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IPO9 Gene

protein-coding   GIFtS: 53
GCID: GC01P201798

Importin 9

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Importin 91 2     IMP93
Ran-Binding Protein 92 3     KIAA11923
Imp92 3     RANBP93
importin-92     RanBP93
ranBP92     

External Ids:    HGNC: 194251   Entrez Gene: 557052   Ensembl: ENSG000001987007   UniProtKB: Q96P703   

Export aliases for IPO9 gene to outside databases

Previous GC identifers: GC01P197232 GC01P198264 GC01P199086 GC01P198529 GC01P200064 GC01P172964


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IPO9 Gene:
IPO9 (importin 9) is a protein-coding gene. Diseases associated with IPO9 include liposarcoma, and cystic fibrosis. GO annotations related to this gene include protein transporter activity and Ran GTPase binding.

UniProtKB/Swiss-Prot: IPO9_HUMAN, Q96P70
Function: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear
localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex
to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated
through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds
to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the
cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by
an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By
similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the
cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4
histones (By similarity), RPL4 and RPL6

Gene Wiki entry for IPO9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IPO9 gene promoter:
         HOXA9B   HOXA9   NRSF form 1   CUTL1   NRSF form 2   MZF-1   STAT3   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIPO9 promoter sequence
   Search Chromatin IP Primers for IPO9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IPO9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q31.3

IPO9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IPO9 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P201798:  view genomic region     (about GC identifiers)

Start:
201,798,269 bp from pter      End:
201,853,422 bp from pter
Size:
55,154 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IPO9_HUMAN, Q96P70 (See protein sequence)
Recommended Name: Importin-9  
Size: 1041 amino acids; 115963 Da
Subunit: Binds with high affinity to RPS7 and RPL18A. The binding is coupled to RanGTP cycles. May bind H2A, H3,
H4 histones (By similarity), RPL4 and RPL6 with low affinity. Interacts with PPP2R1A and PPP2R1B
Sequence caution: Sequence=AAF28951.1; Type=Frameshift; Positions=982; Sequence=BAA86506.1; Type=Erroneous
initiation; Sequence=BAA91588.1; Type=Erroneous initiation; Sequence=BAB55181.1; Type=Erroneous initiation;
Sequence=BAC11173.1; Type=Erroneous initiation;
Secondary accessions: B1ASV5 Q8N1Y1 Q8N3I2 Q8NCG9 Q96SU6 Q9NW01 Q9P0A8 Q9ULM8

Explore the universe of human proteins at neXtProt for IPO9: NX_Q96P70

Explore proteomics data for IPO9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys773, Lys865, Lys884
  • Modification sites at PhosphoSitePlus

  • See IPO9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060555.2  
    ENSEMBL proteins: 
     ENSP00000354742   ENSP00000387761  

    IPO9 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IPO: Importins

    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR001494 Importin-beta_N
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q96P70

    ProtoNet protein and cluster: Q96P70

    UniProtKB/Swiss-Prot: IPO9_HUMAN, Q96P70
    Similarity: Belongs to the importin beta family
    Similarity: Contains 1 importin N-terminal domain


    IPO9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IPO9_HUMAN, Q96P70
    Function: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear
    localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex
    to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated
    through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds
    to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the
    cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by
    an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By
    similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the
    cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4
    histones (By similarity), RPL4 and RPL6

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI11823430
    GO:0008536Ran GTPase binding IEA--
    GO:0008565protein transporter activity IDA11823430
    GO:0042393histone binding ISS--
         
    IPO9 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IPO9:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ipo9):
     mortality/aging 

    IPO9 for phenotypes           About GeneDecksing

    Animal Models:
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    Block miRNA regulation of human, mouse, rat IPO9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IPO9 (see all 94):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-15a hsa-miR-3074-3p hsa-miR-1304 hsa-miR-149 hsa-miR-3909 hsa-miR-3174
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IPO9

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IPO9_HUMAN, Q96P70: Cytoplasm (By similarity). Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA11823430

    IPO9 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IPO9
    Interactions:

        GeneGlobe Interaction Network for IPO9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for IPO9 (Q96P702, 3 ENSP000003547424) via UniProtKB, MINT, STRING, and/or I2D (see all 981)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006606protein import into nucleus NAS11823430
    GO:0006886intracellular protein transport ----

    IPO9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IPO9

    1 HMDB Compound for IPO9    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IPO9 gene: 
    NM_018085.4  

    Unigene Cluster for IPO9:

    Importin 9
    Hs.596014  [show with all ESTs]
    Unigene Representative Sequence: NM_018085
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361565(uc001gwz.3) ENST00000464348 ENST00000479374 ENST00000456707

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate IPO9 (see all 94):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-15a hsa-miR-3074-3p hsa-miR-1304 hsa-miR-149 hsa-miR-3909 hsa-miR-3174
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IPO9 (NM_018085)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IPO9
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for IPO9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IPO9
      QuantiTect SYBR Green Assays in human, mouse, rat IPO9
      QuantiFast Probe-based Assays in human, mouse, rat IPO9

    Additional mRNA sequence: 

    AB033018.1 AF070633.1 AF161391.1 AF410465.1 AK001264.1 AK027532.1 AK055940.1 AK074740.1 
    AK094276.1 AK124260.1 AL833476.1 AL834323.1 BC003604.1 

    17 DOTS entries:

    DT.116369  DT.91703183  DT.40258258  DT.121338794  DT.91763753  DT.97768523  DT.100874321  DT.121338874 
    DT.95278452  DT.91763759  DT.91890236  DT.121338753  DT.121338771  DT.121338884  DT.91763749  DT.95278448 
    DT.92016507 

    Selected AceView cDNA sequences (see all 352):

    CA306380 AI675403 BE278108 AI161124 BE301471 AW149119 AA333259 R58833 
    BM853584 BU625779 AW499914 BM766325 AK094276 CA489270 BU169758 BQ671177 
    BG679569 AI049515 BM989786 BE746159 AI365592 BG773879 BE217883 BE019944 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for IPO9 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a ·
    SP1:                          -                                                                                                     -                           
    SP2:                                                                                                                                                            
    SP3:                    -     -                                                                                                                                 
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19b ^ 20 ^ 21a · 21b · 21c ^ 22 ^ 23a · 23b · 23c ^ 24 ^ 25 ^ 26a · 26b
    SP1:              -                                   -                           
    SP2:                                                                              
    SP3:                                                                              
    SP4:                                                  -                           
    SP5:              -                                                               


    ECgene alternative splicing isoforms for IPO9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IPO9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IPO9 Expression
    About this image

    IPO9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IPO9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.596014
        Custom PCR Arrays for IPO9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IPO9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IPO9 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ipo91 , 5 importin 91, 5 91.68(n)1
    98.93(a)1
      1 (58.60 cM)5
    2264321  NM_153774.11  NP_722469.11 
     1353823125 
    chicken
    (Gallus gallus)
    Aves IPO91 importin 9 81.56(n)
    94.62(a)
      421167  XM_419247.4  XP_419247.3 
    lizard
    (Anolis carolinensis)
    Reptilia IPO96
    importin 9
    93(a)
    1 ↔ 1
    4(133858936-133887435)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.161702 Transcribed sequences 78.5(n)    BX728050.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc23d122 Danio rerio cDNA clone MGC66429 IMAGE2599595, complete more 78.69(n)    BC059203.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ranbp91 Ranbp9 49.18(n)
    39.06(a)
      41367  NM_141811.2  NP_650068.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes KAP114(YGL241W)4 Karyopherin, responsible for nuclear import of Spt15p, more   --   7(45445-48459) 852610  NP_011273.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G261701 AT1G26170 42.88(n)
    28.94(a)
      839158  NM_102382.2  NP_173942.2 


    ENSEMBL Gene Tree for IPO9 (if available)
    TreeFam Gene Tree for IPO9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IPO9 (see all 1273)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs577212631,2
    C--172968266(+) TTTTT-/T/TT  
            
    AATTT
    1 -- int11NA 2
    rs1424715481,2
    --201796630(+) CAGTGC/GGTGTA 1 -- us2k10--------
    rs1850921721,2
    --201796751(+) TTGAAA/GTAATC 1 -- us2k10--------
    rs1896998381,2
    --201796903(+) GCACAC/TAACCT 1 -- us2k10--------
    rs1813286351,2
    --201796967(+) AACAAC/TATTCT 1 -- us2k10--------
    rs1459267641,2
    --201797180(+) TCTGAA/GACAAG 1 -- us2k10--------
    rs1854093401,2
    --201797232(+) ACTGCC/TCACTG 1 -- us2k10--------
    rs1920025321,2
    --201797269(+) ATCTTC/GCCACC 1 -- us2k10--------
    rs1835321341,2
    --201797381(+) GTTCTC/TGAAAT 1 -- us2k10--------
    rs26441091,2
    C,F,A,H--201797535(+) CTCTGC/TACCGT 1 -- us2k112Minor allele frequency- T:0.11NS EA NA WA CSA 781

    HapMap Linkage Disequilibrium report for IPO9 (201798269 - 201853422 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for IPO9:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2667793CNV Deletion23128226
    nsv159766CNV Insertion16902084

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for IPO9:    
    About MalaCards
    liposarcoma    cystic fibrosis    malaria


    IPO9 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IPO9

    Export disorders for IPO9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IPO9 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with IPO9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. (PubMed id 11823430)1, 2, 3 Jaekel S.... Goerlich D. (EMBO J. 2002)
    2. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (DNA Res. 1999)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Interaction between protein phosphatase 2A and members of the importin beta superfamily. (PubMed id 12670497)1, 2 Lubert E.J. and Sarge K.D. (Biochem. Biophys. Res. Commun. 2003)
    6. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    7. Multiple pathways contribute to nuclear import of core histones. (PubMed id 11493596)1, 9 MA1hlhAousser P....Kutay U. (EMBO Rep. 2001)
    8. A Proteomics Strategy for the Identification of FAT10-Modified Sites by Mass Spectrometry. (PubMed id 23862649)1 Leng L....Wang J. (J. Proteome Res. 2014)
    9. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    10. Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. (PubMed id 23956138)1 Foerster S....Ritter C.A. (Proteomics 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 55705 HGNC: 19425 AceView: IPO9 Ensembl:ENSG00000198700 euGenes: HUgn55705
    ECgene: IPO9 H-InvDB: IPO9

    (According to HUGE)
    About This Section

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    HUGE: KIAA1192

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for IPO9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for IPO9 gene:
    Search GeneIP for patents involving IPO9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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