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Aliases for IQCC Gene

Aliases for IQCC Gene

  • IQ Motif Containing C 2 3

External Ids for IQCC Gene

Previous GeneCards Identifiers for IQCC Gene

  • GC01P032340
  • GC01P032443
  • GC01P032671
  • GC01P030787

Summaries for IQCC Gene

GeneCards Summary for IQCC Gene

IQCC (IQ Motif Containing C) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCC Gene

Genomics for IQCC Gene

Regulatory Elements for IQCC Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for IQCC Gene

Start:
32,205,635 bp from pter
End:
32,208,687 bp from pter
Size:
3,053 bases
Orientation:
Plus strand

Genomic View for IQCC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IQCC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCC Gene

Proteins for IQCC Gene

  • Protein details for IQCC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4KMZ1-IQCC_HUMAN
    Recommended name:
    IQ domain-containing protein C
    Protein Accession:
    Q4KMZ1
    Secondary Accessions:
    • F5H7T8
    • Q4KMS3
    • Q4KMZ5
    • Q53FL2
    • Q5TFJ8
    • Q9NVS3

    Protein attributes for IQCC Gene

    Size:
    466 amino acids
    Molecular mass:
    53032 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AK307853; Type=Erroneous termination; Positions=323; Note=Translated as Gln.; Evidence={ECO:0000305};

    Alternative splice isoforms for IQCC Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for IQCC Gene

Proteomics data for IQCC Gene at MOPED

Post-translational modifications for IQCC Gene

  • Ubiquitination at Lys127
  • Modification sites at PhosphoSitePlus

Other Protein References for IQCC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCC Gene

Domains for IQCC Gene

Protein Domains for IQCC Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for IQCC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4KMZ1

UniProtKB/Swiss-Prot:

IQCC_HUMAN :
  • Q4KMZ1
Domain:
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCC: view

No data available for Gene Families for IQCC Gene

Function for IQCC Gene

Gene Ontology (GO) - Molecular Function for IQCC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IQCC: view

Phenotypes for IQCC Gene

GenomeRNAi human phenotypes for IQCC:
genes like me logo Genes that share phenotypes with IQCC: view

Animal Model Products

CRISPR Products

miRNA for IQCC Gene

miRTarBase miRNAs that target IQCC

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for IQCC Gene

Localization for IQCC Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IQCC Gene COMPARTMENTS Subcellular localization image for IQCC gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCC Gene

Pathways for IQCC Gene

SuperPathways for IQCC Gene

No Data Available

Interacting Proteins for IQCC Gene

Gene Ontology (GO) - Biological Process for IQCC Gene

None

No data available for Pathways by source for IQCC Gene

Transcripts for IQCC Gene

mRNA/cDNA for IQCC Gene

Unigene Clusters for IQCC Gene

IQ motif containing C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for IQCC

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for IQCC
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCC Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5
SP1: - - -
SP2: - -
SP3: -
SP4: -

Relevant External Links for IQCC Gene

GeneLoc Exon Structure for
IQCC
ECgene alternative splicing isoforms for
IQCC

Expression for IQCC Gene

mRNA expression in normal human tissues for IQCC Gene

mRNA differential expression in normal tissues according to GTEx for IQCC Gene

This gene is overexpressed in Testis (4.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for IQCC Gene

SOURCE GeneReport for Unigene cluster for IQCC Gene Hs.274356

genes like me logo Genes that share expressions with IQCC: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCC Gene

Orthologs for IQCC Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IQCC 35
  • 99.45 (n)
  • 98.9 (a)
IQCC 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia IQCC 35
  • 75.91 (n)
  • 56.68 (a)
IQCC 36
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia IQCC 35
  • 74.44 (n)
  • 54.06 (a)
IQCC 36
  • 56 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Iqcc 35
  • 72.28 (n)
  • 56.19 (a)
Iqcc 16
Iqcc 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Iqcc 35
  • 68.43 (n)
  • 52.16 (a)
lizard
(Anolis carolinensis)
Reptilia IQCC 36
  • 35 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii iqcc 36
  • 22 (a)
OneToOne
Species with no ortholog for IQCC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCC Gene

ENSEMBL:
Gene Tree for IQCC (if available)
TreeFam:
Gene Tree for IQCC (if available)

Paralogs for IQCC Gene

No data available for Paralogs for IQCC Gene

Variants for IQCC Gene

Sequence variations from dbSNP and Humsavar for IQCC Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs34444395 -- 32,206,862(+) CCTTT(-/T)CCCGT intron-variant
rs41311187 -- 32,206,588(+) CCCAT(A/G)TGAAG missense, reference
rs76174970 -- 32,206,357(+) CCCTT(A/C)CCAGT intron-variant
rs78002993 -- 32,206,356(+) ACCCT(A/T)CCCAG intron-variant
rs111262685 -- 32,206,865(+) TTTCC(C/T)GTCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IQCC Gene

Variant ID Type Subtype PubMed ID
nsv300 CNV Insertion 18451855

Relevant External Links for IQCC Gene

HapMap Linkage Disequilibrium report
IQCC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCC Gene

Disorders for IQCC Gene

No disorders were found for IQCC Gene.

No data available for UniProtKB/Swiss-Prot for IQCC Gene

Publications for IQCC Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for IQCC Gene

Sources for IQCC Gene

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