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Aliases for IQCE Gene

Aliases for IQCE Gene

  • IQ Motif Containing E 2 3
  • IQ Domain-Containing Protein E 3
  • 1700028P05Rik 3
  • KIAA1023 4

External Ids for IQCE Gene

Previous GeneCards Identifiers for IQCE Gene

  • GC07P002371
  • GC07P002565
  • GC07P002598

Summaries for IQCE Gene

GeneCards Summary for IQCE Gene

IQCE (IQ Motif Containing E) is a Protein Coding gene.

Gene Wiki entry for IQCE Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCE Gene

Genomics for IQCE Gene

Regulatory Elements for IQCE Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IQCE Gene

Start:
2,558,972 bp from pter
End:
2,614,734 bp from pter
Size:
55,763 bases
Orientation:
Plus strand

Genomic View for IQCE Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCE Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCE Gene

Proteins for IQCE Gene

  • Protein details for IQCE Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IPM2-IQCE_HUMAN
    Recommended name:
    IQ domain-containing protein E
    Protein Accession:
    Q6IPM2
    Secondary Accessions:
    • Q4G0P7
    • Q6P7T4
    • Q9H0H7
    • Q9UPX7

    Protein attributes for IQCE Gene

    Size:
    695 amino acids
    Molecular mass:
    77298 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA82975.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for IQCE Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IQCE Gene

Proteomics data for IQCE Gene at MOPED

Post-translational modifications for IQCE Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for IQCE Gene

Domains for IQCE Gene

Protein Domains for IQCE Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCE Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6IPM2

UniProtKB/Swiss-Prot:

IQCE_HUMAN :
  • Q6IPM2
Domain:
  • Contains 2 IQ domains.
genes like me logo Genes that share domains with IQCE: view

No data available for Gene Families for IQCE Gene

Function for IQCE Gene

Gene Ontology (GO) - Molecular Function for IQCE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with IQCE: view

Animal Model Products

CRISPR Products

miRNA for IQCE Gene

miRTarBase miRNAs that target IQCE

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for IQCE Gene

Localization for IQCE Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IQCE Gene COMPARTMENTS Subcellular localization image for IQCE gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 2

Gene Ontology (GO) - Cellular Components for IQCE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0072372 primary cilium TAS --
genes like me logo Genes that share ontologies with IQCE: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for IQCE Gene

Pathways for IQCE Gene

SuperPathways for IQCE Gene

No Data Available

Gene Ontology (GO) - Biological Process for IQCE Gene

None

No data available for Pathways by source for IQCE Gene

Transcripts for IQCE Gene

Unigene Clusters for IQCE Gene

IQ motif containing E:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCE

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for IQCE

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCE Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^
SP1: - - - - - -
SP2: - - - - - -
SP3: - - - - - - - -
SP4: - - - - - -
SP5: -
SP6:
SP7:
SP8: -
SP9: - -

ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26a · 26b · 26c ^ 27a · 27b
SP1: - - -
SP2: -
SP3: - - -
SP4:
SP5:
SP6: -
SP7:
SP8:
SP9:

Relevant External Links for IQCE Gene

GeneLoc Exon Structure for
IQCE
ECgene alternative splicing isoforms for
IQCE

Expression for IQCE Gene

mRNA expression in normal human tissues for IQCE Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for IQCE Gene

SOURCE GeneReport for Unigene cluster for IQCE Gene Hs.520627

genes like me logo Genes that share expressions with IQCE: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for IQCE Gene

Orthologs for IQCE Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCE Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IQCE 35
  • 99.18 (n)
  • 98.42 (a)
IQCE 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia IQCE 35
  • 75.19 (n)
  • 68.42 (a)
IQCE 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCE 35
  • 76.29 (n)
  • 70.95 (a)
IQCE 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Iqce 35
  • 74.15 (n)
  • 67.48 (a)
Iqce 16
Iqce 36
  • 58 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IQCE 36
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia IQCE 36
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Iqce 35
  • 74.1 (n)
  • 66.72 (a)
chicken
(Gallus gallus)
Aves IQCE 35
  • 58.49 (n)
  • 48.63 (a)
IQCE 36
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IQCE 36
  • 45 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia iqce 35
  • 53.85 (n)
  • 45.48 (a)
zebrafish
(Danio rerio)
Actinopterygii iqce 35
  • 49.79 (n)
  • 41.12 (a)
iqce 36
  • 33 (a)
OneToOne
Species with no ortholog for IQCE:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCE Gene

ENSEMBL:
Gene Tree for IQCE (if available)
TreeFam:
Gene Tree for IQCE (if available)

Paralogs for IQCE Gene

No data available for Paralogs for IQCE Gene

Variants for IQCE Gene

Sequence variations from dbSNP and Humsavar for IQCE Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs930355 -- 2,597,430(-) TTCAT(C/T)TTCTG intron-variant
rs1036504 -- 2,570,131(+) CAGCT(C/T)CCACC intron-variant
rs1045711 -- 2,613,937(+) GGGCC(C/T)GGTGT utr-variant-3-prime, nc-transcript-variant
rs1045713 -- 2,613,945(+) TGTTG(A/G)ACAAA utr-variant-3-prime, nc-transcript-variant
rs1045714 -- 2,613,948(+) TGGAC(A/G)AAGTA utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCE Gene

Variant ID Type Subtype PubMed ID
dgv7116n71 CNV Loss 21882294
dgv7117n71 CNV Loss 21882294
dgv7118n71 CNV Loss 21882294
dgv7119n71 CNV Loss 21882294
nsv830887 CNV Loss 17160897
nsv887297 CNV Loss 21882294
nsv887298 CNV Loss 21882294
esv1553581 CNV Deletion 17803354
esv2733858 CNV Deletion 23290073
nsv887300 CNV Loss 21882294
esv2349098 CNV Deletion 18987734
nsv471227 CNV Loss 18288195
esv994621 CNV Insertion 20482838
esv1234995 CNV Insertion 17803354
esv2733859 CNV Deletion 23290073
esv2357458 CNV Deletion 18987734
esv2733860 CNV Deletion 23290073
esv2733862 CNV Deletion 23290073
esv1223273 CNV Deletion 17803354
nsv887301 CNV Loss 21882294
dgv401n21 CNV Loss 19592680
dgv7121n71 CNV Loss 21882294
nsv823982 CNV Gain 20364138
nsv887303 CNV Loss 21882294
dgv7122n71 CNV Loss 21882294

Relevant External Links for IQCE Gene

HapMap Linkage Disequilibrium report
IQCE
Human Gene Mutation Database (HGMD)
IQCE

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCE Gene

Disorders for IQCE Gene

Relevant External Links for IQCE

Genetic Association Database (GAD)
IQCE
Human Genome Epidemiology (HuGE) Navigator
IQCE
genes like me logo Genes that share disorders with IQCE: view

No data available for UniProtKB/Swiss-Prot for IQCE Gene

Publications for IQCE Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 2 3 4
  2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48
  3. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for IQCE Gene

Sources for IQCE Gene

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