IQCF3 Gene
protein-coding GIFtS: 34
GCID: GC03P051856
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IQ motif containing F3
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Aliases
for IQCF3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
|---|
| IQ Motif Containing F31 2 | | IQ Domain-Containing Protein F32 |
Export aliases for IQCF3 gene to outside databasesPrevious GC identifer: GC03P051826 |
Summaries
for IQCF3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for IQCF3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IQCF3 gene promoter:
NF-1 NF-1/L p53 Arnt NF-AT AREB6 NF-AT4 NF-AT2 NF-AT3 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for IQCF3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCF3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.2 Ensembl cytogenetic band: 3p21.2 HGNC cytogenetic band: 3p21.31IQCF3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P051856: view genomic region
(about GC identifiers)
Start:
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51,851,620 bp from pter |
End:
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51,864,876 bp from pter |
Size:
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13,257 bases |
Orientation:
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plus strand |
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Proteins
for IQCF3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: IQCF3_HUMAN, P0C7M6 (See
protein sequence)Recommended Name: IQ domain-containing protein F3 Size: 154 amino acids; 18251 DaExplore the universe of human proteins at neXtProt for IQCF3: NX_P0C7M6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0C7M6
IQCF3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001078948.1 NP_001193952.1
ENSEMBL proteins: ENSP00000415609 ENSP00000409373 ENSP00000401767 ENSP00000402530 ENSP00000402012
Human Recombinant Protein Products:
IQCF3 Antibody Products:
Assay Products for IQCF3: |
Protein
Domains /
Families
for IQCF3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IQCF3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P0C7M6ProtoNet protein and cluster: P0C7M6 UniProtKB/Swiss-Prot: IQCF3_HUMAN, P0C7M6Similarity: Contains 1 IQ domain |
Function
for IQCF3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IQCF3 (NM_001085479) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCF3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF3 |
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Pathways & Interactions
for IQCF3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IQCF3
|
Drugs & Compounds
for IQCF3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IQCF3
Search CenterWatch for drugs/clinical trials and news about IQCF3
|
Transcripts
for IQCF3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for IQCF3 gene (2 alternative transcripts): NM_001085479.2 NM_001207023.1 Unigene Cluster for IQCF3: IQ motif containing F3 Hs.729443 [show with all ESTs]Unigene Representative Sequence: NM_0010854799 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000456080(uc021wyy.1 uc021wyz.1) ENST00000437810 ENST00000446775
ENST00000472485 ENST00000465028 ENST00000474242 ENST00000444293 ENST00000462079
ENST00000440739
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IQCF3 (NM_001085479) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCF3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF3 |
Additional cDNA sequence: BC021188.2 BC146874.1 BC146889.1 BC171811.1 BC171818.1 2 DOTS entries: DT.408459 DT.95260709 24/30 AceView cDNA sequences (see all 30): AI024944 BX643092 BE467881 AA991812 AA383334 AA394104 BC021188 AA460144 BI829946 AA398133 AA453974 BE551679 AW449917 AA453469 AA460742 AI651900 AK057432 BX101258 AW592364 AA992611 AI694420 AA910466 AA405042 AW291394
GeneLoc Exon Structure
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Expression
for IQCF3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IQCF3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAACAGGC
About this image
See IQCF3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IQCF3
SOURCE GeneReport for Unigene cluster: Hs.729443
SABiosciences Custom PCR Arrays for IQCF3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCF3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IQCF3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCF3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCF3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF3 |
Orthologs
for IQCF3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for IQCF3 (if available)
TreeFam Gene Tree for IQCF3 (if available) |
Paralogs
for IQCF3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IQCF3 gene
- IQCF62 IQCF52 IQCF12 IQCF22
4 SIMAP similar genes for IQCF3 using alignment to 3 protein entries: IQCF3_HUMAN (see all proteins):IQCF6 IQCF2 IQCF5 IQCF1
IQCF3 for paralogs About GeneDecksing
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Genomic Variants
for IQCF3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for IQCF3 (51851620 - 51864876 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IQCF3: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCF3 |
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Disorders
/ Diseases
for IQCF3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for IQCF3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IQCF3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IQCF3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for IQCF3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing IQCF3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing IQCF3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IQCF3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IQCF3 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for IQCF3 gene:
Search GeneIP for patents involving IQCF3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IQCF3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IQCF3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IQCF3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCF3 | | | OriGene Protein Over-expression Lysate for IQCF3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IQCF3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IQCF3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCF3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCF3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IQCF3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCF3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCF3 |
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| | | | Search Tocris compounds for IQCF3 |
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 | | | IQCF3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF3 |
|  |  |  | | | | Search ThermoFisher Antibodies for IQCF3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF3 |
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