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Aliases for IQCD Gene

Aliases for IQCD Gene

  • IQ Motif Containing D 2 3 5
  • Dynein Regulatory Complex Subunit 10 2 3
  • IQ Domain-Containing Protein D 3
  • 4933433C09Rik 3
  • CFAP84 3
  • DRC10 3

External Ids for IQCD Gene

Previous GeneCards Identifiers for IQCD Gene

  • GC12M112095
  • GC12M112117
  • GC12M113633
  • GC12M110645

Summaries for IQCD Gene

GeneCards Summary for IQCD Gene

IQCD (IQ Motif Containing D) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCD Gene

Genomics for IQCD Gene

Regulatory Elements for IQCD Gene

Enhancers for IQCD Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F113235 1.3 Ensembl ENCODE 12 -21.3 -21302 13.4 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 ZNF2 YY1 FOS ZNF263 RITA1 RASAL1 IQCD TPCN1 DDX54 ENSG00000201208 PLBD2 ENSG00000277566
GH12F113192 1.2 Ensembl ENCODE 12.8 +26.7 26675 3.6 ELF3 ZNF76 THRB RARA ZNF121 GLIS2 ZNF366 SCRT2 FOS EGR2 TPCN1 IQCD RITA1 SDSL ENSG00000257286 GC12M113206
GH12F113196 1 Ensembl ENCODE 12.8 +23.9 23894 0.8 CTCF WRNIP1 SIN3A ZNF384 RAD21 ZNF121 ZNF664 POLR2A GATAD1 ZNF143 IQCD TPCN1 RITA1 SDSL ENSG00000257286 GC12M113206
GH12F113325 0.9 Ensembl ENCODE 11.3 -105.4 -105406 2.2 CTCF ZMYM3 MNT ZNF48 NR2F2 POLR2A ADNP ZBTB33 KDM1A NFE2 PLBD2 IQCD TPCN1 GC12M113308
GH12F113251 0.5 ENCODE 12 -31.1 -31078 1.3 ZNF146 SCRT2 CEBPB RITA1 RASAL1 TPCN1 IQCD DDX54 ENSG00000201208 PLBD2 ENSG00000277566 GC12M113256
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IQCD on UCSC Golden Path with GeneCards custom track

Promoters for IQCD Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000171779 -1006 3001 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS

Genomic Location for IQCD Gene

113,195,441 bp from pter
113,221,094 bp from pter
25,654 bases
Minus strand

Genomic View for IQCD Gene

Genes around IQCD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCD Gene

Proteins for IQCD Gene

  • Protein details for IQCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein D
    Protein Accession:
    Secondary Accessions:
    • Q6ZSU0

    Protein attributes for IQCD Gene

    449 amino acids
    Molecular mass:
    52359 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for IQCD Gene


neXtProt entry for IQCD Gene

Post-translational modifications for IQCD Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for IQCD Gene

Domains & Families for IQCD Gene

Gene Families for IQCD Gene

Protein Domains for IQCD Gene


Suggested Antigen Peptide Sequences for IQCD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCD: view

Function for IQCD Gene

genes like me logo Genes that share phenotypes with IQCD: view

Animal Model Products

miRNA for IQCD Gene

miRTarBase miRNAs that target IQCD

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IQCD Gene

Localization for IQCD Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for IQCD gene
Compartment Confidence
cytosol 2
mitochondrion 1
nucleus 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCD Gene

Pathways & Interactions for IQCD Gene

No Data Available

Interacting Proteins for IQCD Gene

Gene Ontology (GO) - Biological Process for IQCD Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCD Gene

Transcripts for IQCD Gene

mRNA/cDNA for IQCD Gene

Unigene Clusters for IQCD Gene

IQ motif containing D:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCD Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7
SP1: -
SP2: -
SP3: - - - - - - -
SP5: - -

Relevant External Links for IQCD Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IQCD Gene

mRNA differential expression in normal tissues according to GTEx for IQCD Gene

This gene is overexpressed in Testis (x20.0).

Protein differential expression in normal tissues from HIPED for IQCD Gene

This gene is overexpressed in Pancreas (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCD Gene

Protein tissue co-expression partners for IQCD Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of IQCD Gene:


SOURCE GeneReport for Unigene cluster for IQCD Gene:

genes like me logo Genes that share expression patterns with IQCD: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCD Gene

Orthologs for IQCD Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCD Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia IQCD 34 35
  • 98.17 (n)
(Canis familiaris)
Mammalia IQCD 34 35
  • 79.61 (n)
(Bos Taurus)
Mammalia IQCD 34 35
  • 75.28 (n)
(Mus musculus)
Mammalia Iqcd 34 16 35
  • 61 (n)
(Monodelphis domestica)
Mammalia IQCD 35
  • 39 (a)
(Gallus gallus)
Aves IQCD 34 35
  • 52.62 (n)
(Anolis carolinensis)
Reptilia IQCD 35
  • 22 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia iqcd 34
  • 48.33 (n)
(Danio rerio)
Actinopterygii iqcd 34 35
  • 47.12 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 24 (a)
Species where no ortholog for IQCD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCD Gene

Gene Tree for IQCD (if available)
Gene Tree for IQCD (if available)

Paralogs for IQCD Gene

No data available for Paralogs for IQCD Gene

Variants for IQCD Gene

Sequence variations from dbSNP and Humsavar for IQCD Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10850132 -- 113,220,961(+) ATCTC(C/T)CCCGA intron-variant, upstream-variant-2KB
rs11066511 -- 113,201,371(+) tttgt(C/T)tgacc intron-variant
rs11066512 -- 113,201,512(+) CCCAG(C/T)TGGCA intron-variant
rs11066513 -- 113,207,608(+) TATCA(A/G)GCTGT intron-variant, reference, synonymous-codon
rs11066515 -- 113,212,952(+) GCTGA(G/T)GAACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCD Gene

Variant ID Type Subtype PubMed ID
esv3630792 CNV gain 21293372
esv3892265 CNV gain 25118596
nsv519540 CNV gain+loss 19592680

Variation tolerance for IQCD Gene

Residual Variation Intolerance Score: 60.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.95; 49.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCD Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCD Gene

Disorders for IQCD Gene

Relevant External Links for IQCD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IQCD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCD Gene

Publications for IQCD Gene

  1. Chromosome-centric human proteome project: deciphering proteins associated with glioma and neurodegenerative disorders on chromosome 12. (PMID: 24804578) Gupta M.K. … Sirdeshmukh R. (J. Proteome Res. 2014) 2 3 64
  2. The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. (PMID: 23427265) Bower R. … Porter M.E. (Mol. Biol. Cell 2013) 2 3 64
  3. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for IQCD Gene

Sources for IQCD Gene

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