Aliases for INPP5F Gene
External Ids for INPP5F Gene
Previous GeneCards Identifiers for INPP5F Gene
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for INPP5F Gene
INPP5F (Inositol Polyphosphate-5-Phosphatase F) is a Protein Coding gene. Among its related pathways are Inositol phosphate metabolism (KEGG) and 3-phosphoinositide degradation. GO annotations related to this gene include phosphoric ester hydrolase activity. An important paralog of this gene is SACM1L.
UniProtKB/Swiss-Prot for INPP5F Gene
Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.