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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IPPK Gene

protein-coding   GIFtS: 49
GCID: GC09M095375

inositol 1,3,4,5,6-pentakisphosphate 2-kinase

(Previous name: chromosome 9 open reading frame 12 )
(Previous symbol: C9orf12)
 Explore 1 disease affiliated with
IPPK via our new
 Human Malady Compendium 
Biological research products
for IPPK
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase1 2     EC 2.7.1.1583 8
C9orf121 2 3     FLJ131631
INSP5K21 2     Chromosome 9 Open Reading Frame 121
IP5K1 2     BA476B13.11
IPK11 2     BA476B13.1 (Novel Protein)2
Ins(1,3,4,5,6)P5 2-Kinase2 3     Inositol-Pentakisphosphate 2-Kinase2
InsP5 2-Kinase2 3     Inositol-1,3,4,5,6-Pentakisphosphate 2-Kinase3
IPK1 Homolog2 3     

External Ids:    HGNC: 146451   Entrez Gene: 647682   Ensembl: ENSG000001270807   UniProtKB: Q9H8X23   

Export aliases for IPPK gene to outside databases

Previous GC identifers: GC09M092457 GC09M094415 GC09M065053


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IPPK:
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to
form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA
repair, endocytosis, and mRNA export. (provided by RefSeq, Nov 2010)

UniProtKB/Swiss-Prot: IPPK_HUMAN, Q9H8X2
Function: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is
involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It
also protects cells from TNF-alpha-induced apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IPPK gene promoter:
         GATA-3   XBP-1   Nkx2-5   NF-E2 p45   GATA-1   GATA-2   FOXO1a   NF-E2   Hlf   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIPPK promoter sequence
   Search SABiosciences Chromatin IP Primers for IPPK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IPPK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.31

IPPK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IPPK gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M095375:  view genomic region     (about GC identifiers)

Start:
95,375,466 bp from pter      End:
95,432,547 bp from pter
Size:
57,082 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IPPK_HUMAN, Q9H8X2 (See protein sequence)
Recommended Name: Inositol-pentakisphosphate 2-kinase  
Size: 491 amino acids; 56017 Da
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Sequence caution: Sequence=BAB14866.1; Type=Erroneous initiation; Sequence=CAI12593.1; Type=Erroneous gene model
prediction;
Secondary accessions: Q5T9F7 Q9H7V8

Explore the universe of human proteins at neXtProt for IPPK: NX_Q9H8X2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H8X2

  • 2 DME Specific Peptides for IPPK (Q9H8X2)
     LQIDGPYDE  TAKDCSIMI 

    IPPK Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_073592.1  
    ENSEMBL proteins: 
     ENSP00000287996   ENSP00000364672  
    Reactome Protein details: Q9H8X2
    Human Recombinant Protein Products: 
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    Novus Biologicals IPPK Proteins
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    Uscn Proteins for IPPK

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA12084730
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--


    IPPK for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    IPPK for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009286 Ins_P5_2-kin

    Graphical View of Domain Structure for InterPro Entry Q9H8X2

    ProtoNet protein and cluster: Q9H8X2

    UniProtKB/Swiss-Prot: IPPK_HUMAN, Q9H8X2
    Domain: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2
    Similarity: Belongs to the IPK1 type 2 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: IPPK_HUMAN, Q9H8X2
    Function: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is
    involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It
    also protects cells from TNF-alpha-induced apoptosis
    Catalytic activity: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate
    Biophysicochemical properties: Kinetic parameters: KM=0.43 uM for Ins(1,3,4,5,6)P5; KM=21 uM for ATP; Vmax=31
    nmol/min/mg enzyme;

    Enzyme Number (IUBMB): EC 2.7.1.1581 2

    miRNA
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    hsa-miR-140-5p hsa-miR-520f hsa-miR-376b hsa-miR-15a hsa-miR-199a-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-1258
    SwitchGear 3'UTR luciferase reporter plasmidIPPK 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
    GO:0035299inositol pentakisphosphate 2-kinase activity IDA12084730


    IPPK for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ippk):
     mortality/aging 

    IPPK for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1inositol pyrophosphates biosynthesis
    inositol pyrophosphates biosynthesis1.00
    Synthesis of pyrophosphates in the cytosol0.42
    Synthesis of IPs in the nucleus0.57
    2Inositol phosphate metabolism
    Inositol phosphate metabolism1.00
    Phosphatidylinositol signaling system0.59
    superpathway of inositol phosphate compounds0.59
    3Metabolism
    Metabolism1.00
    Metabolic pathways0.38
    4D-myo-inositol (1,3,4)-trisphosphate biosynthesis
    1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)0.76
    5D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis
    1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)0.67

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4 BioSystems Pathways for IPPK 
        inositol pyrophosphates biosynthesis
    1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
    1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
    superpathway of inositol phosphate compounds

    4        Reactome Pathways for IPPK
        Synthesis of IPs in the nucleus
    Metabolism
    Synthesis of pyrophosphates in the cytosol
    Inositol phosphate metabolism


    3         Kegg Pathways  (Kegg details for IPPK):
        Inositol phosphate metabolism
    Metabolic pathways
    Phosphatidylinositol signaling system


    IPPK for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IPPK

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for IPPK (ENSP000002879964) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IP6K2ENSP000003311034STRING: ENSP00000331103
    IPMKENSP000003630464STRING: ENSP00000363046
    ITPK1ENSP000002676154STRING: ENSP00000267615
    IP6K1ENSP000003237804STRING: ENSP00000323780
    IP6K3ENSP000002937564STRING: ENSP00000293756
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0052746inositol phosphorylation IDA12084730


    IPPK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for IPPK

    4 HMDB Compounds for IPPK    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Inositol 1,3,4,5,6-pentakisphosphate1D-myo-Inositol 1,3,4,5,6-pentakisphosphate (see all 5)20298-95-7--
    Myo-inositol hexakisphosphate1D-myo-Inositol 1,2,3,4,5,6-hexakisphosphate (see all 9)83-86-3--
    Search CenterWatch for drugs/clinical trials and news about IPPK 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IPPK gene: 
    NM_022755.5  

    Unigene Cluster for IPPK:

    Inositol 1,3,4,5,6-pentakisphosphate 2-kinase
    Hs.459896  [show with all ESTs]
    Unigene Representative Sequence: NM_022755
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000287996(uc004ask.1 uc004asl.1) ENST00000486841 ENST00000375522


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    hsa-miR-140-5p hsa-miR-520f hsa-miR-376b hsa-miR-15a hsa-miR-199a-3p hsa-miR-1224-3p hsa-miR-1260b hsa-miR-1258
    SwitchGear 3'UTR luciferase reporter plasmidIPPK 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AF351200.1 AF351202.1 AF520811.1 AK023225.1 AK024267.1 BC026154.2 

    12 DOTS entries:

    DT.99976581  DT.99977485  DT.95372754  DT.213558  DT.121154288  DT.100747010  DT.95120509  DT.121154194 
    DT.408172  DT.100714130  DT.101960109  DT.95372757 

    24/95 AceView cDNA sequences (see all 95):

    AI935135 NM_022755 BM718532 AI079557 CF122254 BQ220575 AA766264 AK096392 
    BI850493 AF351202 BG682005 AI087226 CO403300 AW009360 BC026154 AF520811 
    AI922155 AU131742 AA336588 AK023225 AI963115 AF351200 BM476798 BM794579 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for IPPK    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c
    SP1:                                                                    -                 -                                 
    SP2:                                                                    -     -           -                                 
    SP3:                                                                                                                        
    SP4:                                                                                                                        


    ECgene alternative splicing isoforms for IPPK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IPPK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See IPPK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IPPK

    SOURCE GeneReport for Unigene cluster: Hs.459896

    UniProtKB/Swiss-Prot: IPPK_HUMAN, Q9H8X2
    Tissue specificity: Ubiquitously expressed, with high expression in heart, brain, testis and placenta

        SABiosciences Custom PCR Arrays for IPPK
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IPPK gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ippk1 , 5 inositol 1,3,4,5,6-pentakisphosphate 2-kinase1, 5 87.8(n)1
    91.41(a)1
      13 (25.25 cM)5
    756781  NM_199056.21  NP_951011.11 
     494213115 
    chicken
    (Gallus gallus)
    Aves IPPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase 74.88(n)
    79.84(a)
      415951  XM_414295.2  XP_414295.1 
    lizard
    (Anolis carolinensis)
    Reptilia IPPK6
    --
    76(a)
    1 ↔ 1
    2(156016122-156059081)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.97672 Transcribed sequence with moderate similarity to protein more 75.85(n)    BX692344.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ippk1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase 61.66(n)
    56.78(a)
      541511  NM_001014324.1  NP_001014346.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ipk16
    Ipk1
    17(a)
    1 ↔ 1
    2R(16758296-16766632)
    worm
    (Caenorhabditis elegans)
    Secernentea Y17G7B.136
    Protein Y17G7B.13
    21(a)
    1 ↔ 1
    II(12042846-12048981)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons IPK11 inositol-pentakisphosphate 2-kinase 45.69(n)
    37.64(a)
      834292  NM_123646.3  NP_568613.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g06612001 hypothetical protein 48.5(n)
    34.6(a)
      4337286  NM_001060682.1  NP_001054147.1 


    ENSEMBL Gene Tree for IPPK (if available)
    TreeFam Gene Tree for IPPK (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IPPK gene

    IPPK for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for IPPK
    PGOHUM00000248321


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/849 NCBI SNPs in IPPK are shown (see all 849    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs413015311,2
    C,F,--65053483(+) CAGCCG/ATAGGT 1 -- ds50012Minor allele frequency- A:0.04WA NA 238
    rs796589751,2
    C,--65054062(+) GATGTG/TTGGGG 1 -- ut312Minor allele frequency- T:0.09WA 120
    rs413054891,2
    F,--65054067(+) GTGGGG/AAGGAT 1 -- ut311Minor allele frequency- A:0.04WA 118
    rs1140879031,2
    C,F,--65054101(+) CACACC/TGAGTC 1 -- ut311Minor allele frequency- T:0.03WA 118
    rs169084741,2
    C,F,H,--65054329(+) TCCACA/GAGAAA 1 -- ut31 ese319Minor allele frequency- G:0.04NA NS EA WA 1782
    rs70209851,2
    C,--65054718(+) CAAATA/GCAGGC 1 -- ut31 ese32Minor allele frequency- G:0.06CSA NA 122
    rs70245361,2
    C,F,A,H,--65054947(+) TCCCTT/CGGGTC 1 -- ut31 ese315Minor allele frequency- C:0.06NS EA NA WA CSA 1794
    rs727544961,2
    C,F,--65054988(+) GCTTCC/ACAGAG 1 -- ut312Minor allele frequency- A:0.03NA EA 240
    rs38023821,2
    C,H,--65055405(+) TGAAAC/GCAAGA 1 -- ut31 ese36Minor allele frequency- G:0.00NS EA NA 422
    rs38023831,2
    C,F,H,--65055458(+) CCAACG/AAGAAC 1 -- ut31 ese313Minor allele frequency- A:0.03EA NS NA 2544

    HapMap Linkage Disequilibrium report for IPPK (95375466 - 95432547 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for IPPK: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IPPK
    DNA2.0 Custom Variant and Variant Library Synthesis for IPPK

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    IPPK for disorders           About GeneDecksing

    1 disease for IPPK:    About MalaCards
    tetralogy of fallot

    2 diseases from the University of Copenhagen DISEASES database for IPPK:
    Tetralogy of Fallot     Atrial heart septal defect

    Export disorders for IPPK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IPPK gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with IPPK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. (PubMed id 12084730)1, 2, 3, 9 Verbsky J.W.... Wente S.R. (2002)
    2. Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis. (PubMed id 15967797)1, 2, 9 Verbsky J. and Majerus P.W. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)
    9. Physiological levels of PTEN control the size of the cellular Ins(1,3,4,5,6)P(5) pool. (PubMed id 15979280)1 Deleu S....Shears S.B. (2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64768 HGNC: 14645 AceView: C9orf12 Ensembl:ENSG00000127080 euGenes: HUgn64768
    ECgene: IPPK Kegg: 64768 H-InvDB: IPPK

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IPPK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IPPK gene:
    Search GeneIP for patents involving IPPK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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