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Aliases for IPW Gene

Subcategory (RNA class) for IPW Gene


Quality Score for this RNA gene is


Aliases for IPW Gene

  • Imprinted In Prader-Willi Syndrome (Non-Protein Coding) 2 3
  • Non-Protein Coding RNA 2 2 3
  • NCRNA00002 3

External Ids for IPW Gene

Previous GeneCards Identifiers for IPW Gene

  • GC15U990031
  • GC15P022909
  • GC15P022912
  • GC15P025361
  • GC15P003497

Summaries for IPW Gene

Entrez Gene Summary for IPW Gene

  • This gene is non-protein coding, is expressed exclusively from the paternal allele, and may play a role in the imprinting process. Mutations in this gene are associated with Prader-Willi syndrome. [provided by RefSeq, May 2010]

GeneCards Summary for IPW Gene

IPW (Imprinted In Prader-Willi Syndrome (Non-Protein Coding)) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with IPW include prader-willi syndrome.

fRNAdb sequence ontologies for IPW Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • mature_transcript: A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified.

  • ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for IPW Gene

Genomics for IPW Gene

Genomic Location for IPW Gene

25,116,545 bp from pter
25,122,476 bp from pter
5,932 bases
Plus strand

Genomic View for IPW Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IPW Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IPW Gene

Proteins for IPW Gene

Post-translational modifications for IPW Gene

No Post-translational modifications

No data available for DME Specific Peptides for IPW Gene

Domains for IPW Gene

Gene Families for IPW Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IPW: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IPW Gene

Function for IPW Gene

Molecular function for IPW Gene

GENATLAS Biochemistry:
paternally expressed gene,imprinted in Prader-Willi region,may be the same as Par-1 or 7 (see PWCR)

Phenotypes for IPW Gene

GenomeRNAi human phenotypes for IPW:
genes like me logo Genes that share phenotypes with IPW: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IPW Gene

Localization for IPW Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IPW Gene

Pathways for IPW Gene

SuperPathways for IPW Gene

No Data Available

Interacting Proteins for IPW Gene

Gene Ontology (GO) - Biological Process for IPW Gene


No data available for Pathways by source for IPW Gene

Transcripts for IPW Gene

mRNA/cDNA for IPW Gene

(1) Selected AceView cDNA sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for IPW Gene

No ASD Table

Relevant External Links for IPW Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IPW Gene

mRNA expression in normal human tissues for IPW Gene

genes like me logo Genes that share expressions with IPW: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for IPW Gene

Orthologs for IPW Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for IPW Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Ipw 16
Species with no ortholog for IPW:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for IPW Gene

Paralogs for IPW Gene

No data available for Paralogs for IPW Gene

Variants for IPW Gene

Sequence variations from dbSNP and Humsavar for IPW Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs691 -- 25,119,648(+) CAAAT(C/T)ACCTC nc-transcript-variant
rs13526 -- 25,119,883(+) CTTAT(A/C)AGTTG nc-transcript-variant
rs16416 -- 25,120,023(+) GCCTC(-/ACAG)ACAAT nc-transcript-variant
rs1043164 -- 25,119,404(+) CCACA(C/T)GGTAA nc-transcript-variant
rs2356293 -- 25,117,693(-) GACCT(C/G)TTGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for IPW Gene

Variant ID Type Subtype PubMed ID
nsv903721 CNV Gain 21882294

Relevant External Links for IPW Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IPW Gene

Disorders for IPW Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for IPW Gene in MalaCards »

(1) Disease for IPW Gene

(1) Novoseek inferred disease relationships for IPW Gene

Disease -log(P) Hits PubMed IDs
prader-willi syndrome 86.3 4
genes like me logo Genes that share disorders with IPW: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Genatlas and External Links for IPW Gene

Publications for IPW Gene

  1. Imprinted genes in the Prader-Willi deletion. (PMID: 9601023) Francke U. (Novartis Found. Symp. 1998) 2 3 23
  2. Identification of a novel paternally expressed gene in the Prader-Willi syndrome region. (PMID: 7849716) Wevrick R. … Francke U. (Hum. Mol. Genet. 1994) 2 3
  3. Clonal maintenance of imprinted expression of SNRPN and IPW in normal lymphocytes: correlation with allele-specific methylation of SNRPN intron 1 but not intron 7. (PMID: 11281449) Balmer D. … LaSalle J.M. (Hum. Genet. 2001) 23
  4. Analysis of imprinted genes in subjects with Prader-Willi syndrome and chromosome 15 abnormalities. (PMID: 11258349) Muralidhar B. … Butler M.G. (Genet. Med. 1999) 23
  5. Association of acetylated histones with paternally expressed genes in the Prader--Willi deletion region. (PMID: 11230184) Fulmer-Smentek S.B. … Francke U. (Hum. Mol. Genet. 2001) 23

Products for IPW Gene

Sources for IPW Gene

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