Aliases for INPP5F Gene
External Ids for INPP5F Gene
Previous GeneCards Identifiers for INPP5F Gene
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for INPP5F Gene
INPP5F (Inositol Polyphosphate-5-Phosphatase F) is a Protein Coding gene. Among its related pathways are Inositol phosphate metabolism (KEGG) and Inositol phosphate metabolism (KEGG). GO annotations related to this gene include phosphoric ester hydrolase activity. An important paralog of this gene is SACM1L.
UniProtKB/Swiss-Prot for INPP5F Gene
Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.