3817 CNV insertion 18451855
nsv520211 CNV gain 19592680

Variation tolerance for IQCF5 Gene

Gene Damage Index Score: 1.79; 33.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCF5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF5 Gene

Disorders for IQCF5 Gene

Relevant External Links for IQCF5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IQCF5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF5 Gene

Publications for IQCF5 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4 64
  2. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T. … Xu R. (Neurobiol. Aging 2014) 3 64

Products for IQCF5 Gene

Sources for IQCF5 Gene

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