INTS3 Gene
protein-coding GIFtS : 48 GCID: GC01 P153700
integrator complex subunit 3 chromosome 1 open reading frame 60 )C1orf60 )
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Aliasesfor INTS3 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Integrator Complex Subunit 3 1 2 SOSS Complex Subunit A2 3 C1orf601 2 3 FLJ219191 SOSS-A1 2 3 Chromosome 1 Open Reading Frame 601 INT31 2 RP11-216N14.42 Sensor Of Single-Strand DNA Complex Subunit A2 3 Sensor Of SsDNA A2 Sensor Of SsDNA Subunit A2 3 Int33 C1orf1932 3
Export aliases for INTS3 gene to outside databases Previous GC identifers: GC01P151967 GC01P125063
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Summariesfor INTS3 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for INTS3 : INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)). INTS3 is also a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability (Huang et al., 2009) (PubMed 19683501).(supplied by OMIM, Feb 2010) UniProtKB/Swiss-Prot: INT3_HUMAN, Q68E01 Function : Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes Function : Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promoteDNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites Gene Wiki entry for INTS3
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Genomic Viewsfor INTS3 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_004487.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the INTS3 gene promoter:GR E2F-4 E2F-3a E2F-5 GR-beta CUTL1 E2F-2 E2F E2F-1 GR-alpha Other transcription factors Search SABiosciences Chromatin IP Primers for INTS3 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INTS3
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.3 INTS3 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P153700: view genomic region
(about GC identifiers )
Start: 153,700,543 bp from pter End:
153,746,555 bp from pter
Size: 46,013 bases Orientation:
plus strand
1 alternative location : Chr 1+,PATCHES 153,717,809-153,763,797
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Proteinsfor INTS3 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: INT3_HUMAN, Q68E01 See
protein sequence )Recommended Name: Size : 1043 amino acids; 118070 DaSubunit : Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6,INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Component of the SOSS complex, composed of SOSS-B (SOSS-B1/NABP2 or SOSS-B2/NABP1), SOSS-A/INTS3 and SOSS-C/INIP. SOSS complexes containing SOSS-B1/NABP2 are more abundant than complexes containing SOSS-B2/NABP1. Interacts with SOSS-B1/NABP2, SOSS-B2/NABP1 and SOSS-C/INIP; the interaction is direct. Interacts with NBN/NBS1
Subcellular location : Nucleus. Note=Localizes to nuclear foci following DNA damageSequence caution : Sequence=AAH25254.1; Type=Erroneous initiation; Sequence=AAH54513.1; Type=Erroneous initiation;Sequence=BAB15174.1; Type=Erroneous initiation; Sequence=BAC11329.1; Type=Erroneous initiation; Sequence=CAH18229.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=CAH71415.1; Type=Erroneous gene model prediction; Sequence=CAH71417.1; Type=Erroneous gene model prediction; Sequence=CAH71418.1; Type=Erroneous gene model prediction;
Secondary accessions : A8K1W0 B4DQC8 B4E3U9 D3DV57 Q4G0E5 Q5VUQ5 Q5VUQ6 Q5VUR0 Q5VUR1 Q68DJ1 Q69YR5Q6AI57 Q6DKG7 Q6MZQ4 Q6MZZ9 Q8NC46 Q8TB23 Q9H6S9 Alternative splicing : 4 isoforms : Q68E01-1 Q68E01-2 Q68E01-3 Q68E01-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for INTS3: NX_Q68E01 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q68E01 INTS3 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_075391.3 ENSEMBL proteins: ENSP00000318641 ENSP00000404290 ENSP00000425437 ENSP00000422616 ENSP00000398222 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing INTS3 Antibody Products: Assay Products for INTS3:
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Protein
Domains /for INTS3 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q68E01 ProtoNet protein and cluster: Q68E01
UniProtKB/Swiss-Prot: INT3_HUMAN, Q68E01 Similarity : Belongs to the Integrator subunit 3 family
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Functionfor INTS3 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: INT3_HUMAN, Q68E01 Function : Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes Function : Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promoteDNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites
Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: INTS3 (NM_023015 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for INTS3 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat INTS3
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS3
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
About GeneDecksing
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Pathways & Interactionsfor INTS3 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for INTS3 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/773 Interacting proteins for INTS3 (Q68E01 2 , 3 ENSP00000318641 4 via UniProtKB, MINT, STRING , and/or I2D (see all 773 )About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
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Drugs & Compoundsfor INTS3 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for INTS3 10/67 Novoseek chemical compound relationships for INTS3 gene (see all 67 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
2-(hydroxymethyl)pyridine
89.7
1
16411688 (1)
dppz
80.3
2
19050783 (1)
2,2'-bipyridine
79.2
5
15934758 (1), 15149244 (1), 16363818 (1), 20199051 (1)
acetonitrile
71.6
7
18648705 (1), 18841928 (1), 12184772 (1), 17173448 (1) (see all 7 )
1,10-phenanthroline
71.6
5
15356721 (1), 19254037 (1), 15149244 (1), 17058961 (1)
carboxylate
68.2
6
11187465 (1), 17387398 (1), 17988122 (1), 16676952 (1) (see all 5 )
copper(i)
68.1
3
16097834 (1), 12691587 (1)
pyridine
66.1
5
18648705 (1), 18975873 (1), 18844344 (1), 19234747 (1)
dicyanamide
64.7
1
20141179 (1)
hydride
63.1
5
18060114 (1), 20000856 (1), 17563789 (1), 11724599 (1) (see all 5 )
INTS3 / INT3
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Transcriptsfor INTS3 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for INTS3 gene: NM_023015.3 Unigene Cluster for INTS3:
Integrator complex subunit 3 Hs.516522 [show with all ESTs ] Unigene Representative Sequence: CR749376 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000318967 (uc009wom.3 uc001fct.3 ) ENST00000435409 ENST00000481797 (uc001fcu.3 uc001fcv.3 )ENST00000512605 ENST00000476843 (uc001fcw.3 uc010pec.2 ) ENST00000480659 ENST00000503133 ENST00000491790 ENST00000368670 (uc001fcx.3 uc001fcy.3 )ENST00000368669 ENST00000456435 (uc010peb.2 ) Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: INTS3 (NM_023015 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for INTS3 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat INTS3
Additional cDNA sequence: AF130066.2 AK025572.1 AK055174.1 AK074979.1 AK091908.1 AK094402.1 AK126799.1 AK225294.1 AK290025.1 AK298746.1 AK304874.1 AL080172.1 AL832133.1 BC025254.1 BC054513.1 BC073985.1 BC098431.1 BC105092.1 BC105094.1 BC116458.1 BX640786.1 BX640950.1 CR627233.1 CR749212.1 CR749376.1
21 DOTS entries : DT.100713671 DT.95236436
DT.75173419 DT.91888334 DT.447918 DT.97791520 DT.100028537 DT.101983862 DT.121390581 DT.75155374 DT.100791259 DT.99932903 DT.101983861 DT.121390718 DT.92444285 DT.92444288 DT.121390725 DT.40248431 DT.91968365 DT.100811416 DT.95076529 24/393 AceView cDNA sequences (see all 393 ):
BU145596 BM559002 BE409098 CR623345 BQ213055 BP367886 BQ961427 BC025254 AI133561 BC003041 BC054513 BX110564 AA282429 BC073985 BE276851 BM473894 BQ721318 BM707899 BQ672656 BM727185 AI292150 BF514665 CR749212 BG258327 GeneLoc Exon Structure 5/16 Alternative Splicing Database (ASD) splice patterns (SP) for INTS3 (see all 16 ) About this scheme ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ SP1 : - - - - - - - - - SP2 : SP3 : SP4 : - - - - SP5 : -
ExUns: 14 ^ 15a · 15b · 15c ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 SP1 : SP2 : - - SP3 : - - SP4 : SP5 :
ECgene alternative splicing isoforms for INTS3
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Expression for INTS3 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section INTS3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGGCAGATGC
About this image INTS3 expression in embryonic tissues and stem cells About this table 1 LifeMap In Vivo Development Anatomical Compartment/CellTissue Category (developmental path) Reproductive System Early Gonad Testis Somatic Cells Testis Expression: Experimental details:
In-situ hybridization
See INTS3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for INTS3 SOURCE GeneReport for Unigene cluster: Hs.516522 SABiosciences Custom PCR Arrays for INTS3 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS3
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Orthologsfor INTS3 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for INTS3 gene from 9/25 species (see all 25 ) About this table
ENSEMBL Gene Tree for INTS3 (if available)TreeFam Gene Tree for INTS3 (if available)
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Paralogsfor INTS3 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section
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Genomic Variantsfor INTS3 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 1 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for INTS3 (153700543 - 153746555 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for INTS3 1 CNV 39015
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor INTS3 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 611347
OMIM disorders : --11 : About MalaCards epilepsies, partial trigonitis respiratory failure diabetes mellitus vaginitis hepatocellular carcinoma myopathy hypertension cholesterol carcinoma alcoholism 5 Novoseek disease relationships for INTS3 gene About this table
Export disorders for INTS3 gene to outside databases
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Publicationsfor INTS3 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for INTS3 gene, integrated from 9 sources (see all 244 ):(articles sorted by number of sources associating them with INTS3) Utopia : connect your pdf to the dynamic
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. (PubMed id 16239144) 1 , 2 , 3(2005) hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response. (PubMed id 19605351) 1 , 2 (2009) SOSS complexes participate in the maintenance of genomic stability. (PubMed id 19683501) 1 , 2 (2009) The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 1 , 2 (2006) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) A census of human soluble protein complexes. (PubMed id 22939629) 1 (2012) Initial characterization of the human central proteome. (PubMed id 21269460) 2 (2011) Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764) 1 (2011) Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943) 1 (2011)
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External Searches for INTS3 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing INTS3 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing INTS3 gene
(According to HUGE )
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Specialized Databases showing INTS3 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for INTS3 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for INTS3 gene: INTS3 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor INTS3 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies Browse OriGene shRNA RFPs OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for INTS3 OriGene 3'-UTR Clone for INTS3 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for INTS3 OriGene Custom Protein Services for INTS3 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat INTS3 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INTS3 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for INTS3
INTS3 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS3
Search ThermoFisher Antibodies for INTS3
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat INTS3
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Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
In-situ hybridization
