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IPCEF1 Gene

protein-coding   GIFtS: 52
GCID: GC06M154517

Interaction Protein For Cytohesin Exchange Factors 1

  Search for IPCEF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interaction Protein For Cytohesin Exchange Factors 11 2     Interaction Protein For Cytohesin Exchange Factors 1 Interaction Protein
For Cytohesin Exchange Factors 12
Phosphoinositide Binding Protein PIP3-E1 2     Interactor Protein For Cytohesin Exchange Factors 12
Phosphoinositide-Binding Protein PIP3-E2 3     KIAA04033
PIP3-E2     

External Ids:    HGNC: 212041   Entrez Gene: 260342   Ensembl: ENSG000000747067   UniProtKB: Q8WWN93   

Export aliases for IPCEF1 gene to outside databases

Previous GC identifer: GC06M152038


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IPCEF1 Gene:
IPCEF1 (interaction protein for cytohesin exchange factors 1) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and oxygen transporter activity. An important paralog of this gene is CNKSR3.

UniProtKB/Swiss-Prot: ICEF1_HUMAN, Q8WWN9
Function: Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent
manner (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IPCEF1 gene promoter:
         STAT5B   LHX3b/Lhx3b   FOXC1   LHX3a/Lhx3a   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   STAT5A   POU3F2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIPCEF1 promoter sequence
   Search Chromatin IP Primers for IPCEF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IPCEF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25.2   Ensembl cytogenetic band:  6q25.2   HGNC cytogenetic band: 6q25.2

IPCEF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IPCEF1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M154517:  view genomic region     (about GC identifiers)

Start:
154,475,618 bp from pter      End:
154,677,926 bp from pter
Size:
202,309 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ICEF1_HUMAN, Q8WWN9 (See protein sequence)
Recommended Name: Interactor protein for cytohesin exchange factors 1  
Size: 437 amino acids; 48993 Da
Subunit: Interacts with guanine-nucleotide exchange factors PSCD1, PSCD2, PSCD3 and PSCD4 (By similarity)
Caution: It is uncertain whether Met-1 or Met-29 is the initiator
Secondary accessions: A8K1K2 B7ZL78 B7ZL80 O43153 Q5HYL8
Alternative splicing: 2 isoforms:  Q8WWN9-1   Q8WWN9-2   

Explore the universe of human proteins at neXtProt for IPCEF1: NX_Q8WWN9

Explore proteomics data for IPCEF1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IPCEF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001124171.1  NP_001124172.1  NP_056368.1  

    ENSEMBL proteins: 
     ENSP00000265198   ENSP00000394751   ENSP00000356189   ENSP00000430287   ENSP00000431092  
     ENSP00000428767   ENSP00000429972   ENSP00000431004  

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    Cloud-Clone Corp. Proteins for IPCEF1

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing

    2 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q8WWN9

    ProtoNet protein and cluster: Q8WWN9

    1 Blocks protein domain: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: ICEF1_HUMAN, Q8WWN9
    Similarity: Contains 1 PH domain


    Find genes that share domains with IPCEF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ICEF1_HUMAN, Q8WWN9
    Function: Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent
    manner (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004601peroxidase activity ISS11320098
    GO:0005344oxygen transporter activity NAS11919282
         
    Find genes that share ontologies with IPCEF1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IPCEF1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IPCEF1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IPCEF1

    miRNA
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    miRTarBase miRNAs that target IPCEF1:
    hsa-mir-124-3p (MIRT022415), hsa-mir-10a-5p (MIRT047560), hsa-let-7b-5p (MIRT052329), hsa-mir-10b-5p (MIRT047416)

    Block miRNA regulation of human, mouse, rat IPCEF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IPCEF1 (see all 39):
    hsa-miR-21* hsa-miR-345 hsa-miR-3678-3p hsa-miR-4328 hsa-miR-4272 hsa-miR-3074-3p hsa-miR-628-3p hsa-miR-3923
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IPCEF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ICEF1_HUMAN, Q8WWN9: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocated with PSCD2 to
    the plasma membrane upon epidermal growth factor (EGF) stimulation (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    nucleus2
    plasma membrane2
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--

    Find genes that share ontologies with IPCEF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IPCEF1 About    
    See pathways by source

    SuperPathContained pathways About
    1Arf6 signaling events
    Arf6 signaling events


    1 BioSystems Pathway for IPCEF1
        Arf6 signaling events


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IPCEF1
    Interactions:

        Search GeneGlobe Interaction Network for IPCEF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for IPCEF1 (Q8WWN93 ENSP000003561894) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYTH2Q994183, ENSP000004082364I2D: score=3 STRING: ENSP00000408236
    CYTH1Q154383, ENSP000003543984I2D: score=1 STRING: ENSP00000354398
    CYTH3O437393, ENSP000002970444I2D: score=1 STRING: ENSP00000297044
    CYTH4Q9UIA03, ENSP000002489014I2D: score=1 STRING: ENSP00000248901
    ARF6ENSP000002983164STRING: ENSP00000298316
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006979response to oxidative stress ISS11320098
    GO:0015671oxygen transport NAS11919282
    GO:0055114oxidation-reduction process ISS11320098

    Find genes that share ontologies with IPCEF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IPCEF1 (ICEF1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IPCEF1 gene (3 alternative transcripts): 
    NM_001130699.1  NM_001130700.1  NM_015553.2  

    Unigene Cluster for IPCEF1:

    Interaction protein for cytohesin exchange factors 1
    Hs.146100  [show with all ESTs]
    Unigene Representative Sequence: NM_001130699
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470622 ENST00000265198(uc003qpv.3 uc003qpw.3 uc003qpx.3 uc010kjh.3 uc021zhc.1)
    ENST00000422970 ENST00000522590 ENST00000367220(uc021zhd.1 uc021zhe.1)
    ENST00000519344 ENST00000519091 ENST00000484827 ENST00000517438 ENST00000519405
    ENST00000519190 ENST00000518162 ENST00000520261
    miRNA
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    Block miRNA regulation of human, mouse, rat IPCEF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate IPCEF1 (see all 39):
    hsa-miR-21* hsa-miR-345 hsa-miR-3678-3p hsa-miR-4328 hsa-miR-4272 hsa-miR-3074-3p hsa-miR-628-3p hsa-miR-3923
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    GenScript: all cDNA clones in your preferred vector (see all 3): IPCEF1 (NM_001130699)
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      QuantiTect SYBR Green Assays in human, mouse, rat IPCEF1
      QuantiFast Probe-based Assays in human, mouse, rat IPCEF1

    Additional mRNA sequence: 

    AB007863.1 AJ310566.1 AK093997.1 AK289917.1 BC105015.1 BC105043.1 BC143623.1 BC143629.1 
    BX647254.1 JF308523.1 JF308524.1 

    5 DOTS entries:

    DT.95260368  DT.414270  DT.121333189  DT.99927455  DT.91961294 

    Selected AceView cDNA sequences (see all 51):

    BF436873 AX748403 BF899423 AI571473 AL596936 AK093997 AB007863 AL119039 
    BX106196 AI570712 AI619698 AL707879 BQ002283 NM_015553 Z45199 F11818 
    Z40926 D80573 BQ025505 D60144 N53325 BU580962 BU580503 AW083261 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IPCEF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCTGGAAG
    IPCEF1 Expression
    About this image


    IPCEF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Blood (Cardiovascular System)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Yolk Sac (Extraembryonic Tissues)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
    IPCEF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IPCEF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.146100
        Custom PCR Arrays for IPCEF1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IPCEF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for IPCEF1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ipcef11 , 5 interaction protein for cytohesin exchange factors more1, 5 81.89(n)1
    80.99(a)1
      10 (1.85 cM)5
    3204951  NM_001170800.11  NP_001164271.11 
     68857965 
    chicken
    (Gallus gallus)
    Aves IPCEF11 interaction protein for cytohesin exchange factors more 69.07(n)
    65.55(a)
      421645  XM_419684.4  XP_419684.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    22(a)
    1 → many
    1(215103884-215233604)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1540186
    zgc:1721126
    zgc:172112
    44(a)
    2(a)
    many ↔ many
    many ↔ many
    20(4256994-4283800) ENSDARG00000068613
    20(4178673-4254826) ENSDARG00000074236
    fruit fly
    (Drosophila melanogaster)
    Insecta cnk6
    connector enhancer of ksr
    6(a)
    1 → many
    2R(13301476-13307104)
    worm
    (Caenorhabditis elegans)
    Secernentea cnk-16
    Protein CNK-1 (cnk-1) mRNA, complete cds
    5(a)
    1 → many
    III(10271257-10278579) WBGene00000564


    ENSEMBL Gene Tree for IPCEF1 (if available)
    TreeFam Gene Tree for IPCEF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IPCEF1 gene
    CNKSR32  CNKSR12  CNKSR22  
    2 SIMAP similar genes for IPCEF1 using alignment to 6 protein entries:     ICEF1_HUMAN (see all proteins):
    CNKSR2    MYO10

    Find genes that share paralogs with IPCEF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IPCEF1 (see all 2459)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs668757921,2
    C--152132610(+) TGTGT-/GT    
       
    /GTGT
    AGAGA
    3 -- int11NA 2
    rs106082461,2
    C--152174044(+) aaaaa-/A/AA  
            
    gagag
    3 -- int11NA 2
    rs2015089561,2
    C--154568558(+) GAGATA/GAAGAA 3 -- int11Minor allele frequency- G:0.00EU 1305
    rs2001539661,2
    C--154568610(+) CTGACA/GCAAGG 6 R C mis10--------
    rs1906519571,2
    C--154568656(+) GAAATA/TTCTGA 3 -- int10--------
    rs2021096131,2
    --154568672(+) TTGTAA/GCATTT 3 -- int10--------
    rs801423971,2
    C--154568720(+) GAGCAA/GGATGG 3 -- int10--------
    rs1149551291,2
    F--154568767(+) GGAGCT/CACTAG 3 -- int11Minor allele frequency- C:0.06WA 118
    rs1134478781,2
    C,F--154568883(+) CAAGCC/TGCTCT 3 -- int11Minor allele frequency- T:0.50NA 2
    rs1826715571,2
    --154568909(+) TATGAC/TAGCAC 3 -- int10--------

    HapMap Linkage Disequilibrium report for IPCEF1 (154475618 - 154677926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for IPCEF1 (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2732939CNV Deletion23290073
    esv2665555CNV Deletion23128226
    esv2732938CNV Deletion23290073
    esv2677305CNV Deletion23128226
    nsv821323CNV Deletion20802225
    esv2510969CNV Insertion19546169
    nsv5550CNV Insertion18451855
    nsv823877CNV Loss20364138
    esv32616CNV Loss17666407
    esv1002780CNV Gain20482838

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IPCEF1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with IPCEF1           About GenesLikeMe

    Genetic Association Database (GAD): IPCEF1
    Human Genome Epidemiology (HuGE) Navigator: IPCEF1 (5 documents)

    Export disorders for IPCEF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IPCEF1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with IPCEF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. (PubMed id 11804589)1, 2, 3 Krugmann S....Hawkins P.T. (Mol. Cell 2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Peripheral nerve injury up-regulates expression of interactor protein for cytohesin exchange factor 1 (IPCEF1) mRNA in rat dorsal root ganglion. (PubMed id 19756519)1, 3 Guan X....Tao Y.X. (Naunyn Schmiedebergs Arch. Pharmacol. 2009)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2 Ishikawa K.... Ohara O. (DNA Res. 1997)
    7. CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration. (PubMed id 22085542)1 Attar M.A.... Santy L.C. (Exp. Cell Res. 2011)
    8. GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180. (PubMed id 20016009)1 White D.T....Santy L.C. (Mol. Biol. Cell 2010)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
    PubMed
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26034 HGNC: 21204 AceView: PIP3-E Ensembl:ENSG00000074706 euGenes: HUgn26034
    ECgene: IPCEF1 H-InvDB: IPCEF1

    (According to HUGE)
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    HUGE: KIAA0403

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IPCEF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IPCEF1 gene:
    Search GeneIP for patents involving IPCEF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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