IQCF1 Gene
protein-coding GIFtS: 39
GCID: GC03M051928
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IQ motif containing F1
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Aliases
for IQCF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| IQ Motif Containing F11 2 | | MGC397251 | | IQ Domain-Containing Protein F12 |
Export aliases for IQCF1 gene to outside databasesPrevious GC identifers: GC03M051818 GC03M051903 GC03M051843 |
Summaries
for IQCF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for IQCF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IQCF1 gene promoter:
c-Fos AP-1 Bach2 JunB Fra-1 FosB MyoD POU2F2C JunD c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for IQCF1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCF1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.2 Ensembl cytogenetic band: 3p21.2 HGNC cytogenetic band: 3p21.31IQCF1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M051928: view genomic region
(about GC identifiers)
Start:
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51,928,892 bp from pter |
End:
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51,937,386 bp from pter |
Size:
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8,495 bases |
Orientation:
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minus strand |
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Proteins
for IQCF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IQCF1_HUMAN, Q8N6M8 (See
protein sequence)Recommended Name: IQ domain-containing protein F1 Size: 205 amino acids; 23699 Da
Secondary accessions: Q8N711Alternative splicing: 2 isoforms: Q8N6M8-1 Q8N6M8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IQCF1: NX_Q8N6M8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N6M8
IQCF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689610.2
ENSEMBL proteins: ENSP00000307958 ENSP00000317715
Human Recombinant Protein Products:
IQCF1 Antibody Products:
Assay Products for IQCF1: |
Protein
Domains /
Families
for IQCF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IQCF1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N6M8ProtoNet protein and cluster: Q8N6M8 UniProtKB/Swiss-Prot: IQCF1_HUMAN, Q8N6M8Similarity: Contains 2 IQ domains |
Function
for IQCF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IQCF1 (NM_152397) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF1 |
2 GenomeRNAi human phenotypes for IQCF1:
|
Pathways & Interactions
for IQCF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IQCF1
|
Drugs & Compounds
for IQCF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IQCF1
Search CenterWatch for drugs/clinical trials and news about IQCF1
|
Transcripts
for IQCF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IQCF1 gene: NM_152397.2 Unigene Cluster for IQCF1: IQ motif containing F1 Hs.671210 [show with all ESTs]Unigene Representative Sequence: BC0342282 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000310914(uc003dbq.4 uc003dbv.3) ENST00000314534
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IQCF1 (NM_152397) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCF1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF1 |
Additional cDNA sequence: AK131018.1 BC029595.1 BC034228.1 3 DOTS entries: DT.40265443 DT.95185004 DT.97785108 12 AceView cDNA sequences: AW004079 AI825444 NM_152397 BM560164 AK131018 BC034228 AA861580 BC029595 AW593295 BI551525 BI548459 BI459409
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for IQCF1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 |
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| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for IQCF1
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Expression
for IQCF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IQCF1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATTTCACT
About this image
See IQCF1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IQCF1
SOURCE GeneReport for Unigene cluster: Hs.671210
SABiosciences Custom PCR Arrays for IQCF1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCF1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IQCF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCF1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF1 |
Orthologs
for IQCF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for IQCF1 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for IQCF1 (if available)
TreeFam Gene Tree for IQCF1 (if available) |
Paralogs
for IQCF1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IQCF1 gene
- IQCF62 IQCF52 IQCF32 IQCF22
4 SIMAP similar genes for IQCF1 using alignment to 2 protein entries: IQCF1_HUMAN (see all proteins):IQCF6 IQCF2 IQCF5 IQCF3
IQCF1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for IQCF1
PGOHUM00000239429
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Genomic Variants
for IQCF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IQCF1 (51928892 - 51937386 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IQCF1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCF1 |
|
Disorders
/ Diseases
for IQCF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for IQCF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IQCF1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IQCF1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
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External Searches for IQCF1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing IQCF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IQCF1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IQCF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IQCF1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IQCF1 gene:
Search GeneIP for patents involving IQCF1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IQCF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IQCF1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IQCF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCF1 | | | OriGene Protein Over-expression Lysate for IQCF1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IQCF1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCF1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IQCF1 | | OriGene Custom Protein Services for IQCF1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IQCF1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCF1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCF1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IQCF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCF1 |
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| | | | Search Tocris compounds for IQCF1 |
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 | | | IQCF1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCF1 |
|  |  |  | | | | Search ThermoFisher Antibodies for IQCF1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCF1 |
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