INSRR Gene
protein-coding GIFtS: 62
GCID: GC01M156809
|
|
insulin receptor-related receptor
| |
Aliases
for INSRR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Insulin Receptor-Related Receptor1 2 | | IRR1 2 3 5 | | IR-Related Receptor2 3 | | EC 2.7.10.13 8 | | Insulin Receptor-Related Protein2 | | EC 2.7.108 |
Export aliases for INSRR gene to outside databasesPrevious GC identifers: GC01M154679 GC01M152575 GC01M153588 GC01M154027 GC01M153623 GC01M155076 GC01M128169 |
Summaries
for INSRR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: INSRR_HUMAN, P14616Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated byincreased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB
Gene Wiki entry for INSRR
|
Genomic Views
for INSRR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the INSRR gene promoter:
GR p53 Sp1 AP-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for INSRR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INSRR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21-q23 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q21-q23INSRR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M156809: view genomic region
(about GC identifiers)
Start:
|
156,809,855 bp from pter |
End:
|
156,828,810 bp from pter |
Size:
|
18,956 bases |
Orientation:
|
minus strand |
|
Proteins
for INSRR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: INSRR_HUMAN, P14616 (See
protein sequence)Recommended Name: Insulin receptor-related protein precursor Size: 1297 amino acids; 143720 Da
Subunit: Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to theformation of the ligand-binding domain, while the beta chains carry the kinase domain
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: O60724 Q5VZS3Explore the universe of human proteins at neXtProt for INSRR: NX_P14616
Post-translational modifications:
Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.51
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P14616
4/26 DME Specific Peptides for INSRR (P14616) (see all 26)
INSRR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055030.1
ENSEMBL proteins: ENSP00000357178
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
INSRR for ontologies About GeneDecksing
INSRR Antibody Products:
Assay Products for INSRR: |
Protein
Domains /
Families
for INSRR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
INSRR for domains About GeneDecksing
5/14 InterPro domains/families (see all 14):Graphical View of Domain Structure for InterPro Entry P14616ProtoNet protein and cluster: P14616 5 Blocks protein families: IPB000494 Epidermal growth-factor receptor (EGFR) IPB002011 Receptor tyrosine kinase IPB006211 Furin-like cysteine rich region IPB006212 Furin-like repeat IPB008266 Tyrosine protein kinase
UniProtKB/Swiss-Prot: INSRR_HUMAN, P14616Domain: The extracellular domain is required for sensing alterations in external pHSimilarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamilySimilarity: Contains 3 fibronectin type-III domainsSimilarity: Contains 1 protein kinase domain |
Function
for INSRR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: INSRR_HUMAN, P14616Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated byincreased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKBCatalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate Genatlas biochemistry entry for INSRR:insulin receptor,related receptor,expressed in subsets of neuron,renal distal tubules,enterochromaffin-like cells ofthe fundic stomach and in the islets of pancreas,mutated in a region,involved in the susceptibility to type II noninsulin dependent diabetes
Enzyme Numbers (IUBMB): EC 2.7.10.11 2 EC 2.7.102
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: INSRR (NM_014215) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INSRR |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity |
NAS | 10226785 | | GO:0005524 | ATP binding |
IEA | -- | | GO:0043548 | phosphatidylinositol 3-kinase binding |
IEA | -- | | GO:0043560 | insulin receptor substrate binding |
IEA | -- |
INSRR for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for INSRR:
Animal Models:
Mouse knock-out Insrrtm1Dac for INSRR
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Insrr):
INSRR for phenotypes About GeneDecksing
|
Pathways & Interactions
for INSRR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | GPCR Pathway | | | 2 | Rho Family GTPases | | | 3 | Nanog in Mammalian ESC Pluripotency | | | 4 | Actin Nucleation by ARP-WASP Complex | | | 5 | Akt Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/28 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for INSRR (see all 28)
2 
Kegg Pathways (Kegg details for INSRR):
INSRR for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for INSRR
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/20 Interacting proteins for INSRR (P146163 ENSP000003571784) via UniProtKB, MINT, STRING, and/or I2D (see all 20)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway |
NAS | 10226785 | | GO:0030238 | male sex determination |
IEA | -- | | GO:0031532 | actin cytoskeleton reorganization |
IDA | -- | | GO:0046777 | protein autophosphorylation |
IMP | -- | | GO:0071469 | cellular response to alkalinity |
IDA | -- |
INSRR for ontologies About GeneDecksing
|
Drugs & Compounds
for INSRR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
INSRR for compounds About GeneDecksing
 Browse Tocris compounds for INSRR
2 HMDB Compounds for INSRR About this table
3 Novoseek chemical compound relationships for INSRR gene About this table
Search CenterWatch for drugs/clinical trials and news about INSRR
|
Transcripts
for INSRR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for INSRR gene: NM_014215.2 Unigene Cluster for INSRR: Insulin receptor-related receptor Hs.248138 [show with all ESTs]Unigene Representative Sequence: NM_0142151 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000368195(uc010pht.2 uc009wsj.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: INSRR (NM_014215) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for INSRR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INSRR |
Additional cDNA sequence: AF064078.1 AK310760.1 J05046.1 JQ991924.1 1 DOTS entry: DT.40124245 5 AceView cDNA sequences: NM_014215 J05046 AA706212 AL134339 AF064078
GeneLoc Exon Structure
|
Expression
for INSRR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| INSRR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGGCGGGG
About this image
See INSRR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for INSRR
SOURCE GeneReport for Unigene cluster: Hs.248138
SABiosciences Custom PCR Arrays for INSRR
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INSRR
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat INSRR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INSRR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INSRR | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INSRR |
Orthologs
for INSRR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for INSRR gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
Q9YI41_CHICK6 |
Insulin receptor related tyrosine kinase |
66(a) |
1 ↔ 1 |
25(834823-840939) |
lizard
(Anolis carolinensis) |
Reptilia |
INSRR6 |
-- |
69(a) |
1 ↔ 1 |
GL343640.1(175914-207627) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC685852 |
hypothetical protein MGC68585 |
76.24(n) |
|
BC060457.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG38373 |
insulin-like growth factor receptor |
31(a)
(best of 2) |
|
88D7 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
daf-26 |
Insulin-like receptor Insulin-like receptor subuni... |
14(a) |
possible ortholog |
III(2995755-3028792) |
ENSEMBL Gene Tree for INSRR (if available)
TreeFam Gene Tree for INSRR (if available) |
Paralogs
for INSRR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for INSRR gene
- INSR2 ROR12 ROS12 LTK2 NTRK22 IGF1R2 DDR12 NTRK32
- ROR22 DDR22 MUSK2 ALK2 NTRK12
2 SIMAP similar genes for INSRR using alignment to 2 protein entries: INSRR_HUMAN (see all proteins):IGF1R INSR
INSRR for paralogs About GeneDecksing
|
Genomic Variants
for INSRR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for INSRR (156809855 - 156828810 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for INSRR: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INSRR |
|
Disorders
/ Diseases
for INSRR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
INSRR for disorders About GeneDecksing
OMIM gene information: 147671
OMIM disorders: --
10  diseases for INSRR: About MalaCardsvesicoureteral reflux neurofibrosarcoma prostate cancer cholesterol
neuroblastoma prostatitis neuronitis breast cancer
adenocarcinoma pancreatitis
1 disease from the University of Copenhagen DISEASES database for INSRR:Neurofibrosarcoma 1 Novoseek disease relationship for INSRR gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
7 |
10535406 (3) |
Genetic Association Database (GAD): INSRR
Human Genome Epidemiology (HuGE) Navigator: INSRR (3 documents)
Export disorders for INSRR gene to outside databases
|
Publications
for INSRR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for INSRR gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with INSRR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Primary structure of a putative receptor for a ligand of the insulin family. (PubMed id 2768234)1, 2, 3 Shier P. and Watt V.M. (1989)
- Localization of the insulin receptor-related receptor gene to human chromosome 1. (PubMed id 2249481)1, 3, 9 Shier P....Watt V.M. (1990)
- Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor. (PubMed id 10226785)1, 2, 9 Haenze J.... Kiess W. (1999)
- Correlation of type I insulin-like growth factor receptor (IGF-I-R) and insulin receptor-related receptor (IRR) messenger RNA levels in tumor cell lines from pediatric tumors of neuronal origin. (PubMed id 10535406)1, 9 Elmlinger M.W....Kiess W. (1999)
- Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas. (PubMed id 14654552)1, 9 Weber A....Christiansen H. (2003)
- Characterization of a hybrid receptor formed by dimerization of the insulin receptor-related receptor (IRR) with the insulin receptor (IR): coexpression of cDNAs encoding human IRR and human IR in NIH-3T3 cells. (PubMed id 8916919)1, 9 Jui H.Y....Taylor S.I. (1996)
- Characterization of the endogenous insulin receptor-related receptor in neuroblastomas. (PubMed id 7829525)1, 9 Kovacina K.S. and Roth R.A. (1995)
- The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities. (PubMed id 1326521)1, 9 Zhang B. and Roth R.A. (1992)
- Insulin receptor-related receptor messenger ribonucleic acid: quantitative distribution and localization to subpopulations of epithelial cells in stomach and kidney. (PubMed id 7649121)1, 9 Mathi S.K....Watt V.M. (1995)
- Polymorphism screening of the insulin receptor-related receptor gene (INSRR) on 1q in Pima Indians. (PubMed id 11513557)4, 9 Wolford J.K....Prochazka M. (2001)
|
External Searches for INSRR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing INSRR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing INSRR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing INSRR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for INSRR | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for INSRR gene:
Search GeneIP for patents involving INSRR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for INSRR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for INSRR | | OriGene shRNA RFP for INSRR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for INSRR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for INSRR | | | OriGene Protein Over-expression Lysate for INSRR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for INSRR | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for INSRR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for INSRR | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for INSRR | | OriGene Custom Protein Services for INSRR | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat INSRR | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing INSRR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat INSRR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat INSRR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat INSRR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat INSRR |
| |
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| | | | Search Tocris compounds for INSRR |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | INSRR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for INSRR |
|  |  |  | | | | ThermoFisher Antibodies for INSRR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat INSRR |
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