IQCC Gene
protein-coding GIFtS: 40
GCID: GC01P032671
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IQ motif containing C
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Aliases
for IQCC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| IQ Motif Containing C1 2 | | FLJ105471 | | RP4-622L5.62 | | IQ Domain-Containing Protein C2 |
Export aliases for IQCC gene to outside databasesPrevious GC identifers: GC01P032340 GC01P032443 GC01P030787 |
Summaries
for IQCC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for IQCC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IQCC gene promoter:
Pax-3 NF-1 POU2F1 POU2F1a STAT3 HSF1short HSF1 (long) Hand1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for IQCC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11-p34.2 Ensembl cytogenetic band: 1p35.1 HGNC cytogenetic band: 1p36.11-p34.2IQCC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P032671: view genomic region
(about GC identifiers)
Start:
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32,671,236 bp from pter |
End:
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32,674,288 bp from pter |
Size:
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3,053 bases |
Orientation:
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plus strand |
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Proteins
for IQCC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IQCC_HUMAN, Q4KMZ1 (See
protein sequence)Recommended Name: IQ domain-containing protein C Size: 466 amino acids; 53032 Da
Sequence caution: Sequence=AK307853; Type=Erroneous termination; Positions=323; Note=Translated as Gln;
Secondary accessions: F5H7T8 Q4KMS3 Q4KMZ5 Q53FL2 Q5TFJ8 Q9NVS3Alternative splicing: 3 isoforms: Q4KMZ1-1 Q4KMZ1-2 Q4KMZ1-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IQCC: NX_Q4KMZ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q4KMZ1
IQCC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001153514.1 NP_060604.2
ENSEMBL proteins: ENSP00000291358 ENSP00000442291
Human Recombinant Protein Products:
IQCC Antibody Products:
Assay Products for IQCC: |
Protein
Domains /
Families
for IQCC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IQCC for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q4KMZ1ProtoNet protein and cluster: Q4KMZ1 UniProtKB/Swiss-Prot: IQCC_HUMAN, Q4KMZ1Similarity: Contains 1 IQ domain |
Function
for IQCC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): IQCC (NM_018134) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCC |
1 GenomeRNAi human phenotype for IQCC:
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Pathways & Interactions
for IQCC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IQCC
|
Drugs & Compounds
for IQCC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IQCC
Search CenterWatch for drugs/clinical trials and news about IQCC
|
Transcripts
for IQCC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IQCC gene (2 alternative transcripts): NM_001160042.1 NM_018134.2 Unigene Cluster for IQCC: IQ motif containing C Hs.274356 [show with all ESTs]Unigene Representative Sequence: NM_0011600422 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000291358 ENST00000537469(uc001bum.2 uc009vua.2 uc010ogz.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): IQCC (NM_018134) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IQCC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCC |
Additional cDNA sequence: AK001409.1 AK223272.1 AK299235.1 AK307853.1 BC029986.1 BC098250.1 BC098260.1 BC098317.1 BC098366.1 5 DOTS entries: DT.423309 DT.121395563 DT.97804796 DT.100657045 DT.95088175 20 AceView cDNA sequences: BX281334 AA299636 BF970007 BX348178 AI002609 CD654945 BG248100 AU127716 BF476009 AK001409 BF982159 AA299637 NM_018134 BM020291 AA188423 BX374559 CF134802 AA188725 BP344128 AU150200
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for IQCC About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 |
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| SP1: | | | | | - | | | | - | | | | | | - | | | | | | |
| SP2: | | | | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for IQCC
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Expression
for IQCC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IQCC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGAAATGAA
About this image
See IQCC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IQCC
SOURCE GeneReport for Unigene cluster: Hs.274356
SABiosciences Custom PCR Arrays for IQCC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IQCC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCC |
Orthologs
for IQCC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for IQCC gene from 4/7 species (see all 7) About this table
ENSEMBL Gene Tree for IQCC (if available)
TreeFam Gene Tree for IQCC (if available) |
Paralogs
for IQCC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for IQCC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IQCC (32671236 - 32674288 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IQCC: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCC |
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Disorders
/ Diseases
for IQCC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for IQCC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IQCC gene integrated from 9 sources:
(articles sorted by number of sources associating them with IQCC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
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External Searches for IQCC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing IQCC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IQCC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IQCC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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|
About This Section
| Patent Information for IQCC gene:
Search GeneIP for patents involving IQCC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IQCC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IQCC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IQCC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IQCC | | | OriGene Protein Over-expression Lysate for IQCC | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IQCC | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IQCC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IQCC | | OriGene Custom Protein Services for IQCC | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IQCC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IQCC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IQCC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IQCC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IQCC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IQCC |
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 |  |  |  | |
| | | | Search Tocris compounds for IQCC |
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 | | | IQCC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IQCC |
|  |  |  | | | | ThermoFisher Antibodies for IQCC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IQCC |
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