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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

INTS12 Gene

protein-coding   GIFtS: 50
GCID: GC04M106603

Integrator Complex Subunit 12

(Previous name: PHD finger protein 22)
(Previous symbol: PHF22)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Integrator Complex Subunit 121 2
PHF221 2 3
PHD Finger Protein 221 2 3
Hypothetical Nuclear Factor SBBI221 2
INT122
Int123

External Ids:    HGNC: 250671   Entrez Gene: 571172   Ensembl: ENSG000001387857   OMIM: 6113555   UniProtKB: Q96CB83   

Export aliases for INTS12 gene to outside databases

Previous GC identifers: GC04M106823 GC04M102338


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for INTS12 Gene:
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II
large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM
180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)

GeneCards Summary for INTS12 Gene: 
INTS12 (integrator complex subunit 12) is a protein-coding gene. Diseases associated with INTS12 include trigonitis, and urethritis. GO annotations related to this gene include protein binding and zinc ion binding.

UniProtKB/Swiss-Prot: INT12_HUMAN, Q96CB8
Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2
transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal
domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes

Gene Wiki entry for INTS12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the INTS12 gene promoter:
         HSF1 (long)   XBP-1   Cdc5   LCR-F1   S8   POU2F1   POU2F1a   FOXO4   HSF1short   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidINTS12 promoter sequence
   Search SABiosciences Chromatin IP Primers for INTS12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INTS12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q24   Ensembl cytogenetic band:  4q24   HGNC cytogenetic band: 4q24

INTS12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
INTS12 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M106603:  view genomic region     (about GC identifiers)

Start:
106,603,784 bp from pter      End:
106,817,143 bp from pter
Size:
213,360 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: INT12_HUMAN, Q96CB8 (See protein sequence)
Recommended Name: Integrator complex subunit 12  
Size: 462 amino acids; 48808 Da
Subunit: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5,
INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAF99604.1; Type=Frameshift; Positions=439;
Secondary accessions: B2RC48 Q3B6Z3 Q9HD71

Explore the universe of human proteins at neXtProt for INTS12: NX_Q96CB8

Explore proteomics data for INTS12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96CB8

  • INTS12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    INTS12 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001135943.1  NP_065128.2  

    ENSEMBL proteins: 
     ENSP00000378221   ENSP00000340737   ENSP00000415433   ENSP00000423618   ENSP00000412317  
     ENSP00000396309   ENSP00000396729   ENSP00000422856   ENSP00000422048  

    Human Recombinant Protein Products for INTS12: 
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    Novus Biologicals INTS12 Lysates
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for INTS12 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032039integrator complex IDA16239144

    INTS12 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PHF: Zinc fingers, PHD-type

    5 InterPro protein domains:
     IPR001965 Znf_PHD
     IPR013083 Znf_RING/FYVE/PHD
     IPR019786 Zinc_finger_PHD-type_CS
     IPR011011 Znf_FYVE_PHD
     IPR019787 Znf_PHD-finger

    Graphical View of Domain Structure for InterPro Entry Q96CB8

    ProtoNet protein and cluster: Q96CB8

    1 Blocks protein domain: IPB001965 Zn-finger-like

    UniProtKB/Swiss-Prot: INT12_HUMAN, Q96CB8
    Similarity: Contains 1 PHD-type zinc finger


    INTS12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: INT12_HUMAN, Q96CB8
    Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2
    transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal
    domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16239144
    GO:0008270zinc ion binding IEA--
         
    INTS12 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ints12):
     mortality/aging 

    INTS12 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for INTS12 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for INTS12

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for INTS12 
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of INTS12

    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for INTS12

    5/619 Interacting proteins for INTS12 (Q96CB82, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 619)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    INTS1Q8N2012, 3MINT-7945693 I2D: score=1 
    INTS3Q68E012, 3MINT-7945693 I2D: score=1 
    GATAD2BQ8WXI92MINT-7945693 MINT-8173832
    PRPF6O949062MINT-7945693 MINT-8173832
    AXIN1O151693I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016180snRNA processing IDA16239144

    INTS12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for INTS12 (INT12)

    Search CenterWatch for drugs/clinical trials and news about INTS12 / INT12

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for INTS12 gene (2 alternative transcripts): 
    NM_001142471.1  NM_020395.3  

    Unigene Cluster for INTS12:

    Integrator complex subunit 12
    Hs.480454  [show with all ESTs]
    Unigene Representative Sequence: NM_020395
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394735 ENST00000340139(uc003hxw.3) ENST00000451321(uc010ilr.3)
    ENST00000493425 ENST00000503746 ENST00000420368 ENST00000416543 ENST00000433009
    ENST00000510876 ENST00000515819
    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate INTS12
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for INTS12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat INTS12
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): INTS12 (NM_001142471)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INTS12
    Sirion Biotech Customized lentivirus for stable overexpression of INTS12 
                         Customized lentivirus expression plasmids for stable overexpression of INTS12 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for INTS12
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INTS12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INTS12

    Additional mRNA sequence: 

    AF242524.1 AK314939.1 BC014442.1 

    9 DOTS entries:

    DT.100809930  DT.317035  DT.95268072  DT.75117298  DT.121240650  DT.92429662  DT.100809928  DT.86836954 
    DT.92429661 

    24/169 AceView cDNA sequences (see all 169):

    F02139 CB133817 AW150186 AA814728 AA634213 BQ213189 AA252535 AI248038 
    CD369828 Z42635 Z44438 CA440207 BI255383 AA903217 BM805289 BX359444 
    CA437148 AA406286 CB156058 AA327849 BQ007545 BU607470 BM727749 CA448208 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    INTS12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGATGGGAT
    INTS12 Expression
    About this image


    See INTS12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for INTS12

    SOURCE GeneReport for Unigene cluster: Hs.480454
        SABiosciences Custom PCR Arrays for INTS12
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for INTS12 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ints121 , 5 integrator complex subunit 121, 5 88.43(n)1
    91.54(a)1
      3 (61.56 cM)5
    717931  NM_027927.31  NP_082203.11 
     1330918405 
    chicken
    (Gallus gallus)
    Aves INTS121 integrator complex subunit 12 76.52(n)
    80.83(a)
      422537  XM_420500.3  XP_420500.2 
    lizard
    (Anolis carolinensis)
    Reptilia INTS126
    Uncharacterized protein
    79(a)
    1 ↔ 1
    GL343375.1(272083-284287)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.136192 Xenopus laevis transcribed sequence with weak similarity more 74.94(n)    BJ618403.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003347131 integrator complex subunit 12-like 60.67(n)
    64.47(a)
      100334713  XM_002660463.2  XP_002660509.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta IntS121 Integrator 12 39.67(n)
    33.45(a)
      43227  NM_143250.2  NP_651507.1 


    ENSEMBL Gene Tree for INTS12 (if available)
    TreeFam Gene Tree for INTS12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/474 SNPs in INTS12 are shown (see all 474)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1477797651,2
    --106603539(+) GCCACA/GTAAGG 2 -- int10--------
    rs766124851,2
    C,F--106603753(+) TAATAT/CTTAGC 2 -- int12Minor allele frequency- C:0.12WA NA 238
    rs798665481,2
    C--106603861(+) AGGCTA/GATATG 2 -- ut310--------
    rs342345811,2
    C,F--106603935(+) ATCTGT/CAATCG 4 /L syn13Minor allele frequency- C:0.01NA WA 4730
    rs1451748071,2
    C,F--106604070(+) CCATTC/TCCACT 4 G syn12Minor allele frequency- T:0.00NA EU 5875
    rs1153026481,2
    C,F--106604164(+) TAAGGC/ACAGTT 4 /G /V mis13Minor allele frequency- A:0.00NA EU 5993
    rs353707431,2
    C,F--106604190(+) GGTGGA/GGGTGG 4 P syn15Minor allele frequency- G:0.05NA EU 6073
    rs100081581,2
    C,H--106604223(+) GTGCTG/ATTATT 4 /N syn1 ese36Minor allele frequency- A:0.00NS EA NA 424
    rs1849868131,2
    C--106604227(+) TGTTAC/TTGGAA 4 N S mis10--------
    rs1476141651,2
    C--106604308(+) CTGACA/GAAGTA 4 S L mis10--------

    HapMap Linkage Disequilibrium report for INTS12 (106603784 - 106817143 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for INTS12:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv879699CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing INTS12
    DNA2.0 Custom Variant and Variant Library Synthesis for INTS12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611355    OMIM disorders: --

    5 diseases for INTS12:    About MalaCards
    trigonitis    urethritis    scoliosis    alcohol dependence
    alcoholism


    INTS12 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for INTS12 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma 9.61 3 9352443 (1), 9553811 (1)

    Genetic Association Database (GAD): INTS12
    Human Genome Epidemiology (HuGE) Navigator: INTS12 (2 documents)

    Export disorders for INTS12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for INTS12 gene, integrated from 9 sources (see all 39):
    (articles sorted by number of sources associating them with INTS12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. (PubMed id 16239144)1, 2, 3 Baillat D....Shiekhattar R. (2005)
    2. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    3. Meta-analyses of genome-wide association studies iden tify multiple loci associated with pulmonary function. (PubMed id 20010835)1, 4 Hancock D.B....London S.J. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Genome-wide joint meta-analysis of SNP and SNP-by-smok ing interaction identifies novel loci for pulmonary function. (PubMed id 23284291)1 Hancock D.B....London S.J. (2012)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
    9. Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (2011)
    10. Streamlined analysis schema for high-throughput ident ification of endogenous protein complexes. (PubMed id 20133760)1 Malovannaya A....Qin J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57117 HGNC: 25067 AceView: LOC57117 Ensembl:ENSG00000138785 euGenes: HUgn57117
    ECgene: INTS12 H-InvDB: INTS12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for INTS12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for INTS12 gene:
    Search GeneIP for patents involving INTS12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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