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Aliases for IQCC Gene

Aliases for IQCC Gene

  • IQ Motif Containing C 2 3 5

External Ids for IQCC Gene

Previous GeneCards Identifiers for IQCC Gene

  • GC01P032340
  • GC01P032443
  • GC01P032671
  • GC01P030787

Summaries for IQCC Gene

GeneCards Summary for IQCC Gene

IQCC (IQ Motif Containing C) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IQCC Gene

Genomics for IQCC Gene

Regulatory Elements for IQCC Gene

Enhancers for IQCC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around IQCC on UCSC Golden Path with GeneCards custom track

Promoters for IQCC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around IQCC on UCSC Golden Path with GeneCards custom track

Genomic Location for IQCC Gene

32,205,635 bp from pter
32,208,687 bp from pter
3,053 bases
Plus strand

Genomic View for IQCC Gene

Genes around IQCC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IQCC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IQCC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IQCC Gene

Proteins for IQCC Gene

  • Protein details for IQCC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    IQ domain-containing protein C
    Protein Accession:
    Secondary Accessions:
    • F5H7T8
    • Q4KMS3
    • Q4KMZ5
    • Q53FL2
    • Q5TFJ8
    • Q9NVS3

    Protein attributes for IQCC Gene

    466 amino acids
    Molecular mass:
    53032 Da
    Quaternary structure:
    No Data Available
    • Sequence=AK307853; Type=Erroneous termination; Positions=323; Note=Translated as Gln.; Evidence={ECO:0000305};

    Alternative splice isoforms for IQCC Gene


neXtProt entry for IQCC Gene

Post-translational modifications for IQCC Gene

  • Ubiquitination at Lys 127
  • Modification sites at PhosphoSitePlus

Other Protein References for IQCC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for IQCC Gene

Domains & Families for IQCC Gene

Protein Domains for IQCC Gene


Suggested Antigen Peptide Sequences for IQCC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 IQ domain.
  • Contains 1 IQ domain.
genes like me logo Genes that share domains with IQCC: view

No data available for Gene Families for IQCC Gene

Function for IQCC Gene

genes like me logo Genes that share phenotypes with IQCC: view

Animal Model Products

CRISPR Products

miRNA for IQCC Gene

miRTarBase miRNAs that target IQCC

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IQCC Gene

Localization for IQCC Gene

Subcellular locations from

Jensen Localization Image for IQCC Gene COMPARTMENTS Subcellular localization image for IQCC gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IQCC Gene

Pathways & Interactions for IQCC Gene

SuperPathways for IQCC Gene

No Data Available

Interacting Proteins for IQCC Gene

Gene Ontology (GO) - Biological Process for IQCC Gene


No data available for Pathways by source and SIGNOR curated interactions for IQCC Gene

Drugs & Compounds for IQCC Gene

No Compound Related Data Available

Transcripts for IQCC Gene

mRNA/cDNA for IQCC Gene

Unigene Clusters for IQCC Gene

IQ motif containing C:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IQCC Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5
SP1: - - -
SP2: - -
SP3: -
SP4: -

Relevant External Links for IQCC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IQCC Gene

mRNA expression in normal human tissues for IQCC Gene

mRNA differential expression in normal tissues according to GTEx for IQCC Gene

This gene is overexpressed in Testis (x4.0).

Protein differential expression in normal tissues from HIPED for IQCC Gene

This gene is overexpressed in Breast (54.1) and Lung (13.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IQCC Gene

Protein tissue co-expression partners for IQCC Gene

NURSA nuclear receptor signaling pathways regulating expression of IQCC Gene:


SOURCE GeneReport for Unigene cluster for IQCC Gene:

genes like me logo Genes that share expression patterns with IQCC: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IQCC Gene

Orthologs for IQCC Gene

This gene was present in the common ancestor of chordates.

Orthologs for IQCC Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia IQCC 34
  • 75.91 (n)
  • 56.68 (a)
  • 60 (a)
(Canis familiaris)
Mammalia IQCC 34
  • 74.44 (n)
  • 54.06 (a)
  • 56 (a)
(Mus musculus)
Mammalia Iqcc 34
  • 72.28 (n)
  • 56.19 (a)
Iqcc 16
Iqcc 35
  • 55 (a)
(Pan troglodytes)
Mammalia IQCC 34
  • 99.45 (n)
  • 98.9 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Iqcc 34
  • 68.43 (n)
  • 52.16 (a)
(Anolis carolinensis)
Reptilia IQCC 35
  • 35 (a)
(Danio rerio)
Actinopterygii iqcc 35
  • 22 (a)
Species where no ortholog for IQCC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IQCC Gene

Gene Tree for IQCC (if available)
Gene Tree for IQCC (if available)

Paralogs for IQCC Gene

No data available for Paralogs for IQCC Gene

Variants for IQCC Gene

Sequence variations from dbSNP and Humsavar for IQCC Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_031411 -
VAR_031412 -
VAR_031413 -

Structural Variations from Database of Genomic Variants (DGV) for IQCC Gene

Variant ID Type Subtype PubMed ID
nsv300 CNV insertion 18451855

Variation tolerance for IQCC Gene

Residual Variation Intolerance Score: 80.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.58; 78.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for IQCC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IQCC Gene

Disorders for IQCC Gene

Relevant External Links for IQCC

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IQCC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IQCC Gene

Publications for IQCC Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65

Products for IQCC Gene

Sources for IQCC Gene