Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IQCF3 Gene

Aliases for IQCF3 Gene

  • IQ Motif Containing F3 2 3

External Ids for IQCF3 Gene

Previous GeneCards Identifiers for IQCF3 Gene

  • GC03P051826

Summaries for IQCF3 Gene

GeneCards Summary for IQCF3 Gene

IQCF3 (IQ Motif Containing F3) is a Protein Coding gene. An important paralog of this gene is IQCF5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF3 Gene

Genomics for IQCF3 Gene

Regulatory Elements for IQCF3 Gene

Genomic Location for IQCF3 Gene

51,817,604 bp from pter
51,830,858 bp from pter
13,255 bases
Plus strand

Genomic View for IQCF3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCF3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF3 Gene

Proteins for IQCF3 Gene

  • Protein details for IQCF3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein F3
    Protein Accession:
    Secondary Accessions:
    • B2RUV0

    Protein attributes for IQCF3 Gene

    154 amino acids
    Molecular mass:
    18251 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF3 Gene

Proteomics data for IQCF3 Gene at MOPED

Post-translational modifications for IQCF3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCF3 Gene

No data available for DME Specific Peptides for IQCF3 Gene

Domains & Families for IQCF3 Gene

Protein Domains for IQCF3 Gene


Suggested Antigen Peptide Sequences for IQCF3 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCF3: view

No data available for Gene Families for IQCF3 Gene

Function for IQCF3 Gene

Gene Ontology (GO) - Molecular Function for IQCF3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IQCF3: view
genes like me logo Genes that share phenotypes with IQCF3: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCF3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF3 Gene

Localization for IQCF3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IQCF3 Gene

Pathways & Interactions for IQCF3 Gene

SuperPathways for IQCF3 Gene

No Data Available

Interacting Proteins for IQCF3 Gene

Gene Ontology (GO) - Biological Process for IQCF3 Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCF3 Gene

Drugs & Compounds for IQCF3 Gene

No Compound Related Data Available

Transcripts for IQCF3 Gene

Unigene Clusters for IQCF3 Gene

IQ motif containing F3:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCF3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF3 Gene

No ASD Table

Relevant External Links for IQCF3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCF3 Gene

mRNA expression in normal human tissues for IQCF3 Gene

mRNA differential expression in normal tissues according to GTEx for IQCF3 Gene

This gene is overexpressed in Testis (x51.5).

Protein differential expression in normal tissues from HIPED for IQCF3 Gene

This gene is overexpressed in Thyroid (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCF3 Gene

SOURCE GeneReport for Unigene cluster for IQCF3 Gene Hs.729443

genes like me logo Genes that share expression patterns with IQCF3: view

Protein tissue co-expression partners for IQCF3 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCF3 Gene

Orthologs for IQCF3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IQCF3 35
  • 74.89 (n)
  • 61.04 (a)
IQCF3 36
  • 53 (a)
(Pan troglodytes)
Mammalia IQCF3 35
  • 99.78 (n)
  • 100 (a)
IQCF3 36
  • 100 (a)
(Mus musculus)
Mammalia Iqcf3 16
Iqcf4 36
  • 24 (a)
(Canis familiaris)
Mammalia IQCF3 36
  • 58 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 28 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 26 (a)
Species with no ortholog for IQCF3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF3 Gene

Gene Tree for IQCF3 (if available)
Gene Tree for IQCF3 (if available)

Paralogs for IQCF3 Gene

Paralogs for IQCF3 Gene

(4) SIMAP similar genes for IQCF3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with IQCF3: view

Variants for IQCF3 Gene

Sequence variations from dbSNP and Humsavar for IQCF3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs6782139 -- 51,825,814(+) ttcta(A/C)acata upstream-variant-2KB
rs6788189 -- 51,827,890(+) ttccc(A/G)cttct intron-variant
rs6795223 -- 51,829,910(+) GATAG(G/T)TGGGG intron-variant
rs6798175 -- 51,828,260(+) tcaag(C/G)ggaat intron-variant
rs6802583 -- 51,827,931(+) ttcct(A/G)tgttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCF3 Gene

Variant ID Type Subtype PubMed ID
nsv520211 CNV Gain 19592680

Variation tolerance for IQCF3 Gene

Residual Variation Intolerance Score: 88.84% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.20; 4.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCF3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF3 Gene

Disorders for IQCF3 Gene

Relevant External Links for IQCF3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with IQCF3: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF3 Gene

Publications for IQCF3 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for IQCF3 Gene

Sources for IQCF3 Gene

Back to Top