Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IQCF2 Gene

Aliases for IQCF2 Gene

  • IQ Motif Containing F2 2 3 5

External Ids for IQCF2 Gene

Previous GeneCards Identifiers for IQCF2 Gene

  • GC03P051870
  • GC03P051895

Summaries for IQCF2 Gene

GeneCards Summary for IQCF2 Gene

IQCF2 (IQ Motif Containing F2) is a Protein Coding gene. An important paralog of this gene is IQCF5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCF2 Gene

Genomics for IQCF2 Gene

Regulatory Elements for IQCF2 Gene

Enhancers for IQCF2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around IQCF2 on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCF2 Gene

Chromosome:
3
Start:
51,861,629 bp from pter
End:
51,863,424 bp from pter
Size:
1,796 bases
Orientation:
Plus strand

Genomic View for IQCF2 Gene

Genes around IQCF2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCF2 Gene

Proteins for IQCF2 Gene

  • Protein details for IQCF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXL9-IQCF2_HUMAN
    Recommended name:
    IQ domain-containing protein F2
    Protein Accession:
    Q8IXL9

    Protein attributes for IQCF2 Gene

    Size:
    164 amino acids
    Molecular mass:
    19627 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IQCF2 Gene

Proteomics data for IQCF2 Gene at MOPED

Post-translational modifications for IQCF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCF2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCF2 Gene

Domains & Families for IQCF2 Gene

Protein Domains for IQCF2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCF2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IXL9

UniProtKB/Swiss-Prot:

IQCF2_HUMAN :
  • Contains 2 IQ domains.
Domain:
  • Contains 2 IQ domains.
genes like me logo Genes that share domains with IQCF2: view

No data available for Gene Families for IQCF2 Gene

Function for IQCF2 Gene

Phenotypes for IQCF2 Gene

GenomeRNAi human phenotypes for IQCF2:
genes like me logo Genes that share phenotypes with IQCF2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IQCF2 Gene

Localization for IQCF2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IQCF2 Gene COMPARTMENTS Subcellular localization image for IQCF2 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCF2 Gene

Pathways & Interactions for IQCF2 Gene

SuperPathways for IQCF2 Gene

No Data Available

Interacting Proteins for IQCF2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000329904%0d%0a9606.ENSP00000381298%0d%0a
Selected Interacting proteins: Q8IXL9-IQCF2_HUMAN ENSP00000329904 for IQCF2 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for IQCF2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for IQCF2 Gene

Drugs & Compounds for IQCF2 Gene

No Compound Related Data Available

Transcripts for IQCF2 Gene

mRNA/cDNA for IQCF2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IQCF2 Gene

IQ motif containing F2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IQCF2 Gene

No ASD Table

Relevant External Links for IQCF2 Gene

GeneLoc Exon Structure for
IQCF2
ECgene alternative splicing isoforms for
IQCF2

Expression for IQCF2 Gene

mRNA expression in normal human tissues for IQCF2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IQCF2 Gene

This gene is overexpressed in Testis (x52.9).

SOURCE GeneReport for Unigene cluster for IQCF2 Gene Hs.412294

genes like me logo Genes that share expression patterns with IQCF2: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IQCF2 Gene

Orthologs for IQCF2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCF2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia IQCF2 35
  • 78.12 (n)
  • 70.55 (a)
IQCF2 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCF2 35
  • 80.45 (n)
  • 72.22 (a)
IQCF2 36
  • 73 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia IQCF2 35
  • 99.8 (n)
  • 99.39 (a)
IQCF2 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Iqcf2 35
  • 80.44 (n)
  • 72.73 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 31 (a)
OneToMany
Species with no ortholog for IQCF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IQCF2 Gene

ENSEMBL:
Gene Tree for IQCF2 (if available)
TreeFam:
Gene Tree for IQCF2 (if available)

Paralogs for IQCF2 Gene

Paralogs for IQCF2 Gene

(4) SIMAP similar genes for IQCF2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with IQCF2: view

Variants for IQCF2 Gene

Sequence variations from dbSNP and Humsavar for IQCF2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2311060 -- 51,861,313(+) GCCCT(A/T)AAAAG upstream-variant-2KB
rs2311061 -- 51,861,314(+) CCCTA(A/T)AAAGG upstream-variant-2KB
rs2007607 -- 51,861,244(+) CCCCC(A/G)ACTCT upstream-variant-2KB
rs986539 -- 51,861,834(+) ATGTA(C/T)TTCCC intron-variant
rs7614309 -- 51,861,499(+) GTACA(A/T)GTTCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for IQCF2 Gene

Variant ID Type Subtype PubMed ID
nsv520211 CNV Gain 19592680
nsv3817 CNV Insertion 18451855

Variation tolerance for IQCF2 Gene

Residual Variation Intolerance Score: 78.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.06; 37.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCF2 Gene

HapMap Linkage Disequilibrium report
IQCF2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCF2 Gene

Disorders for IQCF2 Gene

Relevant External Links for IQCF2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IQCF2

No disorders were found for IQCF2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCF2 Gene

Publications for IQCF2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for IQCF2 Gene

Sources for IQCF2 Gene

Content