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IP6K3 Gene

protein-coding   GIFtS: 56
GCID: GC06M033689

Inositol Hexakisphosphate Kinase 3

(Previous name: inositol hexaphosphate kinase 3)
(Previous symbol: IHPK3)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Inositol Hexakisphosphate Kinase 31 2     EC 2.7.4.213 8
IHPK31 2 3 5     INSP6K32 5
Inositol Hexaphosphate Kinase 31 2 3     ATP:1D-Myo-Inositol-Hexakisphosphate Phosphotransferase2
InsP6 Kinase 32 3     

External Ids:    HGNC: 172691   Entrez Gene: 1172832   Ensembl: ENSG000001618967   OMIM: 6069935   UniProtKB: Q96PC23   

Export aliases for IP6K3 gene to outside databases

Previous GC identifers: GC06M033798 GC06M033430


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IP6K3 Gene:
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely
responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate
(InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing
results in multiple transcript variants encoding the same protein.(provided by RefSeq, Dec 2008)

GeneCards Summary for IP6K3 Gene:
IP6K3 (inositol hexakisphosphate kinase 3) is a protein-coding gene. GO annotations related to this gene include inositol hexakisphosphate 1-kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. An important paralog of this gene is IP6K1.

UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2
Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).
Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IP6K3 gene promoter:
         Pbx1a   p53   HTF   FOXD1   Pax-2   Pax-2a   AP-4   AREB6   Msx-1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIP6K3 promoter sequence
   Search Chromatin IP Primers for IP6K3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IP6K3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

IP6K3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IP6K3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M033689:  view genomic region     (about GC identifiers)

Start:
33,689,443 bp from pter      End:
33,714,762 bp from pter
Size:
25,320 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2 (See protein sequence)
Recommended Name: Inositol hexakisphosphate kinase 3  
Size: 410 amino acids; 46417 Da
Sequence caution: Sequence=BAB71225.2; Type=Frameshift; Positions=122;
Secondary accessions: Q96MQ9

Explore the universe of human proteins at neXtProt for IP6K3: NX_Q96PC2

Explore proteomics data for IP6K3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for IP6K3 (Q96PC2) (see all 5)
     CGMQVYQ  FGLENLI  SYRFYSSS  LDLKMGTRQ 


    See IP6K3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001136355.1  NP_473452.2  

    ENSEMBL proteins: 
     ENSP00000293756   ENSP00000398861  
    Reactome Protein details: Q96PC2

    IP6K3 Human Recombinant Protein Products:

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    antibodies-online peptides for IP6K3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005522 IPK

    Graphical View of Domain Structure for InterPro Entry Q96PC2

    ProtoNet protein and cluster: Q96PC2

    1 Blocks protein domain: IPB005522 Inositol polyphosphate kinase

    UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2
    Similarity: Belongs to the inositol phosphokinase (IPK) family


    Find genes that share domains with IP6K3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IP6K3_HUMAN, Q96PC2
    Function: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).
    Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4
    Catalytic activity: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 5-diphosphate
    1,2,3,4,6-pentakisphosphate
    Catalytic activity: ATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol
    1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate

         Enzyme Number (IUBMB): EC 2.7.4.211 2

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000831inositol hexakisphosphate 6-kinase activity IDA11502751
    GO:0000832inositol hexakisphosphate 5-kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0008440inositol-1,4,5-trisphosphate 3-kinase activity IEA--
    GO:0052723inositol hexakisphosphate 1-kinase activity IEA--
         
    Find genes that share ontologies with IP6K3           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for IP6K3:
     Decreased focal adhesion (FA)   Decreased telomerase activity  Increased apoptosis 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for IP6K3

    miRNA
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    miRTarBase miRNAs that target IP6K3:
    hsa-mir-330-5p (MIRT038242)

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    Selected qRT-PCR Assays for microRNAs that regulate IP6K3 (see all 16):
    hsa-miR-30c hsa-miR-495 hsa-miR-30d hsa-miR-30a hsa-miR-298 hsa-miR-7-1* hsa-miR-1252 hsa-miR-3121-3p
    SwitchGear 3'UTR luciferase reporter plasmidIP6K3 3' UTR sequence
    Inhib. RNA
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    Addgene plasmids for IP6K3 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IP6K3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IP6K3_HUMAN, Q96PC2: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA11502751
    GO:0005829cytosol TAS--

    Find genes that share ontologies with IP6K3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IP6K3 About    
    See pathways by source

    SuperPathContained pathways About
    1Inositol phosphate metabolism (REACTOME)
    Inositol phosphate metabolism0.59
    Synthesis of pyrophosphates in the cytosol0.00
    inositol pyrophosphates biosynthesis0.00
    2Inositol phosphate metabolism (KEGG)
    superpathway of inositol phosphate compounds0.60
    3Metabolism
    Metabolism0.38


    Find genes that share SuperPaths with IP6K3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for IP6K3
        inositol pyrophosphates biosynthesis
    superpathway of inositol phosphate compounds

    1 Reactome Pathway for IP6K3
        Synthesis of pyrophosphates in the cytosol


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IP6K3
    Interactions:

        Search GeneGlobe Interaction Network for IP6K3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for IP6K3 (Q96PC23 ENSP000002937564) via UniProtKB, MINT, STRING, and/or I2D (see all 114)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H2BCP628073I2D: score=1 
    HIST1H2BEP628073I2D: score=1 
    HIST1H2BFP628073I2D: score=1 
    HIST1H2BGP628073I2D: score=1 
    HIST1H2BIP628073I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation IDA11502751
    GO:0032958inositol phosphate biosynthetic process IDA11502751
    GO:0043647inositol phosphate metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046488phosphatidylinositol metabolic process IDA11502751

    Find genes that share ontologies with IP6K3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for IP6K3

    1 HMDB Compound for IP6K3    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Diphosinositol pentakisphosphateD-myo-Inositol, 2,3,4,5,6-pentakis(dihydrogen phosphate);1-(trihydrogen diphosphate);Diphospho-myo-inositol pentakisphosphate 148077-18-3--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IP6K3 gene (2 alternative transcripts): 
    NM_001142883.1  NM_054111.4  

    Unigene Cluster for IP6K3:

    Inositol hexakisphosphate kinase 3
    Hs.17253  [show with all ESTs]
    Unigene Representative Sequence: NM_001142883
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293756 ENST00000451316(uc010jvf.2 uc003ofb.2)
    miRNA
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    hsa-miR-30c hsa-miR-495 hsa-miR-30d hsa-miR-30a hsa-miR-298 hsa-miR-7-1* hsa-miR-1252 hsa-miR-3121-3p
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      QuantiFast Probe-based Assays in human, mouse, rat IP6K3

    Additional mRNA sequence: 

    AF393812.1 AK056586.2 AK223572.1 AK289935.1 BC089389.1 

    2 DOTS entries:

    DT.211368  DT.40118654 

    Selected AceView cDNA sequences (see all 41):

    AA344576 BI756662 AI075137 CR623666 AA344601 BV192018 BM662703 AA036643 
    NM_054111 AW451702 BX396755 H48857 BX431911 AF393812 AK056586 CO248865 
    BM973856 BQ187027 BX354420 N52903 BX396754 BX500702 N69410 F24473 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for IP6K3    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:                    -     -                                                               
    SP2:                    -     -           -     -     -     -     -                           
    SP3:                    -                                                                     
    SP4:                    -     -                                                               
    SP5:                          -                                                               


    ECgene alternative splicing isoforms for IP6K3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IP6K3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGACGCGGCT
    IP6K3 Expression
    About this image


    IP6K3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Adipose (Muscoskeletal System)
             HyStem+BMP4-induced 7SMOO32 cells
    IP6K3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IP6K3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.17253

    UniProtKB/Swiss-Prot: IP6K3_HUMAN, Q96PC2
    Tissue specificity: Detected in brain

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IP6K3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for IP6K3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ip6k31 , 5 inositol hexaphosphate kinase 31, 5 82.18(n)1
    78.77(a)1
      17 (13.77 cM)5
    2714241  NM_173027.21  NP_766615.11 
     271439695 
    chicken
    (Gallus gallus)
    Aves IP6K31 inositol hexakisphosphate kinase 3 67.43(n)
    62.92(a)
      419908  XM_418033.4  XP_418033.2 
    lizard
    (Anolis carolinensis)
    Reptilia IP6K36
    inositol hexakisphosphate kinase 3
    61(a)
    1 ↔ 1
    4(122995200-123025291)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG100826
    --
    16(a)
    1 → many
    2R(17533682-17545440)
    worm
    (Caenorhabditis elegans)
    Secernentea F30A10.36
    Y22D7AR.66
    (see all 3)
    Protein Y22D7AR.6 (Y22D7AR.6) mRNA, complete cds
    (see all 3)
    33(a)
    29(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    I(9492630-9494589) WBGene00009262
    III(1672517-1676721) WBGene00021260
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes KCS1(YDR017C)4 Inositol hexakisphosphate (IP6) and inositol heptakisphosphate more   --   4(482267-479115) 851580  NP_010300.1 


    ENSEMBL Gene Tree for IP6K3 (if available)
    TreeFam Gene Tree for IP6K3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IP6K3 gene
    IP6K12  IPMK2  IP6K22  
    3 SIMAP similar genes for IP6K3 using alignment to 2 protein entries:     IP6K3_HUMAN (see all proteins):
    IP6K1    IHPK2    IP6K2

    Find genes that share paralogs with IP6K3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IP6K3 (see all 722)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1870622861,2
    --33689047(+) GTGAAC/TCTGCT 2 -- ds50010--------
    rs1457099371,2
    --33689059(+) AGAAAC/GCCATA 2 -- ds50010--------
    rs1418650261,2
    C--33689101(+) TTTTT-/TGTTTT 2 -- ds50010--------
    rs1918083981,2
    C--33689106(+) GTTTTG/TTTTGT 2 -- ds50010--------
    rs752554541,2
    C,F--33689174(+) TGTGGA/GTAGTA 2 -- ds50011Minor allele frequency- G:0.02EA 120
    rs1149116821,2
    F--33689185(+) ATTATC/TCATGA 2 -- ds50011Minor allele frequency- T:0.02WA 118
    rs737433101,2
    C,F--33689299(+) CCACCA/GTTTCC 2 -- ds50013Minor allele frequency- G:0.04WA NA 240
    rs1840977071,2
    --33689467(+) ATTAAC/TAAATT 2 -- ut310--------
    rs1140781281,2
    C,F--33689474(+) AATTTA/TTTTCC 2 -- ut311Minor allele frequency- T:0.01WA 118
    rs29661,2
    C,F,A,H--33689520(+) GGCATT/CGTAAT 2 -- ut3121Minor allele frequency- C:0.41MN EA NS NA WA 4256

    HapMap Linkage Disequilibrium report for IP6K3 (33689443 - 33714762 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for IP6K3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509128CNV Insertion20534489
    dgv85n68CNV Loss17160897
    nsv885772CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606993    OMIM disorders: --


    Find genes that share disorders with IP6K3           About GenesLikeMe

    Genetic Association Database (GAD): IP6K3
    Human Genome Epidemiology (HuGE) Navigator: IP6K3 (2 documents)

    Export disorders for IP6K3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IP6K3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with IP6K3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a novel inositol hexakisphosphate kinase. (PubMed id 11502751)1, 2, 3, 9 Saiardi A.... Snyder S.H. (J. Biol. Chem. 2001)
    2. Common genetic variants associate with serum phosphorus concentration. (PubMed id 20558539)1, 4 Kestenbaum B....Fox C.S. (J. Am. Soc. Nephrol. 2010)
    3. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations. (PubMed id 23850713)1 Yang S.K....Song K. (Gut 2014)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 117283 HGNC: 17269 AceView: IHPK3 Ensembl:ENSG00000161896 euGenes: HUgn117283
    ECgene: IP6K3 H-InvDB: IP6K3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for IP6K3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for IP6K3 gene:
    Search GeneIP for patents involving IP6K3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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