Aliases for IP6K2 Gene
External Ids for IP6K2 Gene
Previous HGNC Symbols for IP6K2 Gene
Previous GeneCards Identifiers for IP6K2 Gene
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for IP6K2 Gene
IP6K2 (Inositol Hexakisphosphate Kinase 2) is a Protein Coding gene. Diseases associated with IP6K2 include Ovarian Cancer, Somatic. Among its related pathways are Metabolism and Inositol phosphate metabolism (KEGG). GO annotations related to this gene include inositol-1,4,5-trisphosphate 3-kinase activity and inositol hexakisphosphate 1-kinase activity. An important paralog of this gene is IP6K1.
UniProtKB/Swiss-Prot for IP6K2 Gene
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.