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IPP Gene

protein-coding   GIFtS: 50
GCID: GC01M046159

Intracisternal A Particle-Promoted Polypeptide

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Intracisternal A Particle-Promoted Polypeptide1 2 3
Kelch-Like Family Member 271 2
Kelch-Like Protein 272 3
KLHL272 3
Actin-Binding Protein IPP2

External Ids:    HGNC: 61081   Entrez Gene: 36522   Ensembl: ENSG000001974297   OMIM: 1474855   UniProtKB: Q9Y5733   

Export aliases for IPP gene to outside databases

Previous GC identifers: GC01M045891 GC01M045164 GC01M045594 GC01M045577 GC01M045829 GC01M044271


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IPP Gene:
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino
acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has
not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for IPP Gene:
IPP (intracisternal A particle-promoted polypeptide) is a protein-coding gene. Diseases associated with IPP include peroneal nerve paralysis, and placenta praevia. GO annotations related to this gene include actin binding. An important paralog of this gene is GAN.

UniProtKB/Swiss-Prot: IPP_HUMAN, Q9Y573
Function: May play a role in organizing the actin cytoskeleton




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the IPP gene promoter:
         ER-alpha   AML1a   AP-1   POU3F1   SREBP-1c   ATF-2   SREBP-1b   FOXC1   SREBP-1a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIPP promoter sequence
   Search Chromatin IP Primers for IPP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IPP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34-p32   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34-p32

IPP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IPP gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M046159:  view genomic region     (about GC identifiers)

Start:
46,159,996 bp from pter      End:
46,216,485 bp from pter
Size:
56,490 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IPP_HUMAN, Q9Y573 (See protein sequence)
Recommended Name: Actin-binding protein IPP  
Size: 584 amino acids; 65261 Da
Secondary accessions: A2A6V4 D3DQ11 Q8N5C3
Alternative splicing: 2 isoforms:  Q9Y573-1   Q9Y573-2   

Explore the universe of human proteins at neXtProt for IPP: NX_Q9Y573

Explore proteomics data for IPP at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys238, Lys279
  • Modification sites at PhosphoSitePlus

  • See IPP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138821.1  NP_005888.1  

    ENSEMBL proteins: 
     ENSP00000353024   ENSP00000379739  

    IPP Human Recombinant Protein Products:

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    Cloud-Clone Corp. ELISAs for IPP
    Cloud-Clone Corp. CLIAs for IPP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    KLHL: Kelch-like

    Selected InterPro protein domains (see all 8):
     IPR011043 Gal_Oxase/kelch_b-propeller
     IPR017096 Kelch-like_gigaxonin-typ
     IPR000210 BTB/POZ-like
     IPR006652 Kelch_1
     IPR011333 BTB/POZ_fold

    Graphical View of Domain Structure for InterPro Entry Q9Y573

    ProtoNet protein and cluster: Q9Y573

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated


    UniProtKB/Swiss-Prot: IPP_HUMAN, Q9Y573
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 6 Kelch repeats


    IPP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IPP_HUMAN, Q9Y573
    Function: May play a role in organizing the actin cytoskeleton

         Genatlas biochemistry entry for IPP:
    intracisternal A-particle (IAP)-promoted,placenta,mouse homolog,Kelch family member

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005515protein binding ----
         
    IPP for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IPP:
     Increased cell death HMECs cel 

         1 MGI phenotypic allele for Ipp (no phenotypes)

    IPP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ipptm1(KOMP)Vlcg for IPP

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IPP
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IPP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IPP

    miRNA
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    miRTarBase miRNAs that target IPP:
    hsa-mir-21-5p (MIRT030826), hsa-mir-222-3p (MIRT046572)

    Block miRNA regulation of human, mouse, rat IPP using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate IPP:
    hsa-miR-548p hsa-miR-607 hsa-miR-3688-3p hsa-miR-1305 hsa-miR-548g hsa-miR-518a-5p hsa-miR-450b-5p hsa-miR-192*
    SwitchGear 3'UTR luciferase reporter plasmidIPP 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat IPP

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    GenScript: all cDNA clones in your preferred vector (see all 2): IPP (NM_001145349)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IPP

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IPP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IPP_HUMAN, Q9Y573: Cytoplasm, cytoskeleton
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    chloroplast2
    nucleus2
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0015629actin cytoskeleton TAS10072760

    IPP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IPP
    Interactions:

        Search GeneGlobe Interaction Network for IPP

    1 Interacting protein for IPP (Q9Y5733) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALCOCO1Q9P1Z23I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IPP



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IPP gene (2 alternative transcripts): 
    NM_001145349.1  NM_005897.2  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359942(uc001cos.4) ENST00000461718 ENST00000495072 ENST00000396478(uc001cou.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IPP using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate IPP:
    hsa-miR-548p hsa-miR-607 hsa-miR-3688-3p hsa-miR-1305 hsa-miR-548g hsa-miR-518a-5p hsa-miR-450b-5p hsa-miR-192*
    SwitchGear 3'UTR luciferase reporter plasmidIPP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IPP
    Predesigned siRNA for gene silencing in human, mouse, rat IPP
    Clone
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    OriGene clones in human, mouse for IPP (see all 12)
    OriGene ORF clones in mouse, rat for IPP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): IPP (NM_001145349)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IPP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IPP
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IPP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IPP
      QuantiTect SYBR Green Assays in human, mouse, rat IPP
      QuantiFast Probe-based Assays in human, mouse, rat IPP

    18 AceView cDNA sequences:

    BM468310 BM832170 BQ788131 AU141321 BM833305 BM754282 AA346876 BQ777465 
    BE545147 BX472610 BM509814 BI766417 BF934855 BC032544 AK023880 AF156857 
    NM_005897 CB992320 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IPP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAACCTGTC
    IPP Expression
    About this image

    IPP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IPP Protein Expression
        Custom PCR Arrays for IPP
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IPP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IPP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IPP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for IPP gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ipp1 , 5 IAP promoted placental gene1, 5 89.5(n)1
    93.49(a)1
      4 (53.20 cM)5
    163511  NM_008389.31  NP_032415.21 
     1165075525 
    chicken
    (Gallus gallus)
    Aves IPP1 intracisternal A particle-promoted polypeptide 75.59(n)
    83.36(a)
      424605  XM_004936756.1  XP_004936813.1 
    lizard
    (Anolis carolinensis)
    Reptilia IPP6
    intracisternal A particle-promoted polypeptide
    76(a)
    1 ↔ 1
    4(111112425-111119965)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX843532.12   -- 77.86(n)    BX843532.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ipp1 intracisternal A particle-promoted polypeptide 67.69(n)
    71.58(a)
      570768  NM_001113621.1  NP_001107093.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94261 , 3 actin binding3
    CG94261
    37(a)3
    48.4(n)1
    38.52(a)1
      34A103
    347191  NM_135772.21  NP_609616.11 


    ENSEMBL Gene Tree for IPP (if available)
    TreeFam Gene Tree for IPP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IPP gene
    GAN2  KLHDC8B2  KLHL72  IVNS1ABP2  KLHDC8A2  
    16 SIMAP similar genes for IPP using alignment to 1 protein entry:     IPP_HUMAN:
    KLHL12    KLHL4    KLHL5    KLHL1    KEAP1    KLHL17
    KLHL20    KLHL28    KLHL3    KLHL2    DKFZp686P15123    KLHL18
    KLHL8    DKFZp686H07112    KLHL10    KLHL7

    IPP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IPP (see all 1159)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1447057371,2
    C--46160609(+) CTGGAA/GTGCAG 1 -- int10--------
    rs1479144071,2
    C--46160635(+) TCACCA/GCAACC 1 -- int10--------
    rs1930687791,2
    --46160642(+) AACCTC/GCACCT 1 -- int10--------
    rs1849693121,2
    --46160650(+) CCTCCC/TGAGTT 1 -- int10--------
    rs1866768501,2
    --46160660(+) TCAAGC/TGATTC 1 -- int10--------
    rs1417478801,2
    --46160691(+) AGTAGC/GTGGGA 1 -- int10--------
    rs1914389261,2
    --46160781(+) GGCTGA/GTCTAG 1 -- int10--------
    rs1388768351,2
    C--46160829(+) TGGTG-/TGTTTT
            
    TGTTT
    1 -- int10--------
    rs2020938781,2
    C--46160838(+) TTTGT-/TTTTG 
            
    TTTTG
    1 -- int10--------
    rs2012595431,2
    C--46160842(+) TTTTT-/TTTTGT 1 -- int10--------

    HapMap Linkage Disequilibrium report for IPP (46159996 - 46216485 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IPP (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1730955CNV Deletion17803354
    esv2023284CNV Deletion18987734
    esv4646CNV Deletion18987735
    esv2747830CNV Deletion23290073
    esv1007960CNV Insertion20482838
    nsv436781CNV Insertion17901297
    dgv219n71CNV Loss21882294
    nsv871763CNV Loss21882294
    nsv159558CNV Loss16902084
    nsv871233CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IPP
    DNA2.0 Custom Variant and Variant Library Synthesis for IPP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 147485    OMIM disorders: --

    9 diseases for IPP:    
    About MalaCards
    peroneal nerve paralysis    placenta praevia    cardiac tamponade    peyronie's disease
    peyronies disease    impotence    gastroesophageal reflux disease    precocious puberty
    malaria

    2 diseases from the University of Copenhagen DISEASES database for IPP:
    Peyronie's disease     Cardiac tamponade

    IPP for disorders           About GeneDecksing


    Export disorders for IPP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IPP gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with IPP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The IPP gene is assigned to human chromosome 1p32-1p22. (PubMed id 8432546)1, 2, 3 Chang-Yeh A.... Huang R.C. (Genomics 1993)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Isolation and characterization of IPP, a novel human gene encoding an actin-binding, kelch-like protein. (PubMed id 10072760)1, 2 Kim I.F.... Huang R.C. (Gene 1999)
    4. Cell lineage-specific expression of the MIPP gene. (PubMed id 1905535)1, 3 Mold D.E....Huang R.C. (Biochem. Biophys. Res. Commun. 1991)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Update on the Kelch-like (KLHL) gene family. (PubMed id 23676014)1 Dhanoa B.S....Friedman J.S. (Hum. Genomics 2013)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3652 HGNC: 6108 AceView: IPP Ensembl:ENSG00000197429 euGenes: HUgn3652
    ECgene: IPP H-InvDB: IPP

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IPP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IPP gene:
    Search GeneIP for patents involving IPP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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