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Aliases for IQCD Gene

Aliases for IQCD Gene

  • IQ Motif Containing D 2 3 5
  • Dynein Regulatory Complex Subunit 10 2 3
  • 4933433C09Rik 3
  • CFAP84 3
  • DRC10 3

External Ids for IQCD Gene

Previous GeneCards Identifiers for IQCD Gene

  • GC12M112095
  • GC12M112117
  • GC12M113633
  • GC12M110645

Summaries for IQCD Gene

GeneCards Summary for IQCD Gene

IQCD (IQ Motif Containing D) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCD Gene

Genomics for IQCD Gene

Regulatory Elements for IQCD Gene

Enhancers for IQCD Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around IQCD on UCSC Golden Path with GeneCards custom track

Promoters for IQCD Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around IQCD on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCD Gene

Chromosome:
12
Start:
113,195,441 bp from pter
End:
113,221,094 bp from pter
Size:
25,654 bases
Orientation:
Minus strand

Genomic View for IQCD Gene

Genes around IQCD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCD Gene

Proteins for IQCD Gene

  • Protein details for IQCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96DY2-IQCD_HUMAN
    Recommended name:
    IQ domain-containing protein D
    Protein Accession:
    Q96DY2
    Secondary Accessions:
    • Q6ZSU0

    Protein attributes for IQCD Gene

    Size:
    449 amino acids
    Molecular mass:
    52359 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IQCD Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IQCD Gene

Proteomics data for IQCD Gene at MOPED

Post-translational modifications for IQCD Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IQCD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCD Gene

Domains & Families for IQCD Gene

Gene Families for IQCD Gene

Protein Domains for IQCD Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96DY2

UniProtKB/Swiss-Prot:

IQCD_HUMAN :
  • Contains 1 IQ domain.
Domain:
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCD: view

Function for IQCD Gene

genes like me logo Genes that share phenotypes with IQCD: view

Animal Model Products

miRNA for IQCD Gene

miRTarBase miRNAs that target IQCD

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IQCD Gene

Localization for IQCD Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IQCD Gene COMPARTMENTS Subcellular localization image for IQCD gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCD Gene

Pathways & Interactions for IQCD Gene

SuperPathways for IQCD Gene

No Data Available

Interacting Proteins for IQCD Gene

Selected Interacting proteins: Q96DY2-IQCD_HUMAN for IQCD Gene via I2D

Gene Ontology (GO) - Biological Process for IQCD Gene

None

No data available for Pathways by source and SIGNOR curated interactions for IQCD Gene

Drugs & Compounds for IQCD Gene

No Compound Related Data Available

Transcripts for IQCD Gene

mRNA/cDNA for IQCD Gene

Unigene Clusters for IQCD Gene

IQ motif containing D:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IQCD Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
SP1: -
SP2: -
SP3: - - - - - - -
SP4:
SP5: - -

Relevant External Links for IQCD Gene

GeneLoc Exon Structure for
IQCD
ECgene alternative splicing isoforms for
IQCD

Expression for IQCD Gene

mRNA expression in normal human tissues for IQCD Gene

mRNA differential expression in normal tissues according to GTEx for IQCD Gene

This gene is overexpressed in Testis (x20.0).

Protein differential expression in normal tissues from HIPED for IQCD Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCD Gene



SOURCE GeneReport for Unigene cluster for IQCD Gene Hs.568276

genes like me logo Genes that share expression patterns with IQCD: view

Protein tissue co-expression partners for IQCD Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCD Gene

Orthologs for IQCD Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCD Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia IQCD 35
  • 75.28 (n)
  • 66.46 (a)
IQCD 36
  • 51 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCD 35
  • 79.61 (n)
  • 72.9 (a)
IQCD 36
  • 55 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Iqcd 35
  • 61 (n)
  • 49 (a)
Iqcd 16
Iqcd 36
  • 45 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia IQCD 35
  • 98.17 (n)
  • 97.25 (a)
IQCD 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia IQCD 36
  • 39 (a)
OneToOne
chicken
(Gallus gallus)
Aves IQCD 35
  • 52.62 (n)
  • 38.21 (a)
IQCD 36
  • 27 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia IQCD 36
  • 22 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia iqcd 35
  • 48.33 (n)
  • 38.91 (a)
zebrafish
(Danio rerio)
Actinopterygii iqcd 35
  • 47.12 (n)
  • 35.61 (a)
iqcd 36
  • 25 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToOne
Species with no ortholog for IQCD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCD Gene

ENSEMBL:
Gene Tree for IQCD (if available)
TreeFam:
Gene Tree for IQCD (if available)

Paralogs for IQCD Gene

No data available for Paralogs for IQCD Gene

Variants for IQCD Gene

Sequence variations from dbSNP and Humsavar for IQCD Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs7966313 - 113,207,761(+) CTGCA(C/G)CTCTA intron-variant, reference, missense
rs2007368 -- 113,209,946(-) GTTTC(A/G)CCATG intron-variant
rs7139373 -- 113,201,151(+) AAAAA(A/C/G)CAACT intron-variant
rs7297727 -- 113,205,232(+) ttttt(A/T)aaaaa intron-variant
rs7298260 -- 113,202,000(+) TTTGA(C/G)CCCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCD Gene

Variant ID Type Subtype PubMed ID
nsv519540 CNV Gain+Loss 19592680
nsv899527 CNV Loss 21882294
nsv899528 CNV Loss 21882294
nsv899530 CNV Gain 21882294

Variation tolerance for IQCD Gene

Residual Variation Intolerance Score: 60.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.95; 49.26% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for IQCD Gene

Disorders for IQCD Gene

Relevant External Links for IQCD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IQCD

No disorders were found for IQCD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCD Gene

Publications for IQCD Gene

  1. Chromosome-centric human proteome project: deciphering proteins associated with glioma and neurodegenerative disorders on chromosome 12. (PMID: 24804578) Gupta M.K. … Sirdeshmukh R. (J. Proteome Res. 2014) 2 3 67
  2. The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. (PMID: 23427265) Bower R. … Porter M.E. (Mol. Biol. Cell 2013) 2 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3

Products for IQCD Gene

Sources for IQCD Gene

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