Aliases for INSRR Gene
External Ids for INSRR Gene
Previous GeneCards Identifiers for INSRR Gene
GeneCards Summary for INSRR Gene
INSRR (Insulin Receptor Related Receptor) is a Protein Coding gene. Diseases associated with INSRR include Podoconiosis and Neurofibrosarcoma. Among its related pathways are Activation of cAMP-Dependent PKA and mTOR signaling pathway (KEGG). GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is IGF1R.
UniProtKB/Swiss-Prot for INSRR Gene
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.