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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

IP6K3 Gene

protein-coding GIFtS: 55
GCID: GC06M033689

inositol hexakisphosphate kinase 3

(Previous name: inositol hexaphosphate kinase 3 )
(Previous symbol: IHPK3)

Explore 3 diseases affiliated with
IP6K3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Inositol Hexakisphosphate Kinase 3¹ ²		InsP6 Kinase 3² ³
IHPK3¹ ² ³ ⁵		EC 2.7.4.21³ ⁸
Inositol Hexaphosphate Kinase 3¹ ² ³		ATP:1D-Myo-Inositol-Hexakisphosphate Phosphotransferase²
INSP6K3¹ ² ⁵

External Ids:	HGNC: 17269¹	Entrez Gene: 117283²	Ensembl: ENSG00000161896⁷	OMIM: 606993⁵	UniProtKB: Q96PC2³

Export aliases for IP6K3 gene to outside databases

Previous GC identifers: GC06M033798 GC06M033430

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for IP6K3:

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible

for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It

may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript

variants encoding the same protein.(provided by RefSeq, Dec 2008)

UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2

Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts

1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IP6K3 gene promoter:
Pbx1a p53 HTF FOXD1 Pax-2 Pax-2a AP-4 AREB6 Msx-1 En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IP6K3 promoter sequence

Search SABiosciences Chromatin IP Primers for IP6K3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IP6K3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31 Ensembl cytogenetic band: 6p21.31 HGNC cytogenetic band: 6p21.31

IP6K3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IP6K3 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M033689: view genomic region (about GC identifiers)

Start:	33,689,443 bp from pter	End:	33,714,762 bp from pter
Size:	25,320 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2 (See protein sequence)

Recommended Name: Inositol hexakisphosphate kinase 3

Size: 410 amino acids; 46417 Da

Subcellular location: Cytoplasm

Sequence caution: Sequence=BAB71225.2; Type=Frameshift; Positions=122;

Secondary accessions: Q96MQ9

Explore the universe of human proteins at neXtProt for IP6K3: NX_Q96PC2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96PC2

4/5 DME Specific Peptides for IP6K3 (Q96PC2) (see all 5)

CGMQVYQ

FGLENLI

SYRFYSSS

LDLKMGTRQ

IP6K3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001136355.1 NP_473452.2

ENSEMBL proteins:

ENSP00000293756 ENSP00000398861

Reactome Protein details: Q96PC2
Human Recombinant Protein Products for IP6K3:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals IP6K3 Lysates
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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for IP6K3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IDA	11502751

IP6K3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for IP6K3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IP6K3 for domains About GeneDecksing

1 InterPro domain/family:

IPR005522 IPK

Graphical View of Domain Structure for InterPro Entry Q96PC2

ProtoNet protein and cluster: Q96PC2

1 Blocks protein family: IPB005522 Inositol polyphosphate kinase

UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2

Similarity: Belongs to the inositol phosphokinase (IPK) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: IP6K3_HUMAN, Q96PC2

Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts

1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4

Catalytic activity: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 5-diphosphate

1,2,3,4,6-pentakisphosphate

Catalytic activity: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol diphosphate

tetrakisphosphate (isomeric configuration unknown)

Enzyme Number (IUBMB): EC 2.7.4.21¹ ²

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000831	inositol hexakisphosphate 6-kinase activity	IDA	11502751
GO:0000832	inositol hexakisphosphate 5-kinase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	IEA	--
GO:0052723	inositol hexakisphosphate 1-kinase activity	IEA	--

IP6K3 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for IP6K3:

Decreased focal adhesion (FA)

Decreased telomerase activity

Increased apoptosis

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for IP6K3

miRNA Products:		OriGene 3'-UTR Clone (see all 2): IP6K3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IP6K3
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate IP6K3 (see all 16):
		hsa-miR-30c hsa-miR-495 hsa-miR-30d hsa-miR-30a hsa-miR-298 hsa-miR-7-1* hsa-miR-1252 hsa-miR-3121-3p

		SwitchGear 3'UTR luciferase reporter plasmid: IP6K3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IP6K3 (see all 4) OriGene shRNA RFP: IP6K3 OriGene siRNA: IP6K3
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for IP6K3
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IP6K3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

inositol pyrophosphates biosynthesis

inositol pyrophosphates biosynthesis

1.00

Synthesis of pyrophosphates in the cytosol

0.42

Metabolism

Metabolism

1.00

Inositol phosphate metabolism

superpathway of inositol phosphate compounds

0.59

Synthesis of IP3 and IP4 in the cytosol

Inositol phosphate metabolism

0.57

Pathway sources
See GeneCards unified pathways
Show all pathways

2 BioSystems Pathways for IP6K3

	inositol pyrophosphates biosynthesis
	superpathway of inositol phosphate compounds

3 Reactome Pathways for IP6K3

	Metabolism
	Synthesis of pyrophosphates in the cytosol
	Inositol phosphate metabolism

IP6K3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for IP6K3

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/91 Interacting proteins for IP6K3 (Q96PC2³ ENSP00000293756⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 91)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HIST1H2BC	P62807³	I2D: score=1
HIST1H2BE	P62807³	I2D: score=1
HIST1H2BF	P62807³	I2D: score=1
HIST1H2BG	P62807³	I2D: score=1
HIST1H2BI	P62807³	I2D: score=1

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein phosphorylation	IDA	11502751
GO:0032958	inositol phosphate biosynthetic process	IDA	11502751
GO:0046488	phosphatidylinositol metabolic process	IDA	11502751

IP6K3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IP6K3

1 HMDB Compound for IP6K3 About this table

Compound	Synonyms	CAS #	PubMed Ids
1-Diphosinositol pentakisphosphate	D-myo-Inositol, 2,3,4,5,6-pentakis(dihydrogen phosphate);1-(trihydrogen diphosphate);Diphospho-myo-inositol pentakisphosphate	148077-18-3	--

Search CenterWatch for drugs/clinical trials and news about IP6K3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IP6K3 gene (2 alternative transcripts):

NM_001142883.1 NM_054111.4

Unigene Cluster for IP6K3:

Inositol hexakisphosphate kinase 3

Hs.17253 [show with all ESTs]

Unigene Representative Sequence: NM_001142883

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000293756 ENST00000451316(uc010jvf.2 uc003ofb.2)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): IP6K3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IP6K3
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate IP6K3 (see all 16):
		hsa-miR-30c hsa-miR-495 hsa-miR-30d hsa-miR-30a hsa-miR-298 hsa-miR-7-1* hsa-miR-1252 hsa-miR-3121-3p

		SwitchGear 3'UTR luciferase reporter plasmid: IP6K3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IP6K3 (see all 4) OriGene shRNA RFP: IP6K3 OriGene siRNA: IP6K3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IP6K3
		Sirion Biotech Custom design and validation of potent shRNA sequences against IP6K3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IP6K3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IP6K3 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): IP6K3 (NM_001142883)
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IP6K3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IP6K3

Additional cDNA sequence:

AF393812.1 AK056586.2 AK223572.1 AK289935.1 BC089389.1

2 DOTS entries:

DT.211368 DT.40118654

24/41 AceView cDNA sequences (see all 41):

AA344576 BI756662 AI075137 CR623666 AA344601 N52903 AW451702 AA036643

BM662703 BX431911 NM_054111 BX396754 BQ187027 BX354420 BM973856 AF393812

CO248865 BV192018 H48857 AK056586 BX396755 F24473 N69410 BX500702

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for IP6K3 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8a	·	8b
SP1:							-		-
SP2:							-		-				-		-		-		-		-
SP3:							-
SP4:							-		-
SP5:									-

ECgene alternative splicing isoforms for IP6K3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IP6K3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGACGCGGCT

About this image

IP6K3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor SK17 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See IP6K3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IP6K3

SOURCE GeneReport for Unigene cluster: Hs.17253

UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2

Tissue specificity: Detected in brain

SABiosciences Custom PCR Arrays for IP6K3

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IP6K3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IP6K3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for IP6K3 gene from 6/23 species (see all 23) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	IP6K3¹	inositol hexakisphosphate kinase 3	67.52(n) 62.66(a)		419908 XM_418033.3 XP_418033.2
lizard (Anolis carolinensis)	Reptilia	IP6K3⁶	--	61(a)	1 ↔ 1	4(123003228-123023619)
fruit fly (Drosophila melanogaster)	Insecta	CG10082⁶	--	14(a)	1 → many	2R(17533682-17545440)
worm (Caenorhabditis elegans)	Secernentea	F30A10.3⁶ Y22D7AR.6⁶ (see all 3)	Protein Y22D7AR.6 (see all 3)	33(a) 27(a) (see all 3)	many ↔ many many ↔ many (see all 3)	I(9492622-9494581) III(1672508-1676712)
thale cress (Arabidopsis thaliana)	eudicotyledons	ATIPK2A⁶ ATIPK2BETA⁶	inositol polyphosphate multikinase beta	27(a) 26(a)	many ↔ many many ↔ many	5(2330385-2332281) 5(24813729-24815443)
rice (Oryza sativa)	Liliopsida	--	inositol hexaphosphate kinase, putative, expressed...	23(a)	1 → many	2(19116035-19119974)

ENSEMBL Gene Tree for IP6K3 (if available)
TreeFam Gene Tree for IP6K3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for IP6K3 gene

IP6K1² IPMK² IP6K2²

3 SIMAP similar genes for IP6K3 using alignment to 2 protein entries: IP6K3_HUMAN (see all proteins):

IP6K1 IHPK2 IP6K2

IP6K3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs187062286^1,2		--	33689047(+)	`GTGAAC/TCTGCT`	2	--	ds500¹		0	--	--	--	--
rs145709937^1,2		--	33689059(+)	`AGAAAC/GCCATA`	2	--	ds500¹		0	--	--	--	--
rs141865026^1,2	C	--	33689097(+)	`TTTTG-/TTTTTT`	2	--	ds500¹		0	--	--	--	--
rs191808398^1,2		--	33689106(+)	`GTTTTG/TTTTGT`	2	--	ds500¹		0	--	--	--	--
rs75255454^1,2	F	--	33689174(+)	`TGTGGA/GTAGTA`	2	--	ds500¹		1		EA	120
rs114911682^1,2	F	--	33689185(+)	`ATTATC/TCATGA`	2	--	ds500¹		1		WA	118
rs73743310^1,2	C	--	33689299(+)	`CCACCA/GTTTCC`	2	--	ds500¹		3		WA NA	240
rs184097707^1,2		--	33689467(+)	`ATTAAC/TAAATT`	2	--	ut3¹		0	--	--	--	--
rs114078128^1,2		--	33689474(+)	`AATTTA/TTTTCC`	2	--	ut3¹		1		WA	118
rs2966^1,2	C,F,A,H	--	33689520(+)	`GGCATT/CGTAAT`	2	--	ut3¹		21		MN EA NS NA WA	4256

HapMap Linkage Disequilibrium report for IP6K3 (33689443 - 33714762 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IP6K3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IP6K3

DNA2.0 Custom Variant and Variant Library Synthesis for IP6K3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

IP6K3 for disorders           About GeneDecksing

OMIM gene information: 606993    OMIM disorders: --

3 diseases for IP6K3:    About MalaCards

systemic lupus erythematosus lupus erythematosus malaria

Human Genome Epidemiology (HuGE) Navigator: IP6K3 (2 documents)

Export disorders for IP6K3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for IP6K3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IP6K3)

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Identification and characterization of a novel inositol hexakisphosphate kinase. (PubMed id 11502751)^{1, 2, 3, 9} Saiardi A.... Snyder S.H. (2001)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Common genetic variants associate with serum phosphor us concentration. (PubMed id 20558539)¹ Kestenbaum B....Fox C.S. (2010)
High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)¹ Barcellos L.F....Criswell L.A. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)¹ Maruyama K. and Sugano S. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 117283	HGNC: 17269	AceView: IHPK3	Ensembl:ENSG00000161896	euGenes: HUgn117283
ECgene: IP6K3	H-InvDB: IP6K3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for IP6K3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for IP6K3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for IP6K3 gene:
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IP6K3 Gene

inositol hexakisphosphate kinase 3

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IP6K3 Gene

inositol hexakisphosphate kinase 3

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