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Aliases for IQCD Gene

Aliases for IQCD Gene

  • IQ Motif Containing D 2 3
  • Dynein Regulatory Complex Subunit 10 2 3
  • 4933433C09Rik 3
  • CFAP84 3
  • DRC10 3

External Ids for IQCD Gene

Previous GeneCards Identifiers for IQCD Gene

  • GC12M112095
  • GC12M112117
  • GC12M113633
  • GC12M110645

Summaries for IQCD Gene

GeneCards Summary for IQCD Gene

IQCD (IQ Motif Containing D) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCD Gene

Genomics for IQCD Gene

Regulatory Elements for IQCD Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IQCD Gene

113,195,441 bp from pter
113,221,094 bp from pter
25,654 bases
Minus strand

Genomic View for IQCD Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCD Gene

Proteins for IQCD Gene

  • Protein details for IQCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein D
    Protein Accession:
    Secondary Accessions:
    • Q6ZSU0

    Protein attributes for IQCD Gene

    449 amino acids
    Molecular mass:
    52359 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IQCD Gene


neXtProt entry for IQCD Gene

Proteomics data for IQCD Gene at MOPED

Post-translational modifications for IQCD Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCD Gene

Domains & Families for IQCD Gene

Gene Families for IQCD Gene

Protein Domains for IQCD Gene


Suggested Antigen Peptide Sequences for IQCD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCD: view

Function for IQCD Gene

Gene Ontology (GO) - Molecular Function for IQCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IQCD: view
genes like me logo Genes that share phenotypes with IQCD: view

Animal Model Products

miRNA for IQCD Gene

miRTarBase miRNAs that target IQCD

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCD

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for IQCD Gene

Localization for IQCD Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IQCD Gene

Pathways & Interactions for IQCD Gene

SuperPathways for IQCD Gene

No Data Available

Interacting Proteins for IQCD Gene

Gene Ontology (GO) - Biological Process for IQCD Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCD Gene

Drugs & Compounds for IQCD Gene

No Compound Related Data Available

Transcripts for IQCD Gene

mRNA/cDNA for IQCD Gene

Unigene Clusters for IQCD Gene

IQ motif containing D:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCD

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCD Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
SP1: -
SP2: -
SP3: - - - - - - -
SP5: - -

Relevant External Links for IQCD Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCD Gene

mRNA expression in normal human tissues for IQCD Gene

mRNA differential expression in normal tissues according to GTEx for IQCD Gene

This gene is overexpressed in Testis (x20.0).

Protein differential expression in normal tissues from HIPED for IQCD Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCD Gene

SOURCE GeneReport for Unigene cluster for IQCD Gene Hs.568276

genes like me logo Genes that share expression patterns with IQCD: view

Protein tissue co-expression partners for IQCD Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCD Gene

Orthologs for IQCD Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCD Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IQCD 35
  • 75.28 (n)
  • 66.46 (a)
  • 51 (a)
(Canis familiaris)
Mammalia IQCD 35
  • 79.61 (n)
  • 72.9 (a)
  • 55 (a)
(Mus musculus)
Mammalia Iqcd 35
  • 61 (n)
  • 49 (a)
Iqcd 16
Iqcd 36
  • 45 (a)
(Pan troglodytes)
Mammalia IQCD 35
  • 98.17 (n)
  • 97.25 (a)
  • 76 (a)
(Monodelphis domestica)
Mammalia IQCD 36
  • 39 (a)
(Gallus gallus)
Aves IQCD 35
  • 52.62 (n)
  • 38.21 (a)
  • 27 (a)
(Anolis carolinensis)
Reptilia IQCD 36
  • 22 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia iqcd 35
  • 48.33 (n)
  • 38.91 (a)
(Danio rerio)
Actinopterygii iqcd 35
  • 47.12 (n)
  • 35.61 (a)
iqcd 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
Species with no ortholog for IQCD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCD Gene

Gene Tree for IQCD (if available)
Gene Tree for IQCD (if available)

Paralogs for IQCD Gene

No data available for Paralogs for IQCD Gene

Variants for IQCD Gene

Sequence variations from dbSNP and Humsavar for IQCD Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs936389 -- 113,210,105(-) AGGCC(A/G)GAGTA intron-variant, utr-variant-5-prime
rs2007368 -- 113,209,946(-) GTTTC(A/G)CCATG intron-variant
rs3741989 -- 113,208,505(+) AGACA(C/G)CATTC intron-variant, utr-variant-5-prime
rs3741990 -- 113,208,239(-) TAAAA(G/T)CACGA utr-variant-5-prime, intron-variant
rs3741991 -- 113,208,231(-) CGAGA(C/T)CCAAG utr-variant-5-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCD Gene

Variant ID Type Subtype PubMed ID
nsv519540 CNV Gain+Loss 19592680
nsv899527 CNV Loss 21882294
nsv899528 CNV Loss 21882294
nsv899530 CNV Gain 21882294

Variation tolerance for IQCD Gene

Residual Variation Intolerance Score: 60.42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.95; 49.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCD Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCD Gene

Disorders for IQCD Gene

Relevant External Links for IQCD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with IQCD: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCD Gene

Publications for IQCD Gene

  1. Chromosome-centric human proteome project: deciphering proteins associated with glioma and neurodegenerative disorders on chromosome 12. (PMID: 24804578) Gupta M.K. … Sirdeshmukh R. (J. Proteome Res. 2014) 2 67
  2. The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. (PMID: 23427265) Bower R. … Porter M.E. (Mol. Biol. Cell 2013) 2 67
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  4. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 67
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 67

Products for IQCD Gene

Sources for IQCD Gene

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