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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

INTS10 Gene

protein-coding   GIFtS: 46
GCID: GC08P019674

integrator complex subunit 10

(Previous name: chromosome 8 open reading frame 35 )
(Previous symbol: C8orf35)
 Explore 10 diseases affiliated with
INTS10 via our new
 Human Malady Compendium 
Biological research products
for INTS10
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Integrator Complex Subunit 101 2
C8orf351 2 3
INT101 2
FLJ105691
Chromosome 8 Open Reading Frame 351
Int103

External Ids:    HGNC: 255481   Entrez Gene: 551742   Ensembl: ENSG000001046137   OMIM: 6113535   UniProtKB: Q9NVR23   

Export aliases for INTS10 gene to outside databases

Previous GC identifers: GC08P019721 GC08P018215


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for INTS10:
INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large
subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2
(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: INT10_HUMAN, Q9NVR2
Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2
transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal
domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the INTS10 gene promoter:
         HTF   CUTL1   Evi-1   Roaz   HNF-1A   AREB6   HNF-1   FOXO1a   MRF-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidINTS10 promoter sequence
   Search SABiosciences Chromatin IP Primers for INTS10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INTS10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.3   Ensembl cytogenetic band:  8p21.3   HGNC cytogenetic band: 8p21.3

INTS10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
INTS10 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P019674:  view genomic region     (about GC identifiers)

Start:
19,674,651 bp from pter      End:
19,709,594 bp from pter
Size:
34,944 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: INT10_HUMAN, Q9NVR2 (See protein sequence)
Recommended Name: Integrator complex subunit 10  
Size: 710 amino acids; 82236 Da
Subunit: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6,
INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with POLR2A
Subcellular location: Nucleus
Sequence caution: Sequence=BAA91687.1; Type=Frameshift; Positions=90; Sequence=CAG33543.1; Type=Erroneous initiation;
Secondary accessions: Q6IA93 Q7L538 Q7L8C8 Q9H3W8

Explore the universe of human proteins at neXtProt for INTS10: NX_Q9NVR2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NVR2

  • INTS10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060612.2  
    ENSEMBL proteins: 
     ENSP00000381064   ENSP00000429011   ENSP00000430877   ENSP00000428107   ENSP00000430446  
     ENSP00000430704   ENSP00000429534   ENSP00000429117   ENSP00000428300   ENSP00000428608  
     ENSP00000428671  

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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for INTS10

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0032039integrator complex IDA16239144


    INTS10 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    INTS10 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026164 Int_cplx_su10

    Graphical View of Domain Structure for InterPro Entry Q9NVR2

    ProtoNet protein and cluster: Q9NVR2

    UniProtKB/Swiss-Prot: INT10_HUMAN, Q9NVR2
    Similarity: Belongs to the Integrator subunit 10 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: INT10_HUMAN, Q9NVR2
    Function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2
    transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal
    domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes

    miRNA
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515contributes to protein binding IPI16239144


    INTS10 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for INTS10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/27 Interacting proteins for INTS10 (Q9NVR23 ENSP000003810644) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    INTS5Q6P9B93, ENSP000003278894I2D: score=1 STRING: ENSP00000327889
    INTS1Q8N2013, ENSP000003857224I2D: score=1 STRING: ENSP00000385722
    INTS3Q68E013, ENSP000003186414I2D: score=1 STRING: ENSP00000318641
    INTS6Q9UL033, ENSP000003102604I2D: score=1 STRING: ENSP00000310260
    RAF1P040493, ENSP000002518494I2D: score=3 STRING: ENSP00000251849
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016180snRNA processing IDA16239144


    INTS10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    INTS10 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for INTS10
    1 Novoseek chemical compound relationship for INTS10 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    acetonitrile 18.1 1 11446650 (1)

    Search CenterWatch for drugs/clinical trials and news about INTS10 / INT10 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for INTS10 gene: 
    NM_018142.2  

    Unigene Cluster for INTS10:

    Integrator complex subunit 10
    Hs.512627  [show with all ESTs]
    Unigene Representative Sequence: NM_018142
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397977(uc003wzj.3 uc022asn.1) ENST00000518424 ENST00000522114
    ENST00000520985 ENST00000521758 ENST00000523869 ENST00000522081 ENST00000523846
    ENST00000522806 ENST00000523143 ENST00000521357 ENST00000518799 ENST00000519493
    ENST00000520670 ENST00000521008 ENST00000523772 ENST00000520827 ENST00000517546


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    Additional cDNA sequence: 

    AK001431.1 AK092931.1 AL442078.1 BC001915.1 BC006209.2 BC051282.1 CR457262.1 

    17 DOTS entries:

    DT.86853013  DT.121473255  DT.100790454  DT.40204495  DT.70103735  DT.87046885  DT.40294731  DT.86853012 
    DT.95107986  DT.100790452  DT.40301370  DT.121473237  DT.121473261  DT.100028254  DT.121473247  DT.100028255 
    DT.95228022 

    24/339 AceView cDNA sequences (see all 339):

    AW294232 BM854480 AI085028 CA308043 AA553813 BM681957 BC001915 AA131472 
    BQ636691 AI498247 BX484086 AI420987 BM756097 AA702327 BM547763 BQ673848 
    CB216206 BQ440275 BX281308 AW160632 AW952465 CA950715 BE514684 AI245586 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for INTS10 (see all 15)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b ^
    SP1:              -           -     -                                   -                                         -     -                                       
    SP2:                                                                                                                                      -     -               
    SP3:                                                                                                        -     -     -                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                              -     -                                       

    ExUns: 11 ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19a · 19b · 19c
    SP1:                          -     -                             -     -                     
    SP2:                          -     -                                                         
    SP3:                                                                                          
    SP4:                          -                                                               
    SP5:                                                                                          


    ECgene alternative splicing isoforms for INTS10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    INTS10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCACAGAGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    INTS10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Reproductive SystemMesonephrosMesonephric cellsReproductive System
    KidneyMetanephrosKidney
    Reproductive SystemMesonephrosReproductive System
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See INTS10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for INTS10

    SOURCE GeneReport for Unigene cluster: Hs.512627
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INTS10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for INTS10 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ints101 , 5 integrator complex subunit 101, 5 87.32(n)1
    95.77(a)1
      8 (33.88 cM)5
    708851  NM_027590.31  NP_081866.11 
     687939295 
    chicken
    (Gallus gallus)
    Aves INTS101 integrator complex subunit 10 81.55(n)
    90.7(a)
      422489  NM_001039297.1  NP_001034386.1 
    lizard
    (Anolis carolinensis)
    Reptilia INTS106
    --
    87(a)
    1 ↔ 1
    6(58912473-58940273)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.158162 Xenopus laevis transcribed sequence with moderate similarity more 76.69(n)    BX846187.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.282112 Danio rerio hypothetical protein FLJ10569-like protein more 76.16(n)    AY391424.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta IntS101 Integrator 10 42.3(n)
    29.68(a)
      38444  NM_139573.1  NP_647830.1 


    ENSEMBL Gene Tree for INTS10 (if available)
    TreeFam Gene Tree for INTS10 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/692 NCBI SNPs in INTS10 are shown (see all 692    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1899596531,2
    --19672960(+) GTAAAA/CTCACT 1 -- us2k10--------
    rs1816761471,2
    --19672999(+) AGATGC/GCAGCA 1 -- us2k10--------
    rs1871378971,2
    --19673050(+) ATCAAG/TAAGCT 1 -- us2k10--------
    rs170915451,2
    C,F,H,--19673125(+) TTGGCA/TTCTAA 1 -- us2k110Minor allele frequency- T:0.09NA NS EA WA 800
    rs1919580071,2
    --19673151(+) TGGGCA/GCAATG 1 -- us2k10--------
    rs1833780111,2
    --19673222(+) GAGTTA/CAAGAA 1 -- us2k10--------
    rs1115532241,2
    C,--19673286(+) CAGATG/ATGGTG 1 -- us2k12Minor allele frequency- A:0.11NA WA 120
    rs1135676511,2
    --19673346(+) CTTGAA/GCCTGG 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1422844451,2
    C,--19673432(+) CTCAA-/AAAC  
            
    AAACA
    1 -- us2k10--------
    rs1425775481,2
    --19673606(+) TTTACC/TATTTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for INTS10 (19674651 - 19709594 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for INTS10: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    INTS10 for disorders           About GeneDecksing

    OMIM gene information: 611353    OMIM disorders: --

    10 diseases for INTS10:    About MalaCards
    neonatal ovarian cyst    ovarian cyst    acute lymphoblastic leukemia    lymphoblastic leukemia
    lupus erythematosus    thyroid carcinoma    thyroiditis    leukemia
    schizophrenia    carcinoma


    Export disorders for INTS10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for INTS10 gene, integrated from 9 sources (see all 56):
    (articles sorted by number of sources associating them with INTS10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. (PubMed id 16239144)1, 2, 3 Baillat D....Shiekhattar R. (2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Identification of germline susceptibility loci in ETV6 -RUNX1-rearranged childhood acute lymphoblastic leukemia. (PubMed id 22076464)1 Ellinghaus E....Franke A. (2012)
    5. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Streamlined analysis schema for high-throughput ident ification of endogenous protein complexes. (PubMed id 20133760)1 Malovannaya A....Qin J. (2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    10. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55174 HGNC: 25548 AceView: FLJ10569 Ensembl:ENSG00000104613 euGenes: HUgn55174
    ECgene: INTS10 H-InvDB: INTS10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for INTS10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for INTS10 gene:
    Search GeneIP for patents involving INTS10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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